Signal transduction through μκ B-cell receptors expressed on pre-B cells is different from that through B-cell receptors on mature B cells

Immunology

Volumn 88, Issue 4, 1996, Pages 593-599

  Nakamura, T ^a   Koyama, M ^b   Yoneyama, A ^b   Higashihara, M ^b   Kawakami, T ^c   Yamamura, H ^d   Sada, K ^d   Okumura, K ^e   Kurokawa, K ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^d KOBE UNIVERSITY   (Japan)

^e JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN; LYMPHOCYTE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; B LYMPHOCYTE; HUMAN; LYMPHOCYTE FUNCTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

EID: 0030016434     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-681.x     Document Type: Article

References (31)

1. LASSOUED K., NUNEZ C.A., BILLIPS L. et al, (1993) Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation. Cell 73, 73.
2. BROUNS G.S., DE VRIES E., VAN NOESEL C.J.M., MASON D.Y., VAN LIER R.A.W. & BORST J. (1993) The structure of the μ/pseudo light chain complex on human pre-B cells is consistent with a function in signal transduction. Eur J Immunol 23, 1088.
3. MISENER V., DOWNEY G.P. & JONGSTRA J. (1991) The immunoglobulin light chain related protein 25 is expressed on the surface of mouse pre-B cell lines and can function as a signal transducing molecule. Intern Immunol 11, 1129.
4. h-reading frame 2 suppression in mouse precursor B cells. Intern Immunol 6, 21.
5. EHLICH A., SCHAAL S., GU H., KITAMURA D., MULLER W. & RAJEWSKY K. (1993) Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell 72, 695.
6. MA A., FISHER P., DILDROP R, et al. (1992) Surface IgM mediated regulation of RAG gene expression in Eμ-N-myc B cell lines. EMBO J 11, 2727.
7. TSUBATA T., TSUBATA R. & RETM M. (1992) Crosslinking of the cell surface immunoglobulin (μ-surrogate light chains complex) on pre-B cells induces activation of V gene rearrangement at the immunoglobulin κ locus. Intern Immunol 4, 637.
8. KITAMURA D., KUDO A., SCHAAL S., MULLER W., MELCHERS F. & RAJEWSKY K. (1992) A critical role of 25 protein in B cell development. Cell 69, 823.
9. PARRY S.L., HASBOLD J., HOLMAN M. & KLAUS G.G.B. (1994) Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J Immunol 152, 2821.
10. HARTLEY S.B., COOKE M.P., FULCHER D.A. et al. (1993) Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death. Cell 72, 325.
11. OKAMOTO M., MURAKAMI M., SHIMIZU A. et al. (1992) A transgenic model of autoimmune hemolytic anemia. J Exp Med 175, 71.
12. HENDERSHOT L. & LEVITT D. (1984) Analysis of surface μ-chain expression in human lymphoblastoid cell lines that do not produce light chains. J Immunol 132, 502.
13. MARUYAMA S., KUBAGAWA H. & COOPER M.D. (1985) Activation of human B cells and inhibition of their terminal differentiation by monoclonal anti-μ antibodies. J Immunol 135, 192.
14. FUKAMACHI H., YAMADA. N., MIURA. T. et al. (1994) Identification of a protein, SPY75. with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fce RI cross-linking. J Immunol 152, 642.
15. COSTA T.E., FRANKE R.R., SANCHEZ M., MISULOVIN Z. & NUSSENZWEIG, M.C. (1992) Functional reconstruction of an immunoglobulin antigen receptor in T cells. J Exp Med 175, 1669.
16. YATOMI Y., HIGASHIHARA M., OZAKI Y., KUME S. & KUROKAWA K. (1990) Intracellular ionized calcium mobilization of CD9 monoclonal antibody-activated human platelets. Biochem Biophys Res Comm 171, 109.
17. NAKAMURA T., SEKAR M.C., KUBAGAWA H. & COOPER M.D. (1993) Signal transduction in human B cells via Ig-β ligation. Intern Immunol 5, 1309.
18. HEMPEL W.M., SCHATZMAN R.C. & DEFRANCO A.L. (1992) Tyrosine phosphorylation of phospholipase C γ2 upon cross-linking of membrane Ig on mature B lymphocytes. J Immunol 148, 3021.
19. CARTER R.H., PARK D.J., RHEE S.G. & FEARON D.T. (1991) Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes. Proc Natl Acad Sci USA 88, 2475.
20. BIGUET C., WAKASUGI N., MISHAL Z. et al. (1994) Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism. J Biol Chem 269, 28865.
21. OKADA T., SAKUMA L., FUKUI Y., HAZEKI O. & UI M. (1994) Blockage of chemotactic peptide-induces stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J Biol Chem 269, 3563.
22. NAKAMURA T., KUBAGAWA H. & COOPER M.D. (1992) Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci USA 89, 8522.
23. 2+ mobilizing signals when expressed on differentiated B lineage cells. J Immunol 144, 3272.
24. NOMURA J., MATSUO T., KUBOTA E., KIMOTO M. & SAKAGUCHI N. (1991) Signal transmission through the B cell-specific MB-1 molecule at the pre-B cell stage. Intern Immunol 3, 117.
25. 2+ mobilization through distinct pathways. EMBO J 13, 1341.
26. YAMANASHI Y., FUKUI Y., WONGSASANT B. et al. (1992) Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci USA 89, 1118.
27. KUROSAKI T., TAKATA M., YAMANASHI Y. et al. (1994) Syk activation by the src-family tyrosine kinase in the B cell receptor signaling. J Exp Med 179, 1725.
28. YAMANASHI Y., OKADA M., SEMBA T. et al. (1993) Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci USA 90, 3631.
29. WECHSLER R.J. & MONROE J.G. (1995) Immature B lymphocytes are deficient in expression of the src-family kinases p59fyn and p55fgr1. J Immunol 154, 1919.
30. PLEIMAN C.M., ABRAMS C., GAUEN L.T. et al. (1994) Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-α. Proc Natl Acad Sci USA 91, 4268.
31. AOKI Y., ISSELBACHER K.J., CHERAYIL B.J. & PILLAI S. (1994) Tyrosine phosphorylation of Blk and Fyn Src homology 2 domain-binding proteins occurs in response to antigen-receptor ligation in B cells and constitutively in pre-B cells. Proc Natl Acad Sci USA 91, 4204.