Adherence and colonization properties of Vibrio cholerae and diarrhoeagenic Escherichia coli

Indian Journal of Medical Research

Volumn 104, Issue JULY, 1996, Pages 38-51

  Ghose, A C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Bacterial adherence; Diarrheagenic Escherichia coli; Intestinal colonization; Vibrio cholerae

Indexed keywords

ADHESIN; CELL SURFACE RECEPTOR;

BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIUM ADHERENCE; BACTERIUM PILUS; CELL DEATH; CHEMICAL REACTION; COMPARATIVE STUDY; CYTOSKELETON; ESCHERICHIA COLI; FIMBRIA; GASTROINTESTINAL INFECTION; GASTROINTESTINAL MUCOSA; HOST CELL; INTESTINE EPITHELIUM CELL; NONHUMAN; REVIEW; SIGNAL TRANSDUCTION; TARGET CELL; VIBRIO CHOLERAE;

ANIMALS; BACTERIAL ADHESION; DIARRHEA; ESCHERICHIA COLI; HUMANS; INTESTINES; VIBRIO CHOLERAE;

EID: 0030016368     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (160)

1. Beachey EH, editor, Bacterial adherence: receptors and recognition. London : Chapman and Hall, 1980 : 466.
2. Salyers AA, Whitt DD, Bacterial pathogenesis : a molecular approach. Washington, DC : ASM Press, 1994.
3. Finlay BB, Falkow S. Common themes in microbial pathogenicity. Microbial Rev 1989; 53 : 210-30.
4. Yamamoto T, Yokota T. Electron microscopic study of Vibrio cholerae 01 adherence to the mucus coat and villus surface in the human small intestine. Infect Immun 1988; 56 : 2753-9.
5. Manning PA. Molecular analysis of potential adhesins of Vibrio cholerae 01. In: Wadstrom T, Makela PH, Svennerholm AM, Wolf-Watz H, editors. Molecular pathogenesis of gastrointestinal infections. New York: Plenum, 1991; 139-46.
6. Sack RB. Colonization and pathology. In: Barua D, Greenough WB III, editors. Cholera. London: Plenum, 1992; 189-97.
7. Kaper JB, Morris Jr.JG, Levine MM. Cholera. Clin Microbiol Rev 1995; 848-86.
8. Booth BA, Sciortino CV, Finkelstein RA. In: Mirelman D, editor. Adhesins of Vibrio cholerae. New York: John Wiley, 1986; 169-82.
9. Richardson SH. Animal models in cholera research. In: Wachsmuth IK, Blake PA, Olsvik O, editors. Virbro cholerae and cholera : Molecular to global perpectines Washington, DC: ASM Press, 1994; 203-26.
10. Stewart-Tull DES, Ollar RA, Scobie TS. Studies on the Vibrio cholerae mucinase complex. 1. Enzymic activities associated with the complex. J Med Microbiol 1986; 22 : 325-33.
11. Kabir S, Ahmed N. Ali S. Neuraminidase production by Vibrio cholerae 01 and other diarrheagenic bacteria. Infect Immun 1984; 44 : 747-9.
12. Young DB, Broadbent DA. Biochemical characterization of extracellular proteases from Vibrio cholerae. Infect Immun 1982; 37 : 875-83.
13. Pierce NF, Kaper JB, Mekalanos JJ, Cray Jr. WC. Role of cholera toxin in enteric colonization by Vibrio cholerae 01 in rabbits. Infect Immun 1985; 50 : 813-6.
14. Freter R, O'Brien PCM, Macsai MS. Role of chemotaxis in the association of motile bacteria with intestinal mucosa : In vivo studies. Infect Immun 1981; 34 : 234-40.
15. Freter R, Allweiss B, O'Brien PCM, Halstead SA, Macsai MS. Role of chemotaxis in the association of motile bacteria with intestinal mucosa: In vitro studies. Infect Immun 1981; 34 : 241-9.
16. Guentzel MN, Berry LJ. Motility as a virulence factor for Vibrio cholerae. Infect Immun 1975; 11 : 890-7.
17. Richardson K. Roles of motility and flagellar structure in pathogenicity of Vibrio cholerae : analysis of motility mutants in three animal models. Infect Immun 1991; 59 : 2727-36.
18. Attridge SR, Rowley D. The role of the flagellum in the adherence of Vibrio cholerae. J Infect Dis 1983; 147 : 864-72.
19. Teppema JS, Guinee PAM, Ibrahim AA, Paques M, Ruitenberg EJ. In vivo adherence and colonization of Vibrio cholerae strains that differ in hemagglutinating activity and motility. Infect Immun 1987; 55 : 2093-102.
20. Eubanks ER, Guentzel MN, Berry LJ. Evaluation of surface components of Vibrio cholerae as protective immunogens. Infect Immun 1977; 15 : 533-8.
21. Yancy RJ, Willis DL, Berry LJ. Flagella-induced immunity against experimental cholera in adult rabbits. Infect Immun 1979; 25 : 220-8.
22. Hranitzky KW, Mulholland A, Larson AD, Eubanks ER, Hart LT. Characterization of a flagellar sheath protein of Vibrio choleras. Infect Immun 1980; 27 : 597-603.
23. Sinha VB, Jacob A, Srivastava R, Kaper JB, Srivastava BS. Identification of the flagellar antigens of Vibrio choleras El Tor and their role in protection. Vaccine 1993; 11 : 372-5.
24. Fuerst JA, Perry JW. Demonstration of lipopolysaccharide on sheathed flagella of Vibrio cholerae 01 by protein A -gold immunoelectron microscopy. J Bacteriol 1988; 170 : 1488-94.
25. Jones GW, Freter R. Adhesive properties of Vibrio cholerae : Nature of the interaction with isolated rabbit brush border membranes and human erythrocytes. Infect Immun 1976; 14 : 240-5.
26. Yamamoto T, Kamano T, Uchimura M, Iwanaga M, Yokota T. Vibrio cholerae 01 adherence to villi and lymphoid follicle epithelium : in vitro model using formalin-treated human small intestine and correlation between adherence and cell-associated hemagglutinin levels. Infect Immun 1988; 56 : 3241-50.
27. Dasgupta C. Studies on the protective immune mechanism in cholera with special reference to intestinal adhering and hemagglutinating factors of Vibrio cholerae. Ph.D. thesis, Calcutta : Calcutta University, 1986.
28. Sengupta TK. Identification and immunobiological characterization of cell surface proteins responsible for intestinal adhesion and colonization of diarrhoeagenic non-01 Vibrio cholerae. Ph.D. thesis, Calcutta : Calcutta University, 1995.
29. Lankford CE. Factors of virulence of Vibrio cholerae. Ann NY Acad Sci 1960; 88 : 1203-12.
30. Huq A, Small EB, West PA, Huq MI, Rahman R, Colwell RR. Ecology of Vibrio cholerae 01 with special reference to planktonic crustacean copepods. Appl Environ Microbiol 1983; 45 : 275-83.
31. Hanne LF, Finkelstein RA. Characterization and distribution of the hemagglutinins produced by Vibrio cholerae. Infect Immun 1982; 36 : 209-14.
32. Booth BA, Finkelstein RA. Presence of hemogglutinin/protease and other potential virulence factors in 01 and non-01 Vibrio cholerae. J Infect Dis 1986; 154: 183-6.
33. Jonson G, Lebens M, Holmgren J. Cloning and sequencing of Vibrio cholerae mannose-sensitive hemagglutinin pilin gene : localization of mshA within a cluster of type 4 pilin genes. Mol Microbiol 1994; 13 : 109-18.
34. Franzon VL, Barker A, Manning PA. Nucleotide sequence encoding for mannose-fucose-resistant hemagglutinin of Vibrio cholerae 01 and construction of a mutant. Infect Immun 1993; 61 : 3032-7.
35. Attridge SR, Rowley D. The specificity of Vibrio cholerae and the significance of the slime agglutinin as a second mediator of in vitro attachment. J Infect Dis 1983; 147 : 873-81.
36. Ehara M, Ishibashi M, Ichinose Y, Iwanaga M, Shimotori S, Naito T. Purification and partial characterization of fimbriae of Vibrio cholerae 01. Vaccine 1987; 5 : 283-8.
37. Taylor RK, Miller VL, Furlong DB, Mekalanos JJ. The use of phoA gene fusion to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci USA 1987; 84 : 2833-7.
38. Hall RH, Vial PA, Kaper JB, Mekalanos JJ, Levine MM. Morphological studies on fimbriae expressed by Vibrio cholerae 01. Microb Pathog 1988; 4 : 257-65.
39. Jonson G, Holmgren J, Svennerholm AM. Identification of a mannose-binding pilus on Vibrio cholerae ElTor. Microb Pathog 1991; 11 : 433-41.
40. Jonson G, Holmgren J, Svennerholm AM. Analysis of expression of toxin-coregulated pili in classical and ElTor Vibrio cholerae 01 in vitro and in vivo. Infect Immun 1992; 60 : 4278-84.
41. Kaufman MR, Taylor RK. The toxin coregulated pilus : biogenesis and function. In : Wachsmuth IK, Blake PA, Olsvik O, editors. Vibrio cholerae and cholera : molecular to global perspectives. Washington D.C. : ASM Press, 1994; 187-201.
42. Shaw CE, Taylor RK. Vibrio cholerae 0395 tcpA pilin gene sequence and comparison of predicted protein structural features to those of type 4 pilins. Infect Immun 1990; 58 : 3042-9.
43. Otteman KM, Mekalanos JJ. Regulation of cholera toxin expression. In : Wachsmuth IK, Blake PA, Olsvik O, editors. Vibrio cholerae and cholera : molecular to global perspectives. Washington D.C. : ASM Press, 1994; 177-85.
44. Herrington DA, Hall RH, Losonsky G, Mekalanos JJ, Taylor RK, Levine MM. Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J'Exp Med 1988; 168 : 1487-92.
45. Hall RH, Losonsky G, Silveira AP, Taylor RK, Mekalanos JJ, Witham MD et al. Immunogenicity of Vibrio cholerae 01 toxin-coregulated pili in experimental and clinical cholera. Infect Immun 1991; 59 : 2508-12.
46. Rhine JA, Taylor RK. TcpA pilin sequences and colonization requirements for 01 and 0139 Vibrio cholerae. Mol Microbiol 1994; 13 : 1013-20.
47. Iredell JR, Manning PA. Biotype-specific tcpA genes in Vibrio cholerae. FEMS Microbiol Lett 1994; 121 : 47-54.
48. Jonson G, Holmgren J, Svennerholm AM. Epitope differences in toxin coregulated pili produced by classical and ElTor Vibrio cholerae 01. Microb Pathog 1991; 11 : 179-88.
49. Sun D, Mekalanos JJ, Taylor RK. Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model. J Infect Dis 1990; 161 : 1231-6.
50. Voss E, Attridge SR. In vitro production of toxin-coregulated pili by Vibrio cholerae ElTor. Microb Pathog 1993: 15 : 255-68.
51. Ogierman MA, Zabihi S, Mourtzios L, Manning PA. Genetic organization and sequence of the promoter -distal region of the tcp gene cluster of Vibrio cholerae. Gene 1993; 126 : 51-60.
52. Osek J. Svennerholm AM, Holmgren J. Protection against Vibrio cholerae ElTor infection by specific antibodies against mannose-binding hemagglutinin pili. Infect Immun 1992; 60 : 4961-4.
53. Finn TM, Reiser J, Germanier R, Cryz Jr. SJ. Cell-associated hemagglutinin-deficient mutant of Vibrio cholerae. Infect Immun 1987; 55 : 942-6.
54. Hase CC, Bauer ME, Finkelstein RA. Genetic characterization of MSHA-negative mutants of Vibrio cholerae derived by Tn5 mutagenesis. Gene 1994; 150 : 17-25.
55. Mukhopadhyay S, Ghosh C, Ghose AC. Phenotypic expression of a mannose-sensitive hemagglutinin in a Vibrio cholerae 01 ElTor strain and evaluation of its role in intestinal adherence and colonisation. FEMS Microbiol Lett 1996; 138 : 227-32.
56. Ehara M, Ichinose Y, Hirayama T, Kurazono H, Hidaka Y, Morita K et al. Cloning and sequencing of the gene encoding Vibrio cholerae 01 fimbrial subunit (fimbrillin). FEMS Microbiol Lett 1994; 123 : 185-92.
57. Iwanaga M, Nakasone N, Yamashiro T, Higa N. Pili of Vibrio cholerae widely distributed in serogroup 01 strains. Microbiol Immunol 1993; 37 : 23-8.
58. Chitnis DS, Sharma KD, Kamat RS. Role of somatic antigen of Vibrio cholerae in adhesion to intestinal mucosa. J Med Microbiol 1982; 15 : 53-61.
59. Majumdar AS, Dutta P, Dutta D, Ghose AC. Antibacterial and antitoxin responses in the serum and milk of cholera patients. Infect Immun 1981; 32: 1-8.
60. Svennerholm AM, Jertborn M, Gothefors L, Karim AM MM, Sack DA, Holmgren J. Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunit - whole cell vaccine. J Infect Dis 1984; 149 : 884-93.
61. Svennerholm AM, Jonson G, Holmgren J. Immunity to Vibrio cholerae infection. In: Wachsmuth IK, Blake PA, Olsvik O, editors. Vibrio cholerae and cholera : molecular to global perspectives. Washington D.C. : ASM Press, 1994; 257-71.
62. Ghose AC, Dasgupta C. Protective antigens of Vibrio cholerae. In: Talwar GP, editor. Progress in vaccinology. New York : Springer-Verlag, 1989; 137-50.
63. Sears SD, Richardson K, Young C, Parker CD, Levine MM. Evaluation of the human immune response to Outer membrane proteins of Vibrio cholerae. Infect Immun 1984; 44 : 439-44.
64. Richardson K, Kaper JB, Levine MM. Human immune response to Vibrio cholerae 01 whole cells and isolated outer membrane antigen. Infect Immun 1989; 57 : 495-501.
65. Sengupta DK, Sengupta TK, Ghose AC. Antibodies to outer membrane proteins of Vibrio cholerae induce protection by inhibition of intestinal colonization of vibrios. FEMS Microbiol Immunol 1992; 89 : 261-6.
66. Sengupta DK, SenguptaTK, Ghose AC. Major outer membrane proteins of Vibrio cholerae and their role in induction of protective immunity through inhibition of intestinal colonization. Infect Immun 1992; 60 : 4848-55.
67. Sciortino CV. Protection against infection with Vibrio cholerae by passive transfer of monoclonal antibodies to outer membrane antigens. J Infect Dis 1989; 160 : 248-52.
68. Goldberg MB, DiRita VJ, Calderwood SB. Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis. Infect Immun 1990; 58 : 55-60.
69. Sperandio V, Giron JA, Silveira WD, Kaper JB. The OmpU outer membrane protein, a potential adherence factor of Vibrio cholerae. Infect Immun 1995; 63 : 4433-8.
70. Peterson KM, Mekalanos JJ. Characterization of the Vibrio cholerae ToxR regulon : Identification of novel genes involved in intestinal colonization. Infect Immun 1988; 56 : 2822-9.
71. Pearson GDN, Woods A, Chiang SL, Mekalanos JJ. CTX genetic element encodes a site - specific recombination system and an intestinal colonization factor, Proc Natl Acad Sci USA 1993; 90 : 3750-4.
72. Levine MM, Pierce NF, Immunity and vaccine development. In: Barua D, Greenough WB III, editors. Cholera. London: Plenum 1992; 285-327.
73. Majumdar AS, Ghose AC. Evaluation of the biological properties of different classes of human antibodies in relation to cholera. Infect Immun 1981; 32 : 9-14.
74. Shimada T, Nair GB, Deb BC, Albert MJ, Sack RB, Takeda Y. Outbreak of Vibrio cholerae non-01 in India and Bangladesh. Lancet 1993; 341 : 1346-7.
75. Hall RH, Khambaty FM, Kothary M, Keasler SP. Non-01 Vibrio cholerae. Lancet 1993; 342 : 430.
76. Waldor MK, Mekalanos JJ. Emergence of a new cholera pandemic: Molecular analysis of virulence determinants in Vibrio cholerae 0139 and development of a live vaccine prototype. J Infect Dis 1994; 770 : 278-83.
77. Bik EM, Bunschoten AE, Gouw RD, Mooi FR. Genesis of the novel epidemic Vibrio cholerae 0139 strain : evidence for horizontal transfer of genes involved in polysaccharide synthesis. EMBO J 1995; 14 : 209-16.
78. Comstock LE, Maneval Jr. D, Panigrahi P, Joseph A, Levine MM, Kaper JB et al. The capsule and O antigen in Vibrio cholerae 0139 Bengal are associated with a genetic region not present in Vibrio cholerae 01. Infect Immun 1995; 63 : 317-23.
79. Waldor MK, Mekalanos JJ. Vibrio cholerae 0139 specific gene sequences. Lancet 1994; 343 : 1366.
80. Nandy RK, Sengupta TK, Mukhopadhyay S, Ghose AC. A comparative study of the properties of Vibrio cholerae 0139, 01 and other non-01 strains. J Med Microbiol 1995; 42 : 251-7.
81. Albert MJ, Alam K, Rahaman AS, Huda S, Sack RB. Lack of cross-protection against diarrhea due to Vibrio cholerae 01 after oral immunization of rabbits with V. cholerae 0139 Bengal. J Infect Dis 1994; 169 : 709-10.
82. Nandy RK, Albert MJ, Ghose AC. Serum antibacterial and antitoxin responses in clinical cholera caused by Vibrio cholerae 0139 Bengal and evaluation of thier importance in protection. Vaccine 1996 (in press).
83. Stroeher UH, Jedani KE, Dredge BK, Morona R, Brown MH, Karagcorgas LE et al. Genetic rearrangements in the rfb regions of Vibrio cholerae 01 and 0139. Proc Natl Acad Sci USA 1995; 92 : 10374-8.
84. Sengupta TK, Sengupta DK, Nair GB, Ghose AC. Epidemic isolates of Vibrio cholerae 0139 express antigenically distinct types of colonization pili. FEMS Microbiol Lett 1994; 118 : 265-72.
85. Yamashiro T, Nakasone N, Honma Y, Albert MJ, Iwanaga M. Purification and characterization of Vibrio cholerae 0139 fimbriae. FEMS Microbiol Lett 1994; 115 : 247-52.
86. Johnson JA, Salles CA, Panigrahi P, Albert MJ, Wright AC, Johnson RJ et al. Vibrio cholerae 0139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences. Infect Immun 1994; 62 : 2108-10.
87. Weintraub A, Widmaim G, Jansson PE, Jansson M, Hultenby K, Albert MJ. Vibrio cholerae 0139 Bengal possesses a capsular polysaccharide which may confer increased virulence. Microb Pathog 1994; 16 : 235-41.
88. Sengupta DK, Boesman-Finkelstein M, Finkelstein RA. Antibody against the capsule of Vibrio cholerae 0139 protects against experimental challenge. Infect Immun 1996; 64 : 343-5.
89. Hisatsune K, Kondo S, Isshiki Y, Iguchi T, Kawamata Y, Shimada T. O-antigenic lipopolysaccharide of Vibrio cholerae 0139 Bengal, a new epidemic strain for recent cholera in the Indian subcontinent. Biochem Biophys Res Commun 1993; 196: 1309-15.
90. Waldor MK, Colwell R, Mekalanos J. The Vibrio cholerae 0139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinants. Proc Natl Acad Sci USA 1994; 91 : 11388-92.
91. Yamamoto T, Albert MJ, Sack RB. Adherence to the human small intestines of capsulated Vibrio cholerae 0139. FEMS Microbiol Lett 1994; 119 : 229-36.
92. Morris Jr. JG. Non-O group 1 Vibrio cholerae strains not associated with epidemic diseases. In: Wachsmuth IK Blake PA, Olsvik O, editors. Vibrio cholerae and cholera : molecular to global perspectives. Washington D.C. : ASM Press, 1994; 103-15.
93. Spira WM, Fedorka-Cray PJ, Pettebone P. Colonization of the rabbit small intestine by clinical and environmental isolates of non-01 Vibrio cholerae and Vibrio mimicus. Infect Immun 1983; 41 : 1175-83.
94. Datta-Roy K, Banerjee K, De SP, Ghose AC. Comparative study of expression of hemaggutinins, hemolysins, and enterotoxins by clinical and environmental isolates of non-01 Vibrio cholerae in relation of their enteropathogenicity. Appl Environ Microbiol 1986; 52 : 875-9.
95. Morris Jr. JG, Takeda T, Tall BD, Losonsky GA, Bhattacharya SR, Forrest BD. et al. Experimental non-0 group 1 Vibrio cholerae gastroenteritis in humans. J Clin Invest 1990; 85 : 697-705.
96. Datta K. Immunological studies on the enteropathogenic factors of non-01 Vibrio cholerae isolated from clinical and environmental sources. Ph.D. thesis, Calcutta : Calcutta University, 1988.
97. Morris Jr. JG. Non-0 group 1 Vibrio cholerae a look at the epidemiology, of an occasional pathogen. Epidemiol Rev 1990; 12 : 179-91.
98. Honda T, Kasemsuksakul K, Oguchi T, Kohda M, Miwatani T. Production and partial characterizaton of pili on non-01 Vibrio cholerae. J Infect Dis 1988; 157 : 217-8.
99. Nakasone N, Iwanaga M. Pili of Vibrio cholerae non-01. Infect Immun 1990; 58 : 1640-6.
100. Yamashiro T, Nakasone N, Iwanaga M. Purification and characterization of pili of a Vibrio cholerae non-01 strain. Infect Immun 1993; 61 : 5398-400.
101. Sengupta TK, Sengupta DK, Ghose AC. A 20-kDa pilus protein with haemagglutination and intestinal adherence properties expressed by a clinical isolate of non-01 Vibrio cholerae. FEMS Microbiol Lett 1993; 112 : 237-42.
102. Banerjee KK, Ghosh AN, Dutta-Roy K, Pal, S.C. Ghose AC. Purification and characterization of a novel hemagglutinin from Vibrio cholerae. Infect Immun 1990; 58 : 3698-705.
103. Johnson JA, Panigrahi P, Morris Jr. JG. Non-01 Vibrio cholerae NRT36S produces a polysaccharide capsule that determines colony morphology, serum resistance and virulence in mice. Infect Immun 1992; 60 : 864-9.
104. Levine MM. Escherichia coli that cause diarrhoea : enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic and enteroadherent. J Infect Dis 1987; 155 : 377-89.
105. Black RE. Epidemiology of traveler's diarrhoea and relative importance of various pathogens. Rev Infect Dis 1990; 12 Suppl 1: 873-9.
106. Gaastra W, De Graaf FK. Host-specific fimbrial adhesins of noninvasiveenterotoxigenic Escherichiacoli strains. Microbiol Rev 1982; 46 : 129-61.
107. Evans D, Evans D. Colonization factor antigens of human pathogens. Curr Top Microbiol Immunol 1990; 151 : 121-45.
108. McConnell MM, Thomas LV, Willshaw GA, Smith HR, Rowe B. Genetic control and properties of coli surface antigens of colonization factor antigen IV (PCF8775) of enterotoxigenic Escherichia coli. Infect Immun 1988; 56 : 1974-80.
109. Buhler T, Hoschutzky H, Jann K. Analysis of colonization factor antigen I, an adhesion of enterotoxigenic Escherichia coli 078:H11 : fimbrial morphology and location of the receptor binding site. Infect Immun 1991; 59 : 3876-82.
110. Smyth CJ. Serologically distinct fimbriae on enterotoxigenic Escherichia coli on serotype 06 : K15 : H16 or H. FEMS Microbiol Lett 1984; 21 : 51-7.
111. Honda T, Arita M, Miwatani T. Characterization of new hydrophobic pili of human enterotoxigenic Escherichia coli: a possible new colonization factor. Infect Immun 1984; 43 : 959-65.
112. McConnell MM. Newly characterized putative colonization factors of human enterotoxigenic Escherichia coli. FEMS Symp 1991; 58 : 79-85.
113. Giron JA, Levine MM, Kaper JB. Longus: a long pilus ultrastructure produced by human enterotoxigenic Escherichia coli. Mol Microbiol 1994; 12 : 71-82.
114. Darfeuille-Michaud A, Aubel D, Chauviere G, Rich C, Bourges M, Servin A et al. Adhesion of enterotoxigenic Escherichia coli to the human colon carcinoma cell line Caco-2 in culture. Infect Immun 1990; 58 : 893-902.
115. Klemm P. Fimbrial adhesins of Escherichia coli. Rev Infect Dis 1985; 7 : 321-40.
116. Rudin A, McConnell MM, Svennerholm AM. Monoclonal antibodies against enterotoxigenic Escherichia coli colonization factor antigen I (CFA 1) that cross reacts immunologically with heterologous CFAs. Infect Immun 1994; 62 : 4339-46.
117. Levine MM, Edelman R. Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea : epidemiology and pathogenesis. Epidemiol Rev 1984; 6 : 31-51.
118. Donnenberg MS, Kaper JB, Enteropathogenic Escherichia coli. Infect Immun 1992; 60 : 3953-61.
119. Nataro JP, Scaletsky ICA, Kaper JB, Levine MM, Trabulsi LR. Plasmid-mediated factors conferring diffuse and localized adherence of enteropathogenic Escherichia coli. Infect Immun 1985; 48 : 378-83.
120. Levine MM, Nataro JP, Karch H, Baldini MM, Kaper JB, Black RE et al. The diarrheal response of humans to some classic serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor. J Infect Dis 1985; 152 : 550-9.
121. Rosenshine I, Donnenberg MS, Kaper JB, Finlay BB. Signal exchange between enteropathogenic Escherichia coli (EPEC) and epithelial cells : EPEC induce tyrosine phosphorylation of host cell protein to initiate cytoskeletal rearrangement and bacterial uptake. EMBO J 1992; 11 : 3551-60.
122. Baldwin TJ, Ward W, Aitken A, Knutton S, Williams PH. Elevation of intracellular free calcium levels in HEp-2 cells infected with enteropathogenic Escherichia coli. Infect Immun 1991; 59 : 1599-1604.
123. Knutton S, Baldwin T, Williams PH, McNeish AS. Actin accumulation at sites of bacterial adhesion to tissue culture cells : basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coli. Infect Immun 1989; 57 : 1290-8.
124. Finlay BB, Rosenshine I, Donnenberg MS, Kaper JB. Cytoskeletal composition of attaching and effacing lesions asociated with enteropathogenic Escherichia coli adhrence to HeLa cells. Infect Immun 1992; 60 : 2541-3.
125. Donnenberg MS, Donohue-Rolfe A, Keusch GT. Epithelial cell invasion : an overlooked property of enteropathogenic Escherichia coli (EPEC) associated with the EPEC adherence factor. J Infect Dis 1989; 760 : 452-9.
126. Giron JA, Ho ASY, Schoolnik GK. An inducible bundle-forming pilus of enteropathogenic Escherichia coli. Science 1991; 254 : 710-3.
127. Donnenberg MS, Giron JA, Nataro JP, Kaper JB. A plasmid encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localised adherence. Mol Microbiol 1992; 6 : 3427-37.
128. Sohel I, Puente JL, Murray WJ, Vuopio-Varkila J, Schoolnik GK. Cloning and characterization of the bundle-forming pilin gene of enteropathogenic Escherichia coli and its distribution in Salmonella serotypes. Mol Microbiol 1993; 7 : 563-75.
129. Jerse AE, Kaper JB, The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid. Infect Immun 1991; 59 : 4302-9.
130. Jerse AE, Gicquelais KG, Kaper JB. Plasmid and chromosomal elements involved in the pathogenesis of attaching and effacing Escherichia coli. Infect Immun 1991; 59 : 3869-75.
131. Donnenberg MS, Yu J, Kaper JB. A second chromosomal gene necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells. J Bacteriol 1993; 175 : 4670-80.
132. Vida F, Rosenshine I, Donnenberg MS, Finlay BB. The eae B gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells. Infect Immun 1994; 16 : 3038-40.
133. Bhan MK, Raj P, Levine MM, Kaper JB, Bhandari N, Srivastav Ra et al. Enteroaggregative Escherichia coli associated with persistent diarrhoea in a cohort of rural children in India. J Infect Dis 1989; 159 : 1061-4.
134. Cravioto A, Tello A, Navarro A, Ruiz J, Villafan H, Uribe F et al. Association of Escherichia coli HEp-2 adherence patterns with type and duration of diarrhoea. Lancet 1991; 337 : 262-4.
135. Savarino SJ, Fasano A, Watson J, Martin BM, Levine MM, Guandalini S et al. Enteroaggregative Escherichia coli heatstable enterotoxin 1 represents another subfamily of Esch. coli heat-stable toxin. Proc Natl Acad Sci USA 1993; 90: 3093-7.
136. Baldwin TJ, Knutton S, Sellers L, Hernandez HAM, Aitken A, Williams PH. Enteroaggregative Escherichia coli strains secrete a heat-labile toxin antigenically related to E. coli hemolysin. Infect Immun 1992; 60 : 2092-5.
137. Nataro J, Kaper JB, Robins-Browne R, Prado V, Levine MM. Patterns of adherence of diarrhoeagenic Escherichia coli to HEp-2 cells. Pediatr Infect Dis J 1987; 6 : 829-31.
138. Baudry B, Savarino SJ, Vial P, Kaper JB, Levine MM. A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently discovered diarrhoeal pathogen. J Infect Dis 1990; 161 : 1249-51.
139. Knutton S, Shaw RK, Bhan MK, Smith HR, McConnell MM, Cheasty T et al. Ability of enteroaggregative Escherichia coli strains to adhere in vitro to human intestinal mucosa. Infect Immun 1992; 60 : 2083-91.
140. Pal R, Ghose AC. Identification of plasmid-encoded mannose-resistant hemagglutinin and HEp-2 and HeLa cell adherence factors of two diarrhoeagenic Escherichia coli strains belonging to an enteropathogenic serogroup. Infect Immun 1990; 58 : 1106-13.
141. Yamamoto T, Endo S, Yokota T, Echeverria P. Characteristics of adherence of enteroaggregative Escherichia coli to human and animal mucosa. Infect Immun 1991; 59 : 3722-39.
142. Vial PA, Robins-Browne R, Lior H, Prado V, Kaper JB, Nataro JP et al. Characterization of enteroadherent aggregative Escherichia coli, a putative agent of diarrheal disease. J Infect Dis 1988; 158 : 70-9.
143. Nataro JP, Deng Y, Maneval DR, German AL, Martin WC, Levine MM. Aggregative adherence fimbriae I of enteroaggregative Escherichia coli mediate adherence to HEp-2 cells and hemagglutination of human erythrocytes. Infect Immun 1992; 60 : 2297-304.
144. Old DC, Tavendale A, Yakubu DE. Some strains of Escherichia coli of putative enteroadherent-aggregative serotypes produce an unusual fibrillar hemagglutinin. FEMS Microbiol Lett 1989; 59 : 87-92.
145. Nandy RK, Barari SK, Ghose AC. Expression of antigenically distinct fimbriae with hemagglutination and HeLa cell adherence properties by an enteroaggregative Escherichia coli strain belonging to the enteropathogenic serogroup. FEMS Immunol Med Microbiol 1994; 9 : 143-50.
146. Savarino SJ, Fox P, Yikang D, Nataro JP. Identification and characterization of a gene cluster mediating enteroaggregative Escherichia coli aggregative adherence fimbria I biogenesis. J Bacteriol 1994; 176 : 4949-57.
147. Nataro JP, Yikang D, Yingkang D, Walker K. AggR, a transeriptional activator of aggregative adherence fimbria 1 expression in enteroaggregative Escherichia coli. J Bacteriol 1994; 176 : 4691-9.
148. Riley LW. The epidemiologic, clinical and microbiologic features of hemorrhagic colitis. Ann Rev Microbiol 1987; 41 : 383-407.
149. Tzipori S; Karch H, Wachsmuth KI, Robins-Browne RM, O'Brien AD, Lior H et al. Role of a 60 Megadalton plasmid and shiga-like toxins in the pathogenesis of infection caused by enterohemorrhagic Escherichia coli 0157 : H7 in gnotobiotic piglets. Infect Immun 1987; 55 : 3117-25.
150. Tesh VL, O'Brien AD. Adherence and colonization mechanism of enteropathogenic and enterohemorrhagic Escherichia coli. Microb Pathog 1992: 12 : 245-54.
151. Karch H, Heesemann J, Laufs R, O'Brien AD, Tacket CO, Levine MM. A plasmid of enterohemorrhagic Escherichia coli 0157:H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells. Infect Immun 1987; 55 : 455-61.
152. Beebakhee G, Louie M, De Azavedo J. Brunton J. Cloning and nucleotide sequence of the eae gene homologue from enterohemorrhagic Escherichia coli serotype 0157:H7. FEMS Microbiol Lett 1992; 91 : 63-8.
153. Yu J, Kaper J. Cloning and Characterization of the eae gene of enterohaemorrhagic Escherichia coli 0157:H7. Mol Microbiol 1992; 6 : 411-7.
154. Donnenberg MS, Tzipori S, Mckee ML, O'Brien AD, Alroy J, Kaper JB. The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model. J Clin Invest 1993; 92 : 1418-24.
155. Oelschlaeger TA, Barrett TJ, Kopecko DJ. Some structure and processes of human epithelial cells involved in uptake of enterohemorrhagic Escherichia coli 0157:H7 strains. Infect Immun 1994; 62 : 5142-50.
156. Small PLC, Falkow S. Identification of regions on a 230 kilobase plasmid from enteroinvasive Escherichia coli that are required for entry into HEp-2 cells. Infect Immun 1988; 56 : 225-9.
157. Hale TL, Oaks EV, Formal SB. Identification and antigenic characterization of virulence-associated, plasmid-coded proteins of Shigella spp. and enteroinvasive Escherichia coli. Infect Immun 1985; 50 : 620-9.
158. Makino S, Sasakawa C, Yoshikawa M. Genetic relatedness of the basic replicon of the virulence plasmid in shigellae and enteroinvasive Escherichia coli. Microb Pathog 1998; 5 : 267-74.
159. Pal T, Formal SB, Hale TL. Characterization of virulence marker antigen of Shigella spp and enteroinvasive Escherichia coli. J Clin Microbiol 1989; 27 : 561-3.
160. Sansonetti PJ. Genetic and molecular basis of epithelial cell invasion by Shigella species. Rev Infect Dis 1991; 13 Suppl.4 : S285-92.