Myocardial viability in cases with persistent perfusion defects on the dipyridamole thallium-201 scintigram. A comparative study with autopsy findings

Japanese Heart Journal

Volumn 37, Issue 3, 1996, Pages 301-316

  Nakayama, Masafumi ^b   Ohkawa, Shin Ichiro ^a   Tanno, Munehiko ^a   Yamada, Hideo ^a   Mashima, Saburo ^b  

^a Tokyo Metropolitan Institute of Gerontology   (Japan)

^b SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

Author keywords

Myocardial fibrosis; Myocardial infarction; Pathology; Percent thallium 201 uptake; Single photon emission computed tomography

Indexed keywords

DIPYRIDAMOLE; THALLIUM 201;

AGED; ARTICLE; AUTOPSY; CLINICAL ARTICLE; COMPARATIVE STUDY; CORRELATION FUNCTION; DIAGNOSTIC ACCURACY; EXERCISE TEST; FEMALE; HEART INFARCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE FIBROSIS; HEART SCINTISCANNING; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TIME;

EID: 0030016103     PISSN: 00214868     EISSN: None     Source Type: Journal    
DOI: 10.1536/ihj.37.301     Document Type: Article

References (28)

1. Beller GA. Diagnostic accuracy of thallium-201 myocardial perfusion imaging. Circulation 1991; 84 (suppl I): I-1-6.
2. Bonow RO, Dilsizian V Thallium 201 for assessment of myocardial viability. Semin Nucl Med 1991; 21: 230-41.
3. Brown KA. Prognostic value of thallium-201 myocardial perfusion imaging. A diagnostic tool comes of age. Circulation 1991; 83: 363-81.
4. Pohost GM, Zir LM, Moore RH, McKusick KA, Guiney TE, Beller GA. Differentiation of transiently ischemic from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation 1977; 55: 294-302.
5. Tillisch J, Brunken R, Marshall R, et al. Reversibility of cardiac wall-motion abnormalities predicted by positron tomography. New Engl J Med 1986; 314: 884-8.
6. 18F-fluorodeoxyglucose. Circulation 1991; 83: 26-37.
7. Gutman J, Berman DS, Freeman M, et al. Time to completed redistribution of thallium-201 in exercise myocardial scintigraphy: relationship to the degree of coronary artery stenosis. Am Heart J 1983; 106: 989-95.
8. Tamaki N, Yonekura Y, Yamashita K, et al. Relation of left ventricular perfusion and wall motion with metabolic activity in persistent defects on thallium-201 tomography in healed myocardial infarction. Am J Cardiol 1988; 62: 202-8.
9. Dilsizian V, Rocco TP, Freedman NMT, Leon MB, Bonow RO. Enhanced detection of ischemic but viable myocardium by the reinjection of thallium after stress-redistribution imaging. New Engl J Med 1990; 323: 141-6.
10. Iskandrian AS, Hakki A-H, Kane SA, et al. Rest and redistribution thallium-201 myocardial scintigraphy to predict improvement in left ventricular function after coronary arterial bypass grafting. Am J Cardiol 1983;51:1332-6.
11. Gibson RS, Watson DD, Taylor GJ, et al. Prospective assessment of regional myocardial perfusion before and after coronary revascularization surgery by quantitative thallium-201 scintigraphy. J Am Coll Cardiol 1983; 1: 804-15.
12. Liu P, Kiess MC, Okada RD, et al. The persistent defect on exercise thallium imaging and its fate after myocardial revascularization: Does it represent scar or ischemia? Am Heart J 1985; 110: 996-1001.
13. Kiat H, Berman DS, Maddahi J, et al. Late reversibility of tomographic myocardial thallium-201 defects: An accurate marker of myocardial viability. J Am Coll Cardiol 1988; 12: 1456-64.
14. 201Tl scintigraphy in the evaluation of prognosis after myocardial infarction. Circulation 1991; 84 (suppl I): I-132-9.
15. Botvinick EH, Dae MW. Dipyridamole perfusion scintigraphy. Semin Nucl Med 1991; 21: 242-65.
16. Sugiura M and Okada R. A clinicopathological study on the natural history of myocardial infarction in the aged. Jpn Circ J 1972; 36: 2-5.
17. Brunken R, Schwaiger M, Grover-McKay M, Phelps ME, Tillisch J, Schelbert HR. Positron emission tomography detects tissue metabolic activity in myocardial segments with persistent thallium perfusion defects. J Am Coll Cardiol 1987; 10: 557-67.
18. Bodenheimer MM, Banka VS, Hermann GA, Trout RG, Pasdar H, Helfant RH. Reversible asynergy. Histopathologic and electrographic correlations in patients with coronary artery disease. Circulation 1976, 53: 792-6.
19. Bulkley BH, Silverman K, Weisfeldt ML, Burow R, Pond M, Becker LC. Pathologic basis of thallium-201 scintigraphic defects in patients with fatal myocardial injury. Circulation 1979; 60: 785-92.
20. Cloninger KG, DePuey EG, Garcia EV, et al. Incomplete redistribution in delayed thallium-201 single photon emission computed tomographic (SPECT) images: An overestimation of myocardial scarring. J Am Coll Cardiol 1988; 12: 955-63.
21. Mori T, Minamiji K, Kurogane H, Ogawa K, Yoshida Y. Rest-injected thallium-201 imaging for assessing viability of severe asynergic regions. J Nucl Med 1991; 32: 1718-1724.
22. 201Tl defects. Circulation 1992; 86: 1357-69.
23. Granato JE, Watson DD, Flanagan TL, Gascho JA, Beller GA Myocardial thallium-201 kinetics during coronary occlusion and reperfusion: Influence of method of reflow and timing of thallium-201 administration. Circulation 1986; 73: 150-60.
24. Grunwald AM, Watson DD, Holzgrefe HH Jr, Irving JF, Beller GA. Myocardial thallium-201 kinetics in normal and ischemic myocardium. Circulation 1981; 64: 610-8.
25. Verani MS, Jhingran S, Attar M, Rizk A, Quinones MA, Miller RR Post-stress redistribution of thallium-201 in patients with coronary artery disease, with and without prior myocardial infarction. Am J Cardiol 1979; 43: 1114-22.
26. Cooper R, Puri S, Francis CK, Spencer RP. Role of coronary artery disease and collateral circulation in redistribution of thallium-201. Clin Nucl Med 1980; 5: 292-8.
27. Becker LC, Rogers WJ Jr, Links JM, Corn C. Limitations of regional myocardial thallium clearance for identification of disease in individual coronary arteries. J Am Coll Cardiol 1989, 14: 1491-500.
28. Schwarz F, Schaper J, Becker V, Kübler W, Flameng W. Coronary collateral vessels: Their significance for left ventricular histologie structure. Am J Cardiol 1982; 49: 291-5.