Attitudes towards bipolar disorder and predictive genetic testing among patients and providers

Journal of Medical Genetics

Volumn 33, Issue 7, 1996, Pages 544-549

  Smith, Lauren B ^a   Sapers, Benjamin ^a   Reus, Victor I ^a   Freimer, Nelson B ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Manic depression; Presymptomatic testing

Indexed keywords

ADULT; ARTICLE; ATTITUDE; CLINICAL FEATURE; CONTROLLED STUDY; DECISION MAKING; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENETIC SCREENING; HEALTH CARE PERSONNEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; MENTAL HEALTH; PREGNANCY TERMINATION; PRIORITY JOURNAL; QUESTIONNAIRE; SOCIAL SUPPORT;

EID: 0030015982     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.33.7.544     Document Type: Article

References (26)

1. Croyle RT, Lerman C. Interest in genetic testing for colon cancer susceptibility: cognitive and emotional correlates. Prev Med 1993;22:284-92.
2. Lerman C, Daly M, Masny A, et al. Attitudes about genetic testing for breast-ovarian cancer susceptibility. J Clin Oncol 1994;12:843-50.
3. Kessler S, Field T, Worth L, et al. Attitudes of persons at risk for Huntington disease toward predictive testing. Am J Med Genet 1987;26:259-70.
4. Benjamin CM, Colley A, Donnai D, et al. Neurofibromatosis type 1 (NF1): knowledge, experience, and reproductive decisions of affected patients and families. J Med Genet 1993;30:567-74.
5. Rona RJ, Beech R, Mandalia S, et al. The influence of genetic counselling in the era of DNA testing on knowledge, reproductive intentions and psychological wellbeing. Clin Genet 1994;46:198-204.
6. Goodwin FK, Jamison KR. Manic-depressive illness. New York: Oxford University Press, 1990.
7. Bertelsen A, Harvald B, Hauge M. A Danish twin study of manic-depressive disorders. Br J Psychiatry 1977;130:330-51.
8. Berrettini WH, Ferraro TN, Goldin LR, et al. Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. Proc Natl Acad Sci USA 1994;91:5918-21.
9. Freimer NB, Reus VI, Escamilla ME, et al. Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-23. Nature Genet 1996;12:436-11.
10. Targum SD, Dibble ED, Davenport YB, et al. The family attitudes questionnaire: patients' and spouses' views of bipolar illness. Arch Gen Psychiatry 1981;38:562-8.
11. Thies U, Bockel B, Bochdalofsky V. Attitudes of neurologists, psychiatrists, and psychotherapists towards predictive testing for Huntingdon's disease in Germany. J Med Genet 1993;30:1023-7.
12. Parsons EP, Clarke AJ. Genetic risk: women's understanding of carrier risks in Duchenne muscular dystrophy. J Med Genet 1993;30:562-6.
13. Evers-Kiebooms G, Swerts A, Cassiman JJ, et al. The motivation of at-risk individuals and their partners in deciding for or against predictive testing for Huntington's disease. Clin Genet 1989;35:29-10.
14. Bloch M, Fahy M, Fox S, et al. Predictive testing for Huntington disease. II. Demographic characteristics, life style patterns, attitudes, and psychosocial assessments of the first fifty-one candidates. Am J Med Genet 1989;32:217-24.
15. Adler NE, Keyes S, Robertson P. Psychological issues in new reproductive technologies: pregnancy-inducing technology and diagnostic screening. In: Rodin J, Collins A, eds. Women and new reproductive technologies: medical, psychosocial, legal, and ethical dilemmas. Hillsdale NJ: Lawrence Erlbaum, 1991.
16. Mitchell J, Scriver CR, Clow CL, et al. What young people think and do when the option for cystic fibrosis carrier testing is available. J Med Genet 1993;30:538-42.
17. Bekker H, Denniss G, Modell M, et al. The impact of population based screening for carriers of cystic fibrosis. J Med Genet 1994;31:364-8.
18. Levy M, Pirson Y, Simon P, et al. Evaluation in patients with Alport syndrome of knowledge of the disease and attitudes toward prenatal diagnosis. Clin Nephrol 1994;42:211-20.
19. Green J, Murton F, Statham H. Psychological issues raised by a familial ovarian cancer register. J Med Genet 1993;30:575-9.
20. Marshall E. A tough line on genetic screening. Science 1993;262:984-5.
21. Wertz DC, Fanos JH, Reilly PR. Genetic testing in children and adolescents: who decides? JAMA 1994;272:875-81.
22. New York Times. Should children know of disease risk? Debate rages over genetic knowledge. The San Francisco Chronicle, 27 September 1994.
23. Adam S, Wiggins S, Whyte P, et al. Five year study of prenatal testing for Huntington's disease: demand, attitudes, and psychological assessment. J Med Genet 1993;30:549-56.
24. Quaid KA, Morris M. Reluctance to undergo predictive testing: the case of Huntington disease. Am J Med Genet 1993;45:41-5.
25. Decruyenaere M, Evers-Kiebooms G, Van den Berghe H. Perception of predictive testing for Huntington's disease by young women: preferring uncertainty to certainty? J Med Genet 1993;30:557-61.
26. Elkins TE, Stovall TG, Wilroy S, et al. Attitudes of mothers of children with Down syndrome concerning amniocentesis, abortion, and prenatal genetic counseling techniques. Obstet Gynecol 1986;68:181-4.