-
1
-
-
84919573117
-
Nucleoside phosphorylase deficiency in a child with severly defective T-cell immunity and normal B-cell immunity
-
Giblett, E. R., Ammann, A. J., Wara, D. W., Sandman, R. & Diamond, L. K. (1975) Nucleoside phosphorylase deficiency in a child with severly defective T-cell immunity and normal B-cell immunity, Lancet 1, 1010-1013.
-
(1975)
Lancet
, vol.1
, pp. 1010-1013
-
-
Giblett, E.R.1
Ammann, A.J.2
Wara, D.W.3
Sandman, R.4
Diamond, L.K.5
-
2
-
-
0018244421
-
Immunological aberrations in purine nucleoside deficiency
-
Ammann, A. J. (1978) Immunological aberrations in purine nucleoside deficiency, CIBA Found. Symp. 68, 55-75.
-
(1978)
CIBA Found. Symp.
, vol.68
, pp. 55-75
-
-
Ammann, A.J.1
-
3
-
-
0020073932
-
Inhibitors of purine nucleoside phosphorylase C(8) and C(5′) substitutions
-
Stoeckler, J. D., Cambor, C., Kuhns, V., Chu, S.-H. & Parks, R. E. Jr (1982) Inhibitors of purine nucleoside phosphorylase C(8) and C(5′) substitutions, Biochem. Pharmacol. 31, 163-171.
-
(1982)
Biochem. Pharmacol.
, vol.31
, pp. 163-171
-
-
Stoeckler, J.D.1
Cambor, C.2
Kuhns, V.3
Chu, S.-H.4
Parks Jr., R.E.5
-
4
-
-
0022978888
-
Design of purine nucleoside phosphorylase inhibitors
-
Stoeckler, J. D., Ealick, S. E., Bugg, C. E. & Parks, R. E. Jr (1986) Design of purine nucleoside phosphorylase inhibitors, Fed. Proc. 45, 2773-2778.
-
(1986)
Fed. Proc.
, vol.45
, pp. 2773-2778
-
-
Stoeckler, J.D.1
Ealick, S.E.2
Bugg, C.E.3
Parks Jr., R.E.4
-
5
-
-
0022619535
-
Potentation of 2′-deoxyguanosine cytotoxicity by a novel inhibitor of purine nueleoside phosphorylase, 8-amino-9-benzyl-guanine
-
Shewach, D. S., Chern, J.-W., Pillote, K. E., Townsend, L. B. & Daddona, P. E. (1986) Potentation of 2′-deoxyguanosine cytotoxicity by a novel inhibitor of purine nueleoside phosphorylase, 8-amino-9-benzyl-guanine, Cancer Res. 46, 519-523.
-
(1986)
Cancer Res.
, vol.46
, pp. 519-523
-
-
Shewach, D.S.1
Chern, J.-W.2
Pillote, K.E.3
Townsend, L.B.4
Daddona, P.E.5
-
6
-
-
0025755768
-
Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase
-
Bzowska, A., Kulikowska, H., Shugar, D., Bing-yi, C., Lindborg, B. & Johansson, N. G. (1991) Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase, Biochem. Pharmacol. 41, 1791-1803.
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 1791-1803
-
-
Bzowska, A.1
Kulikowska, H.2
Shugar, D.3
Bing-yi, C.4
Lindborg, B.5
Johansson, N.G.6
-
7
-
-
0026015330
-
Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase
-
Dempcy, R. O. & Skibo, E. B. (1991) Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase, Biochemistry 30, 8480-8487.
-
(1991)
Biochemistry
, vol.30
, pp. 8480-8487
-
-
Dempcy, R.O.1
Skibo, E.B.2
-
8
-
-
1842401414
-
Design of purine nucleoside phosphorylase inhbitors using X-ray crystallography
-
Bugg, C. E. & Ealick, S. E., eds Springer-Verlag. New York
-
Ealick, S. E., Babu, Y. S., Narayana, S. V. L., Cook, W. J. & Bugg, C. E. (1990) Design of purine nucleoside phosphorylase inhbitors using X-ray crystallography, in Crystallographic and modelling methods in molecular design (Bugg, C. E. & Ealick, S. E., eds) pp. 43-55, Springer-Verlag. New York.
-
(1990)
Crystallographic and Modelling Methods in Molecular Design
, pp. 43-55
-
-
Ealick, S.E.1
Babu, Y.S.2
Narayana, S.V.L.3
Cook, W.J.4
Bugg, C.E.5
-
9
-
-
0026673266
-
Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, Cl-972 and PD 141955
-
Gilbertsen, R. B., Josula, U., Sircar, J. C., Dong, M. K., Wu, W.-S., Wilbrun, D. J. & Conroy, M. C. (1992) Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, Cl-972 and PD 141955, Biochem. Prarmacol, 44, 996-999.
-
(1992)
Biochem. Prarmacol
, vol.44
, pp. 996-999
-
-
Gilbertsen, R.B.1
Josula, U.2
Sircar, J.C.3
Dong, M.K.4
Wu, W.-S.5
Wilbrun, D.J.6
Conroy, M.C.7
-
10
-
-
0026349524
-
Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors
-
Ealick, S. E., Babu, Y. S., Bugg, C. E., Erion, M. D., Guida, W. C., Montgomery, J. A. & Secrist, J. A. III (1991) Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors, Proc. Natl Acad. Sci. USA 88, 11540-11544.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 11540-11544
-
-
Ealick, S.E.1
Babu, Y.S.2
Bugg, C.E.3
Erion, M.D.4
Guida, W.C.5
Montgomery, J.A.6
Secrist III, J.A.7
-
11
-
-
0025236747
-
Nucleotide analogue inhibitors of purine nucleoside phosphorylase
-
Krenitsky, T. A., Tuttle, J. V., Miller, W. H., Moorman, A. R., Orr. G. F. & Beauchamp, L.(1990) Nucleotide analogue inhibitors of purine nucleoside phosphorylase, J. Biol. Chem. 265, 3066-3069.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 3066-3069
-
-
Krenitsky, T.A.1
Tuttle, J.V.2
Miller, W.H.3
Moorman, A.R.4
Orr, G.F.5
Beauchamp, L.6
-
12
-
-
0001157528
-
Purine nucleoside phosphorylase: A target for chemotherapy
-
Glazer, R. I., ed. CRC Press Inc., Boca Raton
-
Stoeckler, J. D. (1984) Purine nucleoside phosphorylase: a target for chemotherapy, in Develoments in cancer chemotherapy (Glazer, R. I., ed.) pp. 35-60, CRC Press Inc., Boca Raton.
-
(1984)
Develoments in Cancer Chemotherapy
, pp. 35-60
-
-
Stoeckler, J.D.1
-
13
-
-
0027399142
-
Purine nucleoside phosphorylase: A target for drug design
-
Montgomery, J. A. (1993) Purine nucleoside phosphorylase: a target for drug design, Med. Res. Rev. 13, 209-228.
-
(1993)
Med. Res. Rev.
, vol.13
, pp. 209-228
-
-
Montgomery, J.A.1
-
14
-
-
0023952120
-
Purine nucleoside phosphorylase: Structure-activity relationships for substrate and inhibitor properties of N-1, N-7 and C-8-substituted analogues; differentiation of mammalian and bacterial enzymes with N-1 methylinosine and guanosine
-
Bzowska, A., Kulikowska, E., Darzynkiewicz, E. & Shugar, D. (1988) Purine nucleoside phosphorylase: structure-activity relationships for substrate and inhibitor properties of N-1, N-7 and C-8-substituted analogues; differentiation of mammalian and bacterial enzymes with N-1 methylinosine and guanosine. J. Biol. Chem. 263, 9212-9217.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 9212-9217
-
-
Bzowska, A.1
Kulikowska, E.2
Darzynkiewicz, E.3
Shugar, D.4
-
15
-
-
0027655164
-
Linear free energy relationships for N(7)-substituted guanosines as substrates of calf spleen purine nucleoside phosphorylse. Possible role of N(7)-protonation as an intermediary in phosphorolysis
-
Bzowska, A., Kulikowska, E. & Shugar, D. (1993) Linear free energy relationships for N(7)-substituted guanosines as substrates of calf spleen purine nucleoside phosphorylse. Possible role of N(7)-protonation as an intermediary in phosphorolysis, Z. Naturforsch. Sect. C J. Biosci. 48, 803-811.
-
(1993)
Z. Naturforsch. Sect. C J. Biosci.
, vol.48
, pp. 803-811
-
-
Bzowska, A.1
Kulikowska, E.2
Shugar, D.3
-
16
-
-
0025021597
-
Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 Å resolution
-
Ealick, S. E., Rule, S. A., Carter, D. C., Greenhough, T. J., Babu, Y. S., Cook, W. J., Habash, J., Halliwell, J. R., Stoeckler, J. D., Parks, R. E. Jr, Chen, S. F. & Bugg, C. E. (1990) Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 Å resolution, J. Biol. Chem. 265, 1812-1820.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 1812-1820
-
-
Ealick, S.E.1
Rule, S.A.2
Carter, D.C.3
Greenhough, T.J.4
Babu, Y.S.5
Cook, W.J.6
Habash, J.7
Halliwell, J.R.8
Stoeckler, J.D.9
Parks Jr., R.E.10
Chen, S.F.11
Bugg, C.E.12
-
17
-
-
0026705348
-
Purine nucleoside phosphorylase. Kinetic mechanism of the enzyine form calf spleen
-
Porter, D. J. T. (1992) Purine nucleoside phosphorylase. Kinetic mechanism of the enzyine form calf spleen, J. Biol. Chem. 267, 7342-7351.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7342-7351
-
-
Porter, D.J.T.1
-
18
-
-
0026690264
-
Purine nucleoside phosphorylase. Inosine hydrolysis, tight binding of the hypoxanthine intermediate, and third-the-sites reactivity
-
Kline, P. C. & Schramm, V. L. (1992) Purine nucleoside phosphorylase. Inosine hydrolysis, tight binding of the hypoxanthine intermediate, and third-the-sites reactivity, Biochemistry 31, 5964-5973.
-
(1992)
Biochemistry
, vol.31
, pp. 5964-5973
-
-
Kline, P.C.1
Schramm, V.L.2
-
19
-
-
0029015603
-
Calf spleen purine nucleoside phosphorylase: Purification, sequence and crystal structure of its complex with N(7)-acycloguanosine inhibitor
-
Bzowska, A., Luic, M., Schroeder, W., Shugar, D., Saenger, W. & Koellner, G. (1995) Calf spleen purine nucleoside phosphorylase: purification, sequence and crystal structure of its complex with N(7)-acycloguanosine inhibitor. FEBS Lett. 367, 214-218.
-
(1995)
FEBS Lett.
, vol.367
, pp. 214-218
-
-
Bzowska, A.1
Luic, M.2
Schroeder, W.3
Shugar, D.4
Saenger, W.5
Koellner, G.6
-
20
-
-
0025069455
-
Properties of purine nucleoside phosphorylase (PNP) of mammalian and bacterial origin
-
Bzowska, A., Kulikowska, E. & Shugar, D. (1990) Properties of purine nucleoside phosphorylase (PNP) of mammalian and bacterial origin. Z. Naturforsch, Sect. C J. Biosci. 45, 59-70.
-
(1990)
Z. Naturforsch, Sect. C J. Biosci.
, vol.45
, pp. 59-70
-
-
Bzowska, A.1
Kulikowska, E.2
Shugar, D.3
-
21
-
-
0026504301
-
Formyscins A and B and some analogues: Selective inhibitors of bacterial (E. coli) purine nucleoside phosphorylase
-
Bzowska, A., Kulikowska, E. & Shugar, D. (1992) Formyscins A and B and some analogues: selective inhibitors of bacterial (E. coli) purine nucleoside phosphorylase. Biochem. Biophys. Acta 1120, 239-247.
-
(1992)
Biochem. Biophys. Acta
, vol.1120
, pp. 239-247
-
-
Bzowska, A.1
Kulikowska, E.2
Shugar, D.3
-
22
-
-
0028803254
-
2-Chloro-2′-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhbitors of Escherichia coli purine-nucleoside phosphorylase
-
Bzowska, A. & Kazimierczuk, Z. (1995) 2-Chloro-2′-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhbitors of Escherichia coli purine-nucleoside phosphorylase, Eur. J. Biochem. 233, 886-890.
-
(1995)
Eur. J. Biochem.
, vol.233
, pp. 886-890
-
-
Bzowska, A.1
Kazimierczuk, Z.2
-
23
-
-
0027414454
-
Biotransformation of the antiviral agent 1,3,4-thiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite
-
Ehlhardt, W. J., Wheeler, W. J., Breau, A. P., Chay, S. H. & Birch. G. M. (1993) Biotransformation of the antiviral agent 1,3,4-thiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite. Drug metab. dispas. 21, 162-170.
-
(1993)
Drug Metab. Dispas.
, vol.21
, pp. 162-170
-
-
Ehlhardt, W.J.1
Wheeler, W.J.2
Breau, A.P.3
Chay, S.H.4
Birch, G.M.5
-
24
-
-
0022979207
-
Properties of two unusual, and fluorescent substrates of purine nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine
-
Kulikowska, E., Bzowska, A., Wierzchowski, J. & Shugar, D. (1986) Properties of two unusual, and fluorescent substrates of purine nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine, Biochim. Biophys. Acta 874, 355-363.
-
(1986)
Biochim. Biophys. Acta
, vol.874
, pp. 355-363
-
-
Kulikowska, E.1
Bzowska, A.2
Wierzchowski, J.3
Shugar, D.4
-
25
-
-
0028040552
-
Purine nucleoside phosphorylase: Inhibition by purine N(7)- and N(9)-acsclonucleosides; and substrate properties of 7-(β-D-ribofuranosyl)guanine and 7-(β-D-ribofuranosyl)hypoxanthine
-
Bzowska, A., Ananiev, A. V., Ramzaeva, N., Alksins, H., Maurins, J. A., Kulikowska, E. & Shugar, D. (1994) Purine nucleoside phosphorylase: inhibition by purine N(7)- and N(9)-acsclonucleosides; and substrate properties of 7-(β-D-ribofuranosyl)guanine and 7-(β-D-ribofuranosyl)hypoxanthine, Biochem. Pharinacol. 48, 937-947.
-
(1994)
Biochem. Pharinacol
, vol.48
, pp. 937-947
-
-
Bzowska, A.1
Ananiev, A.V.2
Ramzaeva, N.3
Alksins, H.4
Maurins, J.A.5
Kulikowska, E.6
Shugar, D.7
-
26
-
-
0001364731
-
Specificity of purine nucleoside phosphorylase from Escherichia Coli
-
Doskocil, J. & Holy, A. (1977) Specificity of purine nucleoside phosphorylase from Escherichia Coli. Collect. Czech. Chem. Commun. 42, 370-383.
-
(1977)
Collect. Czech. Chem. Commun.
, vol.42
, pp. 370-383
-
-
Doskocil, J.1
Holy, A.2
-
27
-
-
0024581571
-
Investigation of α-deuterium isotope effects on the purine nucleoside phosphorylase reaction by the equilibrium-perturbation technique
-
Lehikoinen, P. K., Sinnott, M. L. & Kremtsky, T. A. (1989) Investigation of α-deuterium isotope effects on the purine nucleoside phosphorylase reaction by the equilibrium-perturbation technique, Biochem. J. 257, 355-359.
-
(1989)
Biochem. J.
, vol.257
, pp. 355-359
-
-
Lehikoinen, P.K.1
Sinnott, M.L.2
Kremtsky, T.A.3
-
28
-
-
0000482179
-
Synthesis of 3-(β-D-ribofuranosyl)adenine and 3-(β-D-ribofuranosyl)adenine-5′-phosphate
-
Leonard, N. J. & Laursen, R. A. (1965) Synthesis of 3-(β-D-ribofuranosyl)adenine and 3-(β-D-ribofuranosyl)adenine-5′-phosphate. Biochemistry 4, 354-365.
-
(1965)
Biochemistry
, vol.4
, pp. 354-365
-
-
Leonard, N.J.1
Laursen, R.A.2
-
29
-
-
0014006194
-
Enzymatic and chemical deamination of 3-(β-D-ribofuranosyl)adenine
-
Wolfenden, R., Sharpless, T. K., Ragande, I. S. & Leonard, N. J. (1966) Enzymatic and chemical deamination of 3-(β-D-ribofuranosyl)adenine, J. Am. Chem. Soc. 88, 185-186.
-
(1966)
J. Am. Chem. Soc.
, vol.88
, pp. 185-186
-
-
Wolfenden, R.1
Sharpless, T.K.2
Ragande, I.S.3
Leonard, N.J.4
-
30
-
-
0001198282
-
Condensed pyrimidine systems. XXII. N-methylpurines
-
Elion, G. (1962) Condensed pyrimidine systems. XXII. N-methylpurines, J. Ory. Chem. 27, 2478 -2491.
-
(1962)
J. Ory. Chem.
, vol.27
, pp. 2478-2491
-
-
Elion, G.1
-
31
-
-
0017795561
-
Purine nucleoside phosphorylase from human erythrocytes
-
Stoeckler, J. D., Agarwal, R. P., Agarwal, K. C. & Parks, R. E. Jr (1978) Purine nucleoside phosphorylase from human erythrocytes, Methods Enzynol. 51, 530-538.
-
(1978)
Methods Enzynol.
, vol.51
, pp. 530-538
-
-
Stoeckler, J.D.1
Agarwal, R.P.2
Agarwal, K.C.3
Parks Jr., R.E.4
-
32
-
-
0003836971
-
-
Oxford University Press, London
-
Dawson, R. M. C., Elliott, D. C., Elliott, W. H. & Jones, K. M. (1969) Data for biochemical research, Oxford University Press, London.
-
(1969)
Data for Biochemical Research
-
-
Dawson, R.M.C.1
Elliott, D.C.2
Elliott, W.H.3
Jones, K.M.4
-
33
-
-
0003518480
-
-
John Wiley and Sons. New York
-
Segal, I. H. (1975) Enzyme kinetics, John Wiley and Sons. New York.
-
(1975)
Enzyme Kinetics
-
-
Segal, I.H.1
-
34
-
-
0018785387
-
Thyroid purine nucleoside phosphorylase II. Kinetic model by alternate substrate and inhibition studies
-
Carlson, J. D. & Fischer, A. G. (1979) Thyroid purine nucleoside phosphorylase II. Kinetic model by alternate substrate and inhibition studies, Biochim. Biophys. Acta 566, 259-265.
-
(1979)
Biochim. Biophys. Acta
, vol.566
, pp. 259-265
-
-
Carlson, J.D.1
Fischer, A.G.2
-
35
-
-
0027729453
-
Purine nucleoside phosphorylase: Catalytic mechanism and transition state analysis of the arsenolysis reaction
-
Kline. P. C. & Schramm, V. L. (1993) Purine nucleoside phosphorylase: catalytic mechanism and transition state analysis of the arsenolysis reaction. Biochemistry 32, 13212-13219.
-
(1993)
Biochemistry
, vol.32
, pp. 13212-13219
-
-
Kline, P.C.1
Schramm, V.L.2
-
36
-
-
0014961477
-
Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides
-
Zoltewicz, J. A., Clark, D. F., Sharpless, T. W. & Grahe, G. (1970) Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides. J. Am. Chem. Soc. 92, 1741-1750.
-
(1970)
J. Am. Chem. Soc.
, vol.92
, pp. 1741-1750
-
-
Zoltewicz, J.A.1
Clark, D.F.2
Sharpless, T.W.3
Grahe, G.4
-
37
-
-
0022557402
-
Relatives of Watson-Crick DNA, RNA cross sections
-
Leonard, N. J., Cruickshank, K. A., Groziak, M. P., Clauson, G. L. & Dewadas, B. (1986) Relatives of Watson-Crick DNA, RNA cross sections, Ann. N. Y. Acad. Sci. 471, 255-265.
-
(1986)
Ann. N. Y. Acad. Sci.
, vol.471
, pp. 255-265
-
-
Leonard, N.J.1
Cruickshank, K.A.2
Groziak, M.P.3
Clauson, G.L.4
Dewadas, B.5
-
38
-
-
0024287033
-
Structure of 3-isoadenosine
-
Kumar, S., Wilson, S. R. & Leonard, N. J. (1988) Structure of 3-isoadenosine. Acta Crystallogr. C44, 508-510.
-
(1988)
Acta Crystallogr.
, vol.C44
, pp. 508-510
-
-
Kumar, S.1
Wilson, S.R.2
Leonard, N.J.3
-
39
-
-
0000958543
-
Tautonierism of purines and pyrimidines, their nucleosides and various analogues
-
Springer-Verlag, Heidelberg
-
Shugar, D. & Psoda, A. (1990). Tautonierism of purines and pyrimidines, their nucleosides and various analogues, in Landolt-Bornstein Encyklopedie, vol. VII/Id. pp. 308-348. Springer-Verlag, Heidelberg.
-
(1990)
Landolt-Bornstein Encyklopedie
, vol.7
, Issue.1 D
, pp. 308-348
-
-
Shugar, D.1
Psoda, A.2
-
40
-
-
0026632378
-
Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues
-
Woo, P. W. K., Kostlan, C. R., Sircar, J. C., Dong, M. K. & Gilbertsen, R. B. (1992) Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues, J. Med. Chem. 35, 1451-1457.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 1451-1457
-
-
Woo, P.W.K.1
Kostlan, C.R.2
Sircar, J.C.3
Dong, M.K.4
Gilbertsen, R.B.5
-
41
-
-
0029024462
-
Mutagenesis and Laue structures of enzyme intermediates: Isocitrate dehydrogenase
-
Bolduc, J. M., Dyer, D. H., Scott, W. G., Singer, P., Sweet, R. W., Koshland, D. K. & Stoddard, B. L. (1995) Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase, Science 268, 1312-1318.
-
(1995)
Science
, vol.268
, pp. 1312-1318
-
-
Bolduc, J.M.1
Dyer, D.H.2
Scott, W.G.3
Singer, P.4
Sweet, R.W.5
Koshland, D.K.6
Stoddard, B.L.7
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