Synergy between T cell receptor β gene polymorphism and HLA-DR4 in susceptibility to rheumatoid arthritis

Arthritis and Rheumatism

Volumn 39, Issue 6, 1996, Pages 931-937

  Mu, Hua ^a,b   Charmley, Patrick ^c,d   King, Mary Claire ^b,e   Criswell, Lindsey A ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c BENAROYA RESEARCH INSTITUTE   (United States)

^d Darwin Molecular Corporation   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Division of Rheumatology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR4 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; DNA SEQUENCE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HLA TYPING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ARTHRITIS, RHEUMATOID; BASE SEQUENCE; DISEASE SUSCEPTIBILITY; FEMALE; GENOTYPE; HLA-DR4 ANTIGEN; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0030014978     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780390609     Document Type: Article

References (28)

1. Ollier W, Thompson W: Population genetics of rheumatoid arthritis. Rheum Dis Clin North Am 18:741-759, 1992
2. Weyand CM, Goronzy JJ: Mapping of allospecific T-cell recognition sites encoded by the HLA-DR4 β1-chain. Hum Immunol 24:133-143, 1989
3. Winchester R, Dwyer E, Rose S: The genetic basis of rheumatoid arthritis: the shared epitope hypothesis. Rheum Dis Clin North Am 18:761-783, 1992
4. Deighton CM, Walker DJ, Griffith ID, Roberts DF: The contribution of HLA to rheumatoid arthritis. Clin Genet 36:178-182, 1989.
5. Wordsworth BP, Bell JI: Polygenic susceptibility in rheumatoid arthritis. Ann Rheum Dis 50:343-346, 1991
6. Mu H, Criswell LA, King MC: Allelic variation of T cell receptor Vβ6.7 gene is associated with HLA-DR4+ RA (abstract). Arthritis Rheum 37 (suppl 9):S277, 1994
7. Gomolka M, Menninger H, Saal JE, Lemmel EM, Albert ED, Niwa O, Epplen JT, Epplen C: Immunoprinting: various genes are associated with increased risk to develop rheumatoid arthritis in different groups of adult patients. J Mol Med 73:19-29, 1995
8. McDermott M, Kastner DL, Holloman JD, Schmidt-Wolf G, Lundberg AS, Sinha AA, Hsu C, Cashin P, Molloy MG, Mulcahy B, O'Gara F, McConnell FI, Adams C, Khan MA, Wolfe F, Rubin LA, Clegg DO, Husebye D, Amos CI, Ward RH, McDevitt HO: The role of T cell receptor β chain genes in susceptibility to rheumatoid arthritis. Arthritis Rheum 38:91-95, 1995
9. Kay RA, Hutchings CJ, Ollier WER: A subset of Sjögren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus. Hum Immunol 42:328-330, 1995
10. Maksymowych WP, Gabriel CA, Luyrink L, Melin-Aldana H, Elma M, Giannini EH, Lovell DJ, van Derckhove C, Leiden J, Choi E, Glass DN: Polymorphism in a T-cell receptor variable gene associated with susceptibility to a juvenile rheumatoid arthritis subset. Immunogenetics 35:257-262, 1992
11. Charmley P, Nepom BB, Concannon P: HLA and T cell receptor β-chain DNA polymorphisms identify a distinct subset of patients with pauciarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum 37:695-701, 1994
12. Yelin EH, Henke CJ, Kramer JS, Nevitt MC, Shearn M, Epstein WV: A comparison of the treatment of rheumatoid arthritis in health maintenance organizations and fee-for-service practice. N Engl J Med 312:962-967, 1985
13. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ: The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271-1277, 1982
14. Bidwell JL, Bignon JD: DNA-RFLP methods and interpretation scheme for HLA-DR and DQ typing. Eur J Immunogen 18:5-22, 1991
15. Peterdorf EW, Smith AG, Mickelson EM, Martin PJ, Hansen JA: Ten HLA-DR4 alleles defined by sequence polymorphisms within the DRB1 first domain. Immunogenetics 33:267-275, 1991
16. Ota M, Seki T, Fukushima H, Tsuji K, Inoko H: HLA-DRB1 genotyping by modified PCR-RFLP method combined with group-specific primers. Tissue Antigens 39:187-202, 1992
17. Li Y, Szabo P, Robinson MA, Dong B, Posnett D: Allelic variations in the human T cell receptor Vβ6.7 gene products. J Exp Med 171:221-230, 1990
18. Robinson MA: Allelic sequence variations in the hypervariable region of a TCR chain: correlation with restriction fragment length polymorphism in human families and populations. Proc Natl Acad Sci U S A 86:9422-9426, 1989
19. Cornelis F, Pile K, Loveridge J, Moss P, Harding R, Julier C, Bell J: Systematic study of human αβ T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes. Eur J Immunol 23:1277-1283, 1993
20. Li Y, Szabo P, Posnett D: The genomic structure of human Vβ6 T cell antigen receptor genes. J Exp Med 174:1537-1547, 1991
21. Charmley P, Concannon P: PCR-based genotyping and haplotype analysis of human TCRBV gene segment polymorphisms. Immunogenetics 42:254-261, 1995
22. Nickerson DA, Whitehurst C, Boysen C, Charmley P, Kaiser R, Hood L: Identification of clusters of biallelic polymorphic sequence-tagged sites (pSTSs) that generate highly informative and automatable markers for genetic linkage mapping. Genomics 12:377-387, 1992
23. Newton CR, Graham A, Heptinstall LE, Powell SL, Summers C, Kalsheker N, Smith JC, Markham AF: Analysis of any point mutation in DNA: the amplification refractory mutation system (ARMS). Nucleic Acids Res 17:2503-2516, 1989
24. Lewontin RC: The interaction of selection and linkage. I. General considerations; heterotic models. Genetics 49:49-67, 1964
25. Acha-Orbea H, Steinman L, McDevitt HO: T cell receptors in murine autoimmune diseases. Annu Rev Immunol 7:371-405, 1989
26. Funkhouser SW, Concannon P, Charmley P, Vredevoe DL, Hood L: Differences in T cell receptor restriction fragment length polymorphisms in patients with rheumatoid arthritis. Arthritis Rheum 35:465-471, 1992
27. Weyand CM, Oppitz U, Hicok K, Goronzy JJ: Selection of T cell receptor Vβ elements by HLA-DR determinants predisposing to rheumatoid arthritis. Arthritis Rheum 35:990-998, 1992
28. Kay RA, Snowden N, Hajeer AH, Boylston AW, Ollier WER: Genetic control of the human Vβ13.2 T cell repertoire: importance of allelic variation outside the coding regions of the TCRBV13S2 gene. Eur J Immunol 24:2863-2867, 1994