Scorpion venoms: Taking the sting out of lung disease

Thorax

Volumn 51, Issue 5, 1996, Pages 546-548

  Rogers, D F ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Asthma; Bronchodilator drugs; K+ channels; Nerve; agonist

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; NITRIC OXIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; THEOPHYLLINE;

ASTHMA; CHRONIC BRONCHITIS; DRUG ACTIVITY; DRUG EFFECT; HUMAN; LUNG DISEASE; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0030014777     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.51.5.546     Document Type: Short Survey

References (12)

1. Garcia ML, Galvez A, Garcia-Calvo M, King VF, Vasquez J, Kaczorowski GJ. Use of toxins to study potassium channels. J Bioenerg Biomembr 1991;23:615-46.
2. Torphy TJ. β-Adrenoceptors, cAMP and airway smooth muscle: challenges to the dogma. Trends Pharmacol Sci 1994;15:370-4.
3. Ca channels in airway smooth muscle by cAMP-dependent and independent mechanisms. J Clin Invest 1994;93:371-9.
4. Jones TR, Charette L, Garcia ML, Kaczorowski GJ. Interaction of iberiotoxin with β-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea. J Appl Physiol 1993;74:1879-84.
5. Miura M, Belvisi MG, Stretton CD, Yacoub MH, Barnes PJ. Role of potassium channels in bronchodilator responses in human airways. Am Rev Respir Dis 1992;146:132-6.
6. + channels in the modulation of cholinergic neural responses in guinea-pigs and human airways. J Physiol 1992;455:1-15.
7. Stretton CD, Miura M, Belvisi MG, Barnes PJ. Calcium-activated potassium channels mediate prejunctional inhibition of peripheral sensory nerves. Proc Natl Acad Sci USA 1992;89:1325-9.
8. Barnes PJ. Asthma as an axon reflex. Lancet 1986;i:242-5.
9. Karlsson J-A. A role for capsaicin-sensitive, tachykinin containing nerves in chronic coughing and sneezing but not in asthma: a hypothesis. Thorax 1993;48:396-400.
10. Barnes PJ. Muscarinic receptors in tht airways: recent developments. J Appl Physiol 1990;68:1777-85.
11. + channels in bovine tracheal smooth muscle cells in culture. Br J Pharmacol 1995;116:1656-60.
12. Ramnarine SI, Khawaja AM, Bryce P, Hicks PE, Barnes PJ, Rogers DF. Effects of potassium channel openers on neurogenic airway mucus secretion in the ferret. Am J Respir Crit Care Med 1995;151:A820.