The antitumor drug aclacinomycin A, which inhibits the degradation of ubiquitinated proteins, shows selectivity for the chymotrypsin-like activity of the bovine pituitary 20 S proteasome

Journal of Biological Chemistry

Volumn 271, Issue 28, 1996, Pages 16455-16459

  Figueiredo Pereira, Maria E ^a,c   Chen, Wei Er ^a   Li, Jingrong ^a   Johdo, Osamu ^b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b MERCIAN CORPORATION   (Japan)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACLARUBICIN; ANTINEOPLASTIC AGENT; CHYMOTRYPSIN; PROTEASOME; UBIQUITIN;

ARTICLE; CATALYSIS; CATTLE; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ANALYSIS; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL;

ACLARUBICIN; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CATALYSIS; CATTLE; CHYMOTRYPSIN; CYSTEINE ENDOPEPTIDASES; HYDROLYSIS; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; PITUITARY GLAND; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; UBIQUITINS;

BOS TAURUS; BOVINAE; ORYCTOLAGUS CUNICULUS;

EID: 0030014641     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.28.16455     Document Type: Article

References (43)

1. Isoe, T., Naito, M., Shirai, A., Hirai, R., and Tsuruo, T. (1992) Biochim. Biophys. Acta 1117, 131-135
2. Lupas, A., Koster, A. J., and Baumeister, W. (1994) Enzyme & Protein 47, 252-271
3. Coux, O., Nothwang, H. G., Silva Pereira, I., Recillas Targa, F., Bey, F., and Scherrer, K. (1994) Mol. & Gen. Genet. 245, 769-780
4. Kopp, F., Dahlmann, B., and Hendil, K. (1993) J. Mol. Biol. 229, 14-19
5. Löwe, J., Stock, D., Jap, B., Zwickl, F., Baumeister, W., and Huber, R. (1995) Science 268, 533-539
6. Seemüller, E., Lupas, A., Stock, D., Löwe, J., Huber, R., and Baumeister, W. (1995) Science 268, 579-582
7. Fenteany, G., Standaert, R. F., Lane, W. S., Choi, S., Corey, E. J., and Schreiber, S. L. (1995) Science 268, 726-730
8. Wilk, S., and Orlowski, M. (1980) J. Neurochem. 35, 1172-1182
9. Wilk, S., and Orlowski, M. (1983) J. Neurochem. 40, 842-849
10. Cardozo, C., Vinitisky, A., Hidalgo, M. C., Michaud, C., and Orlowski, M. (1992) Biochemistry 31, 7373-7380
11. Orlowski, M., Cardozo, C., and Michaud, C. (1993) Biochemistry 32, 1563-1572
12. Yu, B., Pereira, M. E., and Wilk, S. (1991) J. Biol. Chem. 266, 17396-17400
13. Pereira, M. E., Yu, B., and Wilk, S. (1992) Arch. Biochem. Biophys. 294, 1-8
14. Strack, P. R., Wajnberg, E. F., Waxman, L., and Fagan, J. M. (1992) Int. J. Biochem. 24, 887-895
15. Pereira, M. E., Nguyen, T., Wagner, B. J., Margolis, J. W., Yu, B., and Wilk, S. (1992) J. Biol. Chem. 267, 7949-7955
16. Figuoiredo-Pereira, M. E., Yu, B., and Wilk, S. (1994) J Biol. Chem. 269, 621-626
17. Heinmeyer, W., Kleinschmidt, J. A., Saidowsky, J., Escher, C., and Wolf, D. H. (1991) EMBO J. 10, 555-562
18. Heinmeyer, W., Gruhler, A., Mohrle, V., Mahe, Y., and Wolf, D. H. (1993) J. Biol. Chem. 268, 5115-5120
19. Hilt, W., Enenkel, C., Gruhler, A., Singer, T., and Wolf, D. H. (1993) J. Biol. Chem. 268, 3479-3486
20. Enenkel, C., Lehmann, H., Kipper, J., Guckel, R., Hilt, W., and Wolf, D. H. (1994) FEBS Lett. 341, 193-196
21. Basile, G., Aker, M., and Mortimer, R. K. (1992) Mol. Cell. Biol. 12, 3235-3246
22. Nishimura, C., Tamura, T., Akioka, H., Tokunaga, F., Tanaka, K., and Ichihara, A. (1993) FEBS Lett. 336, 462-466
23. Sato, S., and Shiratusuchi, A. (1990) Biochim. Biophys. Acta 1041, 269-272
24. Wagner, B. J., Margolis, J. W., and Yin, J. (1991) Curr. Bye Res. 10, 485-489
25. Dick, L. R., Moomaw, C. R., Pramanik, B. C., DeMartino, G. N., and Slaughter, C. A. (1992) Biochemistry 31, 7347-7355
26. Savory, P. J., and Rivett, A. J. (1993) Biochem. J. 289, 45-48
27. Rechsteiner, M., Hoffman, L., and Dubiel, W. (1993) J. Biol. Chem. 268, 6065-6068
28. Orlowski, M., and Michaud, C. (1989) Biochemistry 28, 9270-9278
29. Wilk, S., Pearce, S., and Orlowski, M. (1979) Life Sci. 24, 457-464
30. Tsubuki, S., Saito, Y., and Kawashima, S. (1994) FEBS Lett. 344, 229-233
31. Figueiredo-Pereira, M. E., Chen, W. E., Yuan, H. M., and Wilk, S. (1996) Arch. Biochem. Biophys. 317, 69-78
32. Bajkowski, A. S., and Frankfater, A. (1975) Anal. Biochem. 68, 119-127
33. Barrett, A. J., and Kirschke, H. (1981) Methods Enzymol. 80, 535-561
34. Oki, T., Kitamura, I., Matsuzawa, Y., Shibamoto, N., Ogasawara, T., Yoshimoto, A., Inui, T., Naganawa, H., Takeuchi, T., and Umezawa, H. (1979) J. Antibiol. (Tokyo) 32, 801-819
35. Figueiredo-Pereira, M. E., Banik, N., and Wilk, S. (1994) J. Neurochem. 62, 1989-1994
36. Oki, T., Takeuchi, T., Oka, S., and Umezawa, H. (1981) Recent Results Cancer Res. 76, 21-40
37. Figueiredo-Pereira, M. E., Berg, K. A., and Wilk, S. (1995) J. Neurochem. 63, 1578-1581
38. Gregori, L., Fuchs, C., Figueiredo-Pereira, M. E., VanNostrand, W. E., and Goldgaber, D. (1995) J. Biol. Chem. 270, 19702-19708
39. Giulivi, C., Pacifici, R. E., and Davies, J. A. (1994) Arch. Biochem. Biophys. 311, 329-341
40. Segel, I. H. (1975) Enzyme Kinetics, pp. 125-130, John Wiley & Sons, Inc., New York
41. Yang, D., and Wang, A. H.-J. (1994) Biochemistry 33, 6595-6604
42. Goldberg, A. L., Stein, R., and Adams, J. (1995) Chem. & Biol. 2, 503-508
43. Furono, K., Goodman, M. N., and Goldberg, A. L (1990) J. Biol. Chem. 265, 8550-8557