Cardiovascular effects of the K-ATP channel blocker U-37883A and structurally related morpholinoguanidines

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 18, Issue 4, 1996, Pages 247-260

  Humphrey, S J ^a   Smith, M P ^a   Cimini, M G ^a   Buchanan, L V ^a   Gibson, J K ^a   Khan, S A ^a   Meisheri, K D ^a  

^a PFIZER INC   (United States)

Author keywords

Cardiovascular; K ATP channel; Morpholinoguanide; U 37883A

Indexed keywords

CARDIOVASCULAR AGENT; DIURETIC AGENT; GUANIDINE DERIVATIVE; N (1 ADAMANTYL) N' CYCLOHEXYL 4 MORPHOLINECARBOXAMIDINE; POTASSIUM CHANNEL BLOCKING AGENT; U 45194A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DIURESIS; DOG; DRUG EFFECT; DRUG SCREENING; FEMALE; HEART LEFT VENTRICLE VOLUME; HEART STROKE VOLUME; HEMODYNAMICS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; RAT;

ADAMANTANE; ADENOSINE TRIPHOSPHATE; ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMAL WELFARE; ANIMALS; BLOOD PRESSURE; DIURETICS; DOGS; ELECTROPHYSIOLOGY; FEMALE; GUANIDINES; HEART RATE; INJECTIONS, INTRAVENOUS; MALE; MESENTERIC ARTERIES; MORPHOLINES; MYOCARDIAL CONTRACTION; PAPILLARY MUSCLES; PINACIDIL; POTASSIUM CHANNELS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; STROKE VOLUME; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR RESISTANCE; VASODILATOR AGENTS; VENTRICULAR FUNCTION, LEFT;

EID: 0030014372     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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