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Volumn 17, Issue 6, 1996, Pages 1259-1265

Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BRYOSTATIN 1; CELL MARKER; FILAGGRIN; ISOENZYME; MESSENGER RNA; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; STAUROSPORINE;

EID: 0030013883     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.6.1259     Document Type: Article
Times cited : (21)

References (39)
  • 2
    • 0023199866 scopus 로고
    • Response of carcinogen-altered mouse epidermal cells to phorbol ester tumor promoters and calcium
    • Hennings,H., Michael,D., Lichti,U. and Yuspa,S.H. (1987) Response of carcinogen-altered mouse epidermal cells to phorbol ester tumor promoters and calcium. J. Invest. Dermatol., 88, 60-65.
    • (1987) J. Invest. Dermatol. , vol.88 , pp. 60-65
    • Hennings, H.1    Michael, D.2    Lichti, U.3    Yuspa, S.H.4
  • 3
    • 0019720955 scopus 로고
    • Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis
    • Yuspa,S.H. and Morgan,D.L. (1981) Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis. Nature (Lond.), 293, 72-74.
    • (1981) Nature (Lond.) , vol.293 , pp. 72-74
    • Yuspa, S.H.1    Morgan, D.L.2
  • 4
    • 0020080466 scopus 로고
    • Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
    • Yuspa,S.H., Ben,T., Hennings,H. and Lichti,U. (1982) Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 42, 2344-2349.
    • (1982) Cancer Res. , vol.42 , pp. 2344-2349
    • Yuspa, S.H.1    Ben, T.2    Hennings, H.3    Lichti, U.4
  • 5
    • 0020698644 scopus 로고
    • Effects of tumor promoters on the rate and commitment to terminal differentiation of subpopulations of murine keratinocytes
    • Reiners,J.J. and Slaga,T.J. (1983) Effects of tumor promoters on the rate and commitment to terminal differentiation of subpopulations of murine keratinocytes. Cell, 32, 247-255.
    • (1983) Cell , vol.32 , pp. 247-255
    • Reiners, J.J.1    Slaga, T.J.2
  • 6
    • 0026627746 scopus 로고
    • Transcripts encoding protein kinase C alpha, delta, epsilon, zeta, and eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells
    • Dlugosz,A.A., Mischak,H., Mushinski,J.F. and Yuspa,S.H. (1992) Transcripts encoding protein kinase C alpha, delta, epsilon, zeta, and eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells. Mol. Carcinogenesis, 5, 286-292.
    • (1992) Mol. Carcinogenesis , vol.5 , pp. 286-292
    • Dlugosz, A.A.1    Mischak, H.2    Mushinski, J.F.3    Yuspa, S.H.4
  • 7
    • 0027332733 scopus 로고
    • Ha gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C δ
    • Ha gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C δ. J. Biol. Chem., 268, 26079-26081.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26079-26081
    • Denning, M.F.1    Dlugosz, A.A.2    Howett, M.K.3    Yuspa, S.H.4
  • 9
    • 0027057581 scopus 로고
    • Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: Relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype
    • Lee,E., Punnonen,K., Cheng,C., Glick,A., Dlugosz,A. and Yuspa,S.H. (1992) Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype. Carcinogenesis, 13, 2367-2373.
    • (1992) Carcinogenesis , vol.13 , pp. 2367-2373
    • Lee, E.1    Punnonen, K.2    Cheng, C.3    Glick, A.4    Dlugosz, A.5    Yuspa, S.H.6
  • 10
    • 0023748902 scopus 로고
    • Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells
    • Sako,T., Tauber,A.I., Jeng,A.Y., Yuspa,S.H. and Blumberg,P.M. (1988) Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells. Cancer Res., 48, 4646-4650.
    • (1988) Cancer Res. , vol.48 , pp. 4646-4650
    • Sako, T.1    Tauber, A.I.2    Jeng, A.Y.3    Yuspa, S.H.4    Blumberg, P.M.5
  • 11
    • 0025941535 scopus 로고
    • Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro
    • Dlugosz,A.A. and Yuspa,S.H. (1991) Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro. Cancer Res., 51, 4677-4684.
    • (1991) Cancer Res. , vol.51 , pp. 4677-4684
    • Dlugosz, A.A.1    Yuspa, S.H.2
  • 12
    • 0028351556 scopus 로고
    • The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis - Thirty-third G.H.A. Clowes Memorial Award Lecture
    • Yuspa,S.H. (1994) The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis - Thirty-third G.H.A. Clowes Memorial Award Lecture. Cancer Res., 54, 1178-1189.
    • (1994) Cancer Res. , vol.54 , pp. 1178-1189
    • Yuspa, S.H.1
  • 13
    • 0027243119 scopus 로고
    • Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine. an inducer of squamous differentiation
    • Strickland,J.E., Dlugosz,A.A., Hennings,H. and Yuspa,S.H. (1993) Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine. an inducer of squamous differentiation. Carcinogenesis, 14, 205-209.
    • (1993) Carcinogenesis , vol.14 , pp. 205-209
    • Strickland, J.E.1    Dlugosz, A.A.2    Hennings, H.3    Yuspa, S.H.4
  • 15
    • 0024394417 scopus 로고
    • Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
    • Ruegg,U.T. and Burgess,G.M. (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol. Sci., 10, 218-220.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 218-220
    • Ruegg, U.T.1    Burgess, G.M.2
  • 17
    • 0018865014 scopus 로고
    • Calcium regulation of growth and differentiation of mouse epidermal cells in culture
    • Hennings,H., Michael,D., Cheng,C., Steinert,P., Holbrook,K. and Yuspa,S.H. (1980) Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell, 19, 245-254.
    • (1980) Cell , vol.19 , pp. 245-254
    • Hennings, H.1    Michael, D.2    Cheng, C.3    Steinert, P.4    Holbrook, K.5    Yuspa, S.H.6
  • 18
    • 0025995656 scopus 로고
    • Quantitation of cross-linked protein: An alternative to counting cornified envelopes as an index of keratinocyte differentiation
    • Hough-Monroe,L. and Milslone,L.M. (1991) Quantitation of cross-linked protein: an alternative to counting cornified envelopes as an index of keratinocyte differentiation. Anal. Biochem., 199, 25-28.
    • (1991) Anal. Biochem. , vol.199 , pp. 25-28
    • Hough-Monroe, L.1    Milslone, L.M.2
  • 19
    • 0024454035 scopus 로고
    • Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro
    • Yuspa,S.H., Kilkenny,A.E., Steinert,P.M. and Roop,D.R. (1989) Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J. Cell Biol., 109, 1207-1217.
    • (1989) J. Cell Biol. , vol.109 , pp. 1207-1217
    • Yuspa, S.H.1    Kilkenny, A.E.2    Steinert, P.M.3    Roop, D.R.4
  • 21
    • 0025339380 scopus 로고
    • Identification of a major keratinocyte cell envelope protein, loricrin
    • Mehrel,T., Hohl,D., Rothnagel,J.A. et al. (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell, 61, 1103-1112.
    • (1990) Cell , vol.61 , pp. 1103-1112
    • Mehrel, T.1    Hohl, D.2    Rothnagel, J.A.3
  • 23
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate - Phenol - chloroform extraction
    • Chomezynski,P. and Sacchi,N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate - phenol - chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomezynski, P.1    Sacchi, N.2
  • 24
    • 0028231262 scopus 로고
    • k) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium
    • k) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium. J. Invest. Dermatol., 102, 409-414.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 409-414
    • Dlugosz, A.A.1    Yuspa, S.H.2
  • 26
    • 0027302408 scopus 로고
    • The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse
    • Kim,I.G., Gorman,J.J., Park,S.C., Chung,S.I. and Steinert,P.M. (1993) The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse. J. Biol. Chem., 268, 12682-12690.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12682-12690
    • Kim, I.G.1    Gorman, J.J.2    Park, S.C.3    Chung, S.I.4    Steinert, P.M.5
  • 27
    • 0029997555 scopus 로고    scopus 로고
    • Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes
    • Stanwell,C., Denning,M.F., Rutberg,S.E., Cheng,C., Yuspa,S.H. and Dlugosz,A.A. (1996) Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes. J. Invest. Dermatol., 106, 482-489.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 482-489
    • Stanwell, C.1    Denning, M.F.2    Rutberg, S.E.3    Cheng, C.4    Yuspa, S.H.5    Dlugosz, A.A.6
  • 29
    • 0028293261 scopus 로고
    • Staurosporine, a non-specific PKC inhibitor, induces keratinocyte differentiation and raises intracellular calcium, but Ro31-8220. a specific inhibitor, does not
    • Jones,K.T. and Sharpe,G.R. (1994) Staurosporine, a non-specific PKC inhibitor, induces keratinocyte differentiation and raises intracellular calcium, but Ro31-8220. a specific inhibitor, does not. J. Cell Physiol., 159, 324-330.
    • (1994) J. Cell Physiol. , vol.159 , pp. 324-330
    • Jones, K.T.1    Sharpe, G.R.2
  • 30
    • 0026674533 scopus 로고
    • Protein kinase C-dependent and -independent actions of a potent protein kinase C inhibitor, staurosporine
    • Yamamoto,S., Jiang,H., Nishikawa,K., Ishihara,M., Wang,J.C. and Kato,R. (1992) Protein kinase C-dependent and -independent actions of a potent protein kinase C inhibitor, staurosporine. Eur. J. Pharmacol., 227, 113-122.
    • (1992) Eur. J. Pharmacol. , vol.227 , pp. 113-122
    • Yamamoto, S.1    Jiang, H.2    Nishikawa, K.3    Ishihara, M.4    Wang, J.C.5    Kato, R.6
  • 31
  • 32
    • 0028126624 scopus 로고
    • Bryostatin 1 protects PKCδ from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester induced differentiation
    • Szallasi,Z., Denning,M.F., Smith,C.B., Dlugosz.A.A., Yuspa,S.H., Pettit,G.R. and Blumberg,P.M. (1994) Bryostatin 1 protects PKCδ from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester induced differentiation. Mol. Pharmacol., 46, 840-850.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 840-850
    • Szallasi, Z.1    Denning, M.F.2    Smith, C.B.3    Dlugosz, A.A.4    Yuspa, S.H.5    Pettit, G.R.6    Blumberg, P.M.7
  • 34
    • 0028953612 scopus 로고
    • Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation
    • Courage,C., Budworth,J. and Gescher,A. (1995) Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation. Br. J. Cancer, 71, 697-704.
    • (1995) Br. J. Cancer , vol.71 , pp. 697-704
    • Courage, C.1    Budworth, J.2    Gescher, A.3
  • 35
    • 0028092237 scopus 로고
    • Selective involvement of protein kinase C isozymes in differentiation and neoplastic transformation
    • Goodnight,J., Mischak,H. and Mushinski,J.F. (1994) Selective involvement of protein kinase C isozymes in differentiation and neoplastic transformation. Adv. Cancer Res., 64, 159-209.
    • (1994) Adv. Cancer Res. , vol.64 , pp. 159-209
    • Goodnight, J.1    Mischak, H.2    Mushinski, J.F.3
  • 36
    • 0028172015 scopus 로고
    • Staurosporine induces tyrosine phosphorylation of a 145 kDa protein but does not activate gp 140trk in PC12 cells
    • Rasouly,D. and Lazarovici,P. (1994) Staurosporine induces tyrosine phosphorylation of a 145 kDa protein but does not activate gp 140trk in PC12 cells. Eur. J. Pharmacol., 269, 255-264.
    • (1994) Eur. J. Pharmacol. , vol.269 , pp. 255-264
    • Rasouly, D.1    Lazarovici, P.2
  • 37
    • 0025819369 scopus 로고
    • Staurosporine both activates and inhibits serine/threonine kinases in human platelets
    • Kocher,M. and Clemetson,K.J. (1991) Staurosporine both activates and inhibits serine/threonine kinases in human platelets. Biochem. J., 275, 301-306.
    • (1991) Biochem. J. , vol.275 , pp. 301-306
    • Kocher, M.1    Clemetson, K.J.2
  • 38
    • 0026661523 scopus 로고
    • Effect of Staurosporine on fMet-Leu-Phe-stimulated human neutrophils: Dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium
    • Nigam,S., Muller,S. and Walzog,B. (1992) Effect of Staurosporine on fMet-Leu-Phe-stimulated human neutrophils: dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium. Biochim. Biophys. Acta, 1135, 301-308.
    • (1992) Biochim. Biophys. Acta , vol.1135 , pp. 301-308
    • Nigam, S.1    Muller, S.2    Walzog, B.3
  • 39
    • 0028300956 scopus 로고
    • Staurosporine up-regulates the expression of phorbol dibutyrate binding sites in human platelets
    • Rais,S., Combadiere,C., Hakim,J. and Perianin,A. (1994) Staurosporine up-regulates the expression of phorbol dibutyrate binding sites in human platelets. Biochem. Pharmacol., 47, 1797-1804.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1797-1804
    • Rais, S.1    Combadiere, C.2    Hakim, J.3    Perianin, A.4


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