The effect of purified extract of Fagopyrum esculentum (buckwheat) on protein kinases involved in signal transduction pathways

Planta Medica

Volumn 62, Issue 2, 1996, Pages 106-110

  Samel, D ^a   Donnella Deana, A ^b   De Witte, P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

fagopyrin; Fagopyrum esculentum; inhibition; Polygonaceae; protein kinase

Indexed keywords

ADENOSINE TRIPHOSPHATE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FAGOPYRUM ESCULENTUM EXTRACT; HYPERICIN; INSULIN; INSULIN RECEPTOR; PLANT EXTRACT; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CELL LINE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG SELECTIVITY; ENZYME ACTIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PHOTOSENSITIZATION; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY;

3T3 CELLS; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE; CEREALS; ENZYME INHIBITORS; HUMANS; MICE; PERYLENE; PLANT EXTRACTS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0030013645     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-957828     Document Type: Article

References (19)

1. Shalloway, D. Shenoy, S. (1991) Advances in Cancer Research, Vol. 57, (Klein, G., Vande Waude, G. W., eds.), pp. 185-225, Academic Press, San Diego.
2. Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R., Soltoff, S. (1991) Cell 64, 281-302.
3. Hunter, T. (1989) Oncogenes and molecular origins of cancer, (Weinberg, R. A., ed.), pp. 147-173, Cold Spring Harbor Laboratory Press.
4. Levitzki, A., Gazit, A. (1995) Science 267, 1782-1787.
5. Lofts, F. J., Gullick, W. J. (1994) New molecular targets for cancer chemotherapy, (Kerr, D. J., Workman, P., eds.), pp. 45-57, CRC Press Inc.
6. Chang, C., Geahlen, R. (1992) J. Nat. Prod. 55, 1549-1560.
7. de Witte, P., Agostinis, P., Van Lint, J., Merlevede, W., Vandenheede, J. R. (1993) Biochem. Pharmacol. 46, 1929-1936.
8. Agostinis, P., Vandenbogarde, A., Donella-Daena A., Pinna, L. A., Lee, K. T., Goris, J., Merlevede, W., Vandenheede, J. R., de Witte, P. (1995) Biochem. Pharmacol. 49, 1651-1662.
9. Geise, A. C. (1980) Photochem. Photobiol. Rev. 5, 229-255.
10. Brockmann, H., Lackner, H. (1979) Tetrahedron Lett. 1575-1578.
11. Thom, D., Powell, A. J., Lloyd, C. W., Rees, D. A. (1977) Biochem. J. 168, 187-194.
12. Mercier, J. C., Maubois, J. L., Pozhonski, S., Rebadeau-Dumas, B. (1968) Bull. Soc. Chim. Biol. 50, 521-530.
13. Brockmann, H., Weber, E., Pampus, G. (1952) Liebigs Ann. Chem. 575, 53-83.
14. Brockmann, H., Weber, E., Sander, E. (1950) Naturwissenschaften 37, 43.
15. Brockmann, H. (1957) Fortschr. Chem. Org. Naturstoffe 14, 141-177.
16. Chick, H., Ellinger, P. (1941) J. Physiol. 100, 212-230.
17. Thomas, C., MacGill, R. S., Miller, G. C., Pardini, R. S. (1992) Photochem. Photobiol. 55, 47-53.
18. Dougherty, T. J., Marcus, S. L. (1992) Eur. J. Cancer, 28A, 1734-1742.
19. Ash, D., Brown, S. B. (1993) Eur. J. Cancer, 29A, 1781-1783.