Mutations within the primer binding site of the human immunodeficiency virus type 1 define sequence requirements essential for reverse transcription

Virology

Volumn 220, Issue 2, 1996, Pages 290-298

  Wakefield, John K ^a   Morrow, Casey D ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED DNA POLYMERASE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; VIRUS MUTATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030013267     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0317     Document Type: Article

References (24)

1. Baltimore, D. (1970). Viral RNA-dependent DNA polymerase. Nature (London) 226, 1209-1211.
2. Lys,3 with nucleocapsid protein and reverse transcriptase. J. Mol. Biol. 231, 185-190.
3. Coffin, J. M. (1990). Retroviridae and their replication. In "Virology" (B. N. Fields, Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. P. Monath, and B. Roizman, Ed.), 2nd ed., pp. 1437-1500. Academic Press, New York.
4. Gilboa, E, Mitra, S. W., Goff, S., and Baltimore, D. (1979). A detailed model of reverse transcription and tests of crucial aspects. Cell 18, 93-100.
5. Lys,3 (template/primer) complex. J. Mol. Biol. 247, 236-250.
6. Lys,3 modulate primer/template loop-loop interaction in the initiation complex of HIV-1 reverse transcription. J. Biol. Chem. 268, 25269-25272.
7. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clarke, A. D., Jr., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H., and Arnold, E. (1993). Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. Proc. Natl. Acad. Sci. USA 90, 6320-6324.
8. Gln,2 as a primer in an in vitro primer-utilization assay. Proc. Natl. Acad. Sci. USA 89, 9652-9656.
9. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., and Steitz, T. A. (1992). Crystal structure at 3.5A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256, 1783-1790.
10. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1982). Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
11. Pulsinelli, G. A., and Temin, H. M. (1994). High rate of mismatch extension during reverse transcription in a single round of retrovirus replication. Proc. Natl. Acad. Sci. USA 91, 9490-9494.
12. Ratner, L., Fisher, A., Jagodzinski, L. L., Mitsuya, N., Liou, R.-S., Gallo, R. C., and Wong-Staal, F. (1987). Complete nucleotide sequences of functional clones of the AIDS virus. AIDS Res. Hum. Retroviruses 3, 57-69.
13. Lys primer-binding site of human immunodeficiency virus type 1 identify essential regions for reverse transcription. J. Virol. 65, 4555-4564.
14. Sanger, F., Nicklen, S., and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
15. Shalka, A. M., and Goff, S. P. (1993). Reverse transcription. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
16. Taylor, J. M., and Hsu, T. W. (1980). Reverse transcription of avian sarcoma virus RNA into DNA might involve copying of the tRNA primer. J. Virol. 33, 531-534.
17. Temin, H. (1981). Structure, variation and synthesis of retrovirus long terminal repeat. Cell 27, 1-3.
18. Temin, H. M., and Mizutani, S. (1970). RNA-directed DNA polymerase in virions of Rous sarcoma virus. Nature 226, 1211-1213.
19. Varmus, H. (1982). Form and function of retroviral proviruses. Science 216, 812-820.
20. His. J. Virol. 70, 966-975.
21. Wakefield, J. K., Rhim, H., and Morrow, C. D. (1994). Minimal sequence requirements of a functional human immunodeficiency virus type 1 primer binding site. J. Virol. 68, 1605-1614.
22. Lys,3. J. Virol. 69, 6021-6029.
23. Lys,3 complexes. J. Biol. Chem. 268, 13617-13624.
24. Yu, H., and Goodman, M. F. (1992). Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J. Biol. Chem. 267, 10888-10896.