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Volumn 34, Issue 5, 1996, Pages 604-607

A simple procedure for determining the aqueous half-lives of pyrrolic metabolites of pyrrolizidine alkaloids

Author keywords

[No Author keywords available]

Indexed keywords

PYRROLIZIDINE ALKALOID;

EID: 0030012814     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(95)00169-7     Document Type: Article
Times cited : (26)

References (15)
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    • (1970) J. Path. , vol.100 , pp. 169-175
    • Butler, W.H.1    Mattocks, A.R.2    Barnes, J.M.3
  • 2
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    • Dihydropyrrolizines III. Preparation and reactions of derivatives related to pyrrolizidine alkaloids
    • Culvenor, C. C. J., Edgar, J. A., Smith, L. W. and Tweeddale, H. J. (1970) Dihydropyrrolizines III. Preparation and reactions of derivatives related to pyrrolizidine alkaloids. Aust. J. Chem. 23, 1853-1867.
    • (1970) Aust. J. Chem. , vol.23 , pp. 1853-1867
    • Culvenor, C.C.J.1    Edgar, J.A.2    Smith, L.W.3    Tweeddale, H.J.4
  • 3
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    • Detection of a reactive pyrrole in the hepatic metabolism of the pyrrolizidine alkaloid, monocrotaline
    • Glowaz, S. L., Michnika, M. and Huxtable, R. J. (1992) Detection of a reactive pyrrole in the hepatic metabolism of the pyrrolizidine alkaloid, monocrotaline. Toxic. appl. Pharmac. 115, 168-173.
    • (1992) Toxic. Appl. Pharmac. , vol.115 , pp. 168-173
    • Glowaz, S.L.1    Michnika, M.2    Huxtable, R.J.3
  • 5
    • 0028261163 scopus 로고
    • Relationship between in vitro metabolism of pyrrolizidine alkaloids and extrahepatic toxicity in vivo
    • Huxtable, R. J. and Wild, S. L. (1994) Relationship between in vitro metabolism of pyrrolizidine alkaloids and extrahepatic toxicity in vivo. Proc. W. Pharmac. Soc. 37, 109-111.
    • (1994) Proc. W. Pharmac. Soc. , vol.37 , pp. 109-111
    • Huxtable, R.J.1    Wild, S.L.2
  • 7
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    • Toxicity of pyrrolizidine alkaloids
    • Mattocks, A. R. (1968) Toxicity of pyrrolizidine alkaloids. Nature 217, 723-728.
    • (1968) Nature , vol.217 , pp. 723-728
    • Mattocks, A.R.1
  • 8
    • 37049132597 scopus 로고
    • Dihydropyrrolizine derivatives from unsaturated pyrrolizidine alkaloids
    • Mattocks, A. R. (1969) Dihydropyrrolizine derivatives from unsaturated pyrrolizidine alkaloids. J. Chem. Soc. (C), 8, 1155-1162.
    • (1969) J. Chem. Soc. (C) , vol.8 , pp. 1155-1162
    • Mattocks, A.R.1
  • 9
    • 0015402267 scopus 로고
    • Acute hepatotoxicity and pyrrolic metabolites in rats dosed with pyrrolizidine alkaloids
    • Mattocks, A. R. (1972) Acute hepatotoxicity and pyrrolic metabolites in rats dosed with pyrrolizidine alkaloids. Chem.-Biol. Interact. 5, 227-242.
    • (1972) Chem.-biol. Interact. , vol.5 , pp. 227-242
    • Mattocks, A.R.1
  • 11
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    • Trapping and measurement of short-lived alkylating agents in a recirculating flow system
    • Mattocks, A. R. and Jukes, R. (1990) Trapping and measurement of short-lived alkylating agents in a recirculating flow system. Chem.-Biol. Interact. 76, 19-30.
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  • 12
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    • (1989) Toxicon , vol.27 , pp. 561-567
    • Mattocks, A.R.1    Jukes, R.2    Brown, J.3
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    • Yan, C. C., Cooper, R. A. and Huxtable, R. J. (1995) The comparative metabolism of the four pyrrolizidine alkaloids, seneciphylline, retrorsine, monocrotaline and trichodesmine in the isolated perfused rat liver. Toxic. appl. Pharmac. 133, 277-284.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.