The pertussis toxin liberation genes of Bordetella pertussis are transcriptionally linked to the pertussis toxin operon

Infection and Immunity

Volumn 64, Issue 4, 1996, Pages 1458-1460

  Ricci, Stefano ^a   Rappuoli, Rino ^a   Scarlato, Vincenzo ^a  

^a CHIRON VACCINES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; PERTUSSIS TOXIN;

ARTICLE; BORDETELLA PERTUSSIS; DNA SEQUENCE; GENE DELETION; GENE EXPRESSION REGULATION; GENE MAPPING; NONHUMAN; NORTHERN BLOTTING; OPERON; PRIORITY JOURNAL; PROMOTER REGION; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION;

EID: 0030012150     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.4.1458-1460.1996     Document Type: Article

References (19)

1. Aricò, B., J. F. Miller, C. Roy, S. Stibitz, D. M. Monack, S. Falkow, R. Gross, and R. Rappuoli. 1989. Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc. Natl. Acad. Sci. USA 86:6671-6675.
2. Baker, S. M., A. Masi, D.-F. Liu, B. K. Novitsky, and R. A. Deich. 1995. Pertussis toxin export genes are regulated by the ptx promoter and may be required for efficient translation of ptx mRNA in Bordetella pertussis. Infect. Immun. 63:3920-3926.
3. Berk, A. J., and P. A. Sharp. 1977. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell 12:721-723.
4. Coote, J. G. 1991. Antigenic switching and pathogenicity environmental effects on virulence gene expression in Bordetella pertussis. J. Gen. Microbiol. 137:2493-2503.
5. Covacci, A., and R. Rappuoli. 1993. Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon. Mol. Microbiol. 8:429-434.
6. Johnson, F. D., and D. L. Burns. 1994. Detection and subcellular localization of three Ptl proteins involved in the secretion of pertussis toxin from Bordetella pertussis. J. Bacteriol. 176:5350-5356.
7. Kotob, S. I., S. Z. Hausman, and D. L. Burns. 1995. Localization of the promoter of the ptl genes of Bordetella pertussis, which encode proteins essential for secretion of pertussis toxin. Infect. Immun. 63:3227-3230.
8. Kuldau, G. A., G. de Vos, J. Owen, G. McCaffrey, and P. Zambryski. 1990 The virB operon of Agrobacterium tumefaciens pTiC58 encodes 11 open reading frames. Mol. Gen. Genet. 221:256-266.
9. Miller, J. F., J. J. Mekalanos, and S. Falkow. 1989. Coordinate regulation and sensory transduction in the control of bacterial virulence. Science 243: 916-922.
10. Nicosia, A., M. Perugini, C. Franzini, M. C. Casagli, M. G. Borri, G. Antoni. M. Almoni, P. Neri, G. Ratti, and R. Rappuoli. 1986 Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. Proc Natl. Acad. Sci. USA 83:4631-4635.
11. AL, p. 388-393 In N R. Krieg and J. G. Holt (ed.), Bergey's manual of systematic bacteriology, vol. 1. Williams & Wilkins, Baltimore
12. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
13. Scarlato, V., B. Aricò, S. Goyard, S. Ricci, R. Manetti, A. Prugnola, R. Manetti, P. Polverino De Laureto, A. Ullmann, and R. Rappuoli. 1995. A novel chromatin-forming histone H1 homologue is encoded by a dispensable and growth-regulated gene in Bordetella pertussis. Mol Microbiol. 15:871-881.
14. Scarlato, V., B. Aricò, A. Prugnola, and R. Rappuoli. 1991. Sequential activation and environmental regulation of virulence genes in Bordetella pertussis. EMBO J. 10:3971-3975.
15. Scarlato, V., A. Prugnola, B. Aricò, and R. Rappuoli. 1990 Positive transcriptional feedback at the byg locus controls expression of virulence factors in Bordetella pertussis. Proc. Natl. Acad. Sci. USA 87:6753-6757.
16. Simon, R., V. Priefer, and A. Puhler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria Bio/Technology 1:784-789.
17. Stainer, D. W., and M. J. Scholte. 1970. A simple chemically defined medium for the production of phase I Bordetella pertussis. J. Gen. Microbiol. 63:211-220.
18. Stibitz, S., and M.-S. Yang. 1991. Subcellular localization and immunological detection of proteins encoded by the vir locus of Bordetella pertussis. J. Bacteriol. 173:4288-4296.
19. Weiss, A. A., F. D. Johnson, and D. L. Burns. 1993. Molecular characterization of an operon required for pertussis toxin secretion Proc. Natl. Acad Sci. USA 90:2970-2974.