Regional localisation of two non-specific X-linked mental retardation genes (MRX30 and MRX31)

American Journal of Medical Genetics

Volumn 64, Issue 1, 1996, Pages 113-120

  Donnelly, Andrew J ^a,b   Partington, Michael W ^c   Ryan, Anna K ^c   Mulley, John C ^a,b  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

linkage; MRX30; MRX31; X linked mental retardation

Indexed keywords

ADULT; ARTICLE; CENTROMERE; CHROMOSOME XQ; FEMALE; GENE LOCATION; GENE LOCUS; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DEFICIENCY; PEDIGREE ANALYSIS; PRIORITY JOURNAL; X CHROMOSOME LINKED DISORDER;

CHROMOSOME MAPPING; DEVELOPMENTAL DISABILITIES; FEMALE; HETEROZYGOTE DETECTION; HUMANS; INFANT; LINKAGE (GENETICS); MALE; MENTAL RETARDATION; PEDIGREE; X CHROMOSOME;

EID: 0030011779     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19960712)64:1<113::AID-AJMG19>3.0.CO;2-Q     Document Type: Article

References (32)

1. Adams MD, Kerlavage AR, Fields C, Ventor JC (1993): 3,400 new expressed sequence tags identify diversity of transcripts in human brain. Nature Genet 4:256-267.
2. Ballabio A, Bardoni B, Carrozzo R, Andria G, Bick D, Campbell L, Hamel B, Ferguson-Smith MA, Gimelli G, Fraccaro M, Marashio P, Zuffardi O, Guioli S, Camerino G (1989): Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome. Proc Natl Acad Sci USA 86:10001-10005.
3. Black GCM, Chen Z-Y, Craig IW, Powell JF (1991): Dinucleotide repeat polymorphism at MAOA locus. Nuc Acids Res 19:689.
4. Browne D, Barker D, Litt M (1992a): Dinucleotide repeat polymorphisms at the DXS365, DXS443 and DXS451 loci. Hum Mol Genet 1:213.
5. Browne DL, Zoanna J, Litt M (1992b): Dinucleotide repeat polymorphism at the PGK1P1 locus. Nuc Acids Res 20:1169.
6. Chang Y-PC, Smith KD, Dover GJ (1994): Dinucleotide repeat polymorphisms at the DXS85, DXS16 and DXS43 loci. Hum Mol Genet 3:1029.
7. Coleman MP, Murray JC, Willard HF, Nolan KF, Reid KBM, Blake DJ, Lindsay S, Bhattacharya SS, Wright A, Davies KE (1991): Genetic and physical mapping around the properdin P gene. Genomics 11:991-996.
8. Cox TC, Kozman HM, Raskind WH, May BA, Mulley JC (1992): Identification of a highly polymorphic marker within intron 7 of the ALAS2 gene and suggestion of at least two loci for X-linked sideroblastic anemia. Hum Mol Genet 1:639-641.
9. Donnelly AJ, Choo KHA, Kozman HM, Gedeon AK, Danks DM, Mulley JC (1994a): Regional localisation of a non-specific X-linked mental retardation gene (MRX19) to Xp22. Am J Med Genet 51: 581-585.
10. Donnelly A, Kozman H, Gedeon AK, Webb S, Lynch M, Sutherland GR, Richards RI, Mulley JC (1994b): A linkage map of microsatellite markers on the human X chromosome. Genomics 20:363-370.
11. Edwards A, Civitello A, Hammond HA, Caskey CT (1991): DNA typing and genetic mapping with trimeric and tetrameric repeats. Am J Hum Genet 49:746-756.
12. Feener CA, Boyce FM, Kunkel LM (1991): Rapid detection of CA polymorphisms in cloned DNA: Application to the 5′ region of the dystrophin gene. Am J Hum Genet 48:621-627.
13. Freije D, Helms C, Watson MS, Donis-Keller H (1992): Identification of a second pseudoautosomal region near the Xq and Yq telomeres. Science 258:1784-1787.
14. Gedeon AK, Donnelly AJ, Kerr B, Turner G, Mulley JC (1996): Letter to the editor: How many X-linked genes for non-specific mental retardation (MRX) are there? Am J Med Genet 64:158-162.
15. Gedeon AK, Holman K, Richards RI, Mulley J (1992): Characterisation of new PCR based markers for mapping and diagnosis: AC dinucleotide repeat markers at the DXS237 (GMGX9) and DXS102 (cX38.1) loci. Am J Med Genet 43:255-260.
16. Herbst DS, Miller JR (1980): Non-specific X-linked mental retardation. II: The frequency in British Columbia. Am J Med Genet 7:461-469.
17. Knight SJL, Flannery AV, Hirst MC, Campbell L, Christodoulou Z, Phelps SR, Pointon J, Middleton-Price HR, Barnicoat A, Pembrey ME, Holland J, Oostra BA, Bobrow M, Davies KE (1993): Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation. Cell 74:127-134.
18. Lathrop GM and Lalouel JM (1984): Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet 36:460-465.
19. Lathrop GM, Lalouel J-M, Julier C, Ott J (1984): Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci USA 81: 3443-3446.
20. Luty JA, Guo Z, Willard HF, Ledbetter DH, Ledbetter S, Litt M (1990): Five polymorphic microsatellite VNTRs on the human X chromosome. Am J Hum Genet 46:776-783.
21. Mandel J-L (1994): Towards identification of X-linked mental retardation genes: A proposal. Am J Med Genet 51:550-552.
22. May M, Colleaux L, Murgia A, Aylsworth A, Nussbaum R, Fontes M, Schwartz C (1995): Molecular analysis of four males with mental retardation and deletions of Xq21 places the putative MR region in Xq21.1 between DXS233 and CHM. Hum Molec Genet 4:1465-1466.
23. Mulley JC, Kerr B, Stevenson R, Lubs H (1992): Nomenclature guidelines for X-linked mental retardation. Am J Med Genet 43:383-391.
24. Neri G, Chiurazzi P, Arena JF, Lubs H (1994): XLMR genes: Update 1994. Am J Med Genet 51:542-549.
25. Oberlé I, Rousseau F, Heitz D, Kretz C, Devys D, Hanauer A, Bové J, Bettheas MF, Mandel JL (1991): Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252:1097-1102.
26. Ott J (1991): "Analysis of Human Genetic Linkage." Revised ed. Baltimore, MD: Johns Hopkins University Press.
27. Richards RI, Shen Y, Holman K, Kozman H, Hyland VJ, Mulley JC, Sutherland GR (1991): Fragile X syndrome: Diagnosis using highly polymorphic microsatellite markers. Am J Hum Genet 48: 1051-1057.
28. Sutherland GR, Hecht F (1985): "Fragile sites on human chromosomes." New York: Oxford University Press.
29. Van der Maarel SM, Rohme D, Bach I, Gilgenkranz S, Olde Weghuis D, Kere J, Cremers FPM, Ropers H-H (1994): Cloning of a candidate gene for X-linked mental retardation in Xq13.1. Cytogenet Cell Genet 67:349.
30. Weber JL, Kwitek AE, May PE, Polymeroupoulos MH, Ledbetter S (1990): Dinucleotide repeat polymorphisms at the DXS453, DXS454, DXS458 loci. Nuc Acids Res 18:4037.
31. Weissenbach J, Gyapay G, Dib C, Vignal A, Morissette J, Millasseau P, Vaysseix G, Lathrop M (1992): A second generation linkage map of the human genome. Nature 359:794-601.
32. Yu S, Pritchard M, Kremer E, Lynch M, Nancarrow J, Baker E, Holman K, Mulley JC, Warren ST, Schlessinger D, Sutherland GR, Richards RI (1991): Fragile X genotype characterized by an unstable region of DNA. Science 252:1179-61.