Antioxidants in peripheral nerve

Free Radical Biology and Medicine

Volumn 20, Issue 7, 1996, Pages 925-932

  Romero, Francisco J ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

4 Hydroxynonenal; Antioxidants; Free radicals; Glutathione; Neuropathies; Protein kinase C; Sciatic nerve

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIOXIDANT; GLUTATHIONE; PHENYTOIN; PROTEIN KINASE C;

CENTRAL NERVOUS SYSTEM DISEASE; DIABETIC NEUROPATHY; ELECTROPHYSIOLOGY; LIPID PEROXIDATION; MYELIN SHEATH; NERVE FUNCTION; NERVOUS TISSUE; NEUROPATHY; OXIDATIVE STRESS; PERIPHERAL NERVE; PRIORITY JOURNAL; REVIEW; SCIATIC NERVE;

EID: 0030011675     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(95)02183-3     Document Type: Review

References (112)

1. Cadenas, E. Biochemistry of oxygen toxicity. Annu. Rev. Biochem. 58:79-110; 1989.
2. Sies, H., ed. Oxidative stress: Oxidants and antioxidants. London: Academic Press; 1991.
3. Ursini, F.; Cadenas, E., eds. Biological free radical oxidations and antioxidants. Padova: CLEUP University Publisher; 1992.
4. Sies, H. Oxidative stress: Introductory remarks. In: Sies, H., ed. Oxidative stress. London: Academic Press; 1985:1-8.
5. Cadet, J. L. The potential use of vitamin E and selenium in parkinsonism. Med. Hypothesis 20:87-94; 1986.
6. Gotz, M. E.; Freyberger, A.; Riedere, R. P. Oxidative stress: A role in the pathogenesis of Parkinson's disease. J. Neural Transm. Suppl. 29:241-249; 1990.
7. Adams, J. D.; Odunze, I. N. Oxygen free radicals and Parkinson's disease. Free Radic. Biol. Med. 10:161-169; 1991.
8. Adams, J. D.; Klaidman, L. K.; Odunze, I. N.; Shen, H. C.; Miller, C. A. Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide and vitamin E. Mol. Chem. Neuropathol. 14:213-226; 1991.
9. Rosen, D. R.; Siddique, T.; Patterson, D.; Figlewicz, D. A.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J. P.; Deng, H. X. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362:59-62; 1993.
10. Ceballos, I.; Javoy-Agid, F.; Delacourte, A.; Defossez, A.; Nicole, A.; Sinet, P. M. Parkinson's disease and Alzheimer's disease: Neurodegenerative disorders due to brain antioxidant system deficiency? Adv. Exp. Med. Biol. 264:493-498; 1990.
11. Vanlente, F. Free radicals. Anal. Chem. 63:R199-R202; 1991.
12. Braughler, J. M.; Hall, E. D. Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic. Biol. Med. 6:289-301; 1989.
13. Hall, E. D.; Braughler, J. M. Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic. Biol. Med. 6:303-313; 1989.
14. Aleksandrovskii, I.; Poiurovskii, M. V.; Neznamov, G. G.; Seredeniia, S. B.; Krasova, E. A. Lipid peroxidation in emotional stress and neurotic disorders. Zh. Nevropatol. Psikhiatr. 88:95-101: 1988.
15. Mori, A.; Hiramatsu, M.; Yokoi, I.; Edamatsu, R. Biochemical pathogenesis of posttraumatic epilepsy. Pavlov J. Biol. Sci. 25:54-62; 1990.
16. Low, P. A.; Nickander, K. A. Oxygen free radical effects in sciatic nerve in experimental diabetes. Diabetes 40:873-877; 1991.
17. Tsushima, R. G.; Moffat, M. P. Differential effects of purine/xanthine oxidase on the electrophysiologic characteristics of ventricular tissues. J. Cardiovasc. Pharmacol. 16:50-58; 1990.
18. Hall, E. D.; Braughler, J. M.; McCall, J. M. New pharmacological treatments of acute spinal cord trauma. J. Neurotrauma 5:81-89; 1988.
19. Monyer, H.; Hartley, D. M.; Choi, D. W. 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron 5:121-126; 1990.
20. Hall, E. D.; Yonkers, P. A. Preservation of motor nerve function during early degeneration by the 21-aminosteroid antioxidant U74006F. Brain Res. 513:244-247; 1990.
21. Beck, T.; Bielenberg, G. W. The effects of two 21-aminosteroids on overt infarct size 48 hours after middle cerebral artery occlusion in the rat. Brain Res. 560:159-162; 1991.
22. Sutherland, G.; Haas, N.; Peeling, J. Ischemic neocortical protection with U74006F - A dose-response curve. Neurosci. Lett. 149:123-125; 1993.
23. Hall, E. D.; Mccall, J. M.; Means, E. D. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv. Pharmacol. 28:221-268; 1994.
24. Andrus, P. K.; Taylor, B. M.; Sun, F. F.; Hall, E. D. Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion. Brain Res. 659:126-132; 1994.
25. Lebel, C. P.; Bondy, S. C. Oxygen radicals. Common mediators of neurotoxicity. Neurotoxicol. Teratol. 13:341-346; 1991.
26. Kosower, N. S.; Kosower, E. M. The glutathione status of cells. Int. Rev. Cytol. 54:109-160; 1978.
27. Smith, H. M. Effects of sulfhydryl blockade on axonal function. J. Cell Comp. Physiol. 51:161-171; 1958.
28. Huneeus-Cox, F.; Fernandez, H. L.; Smith, B. H. Effects of redox and sulfhydryl reagents on the bioelectric properties of the giant axon of the squid. Biophys. J. 6:675-689; 1966.
29. Marquis, J. K.; Mautner, H. G. The effect of electrical stimulation on the action of sulfhydryl reagents in the giant axon of squid: Suggested mechanisms for the role of thiol and disulfide groups in electrically induced conformational changes. J. Membr. Biol. 15:249-260; 1974.
30. Shrager, P. Specific chemical groups involved in the control of ionic conductance in nerve. Ann. NY Acad. Sci. 264:293-303; 1975.
31. Shrager, P. Slow sodium inactivation in nerve after exposure to sulfhydryl blocking reagents. J. Gen. Physiol. 69:183-202; 1977.
32. Philbert, M. A.; Beiswanger, C. M.; Waters, D. K.; Reuhl, K. R.; Lowndes, H. E. Cellular and regional distribution of reduced glutathione in the nervous system of the rat: Histochemical localization by mercury orange and o-pbthaldialdehyde-induced histofluorescence. Toxicol. Appl. Pharmacol. 107:215-227; 1991.
33. Romero, F. J.; Romá, J. Glutathione and protein kinase C in peripheral nervous tissue. Methods Enzymol. 252:146-153; 1995.
34. Romero, F. J.; Segura-Aguitar, J.; Monsalve, E.; Hermenegildo, C.; Nies, E.; Puertas, F. J.; Romá, J. Antioxidant and glutathione-related enzymatic activities in rat sciatic nerve. Neurotoxicol. Teratol. 12:603-605; 1990.
35. Romero, F. J.; Monsalve, E.; Hermenegildo, C.; Puertas, F. J.; Higueras, V.; Nies, E.; Segura-Aguilar, J.; Romá, J. Oxygen toxicity in the nervous tissue: Comparison of the antioxidant defense of rat brain and sciatic nerve. Neurochem. Res. 16:157-161; 1991.
36. Yaari, Y.; Selzer, M. E.; Pincus, J. H. Phenytoin: Mechanisms of its anticonvulsant action. Ann. Neurol. 20:171 -184; 1986.
37. So, E. L.; Penry, J. K. Adverse effects of phenytoin on peripheral nerves and neuromuscular junction: A review. Epilepsia 22:467-473; 1981.
38. Swift, T. R.; Gross, J. A.; Ward, L. C.; Crout, B. O. Peripheral neuropathy in epileptic patients. Neurology 31:826-831; 1981.
39. Danner, R. Electrophysiological effects of diphenylhydantoin and carbamazepine on the peripheral and central nervous tissue. Acta Neurol. Scand. 65:668-680; 1982.
40. LeQuesne, P. M.; Goldberg, V.; Vajda, F. Acute conduction velocity changes in guinea pigs after administration of diphenylhydantoin. J. Neurol. Neurosurg. Psychiatry 39:995-1000: 1976.
41. Marcus, D. J.; Swift, T. R.; McDonald, T. F. Acute effects of phenytoin on peripheral nerve function in the rat. Muscle Nerve 4:48-50; 1981.
42. Romá, J.; Cuervo, A. M.; Macián, F.; Raya, A.; Gallego, J.; Llopis, J. E.; Romero, F. J. Temperature dependence of the toxic effects of phenytoin on peripheral neuromuscular function of the rat tail, Neurotoxicol, Teratol. 12:627-631; 1990.
43. Quandt, F. N. Modification of slow inactivation of single sodium channels by phenytoin in neuroblastoma cells. Mol. Pharmacol. 34:557-565; 1988.
44. Schwarz, J. R.; Grigat, G. Phenytoin and carbamazepine: potential- and frequency-dependent block of Na currents in mammalian myelinated nerve fibers. Epilepsia 30:286-294: 1989.
45. Pincus, J. H.; Lee, S. Diphenylhydantoin and calcium. Arch. Neurol. 26:239-244; 1973.
46. Pincus, J. H.; Weinfeld, H. M. Acetylcholine release from synaptosomes and phenytoin action. Brain Res. 296:313-317; 1984.
47. Messing, R. O.: Carpenter, C. L.; Greenberg, D. A. Mechanism of calcium channel inhibition by phenytoin: Comparison with classical calcium channel antagonists. J. Pharmacol. Exp. Ther. 235:407-411; 1985.
48. Pincus, J. H.; Kiss, A. Phenytoin, tetrodoxin, and acetylcholine release. Exp. Neurol. 94:777-781; 1986.
49. Woodbury, D. M. Effect of diphenylhydantoin on electrolytes and radiosodium turnover in brain and other tissues of normal, hyponatremic and postictal rats. J. Pharmacol. Exp. Ther. 115:74-95; 1955.
50. Rawson, M. D.; Pincus, J. H. The effect of diphenylhydantoin on Na, K, Mg activated adenosine triphosphatase in microsomal fractions of rat and guinea pig brain and on whole homogenates of human brain. Biochem. Pharmacol. 17:573-579; 1968.
51. +)-ATPase in C57/BL mice. J. Neurochem. 47:904-911; 1986.
52. Shearman, M. S.; Sekiguchi, K.; Nishizuka, Y. Modulation of ion channel activity: A key function of the protein kinase C enzyme family. Pharmacol. Rev. 41:211-237; 1989.
53. +-ATPase by protein kinase C. Biochim. Biophys. Acta 1052:143-151; 1990.
54. +-ATPase is an effector protein for protein kinase C in renal proximal tubule cells. Am. J. Physiol 256:F370-F373; 1989.
55. +-ATPase in oocytes of Xenopus laevis. J. Membrane Biol. 118:131-142; 1990.
56. +-pump. J. Biol. Chem. 261:14551-14556; 1986.
57. Yeh, L. A.; Ling, L.; English, L.; Cantley, L. Phosphorylation of the (Na,K)-ATPase by a plasma membrane-bound protein kinase in friend erythroteukemia cells. J. Biol. Chem. 258:6567-6574; 1983.
58. +)-ATPase of friend erythroleukemia cells is phosphorylated near the ATP hydrolysis by an endogenous membrane-bound kinase. J. Biol. Chem. 259:4089-4095; 1984.
59. +-ATPase and sodium pump by protein kinase C regulated sphingosine, lysophosphatidylcholine, and oleic acid. J. Biol. Chem. 265:70-75; 1990.
60. +-ATPase inhibits the activity of the enzyme. Proc. Natl. Acad. Sci. USA 88:11359-11362; 1991.
61. + transport across frog skin. J. Membr. Biol. 121:37-50; 1991.
62. Raya, A.; Gallego, J.; Hermenegildo, C.; Puertas, F. J.; Romero, F. J.; Felipo, V.; Miñana, M.-D.; Grisolía, S.; Romá, J. Prevention of the acute neurotoxic effects of phenytoin on rat peripheral nerve by H7, an inhibitor of protein kinase C. Toxicology 75:249-256; 1992.
63. Raya, A.; Gallego, J.; Bosch-Morell, F.; Roma, J.; Romero, F. J. Phenytoin-induced glutathione depletion in rat peripheral nerve. Free Radic. Biol. Med. 19:665-667; 1995.
64. Perchellet, J.-P.; Perchellet, E. M. Antioxidants and multistage carcinogenesis in mouse skin. Free Radic. Biol. Med. 7:377-408; 1989.
65. Schäfer, A.; Wieser, R. J.; Romero, F. J.; Oesch, F. Reduction of glutathione content by 12-O-tetradecanoylphorbol-13-acctate in confluent but not in sparse cultures of human diploid fibroblasts. Carcinogenesis 11:697-699; 1990.
66. Johansson, B.; Magnusson, K. E. Oxygen metabolites induced by phorbol myristate acetate increase lateral diffusion of wheat germ agglutinin-labeled glycoconjugates in human polymorphonuclear leukocytes. Inflammation 14:631-644; 1990.
67. Miñana, M-D.; Felipo, V.; Grisolía, S. Inhibition of protein kinase C induces differentiation of neuroblastoma cells. FEBS Lett. 255:184-186; 1989.
68. Keyser, D. O.; Alger, B, E. Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals. Neuron 5:545-553; 1990.
69. Felipo, V.; Miñana, M.-D.; Grisolía, S. A specific inhibitor of protein kinase C induces differentiation of neuroblastoma cells. J. Biol. Chem. 265:9599-9601; 1990.
70. Miñana, M.-D.; Felipo, V.; Grisolía, S. Inhibition of protein kinase C induces differentiation in neuro-2a cells. Proc. Natl. Acad. Sci. USA 87:4335-4339; 1990.
71. +-ATPase activity in sciatic nerve of diabetic mice. J. Neurochem. 58:1246-1249; 1992.
72. Romero, F. J.; Llopis, J.; Felipo, V.; Miñana, M.-D.; Romá, J.; Grisolía, S, H7, a protein kinase C inhibitor, increases the glutathione content of neuroblastoma cells. FEBS Lett. 303:19-21; 1992.
73. Ziegler, D.; Gries, F. A.; Spuler, M.; Lessmann, F. The epidemiology of diabetic neuropathy. DiaCAN Multicenter Study Group. Diabetes Med. 10:82S-86S; 1993.
74. Dyck, P. J.; Kratz, K. M.; Karnes, J. L.; Litchy, W. J.; Klein, R.; Pach, J. M.; Wilson, D. M.; O'Brien, P. C.; Melton, L. J.; Service, F. J. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: The Rochester Diabetic Neuropathy Study. Neurology 43:817-824; 1993.
75. O'Hara, J. A.; Abuaisha, F.; Geoghegan, M. Prevalence and forms of neuropathic morbidity in 800 diabetics, Ir. J. Med. Sci. 163:132-135; 1994.
76. Low, P. A.; Ward, K.; Schmelzer, J. D.; Brimijoin, S. Ischemic conduction failure and energy metabolism in experimental diabetic neuropathy. Am. J. Physiol. 248:E457-E462; 1985.
77. Low, P. A.; Logerlund, T. D.; McManis, P. G. Nerve blood flow and oxygen delivery in normal, diabetic, and ischemic neuropathy. Int. Rev. Neurobiol. 31:355-438; 1989.
78. Cameron, N. E.; Cotter, M. A.; Low, P. A. Nerve blood flow in early experimental diabetes in rats: Relation to conduction deficits. Am. J. Physiol. 261:E1-E8; 1991.
79. Low, P. A.; Tuck, R. R.; Takeuchi, M. Nerve microenvironment in diabetic neuropathy. In: Dyck, P. J.; Thomas, P. K.; Asbury, A. K.; Winegrad, A. I., eds. Diabetic neuropathy. Philadelphia, PA: Saunders; 1987:266-278.
80. Baynes, J. W. Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412; 1991.
81. Kihara, M.; Schmelzer, J. D.; Poduslo, J. F.; Curran, G. L.; Nickander, K. K.; Low, P. A. Aminoguanidine effects on nerve blood flow, vascular permeability, electrophysiology, and oxygen free radicals. Proc. Natl. Acad. Sci. USA 88:6107-6111; 1991.
82. Williamson, J. R.; Chang, K.; Frangos, M.; Hasan, K. S.; Ido, Y.; Kawamura, T.; Nyengaard, J. R.; Enden, M. v. d.; Kilo, C.; Tilton, R. G. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 42:801-813; 1993.
83. Greene, D. A.; Sima, A. A. F.; Pfeifer, M. A.; Albers, J. W. Diabetic neuropathy. Annu. Rev. Med. 41:303-317; 1990.
84. Hermenegildo, C.; Raya, A.; Romá, J.; Romero, F. J. Decreased glutathione peroxidase activity in sciatic nerve of alloxan-induced diabetic mice and its correlation with blood glucose levels. Neurochem. Res. 18:893-896; 1993.
85. +-ATPase defect in experimental diabetic neuropathy. Diabetes 35:1282-1285; 1986.
86. Nagamatsu, M.; Nickander, K.; Schmelzer, J. D.; Raya, A.; Wittrock, D. A.; Tritschler, H.; Low, P. A. Lipoic acid improves nerve blood flow, reduces oxidative stress and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 18:1160-1167; 1995.
87. Hunt, J. V.; Dean, R. T.; Wolff, S. P. Hydroxyl radical production and autoxidative glycosylation. Biochem. J. 256:205-212; 1988.
88. Pigeolet, E.; Corbisier, P.; Houbion, A.; Lambert, D.; Michiels, C.; Raes, M.; Zachary, M.-D.; Remacle, J. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals. Mech. Age. Dev. 51:283-297; 1990.
89. Cameron, N. E.; Cotter, M. A. The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications. Diabetes Metab. Rev. 10:189-224; 1994.
90. +-ATPase activity in sciatic nerve of diabetic mice by administration of H7 or calphostin C, inhibitors of protein kinase C. Diabetes 42:257-262; 1993.
91. Raya, A.; Hermenegildo, C.; Romero, F. J.; Romá, J. Acute ethanol administration in the rat peripheral nervous system: Electrophysiological alterations appear associated with glutathione depletion. Eur. J. Neurosci. Suppl. 5:299; 1992.
92. Raya, A. Ph.D. Thesis. University of Valencia; 1995.
93. Rouach, H.; Ribière, C.; Park, M. K.; Saffar, C.; Nordmann, R. Lipid peroxidation and brain mitochondrial damage induced by ethanol. Bioelectrochem. Bioenerget. 18:211-217; 1987.
94. Uysal, M.; Kutalp, G.; Ozdemirler, G.; Aykaçc, G. Ethanol-induced changes in lipid peroxidation and glutamione content in rat brain. Drug Alcohol Depend. 23:227-230; 1989.
95. Rouach, H.; Park, M. K.; Orfanelli, M. T.; Janvier, B.; Nordmann, R. Ethanol-induced oxidative stress in the rat cerebellum. Alcohol Alcohol. Suppl. 1:207-211; 1987.
96. +) ATPase of rats. Eur. J. Biochem. 86:581-587; 1978.
97. Windebank, A. J. Specific inhibition of myelination by lead in vitro; Comparison with arsenic, thallium, and mercury. Exp. Neurol. 94:203-212; 1986.
98. Arvidson, B. Inorganic mercury is transported from muscular nerve terminals to spinal and brainstem motoneurons. Muscle Nerve 15:1089-1094; 1992.
99. Arvidson, B. A review of axonal transport of metals. Toxicology 88:1994.
100. Sarafian, T.; Verity, M. A. Oxidative mechanisms underlying methyl mercury neurotoxicity. Int. J. Dev. Neurosci. 9:147-153; 1991.
101. Sarafian, T. A.; Vartavarian, L.; Kane, D. J.; Bredesen, D. E.; Verity, M. A. bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line. Toxicol. Lett. 74:149-155; 1994.
102. Williams, D. B.; Windebank, A. J. Motor neuron disease (amyotrophic lateral sclerosis). Mayo Clin. Proc. 66:54-82; 1991.
103. Goonetilleke, A.; deBelleroche, J.; Guiloff, R. J. Motor neurone disease. Essays Biochem. 28:27-45; 1994.
104. Pramatarova, A.; Figlewicz, D. A.; Krizus, A.; Han, F. Y.; Ceballos-Picot, I.; Nicole, A.; Dib, M.; Meininger, V.; Brown, R. H.; Rouleau, G. A. Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis. Am. J. Hum. Genet. 56:592-596; 1995.
105. Bowling, A. C.; Schulz, J. B.; Brown, R. H.; Beal, M. F. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61:2322-2325; 1993.
106. Bergeron, C.; Muntasser, S.; Somerville, M. J.; Weyer, L.; Percy, M. E. Copper/zinc superoxide dismutase mRNA levels are increased in sporadic amyotrophic lateral sclerosis motorneurons. Brain Res. 659:272-276; 1994.
107. Verity, M. A. Oxidative damage and repair in the developing nervous tissue. Neurotoxicology 15:81-91; 1994.
108. Ratan, R. R.; Murphy, T. H.; Baraban, J. M. Oxidative stress induces apoptosis in embryonic cortical neurons. J. Neurochem. 62:376-379; 1994.
109. Cotman, C. W.; Anderson, A. J. A potential role for apoptosis in neurodegeneration and Alzheimer' s disease. Mol. Neurobiol. 10:19-45; 1995.
110. Chvapil, M.; Kern, J. M.; Misiorowski, R.; Weinstein, P. R. Endogenous antioxidants and rate of malondialdehyde formation in central and peripheral nervous systems. Exp. Neurol. 78:765-774; 1982.
111. Cloëz, I.; Tayarani, I.; Morel, F.; Bourre, J.-M. Alterations in protective enzymes against peroxidation in the central and peripheral nervous system of control and dysmyelinatig mutant mice. J. Neurochem. 52:1353-1358; 1989.
112. Baars, A. J.; Mukhtar, H.; Zoetemelk, C. E. M.; Jansen, M.; Breimer, D. D. Glutathione S-transferase activity in rat and human tissues and organs. Comp. Biochem. Physiol. 70C:285-288; 1981.