Phospholipid signaling in leukocytes

Current Opinion in Hematology

Volumn 3, Issue 1, 1996, Pages 48-54

  Cockcroft, Shamshad ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHOLIPASE; PHOSPHOLIPID; RHO FACTOR;

CELL TRANSPORT; CYTOSKELETON; ENZYME ASSAY; HUMAN; LEUKOCYTE; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030011648     PISSN: 10656251     EISSN: None     Source Type: Journal    
DOI: 10.1097/00062752-199603010-00008     Document Type: Review

References (60)

1. Berridge MJ: Inositol trisphosphate and calcium signalling. Nature 1993, 361:315-325.
2. 3 levels could produce the assembly and disassembly of the actin network.
3. Terui T, Kahn RA, Randazzo PA: Effects of acid phospholipids on nucleotide exchange properties of ADP-ribosylation factor 1. J Biol Chem 1994, 269:28130-28135.
4. 2 but not PI.
5. βγ-subunits and lipid. J Biol Chem 1995, 270:11707-11710.
6. 2 was found to be independently controlled by GTPγS, and PITP was found to be essential. It was therefore suggested that PITP is in fact a cofactor in inositol lipid signaling and acts by interacting with the inositol lipid kinases.
7. 2 synthesis could mediate the effects of Rho on the actin cytoskeleton.
8. Jenkins GH, Fisette PL, Anderson RA: Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J Biol Chem 1994, 269:11547-11554.
9. Kauffmann-Zeh A, Thomas GMH, Ball A, Prosser S, Cunningham E, Cockcroft S, Hsuan JJ: Requirement for phosphatidylinositol transfer protein in epidermal growth factor signalling. Science 1995, 268:1188-1190.
10. 2+-activated secretion. Nature 1995, 374:173-177.
11. Thomas GMH, Cunningham E, Fensome A, Ball A, Totty NF, Troung O, Hsuan JJ, Cockcroft S: An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signalling. Cell 1993, 74:919-928.
12. 2+] homeostasis and tyrosine phosphorylation of phospholipase Cγ2. in HL60 granulocytes. J Biol Chem 1993, 268:3357-3363.
13. Dusi S, Donini M, della Bianca V, Rossi F: Tyrosine phosphorylation of phospholipase C-γ2 is involved in the activation of phosphoinositide hydrolysis by Fc receptors in human neutrophils. Biochem Biophys Res Commun 1994, 201:1100-1108.
14. Wirtz KWA: Phospholipid transfer proteins. Annu Rev Biochem 1991, 60:73-99.
15. Tanaka S, Hosaka K: Cloning of a cDNA encoding a second phosphatidylinositol transfer protein of rat brain by complementation of the yeast sec14 mutation. J Biochem (Tokyo) 1994, 115:981-984.
16. De Vries KJ, Heinrichs AAJ, Cunningham E, Brunink F, Westerman J, Somerharju PJ, Cockcroft S, Wirtz KWA, Snoek GT: An isoform of the phosphatidylinositol transfer protein transfers sphingomyelin and is associated with the golgi system. Biochem J 1995, 310:643-649.
17. Snoek GT, de Wit ISC, van Mourik JHG, Wirtz KWA: The phosphatidylinositol transfer protein in 3T3 mouse fibroblast cells is associated with the golgi system. J Cell Biochem 1992, 49:339-348.
18. Snoek GT, Westerman J, Wouters FS, Wirtz KWA: Phosphorylation and distribution of the phosphatidylinositol-transfer protein in phorbol 12-myristate 13-acetate and bombesin-stimulated Swiss 3T3 fibroblasts. Biochem J 1993, 291:649-656.
19. De Vries KJ, Momchilova-Pankova A, Snoek GT, Wirtz KWA: A novel acidic form of the phosphatidylinositol transfer protein is preferentially retained in permeabilized Swiss mouse 3T3 fibroblasts. Exp Cell Res 1995, 215:109-113.
20. Pike MC, Arndt C: Characterization of phosphatidylinositol and phosphatidylinositol-4-phosphate kinases in human neutrophils. J Immunol 1988, 140:1967-1973.
21. Okada T, Sakuma L, Fukui Y, Hazeki O, Ui M: Blockade of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J Biol Chem 1995, 269:3563-3567.
22. Arcaro A, Wymann P: Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J 1993, 296:297-301.
23. Thelen M, Wymann MP, Langen H: Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Natl Acad Sci U S A 1994, 91:4960-4964.
24. Carpenter CL, Cantley LC: Phosphoinositide kinases. Biochemistry 1990, 29:11147-11156.
25. Wetzker R, Klinger R, Hsuan J, Fry MJ, Kauffmann-Zeh A, Muller E, Frunder H, Waterfield M: Purification and characterization of phosphatidylinositol 4-kinase from human erythrocyte membranes. Eur J Biochem 1991, 200:179-185.
26. Massenburg D, Han J, Liyanage M, Patton WA, Rhee SG, Moss J, Vaughan M: Activation of rat brain phospholipase D by ADP-ribosylation factors 1,5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes. Proc Natl Acad Sci U S A 1994, 91:11718-11722.
27. Endemann GC, Graziani A, Cantley LC: A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase. Biochem J 1991, 273:63-66.
28. Garcia-Bustos JF, Marini F, Stevenson I, Frei C, Hall MN: PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. EMBO J 1994, 13:2352-2361.
29. Prasad KV, Kapeller R, Janssen O, Repke H, Duke-Dohan JS, Cantley LC, Rudd CE: Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase. J Immunol 1994, 152:42-50.
30. Del Vecchio RL, Pilch PF: Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles. J Biol Chem 1991, 266:13278-13283.
31. Moritz A, de Graan PNE, Gispen WH, Wirtz KWA: Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. J Biol Chem 1992, 267:7207-7210.
32. Divecha N, Truong O, Hsuan JJ, Hinchcliffe K, Irvine RF: The cloning and sequencing of the C isoform of PtdIns4P 5-kinase. Biochem J 1995, 309:715-719.
33. Boronenkov IV, Anderson RA: The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases. J Biol Chem 1995, 270:2881-2884.
34. Yamamoto A, DeWald DB, Boronenkov IV, Anderson RA, Emr SD, Koshland D: Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell 1995, 6:525-539.
35. Bazenet CE, Ruano AR, Brockman JL, Anderson RA: The human erythrocyte contains two forms of phosphatidylinositol 4-phosphate 5-kinase which are differentially active toward membranes. J Biol Chem 1990, 265:18012-18022.
36. Hawkins PT, Eguinoa A, Qiu R, Stokoe D, Cooke FT, Walers R, Wennstrom S, Claesson-Welsh L, Evans T, Symons M, Stephens L: POGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr Biol 1995, 5:393-403.
37. Stephens L, Eguinoa A, Corey S, Jackson T, Hawkins PT: Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells. EMBO J 1993, 12:2265-2273.
38. Stephens L, Jackson T, Hawkins PT: Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signaling system? Biochim Biophys Acta 1993, 1179:27-75.
39. Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT: A novel phosphoinositide 3 kinase activity in myeloid-deprived cells is activated by G-protein βγ subunits. Cell 1994, 77:83-93.
40. Thomason PA, James SR, Casey PJ, Downes CP: A G-protein βγ-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol. J Biol Chem 1994, 269:16525-16528.
41. i1 were effective in stimulating the activity of p110γ.
42. Brown HA, Gutowski S, Moomaw CR, Slaughter C, Sternweis PC: ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell 1993, 75:1137-1144.
43. Cockcroft S, Thomas GMH, Fensome A, Geny B, Cunningham E, Gout I, Hues I, Totty NF, Troung O, Hsuan JJ: Phospholipase D: a downstream effector of ARF in granulocytes. Science 1994, 263:523-526.
44. Brown HA, Gutowski S, Kahn R., Sternweis PC: Partial purification and characterization of Arf-sensitive phospholipase D from porcine brain. J Biol Chem 1995, 270:14935-14943.
45. Zhang G, Patton WA, Lee FS, Uyange M, Han J, Rhee SG, Moss JE, Vaughan M: Different ARF domains are required for the activation of cholera toxin and phospholipase D. J Biol Chem 1995, 270:21-24.
46. Bowman EP, Uhlinger DJ, Lambeth JD: Neutrophil phospholipase D is activated by a membrane-associated rho family small molecular weight GTP-binding protein. J Biol Chem 1993, 268:21509-21512.
47. Malcolm KC, Ross AH, Qiu R, Symons M, Exton JH: Activation of rat liver phospholipase D by the small GTP-binding protein RhoA. J Biol Chem 1994, 269:25951-25954.
48. Siddiqi AR, Smith JL, Ross AH, Qiu R, Symons M, Exton JH: Regulation of phospholipase D in HL60 cells. J Biol Chem 1995, 270:8466-8473. In this paper, HL60 cytosol is shown to contain PLD activity that was stimulated by ARF but not RhoA and cdc42H. Membranes also contained a GTPγS-stimulated PLD activity that could be inhibited by removal of RhoA by Rho-GDI. In addition, the membrane activity could be partially recovered by readdition of RhoA, cdc42, and Rac1. ARF also stimulated the membrane PLD activity and the combination of RhoA and ARF showed a synergistic effect. The data suggest the existence of at least two different PLD isozymes in HL60 cells.
49. Singer WD, Brown HA, Bokoch GM, Sternweis PC: Resolved phospholipase D activity is modulated by cytosolic factors other than Art. J Biol Chem 1995, 270:14944-14950. This paper describes the ability of RhoA and cdc42 to activate a partially purified PLD activity alone; in the additional presence of ARF, these Rho proteins are synergistic. In addition, a third cytosolic component is described that is not dependent on guanine nucleotides.
50. Lambeth JD, Kwak J, Bowman EP, Perry D, Uhlinger DJ, Lopez I: ADP-ribosylation factor functions synergistically with a 50-kDa cytosolic factor in cell-free activation of human neutrophil phospholipase D. J Biol Chem 1995, 270:2431-2434. Proteins in both membranes and cytosol are needed to observe GTPγS-stimulated PLD activity. One cytosolic protein that has been identified is ARF. This paper reports on the presence of another cofactor, a 50-kD protein in leukocyte cytosol that also supported GTPγS-stimulated PLD activity in leukocyte membranes. The 50-kD factor was found to be synergistic with ARF in its ability to activate PLD. This paper should be read in conjunction with that by Bourgoin et al. (J Biol Chem 1995, 270:3172-3178).
51. Bourgoin S, Harbour D, Desmarais Y, Takai Y, Beaulieu A: Low molecular weight GTP-binding proteins in HL60 granulocytes. J Biol Chem 1995, 270:3172-3178. This paper should be read in conjunction with that by Lambeth et al. (J Biol Chem 1995, 270:2431-2434).
52. Okamura S, Yamashita S: Purification and characterization of phosphatidylcholine phospholipase D from pig lung. J Biol Chem 1994, 269:31207-31213.
53. Whatmore J, Cronin P, Cockcroft S: ARF1-regulated phospholipase D in human neutrophils is enhanced by PMA and MgATP. FEBS Lett 1994, 352:113-117.
54. Conricode KM, Brewer KA, Exton JH: Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism. J Biol Chem 1992, 267:7199-7202.
55. Conricode KM, Smith JL, Burns DJ, Exton JH: Phospholipase D activation In fibroblast membranes by the a and β isoforms of protein kinase C. FEBS Lett 1994, 342:149-153.
56. Kusner DJ, Schomisch SJ, Dubyak GR: ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes. J Biol Chem 1993, 268:19973-19982.
57. Pertile P, Liscovitch M, Chalifa V, Cantley LC: Phosphatidylinositol 4,5-bisphosphate synthesis is required for activation of phospholipase D in U937 cells. J Biol Chem 1995, 270:5130-5135.
58. Buhl AM, Avdi N, Worthen GS, Johnson GL: Mapping of the C5a receptor signal transduction network in human neutrophils. Proc Natl Acad Sci U S A 1994, 91:9190-9194.
59. Biesen van T, Hawes BE, Luttrell DK, Krueger KM, Touhara K, Porfiri, Sakaue M, Lutrell LM, Lefkowitz RJ: Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway. Nature 1995, 376:781-784.
60. 2.