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Volumn 45, Issue 1, 1996, Pages 27-32

Low dose recombinant human growth hormone normalizes bone metabolism and cortical bone density and improves trabecular bone density in growth hormone deficient adults without causing adverse effects

Author keywords

[No Author keywords available]

Indexed keywords

OSTEOCALCIN; PARATHYROID HORMONE; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; VITAMIN D;

EID: 0030011159     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2265.1996.tb02056.x     Document Type: Article
Times cited : (61)

References (61)
  • 2
  • 4
    • 0025736724 scopus 로고
    • Growth hormone (GH) receptors in clonal osteoblastic-like cells mediate a mitogenic response to GH
    • Barnard, R., Ng, K.W., Martin, T.J. & Waters, M.J. (1991) Growth hormone (GH) receptors in clonal osteoblastic-like cells mediate a mitogenic response to GH. Endocrinology, 128, 1459-1464.
    • (1991) Endocrinology , vol.128 , pp. 1459-1464
    • Barnard, R.1    Ng, K.W.2    Martin, T.J.3    Waters, M.J.4
  • 7
    • 0028927751 scopus 로고
    • The effects of prolonged growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults
    • Beshyah, S.A., Kyd, P., Thomas, E., Fairney, A. & Johnston, D.G. (1995b) The effects of prolonged growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults. Clinical Endocrinology, 42, 249-254.
    • (1995) Clinical Endocrinology , vol.42 , pp. 249-254
    • Beshyah, S.A.1    Kyd, P.2    Thomas, E.3    Fairney, A.4    Johnston, D.G.5
  • 8
    • 0028242060 scopus 로고
    • The effect of growth hormone replacement therapy in hypopituitary adults on calcium and bone metabolism
    • Beshyah, S.A., Thomas, E., Kyd, P., Sharp, P., Fairney, A. & Johnston, D.G. (1994) The effect of growth hormone replacement therapy in hypopituitary adults on calcium and bone metabolism. Clinical Endocrinology, 40, 383-391.
    • (1994) Clinical Endocrinology , vol.40 , pp. 383-391
    • Beshyah, S.A.1    Thomas, E.2    Kyd, P.3    Sharp, P.4    Fairney, A.5    Johnston, D.G.6
  • 9
    • 0028298830 scopus 로고
    • Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts
    • Birnbaum, R.S. & Wiren, K.M. (1994) Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts. Endocrinology, 135, 223-230.
    • (1994) Endocrinology , vol.135 , pp. 223-230
    • Birnbaum, R.S.1    Wiren, K.M.2
  • 10
    • 0027308906 scopus 로고
    • Serum levels of insulin-like growth factor I (IGF-I) and IGF binding protein 3 reflect spontaneous growth hormone secretion
    • Blum, W.F., Albertsson-Wikland, K., Rosberg, S. & Ranke, B.R. (1993) Serum levels of insulin-like growth factor I (IGF-I) and IGF binding protein 3 reflect spontaneous growth hormone secretion. Journal of Clinical Endocrinology and Metabolism, 76, 1610-1616.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 1610-1616
    • Blum, W.F.1    Albertsson-Wikland, K.2    Rosberg, S.3    Ranke, B.R.4
  • 12
    • 0026329377 scopus 로고
    • Growth hormone and bone
    • Bouillon, R. (1991) Growth hormone and bone. Hormone Research, 36 (Suppl. 1), 49-55.
    • (1991) Hormone Research , vol.36 , Issue.1 SUPPL. , pp. 49-55
    • Bouillon, R.1
  • 13
    • 0020606290 scopus 로고
    • Effects of growth hormone replacement therapy on 1,25-dihydroxyvitamin D and calcium metabolism
    • Burstein, S., Chen, I-W. & Tsang, R.C. (1983) Effects of growth hormone replacement therapy on 1,25-dihydroxyvitamin D and calcium metabolism. Journal of Clinical Endocrinology and Metabolism, 56, 1246-1251.
    • (1983) Journal of Clinical Endocrinology and Metabolism , vol.56 , pp. 1246-1251
    • Burstein, S.1    Chen, I.-W.2    Tsang, R.C.3
  • 14
    • 0021084195 scopus 로고
    • The hormonal and local regulation of bone formation
    • Canalis, E. (1983) The hormonal and local regulation of bone formation. Endocrine Reviews, 42, 62-77.
    • (1983) Endocrine Reviews , vol.42 , pp. 62-77
    • Canalis, E.1
  • 15
    • 0018949801 scopus 로고
    • Effect of growth hormone administration: Reciprocal changes in serum 1-25-dihydroxyvitamin D and intestinal calcium absorption
    • Chipman, J.J., Zerwekh, J., Nicar, M., Marks, J. & Pak, C.Y.C. (1980) Effect of growth hormone administration: reciprocal changes in serum 1-25-dihydroxyvitamin D and intestinal calcium absorption. Journal of Clinical Endocrinology and Metabolism, 51, 321-324.
    • (1980) Journal of Clinical Endocrinology and Metabolism , vol.51 , pp. 321-324
    • Chipman, J.J.1    Zerwekh, J.2    Nicar, M.3    Marks, J.4    Pak, C.Y.C.5
  • 20
    • 0028944463 scopus 로고
    • Clinical aspects of growth hormone deficiency in adults
    • De Boer, H., Blok, G-J. & van der Veen, E. A. (1995) Clinical aspects of growth hormone deficiency in adults. Endocrine Reviews, 16, 63-86.
    • (1995) Endocrine Reviews , vol.16 , pp. 63-86
    • De Boer, H.1    Blok, G.-J.2    Van Der Veen, E.A.3
  • 21
    • 0026724687 scopus 로고
    • Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism
    • Degerblad, M., Elgindy, N., Hall, K., Sjoberg, H.E. & Thorén, M. (1992) Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism. Acta Endocrinologica, 126, 387-393.
    • (1992) Acta Endocrinologica , vol.126 , pp. 387-393
    • Degerblad, M.1    Elgindy, N.2    Hall, K.3    Sjoberg, H.E.4    Thorén, M.5
  • 25
    • 0023832454 scopus 로고
    • Insulin-like growth factor I has independent effects on bone matrix formation and cell replication
    • Hock, J.M., Centrella, M. & Canalis, E. (1988) Insulin-like growth factor I has independent effects on bone matrix formation and cell replication. Endocrinology, 122, 254-260.
    • (1988) Endocrinology , vol.122 , pp. 254-260
    • Hock, J.M.1    Centrella, M.2    Canalis, E.3
  • 26
    • 0028146277 scopus 로고
    • Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women
    • Holloway, L., Butterfield, G., Hintz, R.L., Gesundheit, N. & Marcus, R. (1994) Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women. Journal of Clinical Endocrinology and Metabolism, 79, 470-479.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.79 , pp. 470-479
    • Holloway, L.1    Butterfield, G.2    Hintz, R.L.3    Gesundheit, N.4    Marcus, R.5
  • 31
    • 0027137137 scopus 로고
    • IGFs: Function and clinical importance 4 growth hormone, insuline-like growth factor I, and bone: clinical review
    • Johansson, A.J., Lindh, E. & Ljunghall, S. (1993) IGFs: function and clinical importance 4 growth hormone, insuline-like growth factor I, and bone: clinical review. Journal of Internal Medicine, 234, 553-560.
    • (1993) Journal of Internal Medicine , vol.234 , pp. 553-560
    • Johansson, A.J.1    Lindh, E.2    Ljunghall, S.3
  • 32
    • 0026014288 scopus 로고
    • Human growth hormone replacement therapy: Pharmalogical and clinical aspects
    • Jørgensen, J.O.L. (1991) Human growth hormone replacement therapy: Pharmalogical and clinical aspects. Endocrine Reviews, 12, 189-207.
    • (1991) Endocrine Reviews , vol.12 , pp. 189-207
    • Jørgensen, J.O.L.1
  • 34
    • 0027342405 scopus 로고
    • The newer uses of growth hormone in adults
    • Kaplan, S.L. (1993) The newer uses of growth hormone in adults. Advances in Internal Medicine, 38, 287-301.
    • (1993) Advances in Internal Medicine , vol.38 , pp. 287-301
    • Kaplan, S.L.1
  • 35
    • 0026590269 scopus 로고
    • Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset
    • Kaufman, J-M., Taelman, P., Vermeulen, A. & Vandeveghe, M. (1991) Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset. Journal of Clinical Endocrinology and Metabolism, 74, 118-123.
    • (1991) Journal of Clinical Endocrinology and Metabolism , vol.74 , pp. 118-123
    • Kaufman, J.-M.1    Taelman, P.2    Vermeulen, A.3    Vandeveghe, M.4
  • 40
    • 0025940870 scopus 로고
    • Bone density in adolescents
    • Ott, S.M. (1991) Bone density in adolescents. New England Journal of Medicine, 325, 1646-1647.
    • (1991) New England Journal of Medicine , vol.325 , pp. 1646-1647
    • Ott, S.M.1
  • 41
    • 0028261785 scopus 로고
    • Bone mass measurements: Reasons to be cautious
    • Ott, S.M. (1994) Bone mass measurements: reasons to be cautious. British Medical Journal, 308, 931-932.
    • (1994) British Medical Journal , vol.308 , pp. 931-932
    • Ott, S.M.1
  • 42
    • 0023869716 scopus 로고
    • Local and systemic factors in the pathogenesis of osteoporosis
    • Raisz, L.G. (1988) Local and systemic factors in the pathogenesis of osteoporosis. New England Journal of Medicine, 318, 818-828.
    • (1988) New England Journal of Medicine , vol.318 , pp. 818-828
    • Raisz, L.G.1
  • 44
    • 0027363782 scopus 로고
    • Reduced bone mineral content in adult patients with growth hormone deficiency
    • Rosen, T., Hansson, T., Granhed, H., Szucs, J. & Bengtsson, B-A. (1993) Reduced bone mineral content in adult patients with growth hormone deficiency. Acta Endocrinologica, 129, 201-206.
    • (1993) Acta Endocrinologica , vol.129 , pp. 201-206
    • Rosen, T.1    Hansson, T.2    Granhed, H.3    Szucs, J.4    Bengtsson, B.-A.5
  • 45
    • 0027521136 scopus 로고
    • Growth hormone replacement in adults: What dose?
    • Ross, R.J.M. (1993) Growth hormone replacement in adults: what dose? Clinical Endocrinology, 39, 401-402.
    • (1993) Clinical Endocrinology , vol.39 , pp. 401-402
    • Ross, R.J.M.1
  • 46
    • 0027550856 scopus 로고
    • Southwestern internal medicine conference: Growth hormone-aging and osteoporosis
    • Rubin, C.D. (1993) Southwestern internal medicine conference: growth hormone-aging and osteoporosis. American Journal of The Medical Sciences, 35, 120-129.
    • (1993) American Journal of the Medical Sciences , vol.35 , pp. 120-129
    • Rubin, C.D.1
  • 48
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon, F., Cuneo, R.C., Hesp, R. & Sonksen, P.H. (1989) The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. New England Journal of Medicine, 321, 1797-1803.
    • (1989) New England Journal of Medicine , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 50
    • 0027757005 scopus 로고
    • Growth hormone treatment in adults with GH deficiency: Effects on new biochemical markers of bone and collagen turnover
    • Sartorio, A., Conti, A., Monzani, M., Morabito, F. & Faglia, G. (1993) Growth hormone treatment in adults with GH deficiency: Effects on new biochemical markers of bone and collagen turnover. Journal of Endocrinological Investigation, 16, 893-898.
    • (1993) Journal of Endocrinological Investigation , vol.16 , pp. 893-898
    • Sartorio, A.1    Conti, A.2    Monzani, M.3    Morabito, F.4    Faglia, G.5
  • 53
    • 0026558570 scopus 로고
    • Osteoclast formation together with interleukin-6 production in mouse long bones is increased by insulin-like growth factor-I
    • Slootweg, M.C., Most, W.W., van Beck, E., Schot, L.P.C., Papopoulos, S.E. & Lowik, C.W.G.M. (1992) Osteoclast formation together with interleukin-6 production in mouse long bones is increased by insulin-like growth factor-I. Journal of Endocrinology, 132, 433-438.
    • (1992) Journal of Endocrinology , vol.132 , pp. 433-438
    • Slootweg, M.C.1    Most, W.W.2    Van Beck, E.3    Schot, L.P.C.4    Papopoulos, S.E.5    Lowik, C.W.G.M.6
  • 54
    • 0021250411 scopus 로고
    • Effect of growth hormone on osteoblasts and demonstration of somatomed-C/IGF-I in bone organ culture
    • Stracke, H., Schulz, A., Moeller, D., Rossol, S. & Schatz, H. (1984) Effect of growth hormone on osteoblasts and demonstration of somatomed-C/IGF-I in bone organ culture. Acta Endocrinologica, 107, 16-24.
    • (1984) Acta Endocrinologica , vol.107 , pp. 16-24
    • Stracke, H.1    Schulz, A.2    Moeller, D.3    Rossol, S.4    Schatz, H.5
  • 55
    • 0027284288 scopus 로고
    • Preliminary study of the effects of growth hormone substitution therapy on bone mineral density and serum osteocalcin levels in adults with growth hormone deficiency
    • Thoren, M., Soop, M., Degerblad, M & Saaf, M. (1993) Preliminary study of the effects of growth hormone substitution therapy on bone mineral density and serum osteocalcin levels in adults with growth hormone deficiency. Acta Endocrinologica, 128 (Suppl. 2), 41-43.
    • (1993) Acta Endocrinologica , vol.128 , Issue.2 SUPPL. , pp. 41-43
    • Thoren, M.1    Soop, M.2    Degerblad, M.3    Saaf, M.4
  • 58
    • 0025091097 scopus 로고
    • Growth hormone (replacement) therapy in adults: Bone and calcium metabolism
    • van der Veen, E.A. & Netelenbos, J.C. (1990) Growth hormone (replacement) therapy in adults: bone and calcium metabolism. Hormone Research, 33 (Suppl. 4), 65-68.
    • (1990) Hormone Research , vol.33 , Issue.4 SUPPL. , pp. 65-68
    • Van Der Veen, E.A.1    Netelenbos, J.C.2
  • 59
    • 0027519485 scopus 로고
    • Short and long-term effects of growth hormone treatment on bone turnover and bone mineral content in adult growth hormone-deficient males
    • Vandeweghe, M., Taelman, P. & Kaufman, J-M. (1993) Short and long-term effects of growth hormone treatment on bone turnover and bone mineral content in adult growth hormone-deficient males. Clinical Endocrinology, 39, 409-415.
    • (1993) Clinical Endocrinology , vol.39 , pp. 409-415
    • Vandeweghe, M.1    Taelman, P.2    Kaufman, J.-M.3
  • 60
    • 0027203108 scopus 로고
    • Growth hormone and bone metabolism
    • Wuster, C. (1993) Growth hormone and bone metabolism. Acta Endocrinologica, 128 (Suppl. 2), 14-18.
    • (1993) Acta Endocrinologica , vol.128 , Issue.2 SUPPL. , pp. 14-18
    • Wuster, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.