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Volumn 17, Issue 6, 1996, Pages 1273-1278

Antioxidants inhibit the enhancement of malignant cell transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; MANNITOL; METHYLNITRONITROSOGUANIDINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SCAVENGER; TUMOR PROMOTER;

EID: 0030011084     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.6.1273     Document Type: Article
Times cited : (23)

References (69)
  • 1
    • 0026425585 scopus 로고
    • Chemical and physical carcinogenesis: Advances and perspectives for the 1990s
    • Harris,C.C. (1991) Chemical and physical carcinogenesis: advances and perspectives for the 1990s. Cancer Res., 51, 5023-5044
    • (1991) Cancer Res. , vol.51 , pp. 5023-5044
    • Harris, C.C.1
  • 2
    • 0018932459 scopus 로고
    • Quantitalive evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine
    • Pilot,H.C., Goldsworthy,T., Campbell,H.A. and Poland,A. (1980) Quantitalive evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine. Cancer Res., 40, 3616-3620.
    • (1980) Cancer Res. , vol.40 , pp. 3616-3620
    • Pilot, H.C.1    Goldsworthy, T.2    Campbell, H.A.3    Poland, A.4
  • 3
    • 0023572151 scopus 로고
    • Promotion of C3H/10T1/2 morphological transformation by polychlori-nated dibenzo-p-dioxin isomers
    • Abernethy,D.J. and Boreiko,C.J. (1987) Promotion of C3H/10T1/2 morphological transformation by polychlori-nated dibenzo-p-dioxin isomers. Carcinogenesis (Lond.), 8, 1485-1490.
    • (1987) Carcinogenesis (Lond.) , vol.8 , pp. 1485-1490
    • Abernethy, D.J.1    Boreiko, C.J.2
  • 4
    • 0024413897 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin enhancement of N-methyl-N'-nitro-N-mtrosoguanidine-induced transformation of rat tracheal epithelial cells in culture
    • Tanaka,N., Nettesheim,P., Gray,T., Nelson,K. and Barrett,J.C. (1989) 2,3,7,8-Tetrachlorodibenzo-p-dioxin enhancement of N-methyl-N'-nitro-N-mtrosoguanidine-induced transformation of rat tracheal epithelial cells in culture. Cancer Res., 49, 2703-2708.
    • (1989) Cancer Res. , vol.49 , pp. 2703-2708
    • Tanaka, N.1    Nettesheim, P.2    Gray, T.3    Nelson, K.4    Barrett, J.C.5
  • 5
    • 0026694789 scopus 로고
    • Neoplastic transformation of immortalized human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Yang,J.-H., Thraves,P., Dritschilo,A. and Rhim,J.S. (1992) Neoplastic transformation of immortalized human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Res., 52, 3478-3482.
    • (1992) Cancer Res. , vol.52 , pp. 3478-3482
    • Yang, J.-H.1    Thraves, P.2    Dritschilo, A.3    Rhim, J.S.4
  • 6
    • 0017195657 scopus 로고
    • Tumorigenicity in vivo and induction of malignant transformation and mutagenicity in cell cultures by adriamycin and daunomycin
    • Marquardt,H., Philips,F.S. and Sternberg,S.S. (1976)Tumorigenicity in vivo and induction of malignant transformation and mutagenicity in cell cultures by adriamycin and daunomycin. Cancer Res., 36, 2065-2069.
    • (1976) Cancer Res. , vol.36 , pp. 2065-2069
    • Marquardt, H.1    Philips, F.S.2    Sternberg, S.S.3
  • 7
    • 0026093495 scopus 로고
    • An overview of the relationship between oxidative stress and chemical carcinogenesis
    • Trush,M.A. and Kensler,T.W. (1991) An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Rad. Biol. Med., 10, 201-209.
    • (1991) Free Rad. Biol. Med. , vol.10 , pp. 201-209
    • Trush, M.A.1    Kensler, T.W.2
  • 8
    • 0025976425 scopus 로고
    • Oxidant stress and carcinogenesis
    • Cerutti,P.A. (1991) Oxidant stress and carcinogenesis. Eur. Clin. Invest., 21, 1-5.
    • (1991) Eur. Clin. Invest. , vol.21 , pp. 1-5
    • Cerutti, P.A.1
  • 9
    • 0021894614 scopus 로고
    • The role of oxygen radicals as a possible mechanism of tumor promotion
    • Troll,W. and Wiesner,R. (1985) The role of oxygen radicals as a possible mechanism of tumor promotion. Ann. Rev. Pharmacol. Toxicol., 25, 509-528.
    • (1985) Ann. Rev. Pharmacol. Toxicol. , vol.25 , pp. 509-528
    • Troll, W.1    Wiesner, R.2
  • 10
    • 0023595278 scopus 로고
    • Peroxyl free radicals: Potential mediators of tumor initiation and promotion
    • Marnett,L.J. (1987) Peroxyl free radicals: potential mediators of tumor initiation and promotion. Carcinogenesis, 8, 1365-1373.
    • (1987) Carcinogenesis , vol.8 , pp. 1365-1373
    • Marnett, L.J.1
  • 11
    • 0021914668 scopus 로고
    • Phagocytes as carcinogens: Malignant transformation produced by human neutrophils
    • Weitzman,S.A., Weitberg,A.B., Clark,E.P. and Stossel,T.P. (1985) Phagocytes as carcinogens: Malignant transformation produced by human neutrophils. Science, 227, 1231-1233.
    • (1985) Science , vol.227 , pp. 1231-1233
    • Weitzman, S.A.1    Weitberg, A.B.2    Clark, E.P.3    Stossel, T.P.4
  • 12
    • 0026352795 scopus 로고
    • Free radicals in chemical carcionogenesis
    • Clemens,M.R. (1991) Free radicals in chemical carcionogenesis. Klin. Wochenschr., 69, 1123-1134.
    • (1991) Klin. Wochenschr. , vol.69 , pp. 1123-1134
    • Clemens, M.R.1
  • 13
    • 0023832886 scopus 로고
    • Phorbol ester induction of 8-lipoxygenase in inbred SENCAR (SSIN) but not C57B L/6J mice correlated with hyperplasia, edema, and oxidant generation but not ornithine decarboxylase induction
    • Fischer,S.M., Baldwin,J.K., Jasheway,D.W., Patrick,K.E. and Cameron,G.S. (1988) Phorbol ester induction of 8-lipoxygenase in inbred SENCAR (SSIN) but not C57B L/6J mice correlated with hyperplasia, edema, and oxidant generation but not ornithine decarboxylase induction. Cancer Res., 48, 658-664.
    • (1988) Cancer Res. , vol.48 , pp. 658-664
    • Fischer, S.M.1    Baldwin, J.K.2    Jasheway, D.W.3    Patrick, K.E.4    Cameron, G.S.5
  • 14
    • 0027153961 scopus 로고
    • Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters
    • Wei,H. and Frenkel,K. (1993) Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters. Carcinogenesis, 14, 1195-1201.
    • (1993) Carcinogenesis , vol.14 , pp. 1195-1201
    • Wei, H.1    Frenkel, K.2
  • 15
    • 0027318230 scopus 로고
    • Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage
    • Wei,L., Wei,H. and Frenkel,K. (1993) Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage. Carcinogenesis, 14, 841-847.
    • (1993) Carcinogenesis , vol.14 , pp. 841-847
    • Wei, L.1    Wei, H.2    Frenkel, K.3
  • 16
    • 0028937559 scopus 로고
    • Role of reactive oxygen in synthetic estrogen induction of hepatocellular carcinomas in rats and preventive effect of vitamins
    • Ogawa,T., Higashi,S., Kawarada,Y. and Mizumoto,R. (1995) Role of reactive oxygen in synthetic estrogen induction of hepatocellular carcinomas in rats and preventive effect of vitamins. Carcinogenesis, 16, 831-836.
    • (1995) Carcinogenesis , vol.16 , pp. 831-836
    • Ogawa, T.1    Higashi, S.2    Kawarada, Y.3    Mizumoto, R.4
  • 17
    • 0025169311 scopus 로고
    • Phenobarbital enhances the formation of reactive oxygen in neoplastic rat liver nodules
    • Scholz,W., Schütze,K., Kunz,W. and Schwarz,M. (1990) Phenobarbital enhances the formation of reactive oxygen in neoplastic rat liver nodules. Cancer Res., 50, 7015-7022.
    • (1990) Cancer Res. , vol.50 , pp. 7015-7022
    • Scholz, W.1    Schütze, K.2    Kunz, W.3    Schwarz, M.4
  • 19
    • 0025209997 scopus 로고
    • Dietary factors and risk of breast cancer: Combined analysis of 12 case-control studies
    • Howe,G.R. et al. (1990) Dietary factors and risk of breast cancer: combined analysis of 12 case-control studies. J. Natl Cancer Inst., 82, 561-569.
    • (1990) J. Natl Cancer Inst. , vol.82 , pp. 561-569
    • Howe, G.R.1
  • 21
    • 0027104622 scopus 로고
    • Vitamin C status and cancer: Epidemiologic evidence of reduced risk
    • Block,G. (1992) Vitamin C status and cancer: epidemiologic evidence of reduced risk. Ann. NY Acad. Sci., 669, 280-290.
    • (1992) Ann. NY Acad. Sci. , vol.669 , pp. 280-290
    • Block, G.1
  • 23
    • 0022362186 scopus 로고
    • Inhibitory effects of glutathione level-raising agents and D-α-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
    • Perchellet,J.-P., Owen,M.D., Posey,T.D., Orten,D.K. and Schneider,B.A. (1985) Inhibitory effects of glutathione level-raising agents and D-α-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 6, 567-573.
    • (1985) Carcinogenesis , vol.6 , pp. 567-573
    • Perchellet, J.-P.1    Owen, M.D.2    Posey, T.D.3    Orten, D.K.4    Schneider, B.A.5
  • 24
    • 0023589410 scopus 로고
    • Inhibition of 12-O-tetradecanoylphorbol-13-acetale induction of ornithine decarboxylase activity, DNA synthesis, and tumor promotion in mouse skin by ascorbic acid and ascorbyl palmitate
    • Smart,R.C., Huang,M.-T., Han,Z.T., Kaplan,M.C., Focella,A. and Conney,A.H. (1987) Inhibition of 12-O-tetradecanoylphorbol-13-acetale induction of ornithine decarboxylase activity, DNA synthesis, and tumor promotion in mouse skin by ascorbic acid and ascorbyl palmitate. Cancer Res., 47, 6633-6638.
    • (1987) Cancer Res. , vol.47 , pp. 6633-6638
    • Smart, R.C.1    Huang, M.-T.2    Han, Z.T.3    Kaplan, M.C.4    Focella, A.5    Conney, A.H.6
  • 25
    • 0027759783 scopus 로고
    • Inhibition of chrysarobin skin tumor promotion in SENCAR mice by antioxidants
    • Battalora,M.S.J., Kruszewski,F.H. and DiGiovanni,J. (1993) Inhibition of chrysarobin skin tumor promotion in SENCAR mice by antioxidants. Carcinogenesis, 14, 2507-2512.
    • (1993) Carcinogenesis , vol.14 , pp. 2507-2512
    • Battalora, M.S.J.1    Kruszewski, F.H.2    DiGiovanni, J.3
  • 26
    • 0024989693 scopus 로고
    • Differential mechanism for the inhibition of epidermal growth factor binding to its receptor on mouse keratinoytes by anthrones and phorbol esters
    • Imamoto,A., Beltrán,L.M. and DiGiovanni,J. (1990) Differential mechanism for the inhibition of epidermal growth factor binding to its receptor on mouse keratinoytes by anthrones and phorbol esters. Carcinogenesis, 11, 1543-1549.
    • (1990) Carcinogenesis , vol.11 , pp. 1543-1549
    • Imamoto, A.1    Beltrán, L.M.2    DiGiovanni, J.3
  • 27
    • 0002704973 scopus 로고
    • Studies on the mechanism of antitumor promoting agents: Suggestive evidence for the involvement of free radicals in promotion
    • Nygaard,O.F. and Simic,M.G. (eds.), Academic Press, New York
    • Slaga,T.J., Solanki,V. and Logani,M. (1983) Studies on the mechanism of antitumor promoting agents: suggestive evidence for the involvement of free radicals in promotion. In Nygaard,O.F. and Simic,M.G. (eds.), Radioprotectors and Anticarcinogens. Academic Press, New York, pp. 471-485.
    • (1983) Radioprotectors and Anticarcinogens , pp. 471-485
    • Slaga, T.J.1    Solanki, V.2    Logani, M.3
  • 28
    • 0027179061 scopus 로고
    • Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein
    • Wei,H., Wei,L., Fenkel,K., Bowen,R. and Barnes,S. (1993) Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr. Cancer, 20, 1-12.
    • (1993) Nutr. Cancer , vol.20 , pp. 1-12
    • Wei, H.1    Wei, L.2    Fenkel, K.3    Bowen, R.4    Barnes, S.5
  • 29
    • 0029036897 scopus 로고
    • The fatty acid bimodal action on superoxide anion production by human adherent monocytes under phorbol 12-myristate 13-acetate or diacylglycerol activation can be explained by the modulation of protein kinase C and p47 (phox) translocation
    • Kadrihassani,N., Leger,C.L. and Descomps,B. (1995) The fatty acid bimodal action on superoxide anion production by human adherent monocytes under phorbol 12-myristate 13-acetate or diacylglycerol activation can be explained by the modulation of protein kinase C and p47 (phox) translocation. J. Biol. Chem., 270, 15111-15118.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15111-15118
    • Kadrihassani, N.1    Leger, C.L.2    Descomps, B.3
  • 30
    • 0026648792 scopus 로고
    • Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1
    • Puga,A., Nebert,D.W. and Carrier,F. (1992) Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA Cell Biol., 11, 269-281.
    • (1992) DNA Cell Biol. , vol.11 , pp. 269-281
    • Puga, A.1    Nebert, D.W.2    Carrier, F.3
  • 31
    • 0027333084 scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on protein kinase C and inositol phosphate metabolism in primary cultures of rat hepatocytes
    • Wölfle,D., Schmutte,C. and Marquardt,H. (1993) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on protein kinase C and inositol phosphate metabolism in primary cultures of rat hepatocytes. Carcinogenesis, 14, 2283-2287.
    • (1993) Carcinogenesis , vol.14 , pp. 2283-2287
    • Wölfle, D.1    Schmutte, C.2    Marquardt, H.3
  • 32
    • 0024515086 scopus 로고
    • Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity
    • Moser,G.J. and Smart,R.C. (1989) Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis, 10, 851-856.
    • (1989) Carcinogenesis , vol.10 , pp. 851-856
    • Moser, G.J.1    Smart, R.C.2
  • 33
    • 0029069643 scopus 로고
    • The interaction between protein kinase C (PKC) and estrogens
    • Hahnel,R. and Gschwendt,M. (1995) The interaction between protein kinase C (PKC) and estrogens. Int. J. Oncol., 7, 11-16.
    • (1995) Int. J. Oncol. , vol.7 , pp. 11-16
    • Hahnel, R.1    Gschwendt, M.2
  • 34
    • 0028179722 scopus 로고
    • Quinone methide mediates in vitro induction of ornithine decarboxylase by the tumor promoter butylated hydroxy-toluene hydroperoxide
    • Guyton,K.Z., Dolan,P.M. and Kensler,T.W. (1994) Quinone methide mediates in vitro induction of ornithine decarboxylase by the tumor promoter butylated hydroxy-toluene hydroperoxide. Carcinogenesis, 15, 817-821.
    • (1994) Carcinogenesis , vol.15 , pp. 817-821
    • Guyton, K.Z.1    Dolan, P.M.2    Kensler, T.W.3
  • 35
    • 0024461627 scopus 로고
    • Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants
    • Larsson,R. and Cerutti,P. (1989) Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants. Cancer Res., 49, 5627-5632.
    • (1989) Cancer Res. , vol.49 , pp. 5627-5632
    • Larsson, R.1    Cerutti, P.2
  • 36
    • 0022806923 scopus 로고
    • Reversible expression of morphological transformation in C3H 10T1/2 mouse embryo cultures exposed to 12-O-tetradeca-noylphorbol-13-acetate
    • Sanchez,J.H., Abernethy,D.L. and Boreiko,C.J. (1986) Reversible expression of morphological transformation in C3H 10T1/2 mouse embryo cultures exposed to 12-O-tetradeca-noylphorbol-13-acetate. Carcinogenesis, 7, 1793-1796.
    • (1986) Carcinogenesis , vol.7 , pp. 1793-1796
    • Sanchez, J.H.1    Abernethy, D.L.2    Boreiko, C.J.3
  • 37
    • 0025266560 scopus 로고
    • Vasopressin and norepinephrine stimulation of inositol phosphate accumulation in rat hepatocytes are modified differently by protein kinase C and protein kinase A
    • Pittner,A.R. and Fain,J.N. (1990) Vasopressin and norepinephrine stimulation of inositol phosphate accumulation in rat hepatocytes are modified differently by protein kinase C and protein kinase A. Biochim. Biophys. Acta, 1043, 211-217.
    • (1990) Biochim. Biophys. Acta , vol.1043 , pp. 211-217
    • Pittner, A.R.1    Fain, J.N.2
  • 38
    • 0020643221 scopus 로고
    • Calcium-activated, phospholipid-dependent protein kinase (protein kinase C) from rat brain
    • Kikkawa,U., Minakuchi,R., Takai,Y. and Nishizuka,Y. (1983) Calcium-activated, phospholipid-dependent protein kinase (protein kinase C) from rat brain. Methods Enzymol., 99, 288-298.
    • (1983) Methods Enzymol. , vol.99 , pp. 288-298
    • Kikkawa, U.1    Minakuchi, R.2    Takai, Y.3    Nishizuka, Y.4
  • 39
    • 0022454807 scopus 로고
    • The antioxidant efficiency of vitamin C is concentration-dependent
    • Wayner,D.D.M., Burton,G.W. and Ingold,K.U. (1986) The antioxidant efficiency of vitamin C is concentration-dependent. Biochim. Biophys. Acta, 884, 119-123.
    • (1986) Biochim. Biophys. Acta , vol.884 , pp. 119-123
    • Wayner, D.D.M.1    Burton, G.W.2    Ingold, K.U.3
  • 40
    • 0027213625 scopus 로고
    • Tocopherol-mediated peroxidation. the prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein
    • Bowry,V.W. and Stocker,R. (1993) Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein. J. Am. Chem. Soc., 115, 6029-6044.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 6029-6044
    • Bowry, V.W.1    Stocker, R.2
  • 41
    • 0025015082 scopus 로고
    • Effects of activators and inhibitors of protein kinase C on two-stage transformation in BALB/3T3 cells
    • Semba,M. and Inui,N. (1990) Effects of activators and inhibitors of protein kinase C on two-stage transformation in BALB/3T3 cells. Toxicol. Lett., 51, 7-12.
    • (1990) Toxicol. Lett. , vol.51 , pp. 7-12
    • Semba, M.1    Inui, N.2
  • 42
    • 0024240956 scopus 로고
    • Inhibition of phorbol ester-caused induction of ornithine decarboxylase and tumor promotion in mouse skin by staurosporine, a potent inhibitor of protein kinase C
    • Yamada,S., Hirota,K., Chida,K. and Kuroki,T. (1988) Inhibition of phorbol ester-caused induction of ornithine decarboxylase and tumor promotion in mouse skin by staurosporine, a potent inhibitor of protein kinase C. Biochem. Biophys. Res. Commun., 157, 9-15.
    • (1988) Biochem. Biophys. Res. Commun. , vol.157 , pp. 9-15
    • Yamada, S.1    Hirota, K.2    Chida, K.3    Kuroki, T.4
  • 43
    • 0020425524 scopus 로고
    • Tumor promotion by TCDD in skin of HRS/J hairless mice
    • Poland,A., Palen,D. and Glover,E. (1982) Tumor promotion by TCDD in skin of HRS/J hairless mice. Nature, 300, 271-273.
    • (1982) Nature , vol.300 , pp. 271-273
    • Poland, A.1    Palen, D.2    Glover, E.3
  • 44
    • 2342435355 scopus 로고
    • Assessment of the cytotoxic and tumor promoting potential of 2,3,7,8-TCDD and PCB congeners in vitro: Comparison of in vitro and in vivo data
    • Wölfle,D., Kähler,A. and Marquardt,H. (1995) Assessment of the cytotoxic and tumor promoting potential of 2,3,7,8-TCDD and PCB congeners in vitro: comparison of in vitro and in vivo data. Organohalogen Compounds, 25, 195-198.
    • (1995) Organohalogen Compounds , vol.25 , pp. 195-198
    • Wölfle, D.1    Kähler, A.2    Marquardt, H.3
  • 45
    • 0027193335 scopus 로고
    • Growth stimulation of primary rat hepatocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Wölfle,D., Becker,E. and Schmutte,C. (1993) Growth stimulation of primary rat hepatocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cell Biol. Toxicol., 9, 15-31.
    • (1993) Cell Biol. Toxicol. , vol.9 , pp. 15-31
    • Wölfle, D.1    Becker, E.2    Schmutte, C.3
  • 46
    • 0026550571 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin and ethinyl-estradiol as co-mitogens in cultured rat hepatocytes
    • Schrenk,D., Krager,A., Lipp,H.-P. and Bock,K.W. (1992) 2,3,7,8-Tetrachlorodibenzo-p-dioxin and ethinyl-estradiol as co-mitogens in cultured rat hepatocytes. Carcinogenesis, 13, 453-456.
    • (1992) Carcinogenesis , vol.13 , pp. 453-456
    • Schrenk, D.1    Krager, A.2    Lipp, H.-P.3    Bock, K.W.4
  • 47
    • 0021926833 scopus 로고
    • Role of reactive oxygen in tumor promotion: Implication of Superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA
    • Nakamura,Y., Colburn,N.H. and Gindhart,T.D. (1985) Role of reactive oxygen in tumor promotion: implication of Superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA. Carcinogenesis, 6, 229-235.
    • (1985) Carcinogenesis , vol.6 , pp. 229-235
    • Nakamura, Y.1    Colburn, N.H.2    Gindhart, T.D.3
  • 48
    • 0023228176 scopus 로고
    • Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by radical scavengers
    • Saito,M., Tanaka,N., Ohkawa,Y. and Inui,N. (1987) Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by radical scavengers. Cancer Lett., 35, 167-171.
    • (1987) Cancer Lett. , vol.35 , pp. 167-171
    • Saito, M.1    Tanaka, N.2    Ohkawa, Y.3    Inui, N.4
  • 49
    • 0019801387 scopus 로고
    • Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promoters
    • Solanki,V., Rana,R.S. and Slaga,T.J. (1981) Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promoters. Carcinogenesis, 2, 1141 -1146.
    • (1981) Carcinogenesis , vol.2 , pp. 1141-1146
    • Solanki, V.1    Rana, R.S.2    Slaga, T.J.3
  • 50
    • 0025360652 scopus 로고
    • Modulation of catalase activities in murine epidermal cells as a function of differentiation and exposure to 12-O-tetradecanoylphorbol-13-acetate
    • Reiners,J.J.,Jr., Thai,G., Pavone,A., Rupp,T. and Kodari,E. (1990) Modulation of catalase activities in murine epidermal cells as a function of differentiation and exposure to 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 11, 957-963.
    • (1990) Carcinogenesis , vol.11 , pp. 957-963
    • Reiners Jr., J.J.1    Thai, G.2    Pavone, A.3    Rupp, T.4    Kodari, E.5
  • 51
    • 0024210232 scopus 로고
    • Phorbol ester tumor promoters and multistage skin carcinogenesis
    • Perchellet,J.P. and Perchellet,E.M. (1988) Phorbol ester tumor promoters and multistage skin carcinogenesis. ISI Atlas of Science: Pharmacol., 2, 325-333.
    • (1988) ISI Atlas of Science: Pharmacol. , vol.2 , pp. 325-333
    • Perchellet, J.P.1    Perchellet, E.M.2
  • 52
    • 0025155746 scopus 로고
    • Genetic modulation of the cellular antioxidant defence capacity
    • Amstad,P. and Cerutti,P. (1990) Genetic modulation of the cellular antioxidant defence capacity. Environ. Health Perspect., 88, 77-82.
    • (1990) Environ. Health Perspect. , vol.88 , pp. 77-82
    • Amstad, P.1    Cerutti, P.2
  • 53
    • 0022456099 scopus 로고
    • Enhanced expression of c-myc and decreased expression of c-fos protooncogenes in chemically and radiation-transformed C3H 10T1/2 Cl 8 mouse embryo cell lines
    • Shuin,T., Billings,P., Lillehaug,J., Patierno,S., Roy-Burman,P. and Landolph,J. (1986) Enhanced expression of c-myc and decreased expression of c-fos protooncogenes in chemically and radiation-transformed C3H 10T1/2 Cl 8 mouse embryo cell lines. Cancer Res., 46, 5302-5311.
    • (1986) Cancer Res. , vol.46 , pp. 5302-5311
    • Shuin, T.1    Billings, P.2    Lillehaug, J.3    Patierno, S.4    Roy-Burman, P.5    Landolph, J.6
  • 55
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J., 12, 2005-2015.
    • (1993) EMBO J. , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 56
    • 46149139817 scopus 로고
    • Peroxisome proliferators and cancer: Mechanisms and implications
    • Reddy,J.K. and Rao,M.S. (1986) Peroxisome proliferators and cancer: mechanisms and implications. TIPS, 11, 438-441.
    • (1986) TIPS , vol.11 , pp. 438-441
    • Reddy, J.K.1    Rao, M.S.2
  • 57
    • 0028237181 scopus 로고
    • DNA damage caused by reactive oxygen species originating from a copper-dependent oxidation of the 2-hydroxy catechol of estradiol
    • Li,Y., Trush,M.A. and Yager,J.D. (1994) DNA damage caused by reactive oxygen species originating from a copper-dependent oxidation of the 2-hydroxy catechol of estradiol. Carcinogenesis, 15, 1421-1427.
    • (1994) Carcinogenesis , vol.15 , pp. 1421-1427
    • Li, Y.1    Trush, M.A.2    Yager, J.D.3
  • 58
    • 0027245551 scopus 로고
    • Comparative studies on lipid peroxidation and DNA-single strand breaks induced by lindane, DDT, chlordane and endrin in rats
    • Hassoun,E., Bagchi,M., Bagchi,D. and Strohs,S.J. (1993) Comparative studies on lipid peroxidation and DNA-single strand breaks induced by lindane, DDT, chlordane and endrin in rats. Comp. Biochem. Physiol., 104C, 427-431.
    • (1993) Comp. Biochem. Physiol. , vol.104 C , pp. 427-431
    • Hassoun, E.1    Bagchi, M.2    Bagchi, D.3    Strohs, S.J.4
  • 59
    • 0026499853 scopus 로고
    • Induction of 8-hydroxydeoxyguanosine in Ah-responsive mouse liver by iron and Aroclor 1254
    • Faux,S.P., Francis,J.E., Smith,A.G. and Chipman,J.K. (1992) Induction of 8-hydroxydeoxyguanosine in Ah-responsive mouse liver by iron and Aroclor 1254. Carcinogenesis, 13, 247-250.
    • (1992) Carcinogenesis , vol.13 , pp. 247-250
    • Faux, S.P.1    Francis, J.E.2    Smith, A.G.3    Chipman, J.K.4
  • 63
    • 0026758341 scopus 로고
    • Expression of platelet-derived growth factor-independent phenotypes in BALB/c 3T3 cell variant with high susceptibility to chemically or physically induced neoplastic cell transformation: Dissociation from activation of protein kinase C
    • Tatsuka,M., Owada,M.K. and Mitsui,H. (1992) Expression of platelet-derived growth factor-independent phenotypes in BALB/c 3T3 cell variant with high susceptibility to chemically or physically induced neoplastic cell transformation: dissociation from activation of protein kinase C. Cancer Res., 52, 4232-4241.
    • (1992) Cancer Res. , vol.52 , pp. 4232-4241
    • Tatsuka, M.1    Owada, M.K.2    Mitsui, H.3
  • 64
    • 0024339594 scopus 로고
    • Disturbances in growth control and gene expression in a C3H/10T1/2 cell line that stably overproduces protein kinase C
    • Krauss,R.S., Housey,G.M., Johnson,M.D. and Weinstein,I.B. (1989) Disturbances in growth control and gene expression in a C3H/10T1/2 cell line that stably overproduces protein kinase C. Oncogene, 4, 991-998.
    • (1989) Oncogene , vol.4 , pp. 991-998
    • Krauss, R.S.1    Housey, G.M.2    Johnson, M.D.3    Weinstein, I.B.4
  • 65
    • 0025330085 scopus 로고
    • Protein kinase C is localized in focal contacts of normal but not transformed fibroblasts
    • Hyatt,S.L., Klauck,T. and Jaken,S. (1990) Protein kinase C is localized in focal contacts of normal but not transformed fibroblasts. Mol. Carcinogenesis, 3, 45-53.
    • (1990) Mol. Carcinogenesis , vol.3 , pp. 45-53
    • Hyatt, S.L.1    Klauck, T.2    Jaken, S.3
  • 66
    • 0027991782 scopus 로고
    • Membrane and nuclear protein kinase C activation in the early stages of diethylnitrosamine-induced rat hepatocarcinogenesis
    • LaPorta,C.A.M. and Comolli,R. (1994) Membrane and nuclear protein kinase C activation in the early stages of diethylnitrosamine-induced rat hepatocarcinogenesis. Carcinogenesis, 15, 1743-1747.
    • (1994) Carcinogenesis , vol.15 , pp. 1743-1747
    • LaPorta, C.A.M.1    Comolli, R.2
  • 67
    • 0029028553 scopus 로고
    • Over-expression of protein kinase C is associated with a delay in preneoplastic lesion development in diethylnitrosamine-induced rat hepatocarcinogenesis
    • LaPorta,C.A.M. and Comolli,R. (1995) Over-expression of protein kinase C is associated with a delay in preneoplastic lesion development in diethylnitrosamine-induced rat hepatocarcinogenesis. Carcinogenesis, 16, 1233-1238.
    • (1995) Carcinogenesis , vol.16 , pp. 1233-1238
    • LaPorta, C.A.M.1    Comolli, R.2
  • 68
    • 0025981422 scopus 로고
    • The differential expression of protein kinase C genes in normal human neonatal melanocytes and metastatic melanomas
    • Yamanishi,D.T., Graham,M., Buckmeier,J.A. and Meyskens,F.L.,Jr. (1991) The differential expression of protein kinase C genes in normal human neonatal melanocytes and metastatic melanomas. Carcinogenesis, 12, 105-109.
    • (1991) Carcinogenesis , vol.12 , pp. 105-109
    • Yamanishi, D.T.1    Graham, M.2    Buckmeier, J.A.3    Meyskens Jr., F.L.4
  • 69
    • 0023550584 scopus 로고
    • Effects of tumor-promoting agents 12-O-tetradecanoylphorbol-13-acetate and phenobarbital on DNA synthesis of rat hepatocytes in primary culture
    • Sawada,N., Staecker,R.J. and Pitot,H.C. (1987) Effects of tumor-promoting agents 12-O-tetradecanoylphorbol-13-acetate and phenobarbital on DNA synthesis of rat hepatocytes in primary culture. Cancer Res., 47, 5665-5671.
    • (1987) Cancer Res. , vol.47 , pp. 5665-5671
    • Sawada, N.1    Staecker, R.J.2    Pitot, H.C.3


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