Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli

European Journal of Neuroscience

Volumn 8, Issue 7, 1996, Pages 1479-1487

  Wilkinson, Lawrence S ^a   Humby, Trevor ^a,b   Killcross, Simon ^a   Robbins, Trevor W ^a   Everitt, Barry J ^a  

^a UK   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

5 hydroxytryptamine; Conditioning; Context; Hippocampus; Microdialysis

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; AUDITORY STIMULATION; AVERSION; CONDITIONED REFLEX; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE; SHOCK; VISUAL STIMULATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ACOUSTIC STIMULATION; ANIMALS; AVOIDANCE LEARNING; CALCIUM; CONDITIONING, CLASSICAL; CUES; ELECTROSHOCK; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; MALE; MEMBRANE POTENTIALS; MICRODIALYSIS; RATS; RATS, INBRED STRAINS; SEROTONIN;

EID: 0030010708     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01610.x     Document Type: Article

References (27)

1. Boutelle, M. G., Zetterstrom, T., Pei, Q., Svensson, L. and Fillenz, M. (1990) In vivo neurochemical effects of tail pinch. J. Neurosci. Methods, 34, 151-157.
2. Charney, D. S., Heninger, G. R., Renhard, J. F., Sternberg, D. E. and Hafstead, K. M. (1982) Effect of intravenous L-tryptophan on prolactin and growth hormone and mood in healthy subjects. Psychopharmacology, 77, 217-222.
3. Critchley, M. A. E., Njung'e, K. and Handley, S. L. (1992) Actions and some interactions of some 5HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions. Psychopharmacology, 106, 484-490.
4. Deakin, J. F. W. (1992) Amine mechanisms in anxiety and depression. In Elliot, J. M., Heal, D. J. and Marsden, C. A. (eds). Experimental Approaches to Anxiety and Depression. Wiley, Chichester, pp. 233-243.
5. Good, M. and Honey, R. (1991) Conditioning and contextual retrieval in hippocampal rats. Behav. Neurosci., 105, 499-509.
6. Graeff, F. G., Zuardi, A. W., Gjimiglio, J. S., Filho, E. C. and Karniol, I. G. (1985) Effect of metergoline on human anxiety. Psychopharmacotogy, 86, 334-338.
7. Graham, S., Ho, M. Y., Bradshaw, C. M. and Szabadi, E. (1994) Facilitated acquisition of a temporal discrimination following destruction of the ascending 5-hydroxytryptaminergic pathways. Psychopharmacology, 116, 373-378.
8. Gray, J. A. (1987) The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-hippocampal System. Oxford University Press, Oxford.
9. Guevara-Guzman, R., Emson, P. C. and Kendrick, K. M. (1994) Modulation of in vivo transmitter release by nitric oxide and cyclic GMP. J. Neurochem., 62, 807-810.
10. Handley, S. L. and McBlane, J. W. (1993) 5HT drugs in animal models of anxiety. Psychopharmacology, 112, 13-20.
11. Handley, S. L., McBlane, J. W., Critchley, M. A. E. and Njung'e, K. (1993) Multiple serotonin mechanisms in animal models of anxiety: environmental and cognitive factors. Behav. Brain Res., 58, 203-210.
12. Harrison, A. A., Muir, J. L., Robbins, T. W., Everitt, B. J. and Wilkinson, L. S. (1992) The effects of forebrain 5HT depletion on visual attention performance in the rat. J. Pharmacol., A59. Proceedings of the British Association for Psychopharmacology, Cambridge, UK.
13. Howell, D. C. (1989), Chapter 11. In Statistical Methods For Psychology. Duxberry Press, Belmont, CA, pp. 314 ff.
14. Iversen, S. D. (1984) 5-HT and anxiety. Neuropharmacology, 23, 1553-1560.
15. Jacobs, B. L. and Azmitia, E. C. (1992) Structure and function of the brain serotonin system. Physiol. Rev., 72, 165-230.
16. Jackson, S. R., Marrocco, R. and Posner, M. I. (1994) Networks of anatomical areas controlling visuospatial attention. Neural Networks, 7, 925-944.
17. Lorens, S. A. (1978) Some behavioural effects of serotonin depletion depend on method: a comparison of 5,7-dihydroxytryptamine, p-chlorophenylalanine, p-chloroamphetamine and electrolytic raphe lesions. Ann. N.Y. Acad. Sci., 305, 522-555.
18. Marlin, N. A. (1980) Contextual associations in trace conditioning. Anim. Learn. Behav., 9, 519-523.
19. Marrocco, R. T., Witte, E. A.. and Davidson, M. C. (I994) Arousal systems. Curr. Opin. Neurobiol., 4, 166-170.
20. Nomikos, G. G., Arborelius, L. and Svensson, T. H. (1992) The novel 5HT1A receptor antagonist (S)-UH-301 prevents (R)-8-OH-DPAT-induced decrease in interstitial concentrations of serotonin in the rat hippocampus. Eur. J. Pharmacol., 216, 373-378.
21. O'Keefe, J. M. and Nadel, L. (1978) The Hippocampus as a Cognitive Map. Clarendon Press, Oxford.
22. Paxinos, G. and Watson. C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, London.
23. Pei, Q., Zetterstrom, T. and Fillenz, M. (1990) Tail pinch-induced changes in the turnover and release of dopamine and 5-hydroxytryptamine in different brain regions of the rat. Neuroscience, 35, 133-138.
24. Pellow, S., Johnston, A. and File, S. E. (1987) Selective agonists and antagonists for 5-hydroxytryptamine receptor subtypes and interactions with yohimbine and FG7142 using the elevated plus-maze test in the rat. J. Pharm. Pharmacol., 39, 917-928.
25. Phillips, R. G. and LeDoux, J. E. (1992) Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav. Neurosci., 106, 274-285.
26. Phillips, R. G. and LeDoux, J. E. (1994) Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. Learning Memory, 1, 34-44.
27. Routledge, C., Gurling, J., Wright, I. K. and Dourish, C. T. (1993) Neurochemical profile of the selective and silent 5-HT1A receptor antagonist WAY 100135: an in vivo microdialysis study. Eur. J. Pharmacol., 239, 195-202.