β-Amyloid increases enzyme activity and protein levels of glutamine synthetase in cultured astrocytes

Experimental Neurology

Volumn 139, Issue 1, 1996, Pages 167-171

  Pike, Christian J ^a   Ramezan Arab, Nima ^a   Miller, Stephan ^a   Cotman, Carl W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GLUTAMATE AMMONIA LIGASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030010544     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.0091     Document Type: Article

References (39)

1. ARAUJO, D. M., AND C. W. COTMAN. 1992. β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Res. 569: 141-145.
2. BEHL, C., J. B. DAVIS, R. LESLEY, AND D. SCHUBERT. 1994. Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77: 817-827.
3. BURDICK, D., B. SOREGHAN, M. KWON, J. KOSMOSKI, M. KNAUER, A. HENSCHEN, J. YATES, C. COTMAN, AND C. GLABE. 1992. Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J. Biol. Chem. 267: 546-554.
4. CANNING, D. R., R. J. MCKEON, D. A. DEWITT, G. PERRY, J. R. WUJEK, R. C. A. FREDERICKSON, AND J. SILVER. 1993. β-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth. Exp. Neurol. 124: 289-298.
5. CHOI, D. W. 1988. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623-634.
6. COTMAN, C. W., C. J. PIKE, AND B. J. CUMMINGS. 1993. Adaptive versus pathological plasticity: Possible contributions to agerelated dementia. Adv. Neurol. 59: 35-45.
7. COYLE, J. T., AND P. PUTTFARCKEN. 1993. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695.
8. DICKSON, D. W., J. FARLO, P. DAVIES, H. CRYSTAL, P. FULD, AND S. C. YEN. 1988. A double-labeling immunohistochemical study of senile plaques. Am. J. Pathol. 132: 86-101.
9. EDDLESTON, M., AND L. MUCKE. 1993. Molecular profile of reactive astrocytes - Implications for their role in neurologic disease. Neuroscience 54: 15-36.
10. GÓMEZ-PINILLA, F., B. J. CUMMINGS, AND C. W. COTMAN. 1990. Induction of basic fibroblast growth factor in Alzheimer's disease pathology. NeuroReport 1: 211-214.
11. HARRIS, M. E., K. HENSLEY, D. A. BUTTERFIELD, R. A. LEEDLE, AND J. M. CARNEY. 1995. Direct evidence of oxidative injury produced by the Alzheimer's β-amyloid peptide (1-40) in cultured hippocampal neurons. Exp. Neurol. 131: 193-202.
12. HENSLEY, K., J. M. CARNEY, M. P. MATTSON, M. AKSENOVA, M. HARRIS, J. F. WU, R. A. FLOYD, AND D. A. BUTTERFIELD. 1994. A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer's disease. Proc. Natl. Acad. Sci. USA 91: 3270-3274.
13. HÖKE, A., D. R. CANNING, C. J. MALEMUD, AND J. SILVER. 1994. Regional differences in reactive gliosis induced by substrate-bound β-amyloid. Exp. Neurol. 130: 56-66.
14. JØRGENSEN, O. S., B. W. BROOKSBANK, AND R. BALÁZS. 1990. Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease. J. Neurol. Sci. 98: 63-79.
15. KOH, J.-Y., AND D. W. CHOI. 1987. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods 20: 83-90.
16. KOH, J.-Y., L. L. YANG, AND C. W. COTMAN. 1990. β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533: 315-320.
17. LEVINE, R. L., C. N. OLIVER, R. M. FULKS, AND E. R. STADTMAN. 1981. Turnover of bacterial glutamine synthtase: Oxidative inactivation precedes proteolysis. Proc. Natl. Acad. Sci. USA 78: 2120-2124.
18. 25-35 peptide-mediated neurotoxicity in rat hippocampal cultures. J. Neurosci. Res. 39: 494-505.
19. MANDYBUR, T. I., AND C. C. CHUIRAZZI. 1990. Astrocytes and the plaques of Alzheimer's disease. Neurology 40: 635-639.
20. MARTINEZ-HERNANDEZ, A., K. P. BELL, AND M. D. NORENBERG. 1976. Glutamine synthetase: Glial localization in brain. Science 195: 1356-1358.
21. MATTSON, M. P., B. CHENG, D. DAVIS, K. BRYANT, I. LEIEBERBURG, AND R. RYDEL. 1992. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12: 376-389.
22. MATTSON, M. P., M. MURRAIN, P. B. GUTHRIE, AND S. B. KATER. 1989. Fibroblast growth factor and glutamate: Opposing roles in the generation and degeneration of hippocampal architecture. J. Neurosci. 9: 3728-3740.
23. MEISTER, A. 1985. Glutamine synthetase from mammalian tissues. Methods Enzymol. 113: 185-199.
24. MILLER, S., P. B. NUNN, AND R. J. BRIDGES. 1993. Induction of astrocyte glutamine synthetase activity by the Lathyrus toxin β-N-oxalyl-L-alpha, β-diaminopropionic acid (β-L-ODAP). Glia 7: 329-336.
25. NORENBERG, M. D. 1982. Immunohistochemical study of glutamine synthetase in brain trauma. J. Neuropathol. Exp. Neurol. 41: 347.
26. OROPEZA, R. L., H. WEKERLE, AND Z. WERB. 1987. Expression of apolipoprotein E by mouse brain astrocytes and its modulation by interferon-gamma. Brain Res. 410: 45-51.
27. 1-antichymotrypsin mRNA. Am. J. Pathol. 135: 827-834.
28. PETITO, C. K., M. C. CHUNG, L. M. VERKHOVSKY, AND A. J. COOPER. 1992. Brain glutamine synthetase increases following cerebral ischemia in the rat. Brain Res. 569: 275-280.
29. PIKE, C. J., B. J. CUMMINGS, AND C. W. COTMAN. 1995. Contributions of β-amyloid to reactive astrocytosis in Alzheimer's disease. Pages 619-627 in K. Iqbal, J. Mortimer, B. Winblad, and H. Wisniewski, Eds., Research Advances in Alzheimer's Disease and Related Disorders. Wiley, Sussex, England.
30. PIKE, C. J., B. J. CUMMINGS, AND C. W. COTMAN. 1995. Early association of reactive astrocytes with senile plaques in Alzheimer's disease. Exp. Neurol. 132: 172-179.
31. PIKE, C. J., B. J. CUMMINGS, R. MONZAVI, AND C. W. COTMAN. 1994. β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience 63: 517-531.
32. SANDBERG, M., H. K. WARD, AND H. F. BRADFORD. 1985. Effect of corticostriate pathway lesion on the activities of enzymes involved in synthesis and metabolism of amino acid neurotransmitters in the striatum. J. Neurochem. 44: 42-47.
33. SMITH, C. D., J. M. CARNEY, P. E. STARKE-REED, C. N. OLIVER, E. R. STADTMAN, R. A. FLOYD, AND W. R. MARKESBERY. 1991. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer's disease. Proc. Natl. Acad. Sci. USA 88: 10540-10543.
34. SMITH, M. A., L. M. SAYRE, V. M. MONNIER, AND G. PERRY. 1995. Radical AGEing in Alzheimer's disease. Trends Neurosci. 18: 172-176.
35. STOPA, E. G., A.-M. GONZALEZ, R. CHORSKY, R. J. CORONA, J. ALVAREZ, E. D. BIRD, AND A. BAIRD. 1990. Basic fibroblast growth factor in Alzheimer's disease. Biochem. Biophys. Res. Commun. 171: 690-696.
36. TANAKA, H., M. ARAKI, AND T. MASUZAWA. 1992. Reaction of astrocytes in the gerbil hippocampus following transient ischemia: immunohistochemical observations with antibodies against glial fibrillary acidic protein, glutamine synthetase, and S-100 protein. Exp. Neurol. 116: 264-274.
37. VOLICER, L., AND P. B. CRINO. 1990. Involvement of free radicals in dementia of the Alzheimer's type: A hypothesis. Neurobiol. Aging 11: 567-571.
38. WISNIEWSKI, H. M., AND R. D. TERRY. 1973. Reexamination of the pathogenesis of the senile plaque. Pages 1-26 in H. M. Zimmerman, Ed., Progress in Neuropathology Grune & Stratton, New York.
39. WU, D. K., S. SCULLY, AND J. DE VELLIS. 1988. Induction of glutamine synthetase in rat astrocytes by co-cultivation with embryonic chick neurons. J. Neurochem. 50: 929-935.