Combinatorial chemistry: A rational approach to chemical diversity

European Journal of Medicinal Chemistry

Volumn 31, Issue 2, 1996, Pages 87-98

  Williard, X ^a   Pop, I ^a   Bourel, L ^a   Horvath, D ^a   Baudelle, R ^a   Melnyk, P ^a   Deprez B ^a   Tartar, A ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Combinatorial synthesis; Diversity; Library; Medicinal chemistry

Indexed keywords

DRUG DESIGN; DRUG MIXTURE; DRUG RESEARCH; DRUG SYNTHESIS; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0030010430     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)80441-7     Document Type: Review

References (36)

1. Gordon EM, Barrett RW, Dower WJ, Fodor SPA, Gallop MA (1994) J Med Chem 37, 1385-1401
2. Gallop MA, Barrett RW, Dower WJ, Fodor SPA, Gordon EM (1994) J Med Chem 37, 1233-1251
3. Merrifield RB (1963) J Am Chem Soc 85, 2149-2154
4. Ecker DJ, Crooke ST (1995) Biotechnology 13, 351-360
5. Smith PW, Lai JYQ, Whittington AR et al (1994) Bioorg Med Chem Lett 4, 2821-2824
6. Zuckermann RN, Kerr JM, Kent SBH, Moos WH (1992) J Am Chem Soc 114, 10646-10647
7. Cho CY, Moran EJ, Cherry SR et al (1993) Science 261, 1303-1305
8. Smith AB, Keenan TP, Holcomb RC et al (1992) J Am Chem Soc 114, 10672-10674
9. Patek M, Drake B, Lebl M (1994) Tetrahedron Lett 35, 9169-9172
10. Hobbs de Witt S, Kiely JS, Stankovic CJ, Schroeder MC, Reynolds Cody DM, Pavia MR (1993) Proc Natl Acad Sci USA 90, 6909-6913
11. Rano TA, Chapman KT (1995) Tetrahedron Lett 36, 3789-3792
12. Chen C, Ahlbergrandall LA, Miller RB, Jones AD, Kurth MJ (1994) J Am Chem Soc 116, 2661-2662
13. Backes BJ, Ellman JA, (1994) J Am Chem Soc 116, 11171-11172
14. Frenette R, Friesen RW (1994) Tetrahedron Lett 35, 9177-9180
15. Zuckerman RN, Martin EJ, Spellmeyer DC et al (1994) J Med Chem 37, 2678-2685
16. Houghten RA, Appel JR, Blondelle SE, Cuervo JH, Dooley CT, Pinilla C (1992) Biotechniques 13, 412-431
17. Houghten RA, Dooley CT (1993) Biorg Med Chem Lett 3, 405-412
18. Dooley CT, Chung NN, Schiller PW, Houghten RA (1993) Proc Natl Acad Sci USA 90, 10811-10815
19. Pinilla C, Appel JR, Blanc P, Houghten RA (1992) Biotechniques 13, 901-905
20. Dooley CT, Houghten RA (1993) Life Sci 52, 1509-1517
21. Ostresh JM, Husar GM, Blondelle SE, Weber PA, Houghten RA (1994) Proc Natl Acad Sci USA 91, 11138-11142
22. Déprez B, Williard X, Bourel L, Coste H, Hyafil F, Tartar A (1995) J Am Chem Soc 117, 5405-5406
23. Furka Á, Sebestyén F, Asgedom M, Dibó G (1988) 14th International Congress of Biochemistry, Prague, Czechoslovakia, July 10-15, 5, 47
24. Lam KS, Salmon SE, Hersh EM, Hruby VJ, Kazmierski WM, Knapp RJ (1991) Nature (Lond) 354, 84-86
25. Brenner S, Lerner RA (1992) Proc Natl Acad Sci USA 89, 5381-5383
26. Ohlmeyer MHJ, Swanson RN, Dillard LW et al (1993) Proc Natl Acad Sci USA 90, 10922-10926
27. Geysen HM, Meloen RH, Barteling SJ (1984) Proc Natl Acad Sci USA 81, 3998-4002
28. Gausepohl H, Boulin C, Kraft M, Frank RW (1992) Peptide Res 5, 315-320
29. Wang JX, Bray AM, Di Pasquale AJ, Mayi NJ, Geysen HM (1993) Bioorg Med Chem Lett 3, 447-450
30. Bray AM, Jhingran AG, Valerio RM, Mayi NJ (1994) J Org Chem 59, 2197-2203
31. Bunin BA, Plunkett MJ, Ellman JA (1994) Proc Natl Acad Sci USA 91, 4708-4712
32. Virgilio AA, Ellman JA (1994)J Am Chem Soc 116, 11580-11581
33. Bray AM, Chiefari DS, Valerio RM, Mayi NJ (1995) Tetrahedron Lett 36, 5081-5084
34. Fodor SPA, Read JL, Pirrung MC, Stryer L, Lu AT, Solas D (1991) Science 251, 767
35. Moran EJ, Wilson TE, Cho CY, Cherry SR, Schultz PG (1995) Biopolymers (Peptide Science) 37, 213-219
36. Holmes CP, Adams CL, Kochersperger LM, Mortensen RB, Aldwin LA (1995) Biopolymers (Peptide Science) 37, 199-211