Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel

Journal of Biological Chemistry

Volumn 271, Issue 16, 1996, Pages 9422-9428

  Dias Kadambi, Belinda L ^a   Drum, Chester L ^b   Hanck, Dorothy A ^b,c   Blumenthal, Kenneth M ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c AMERICAN HEART ASSOCIATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHOPLEURINE B; ISOLEUCINE; LEUCINE; MARINE TOXIN; MUTANT PROTEIN; SODIUM CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE TRANSPORT; HEART MUSCLE CELL; HYDROPHOBICITY; ION TRANSPORT; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA PRIMERS; GENES, SYNTHETIC; ISOLEUCINE; KINETICS; LEUCINE; MEMBRANE POTENTIALS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCARDIUM; NEUROBLASTOMA; NEURONS; PEPTIDES; POLYMERASE CHAIN REACTION; RATS; RECOMBINANT PROTEINS; SEA ANEMONES; SODIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TUMOR CELLS, CULTURED; VERATRIDINE;

ANEMONE; ANIMALIA;

EID: 0030010219     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.16.9422     Document Type: Article

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