Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo

British Journal of Pharmacology

Volumn 118, Issue 2, 1996, Pages 369-377

  Mathot R A A ^a,b   Soudijn, W ^a   Breimer, D D ^a   Ijzerman, A P ^a   Danhof, M ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Pharmacy of the Hospitals of the Hague   (Netherlands)

Author keywords

2 chloroadenosine (CADO); Adenosine receptor; Cardiovascular effects; In vivo potency; Intrinsic activity; Pharmacokinetic pharmacodynamic modelling

Indexed keywords

2 CHLOROADENOSINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; CAFFEINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG POTENCY; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; VASCULAR RESISTANCE;

2-CHLOROADENOSINE; ANIMALS; CAFFEINE; HEMODYNAMIC PROCESSES; MALE; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; THEOPHYLLINE;

EID: 0030010050     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15412.x     Document Type: Article

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