Treatment of central precocious puberty: Comparison of urinary gonadotropin excretion and gonadotropin-releasing hormone (GnRH) stimulation tests in monitoring GnRH analog therapy

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 4, 1996, Pages 1353-1356

  Witchel, Selma F ^a   Baens Bailon, Rita G ^a   Lee, Peter A ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; FOLLITROPIN; GONADORELIN; GONADORELIN DERIVATIVE; GONADOTROPIN; LEUPRORELIN; LUTEINIZING HORMONE;

ARTICLE; CHILD; CLINICAL ARTICLE; DRUG MONITORING; FEMALE; FLUOROIMMUNOASSAY; HUMAN; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; INTRAVENOUS DRUG ADMINISTRATION; PRECOCIOUS PUBERTY; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; URINARY EXCRETION;

CHILD; FEMALE; FLUOROIMMUNOASSAY; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HUMANS; LEUPROLIDE; LUTEINIZING HORMONE; PUBERTY, PRECOCIOUS; REAGENT KITS, DIAGNOSTIC;

EID: 0030009628     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.4.1353     Document Type: Article

References (15)

1. Parker KL, Lee PA. 1989 Depot leuprolide acetate treatment for precocious puberty. J Clin Endocrinol Metab. 69:689-691.
2. Kappy M, Stuart T, Perelman A, Clemons R. 1989 Suppression of gonadotropin secretion by a long-acting gonadotropin-releasing hormone analog (leuprolide acetate, Lupron Depot) in children with precocious puberty. J Clin Endocrinol Metab. 69:1087-1089.
3. Manasco PK, Pescovitz OH, Hill SC, et al. 1989 Six-year results of luteinizing hormone releasing hormone (LHRH) agonist treatment in children with LHRH-dependent precocious puberty. J Pediatr. 115:105-108.
4. Lee PA, Page JG, Leuprolide Study Group. 1989 Effects of leuprolide in the treatment of central precocious puberty. J Pediatr. 114:321-324.
5. Parker KL, Baens-Bailon RG, Lee PA. 1991 Depot leuprolide acetate dosage for sexual precocity. J Clin Endocrinol Metab. 71:50-52.
6. Wheeler MD, Styne DM. 1990 Diagnosis and management of precocious puberty. Pediatr Clin North Am. 37:1255-1271.
7. Kulin HE, Bell PM, Santen RJ, Ferber AJ. 1975 Integration of pulsatile gonadotropin secretion by timed urinary measurements: an accurate and sensitive 3-hour test. J Clin Endocrinol Metab. 40:783-789.
8. Chipman JJ, Moore RJ, Marks JF, Fevre TS, Ramsey J, Boyar RM. 1991 Interrelationship of plasma and urinary gonadotropins: correlations for 24 hours, for sleep/wake periods, and for 3 hours after luteinizing hormone-releasing hormone stimulation. J Clin Endocrinol Metab. 52:225-230.
9. Kulin HE, Santer SJ. 1977 Timed urinary gonadotropin measurements in normal infants, children, and adults, and in patients with disorders of sexual maturation. J Pediatr. 90:760-765.
10. Maesaka H, Suwa S, Tachibana K, Kikuchi N. 1990 Quantification of urinary gonadotropins in normal children. Pediatr Res. 28:401-404.
11. Maesaka H, Suwa S, Tachibana K, Kikuchi N. 1990 Monthly urinary LH and FSH secretory patterns in normal children and patients with sexual disorders. Pediatr Res. 28:405-410.
12. Rime JL, Zumsteg U, Blumberg A, Hadziselimovic F, Girard J, Zurbrugg RP. 1988 Long-term treatment of precocious puberty with an intranasal LHRH analogue: control of pituitary function by urinary gonadotropins. Eur J Pediatr. 147:263-269.
13. Wu FC, Butler GE, Kelnar CJ, Stirling HF, Huhtaniemi I. 1991 Patterns of pulsatile luteinizing hormone and follicle-stimulating hormone secretion in prepubertal (midchildhood) boys and girls and patients with idiopathic hypogonadotropic hypogonadism (Kallmann's syndrome): a study using an ultra-sensitive time-resolved immunofluorometric assay. J Clin Endocrinol Metab. 72:1229-1237.
14. Demir A, Alfthan H, Stenman U-H, Voutilainen R. 1994 A clinically useful method for detecting gonadotropins in children: assessment of luteinizing hormone and follicle-stimulating hormone from urine as an alternative to serum by ultrasensitive time-resolved immunofluorometric assays. Pediatr Res. 36:221-226.
15. Demir A, Dunkel L, Stenman U-H, Voutilaninen R. 1995 Age-related course of urinary gonadotropins in children. J Clin Endocrinol Metab. 80:1457-1460.