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1
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0028058673
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Symptomatic fracture incidence in elderly men and women: The Dubbo Osteoporosis Epidemiology Study
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Jones G, Nguyen TV, Sambrook PN, Kelly PJ, Eisman JA: Symptomatic fracture incidence in elderly men and women: The Dubbo Osteoporosis Epidemiology Study. Osteoporos Int 1994, 4:277-282. The incidence of all symptomatic osteoporotic fractures was observed longitudinally in ∼2000 elderly men and women. For subjects older than 60 years, the remaining lifetime risk of symptomatic osteoporotic fracture is >50% for women and >25% for men.
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2
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0027460909
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Prediction of osteoporotic fractures by postural instability and bone density
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Nguyen TV, Sambrook PN, Kelly PJ, Jones G, Lord SR, Freund J, Eisman JA: Prediction of osteoporotic fractures by postural instability and bone density. Br Med J 1993, 307:1111-1115.
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Br Med J
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Nguyen, T.V.1
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Hip fractures in the elderly: A world-wide projection
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Cooper C, Campion G, Melton LJ III: Hip fractures in the elderly: A world-wide projection. Osteoporos Int 1992, 2:285-289.
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Cooper, C.1
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Risk factors for hip fracture in white women
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Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley JC, Black D, Vogt TM: Risk factors for hip fracture in white women. New Engl J Med 1995, 332:767-773. This prospective study examined the risk of hip fracture in ∼10 000 white women aged 65 years or older. Low calcaneal bone density, age, relatively poor health, muscle weakness, poor vision and therapy for thyroid disease, epilepsy and use of long-acting benzodiazepines were all risk factors for subsequent hip fracture. Prior oestrogen use was protective.
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Cummings, S.R.1
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Ensrud, K.E.6
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5
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0028260829
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Bone mineral density and risk factors of osteoporosis - A population based study of 1600 perimenopausal women
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Kroger H, Tuppurainen M, Honkanen R, Alhava E, Saarikoski S: Bone mineral density and risk factors of osteoporosis - a population based study of 1600 perimenopausal women. Calcif Tissue Int 1994, 55:1-7. In this population-based study of 1600 pre-menopausal women, weight, menopausal status, age and grip strength were independent predictors of bone mineral density of spine and hip and physical activity per se was a determinant of bone mineral density at hip. However, these factors taken in combination explain only 20% of bone density variability.
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Kroger, H.1
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6
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0029116697
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Alendronate treatment of the postmenopausal woman: Effect of multiple dosages on bone mass and bone remodelling
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Chesnut CH, McClung MR, Ensrud KE, Bell NH, Genant HK, Harris ST, Singer FR, Stock JL, Yood RA, Delmas PD et al.: Alendronate treatment of the postmenopausal woman: effect of multiple dosages on bone mass and bone remodelling. Amer J Med 1995, 99:144-152.
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Chesnut, C.H.1
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7
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0028851590
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The Alendronate Phase III Osteoporosis Treatment Study Group: Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal women
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Liberman UA, Weiss SR, Broll J, Minne HW, Quan H, Bell NH, Rodriguez-Portales J, Downs RW, DeQueker J, Favus M et al. The Alendronate Phase III Osteoporosis Treatment Study Group: Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal women. New Engl J Med 1995, 333:1437-1443. A new generation bisphosphonate, Alendronate, was compared with calcium alone over three years in 994 women with postmenopausal osteoporosis. The women receiving alendronate increased bone density at all sites relative to control by up to 8.8%. Moreover, the number and progression of vertebral deformities and the number of peripheral fractures were all significantly fewer in treated women.
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Liberman, U.A.1
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8
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0027965382
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Progressive femoral neck bone loss: Longitudinal findings from the Dubbo Osteoporosis Epidemiology Study
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Jones G, Nguyen TV, Sambrook PN, Kelly PJ, Eisman JA: Progressive femoral neck bone loss: longitudinal findings from the Dubbo Osteoporosis Epidemiology Study. Br Med J 1994, 309:691-695. This prospective longitudinal study of bone density in elderly men and women showed progressive bone loss at the femoral neck with no suggestion of slowing bone loss with advancing age.
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Br Med J
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Jones, G.1
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9
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Bone mass is low in relatives of osteoporotic patients
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Evans RA, Marel GM, Lancaster EK, Kos S, Evana M, Wong SYP: Bone mass is low in relatives of osteoporotic patients. Ann Intern Med 1988, 109:870-873.
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10
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Reduced femoral neck bone density in the daughters of women with hip fractures: The role of low bone density in the pathogenesis of osteoporosis
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Seeman E, Tsalamandris C, Formica C, Hopper JL, McKay J: Reduced femoral neck bone density in the daughters of women with hip fractures: the role of low bone density in the pathogenesis of osteoporosis. J Bone Min Res 1994, 9:739-743. 41 daughters of 74 women with hip fractures had proximal femur bone density lower than expected for their age, although not as low as in their mothers. Their age-adjusted values were not low in the lumbar spine.
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J Bone Min Res
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Seeman, E.1
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11
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0028201047
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Family history of osteoporosis and bone mineral density at the axial skeleton: The Rancho Bernardo study
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Soroko SB, Barrett-Connor E, Edelstein SL, Kritz-Siverstein D: Family history of osteoporosis and bone mineral density at the axial skeleton: the Rancho Bernardo study. J Bone Miner Res 1994, 9:761-769. A family history of osteoporosis identified those with lower bone density, amongst almost 1500 elderly white men and women, even after adjustment for age, oestrogen use and other external factors. Both maternal and paternal history contributed to disease onset.
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J Bone Miner Res
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Soroko, S.B.1
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12
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Familial comparison of bone mineral density at the proximal femur and lumbar spine
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McKay HA, Bailey DA, Wilkinson AA, Houston CS: Familial comparison of bone mineral density at the proximal femur and lumbar spine. Bone Miner 1994, 24:95-110. This study of mother/daughter (41), mother/son (42), mother/grandmother (24) and mother/grandmother/daughter (18) sets showed correlations (0.4-0.6) in age-adjusted values for bone density at the proximal femur and lumbar spine.
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Bone Miner
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McKay, H.A.1
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Kelly PJ, Hopper JL, Macaskill GT, Pocock NA, Sambrook PN, Eisman JA: Genetic factors in bone turnover. J Clin Endocrinol Metab 1991, 72:808-813.
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Kelly, P.J.1
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14
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Genetic determination of changes in bone density with age: A twin study
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Kelly PJ, Nguyen T, Pocock N, Hopper J, Sambrook PN, Eisman JA: Genetic determination of changes in bone density with age: a twin study. J Bone Miner Res 1993, 8:11-17.
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J Bone Miner Res
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Kelly, P.J.1
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15
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Genetic determinants of bone mass in adult woman; a re-evaluation of the model and the potential importance of gene interaction on heritability estimates
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Slemenda CW, Christian JC, Williams CJ, Norton JA, Johnston CC Jr: Genetic determinants of bone mass in adult woman; a re-evaluation of the model and the potential importance of gene interaction on heritability estimates. J Bone Miner Res 1991, 6:561-567
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Slemenda, C.W.1
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Johnston C.C., Jr.5
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16
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0028333925
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Genetic determinants of type I collagen synthesis and degradation: Further evidence for genetic regulation of bone turnover
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Tokita A, Kelly PJ, Nguyen TV, Qi J-C, Morrison NA, Risteli L, Risteli J, Sambrook PN, Eisman JA: Genetic determinants of type I collagen synthesis and degradation: further evidence for genetic regulation of bone turnover. J Clin Endocrinol Metab 1994, 78:1461-1466. In 164 healthy female twins, genetic effects were apparent in markers of type I, but not type III, collagen synthesis and degradation. Higher bone turnover, as measured by formation markers, was associated with lower bone density.
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J Clin Endocrinol Metab
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Tokita, A.1
Kelly, P.J.2
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Morrison, N.A.5
Risteli, L.6
Risteli, J.7
Sambrook, P.N.8
Eisman, J.A.9
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Peak bone mass in young women
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Teegarden D, Proulx WR, Martin BR, Zhao J, McCabe GP, Lyle RM, Peacock M, Slemenda C, Johnston CC, Weaver CM: Peak bone mass in young women. J Bone Miner Res 1995, 10:711-715. In this study of 247 young healthy girls and young women, age, weight and height were major factors in predicting total body bone density and bone mineral content.
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J Bone Miner Res
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Teegarden, D.1
Proulx, W.R.2
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Lyle, R.M.6
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Johnston, C.C.9
Weaver, C.M.10
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18
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0028965490
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Determinants of bone mass in 10- To 26-year old females: A twin Study
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Young D, Hopper JL, Nowson CA, Green RM, Sherwin AJ, Kaymacki B, Smid M, Guest CS, Larkins RG, Wark JD: Determinants of bone mass in 10- to 26-year old females: a twin Study. J Bone Miner Res 1995, 10:558-567. This study of 430 female twins, aged between 10-26 years, showed that many potential effectors of bone density - including statural factors - were often collinear within pairs. However, menarchial status, height and lean mass were independent predictors of bone mass in these young women.
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J Bone Miner Res
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Young, D.1
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Guest, C.S.8
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19
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Risk factors for falls as a cause of hip fracture in women
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Grisso JA, Kelsey JL, Strom BL, Chiu GY, Maislin G, O'Brien LA, Hoffman S, Kapkin F: Risk factors for falls as a cause of hip fracture in women. N Engl J Med 1991, 324:1326-1331.
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20
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Risk factors for hip fracture in black women
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Grisso JA, Kelsey JL, Strom BL, O'Brien LA, Maislin G, La Pann, Samelson L, Hoffman S and the Northeast Hip Fracture Study Group: Risk factors for hip fracture in black women. N Engl J Med 1994, 330:1555-1559. In this case controlled study of 114 black women with a hip fracture, postmenopausal oestrogen therapy for 1 year or more was protective against hip fracture as was high body mass index. Prior stroke, use of a walking aid and heavy alcohol consumption increased risk.
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N Engl J Med
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Grisso, J.A.1
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Samelson, L.7
Hoffman, S.8
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21
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0028239272
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Mutation analysis of coding sequences for type I procollagen in individuals with low bone density
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2 (I) chains are listed.
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J Bone Miner Res
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Spotila, L.D.1
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22
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0026000415
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Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: Evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta
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Spotila LD, Constantinou CD, Sereda L, Ganguly A, Riggs BL, Prockop DJ: Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta. Proc Natl Acad Sci USA 1991, 88:5423-5427.
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Osteoporotic fracture and reduced bone density related to a polymorphism in the transcriptional control region of the collagen type I α 1 gene
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Grant SFA, Reid DM, Ralston SH: Osteoporotic fracture and reduced bone density related to a polymorphism in the transcriptional control region of the collagen type I α 1 gene. J Bone Miner Res 1995, 10(Suppl 1):S165.
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Estrogen resistance caused by a mutation in the estrogenreceptor gene in a man
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Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB, Korach KS: Estrogen resistance caused by a mutation in the estrogenreceptor gene in a man. N Engl J Med 1994, 331:1088-1089. This report describes a young man with oestrogen resistance due to a mutation in the oestrogen receptor gene. He was tall with unfused epiphyses and, of considerable interest, had very low bone density.
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N Engl J Med
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Smith, E.P.1
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25
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Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis
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Sano M, Inoue S, Hosoi T, Ouchi Y, Emi M, Shiraki M, Orimo H: Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis. Biochem Biophys Res Commun 1995, 217:378-383. A dinucleotide repeat polymorphism was identified in 144 healthy postmenopausal Japanese women. An uncommon allele, present in ∼10% of the group, was associated with lower bone density (0.6 to 1.1 SD unit) than in those without that allele.
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Biochem Biophys Res Commun
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Sano, M.1
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Estrogen receptor genotypes and bone mineral density in women and men
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Qi JC, Morrison NA, Nguyen TV, White CP, Kelly PJ, Sambrook PN, Eisman JA: Estrogen receptor genotypes and bone mineral density in women and men. J Bone Miner Res 1996, 10(Suppl 1):S170. This study suggested relationships between oestrogen receptor genotype and bone mineral density in both men and women.
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J Bone Miner Res
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Qi, J.C.1
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Contribution of trans-acting factor alleles to normal physiological variability: Vitamin D receptor gene polymorphisms and circulating osteocalcin
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Morrison NA, Yeoman R, Kelly PJ, Eisman JA: Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphisms and circulating osteocalcin. Proc Natl Acad Sci USA 1992, 89: 6665-6669.
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Prediction of bone density by vitamin D receptor alleles
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Morrison NA, Qi JC, Tokìta A, Kelly PJ, Croft L, Nguyen TV, Sambrook PN, Eisman JA: Prediction of bone density by vitamin D receptor alleles. Nature 1994, 367:284-287. Common polymorphic alleles in the VDR gene were associated with bone density differences (∼1.0 SD unit) in these twin and other unrelated Australian subjects. Primers are listed.
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Nature
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Morrison, N.A.1
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Hustmyer FG, Peacock M, Hui S, Johnston CC, Christian JC: Bone mineral density in relation to polymorphisms at the vitamin D receptor locus. J Clin Invest 1994, 94:2130-2134. Polymorphisms at the VDR locus were not found to be associated with bone density in either twin or non-twin populations.
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J Clin Invest
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Hustmyer, F.G.1
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Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women
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Garnero P, Borel O, Sornayrendu, Delmas PD: Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women. J Bone Miner Res 1995, 10:1283-1288. In this study of healthy premenopausal women in Lyon, France, there was no relationship between VDR gene polymorphisms and either markers of bone turnover or bone mass.
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J Bone Miner Res
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Vitamin D receptor gene alleles and osteoporosis: An affirmative view
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Eisman JA: Vitamin D receptor gene alleles and osteoporosis: an affirmative view (Editorial). J Bone Miner Res 1995, 10:1289-1293. This editorial reviews the current evidence in relation to both genetics of osteoporosis and possible roles of VDR gene polymorphisms.
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J Bone Miner Res
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Peacock M: Vitamin D receptor gene alleles and osteoporosis: contrasting view (Editorial). J Bone Miner Res 1995, 10:1294-1297. This editorial reviews the current evidence in relation to VDR gene polymorphisms and bone density.
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J Bone Miner Res
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Vitamin D receptor genotypes in osteoporosis
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Melhus H, Kindmark A, Amer S, Wilen B, Lindh E, Ljunghall S: Vitamin D receptor genotypes in osteoporosis. Lancet 1994, 344:949. VDR genotypes were evaluated in a small number of osteoporotic and non-osteoporotic subjects. The allele, which has been associated with lower bone density in other studies, was two-fold more common in the fracture group. This apparent difference, however, was not statistically significant - possibly because of the sample size.
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Lancet
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Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women
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Looney JE, Yoon HK, Fischer M, Farley SM, Farley JR, Wergedal JE, Baylink DJ: Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women. J Clin Endocrinol Metab 1995, 80:2158-2162.
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The impact of common allelic variation at the vitamin D receptor locus on bone mass Is not clinically relevant
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Scholler J, Jorgensen HL, Sand JC, Jensen M, Hassager C, Christiansen C: The impact of common allelic variation at the vitamin D receptor locus on bone mass Is not clinically relevant J Bone Miner Res 1995, 10(Suppl):S161.
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Vitamin D receptor genotypes and bone mineral density
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Kroger H, Mahonen A, Ryhanen S, Turunen AM, Alhava E, Maenpaa P: Vitamin D receptor genotypes and bone mineral density. Lancet 1995, 345:1239.
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Lancet
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Nguyen TV, Kelly PJ, Morrison NA, Sambrook PN, Eisman JA: Vitamin D receptor genotypes in osteoporosis. Lancet 1994, 344:1580-1581. This letter describes power calculations of sample sizes required for studies of VDR genotypes in relation to bone density.
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Nguyen, T.V.1
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Sambrook, P.N.4
Eisman, J.A.5
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38
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0000369931
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Vitamin D receptor genotypes in type1 osteoporosis
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Gallagher JC, Goldgar D, Kinyamu H, Fannon P: Vitamin D receptor genotypes in type1 osteoporosis. J Bone Miner Res 1994, 9(Suppl 1):143.
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(1994)
J Bone Miner Res
, vol.9
, Issue.1 SUPPL.
, pp. 143
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Gallagher, J.C.1
Goldgar, D.2
Kinyamu, H.3
Fannon, P.4
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39
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0028958414
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Vitamin D receptor gene polymorphism and bone loss
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Keen RW, Major PJ, Lanchbury JS, Spector TD: Vitamin D receptor gene polymorphism and bone loss. Lancet 1995, 345:990. In this study of early post-menopausal bone loss, there was no apparent VDR allele effect on rates of loss.
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(1995)
Lancet
, vol.345
, pp. 990
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Keen, R.W.1
Major, P.J.2
Lanchbury, J.S.3
Spector, T.D.4
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40
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0028998941
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Vitamin D receptor gene (VDR) alleles and bone density in post menopausal women; a UK twin study
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Spector TD, Keen RW, Arden NK, Major PJ, Baker JR, Morrison NA, Nguyen TV, Kelly PJ, Sambrook PN, Lanchbury JS, Eisman JA: Vitamin D receptor gene (VDR) alleles and bone density in post menopausal women; a UK twin study. BMJ 1995, 310:1357-1360. In this study of VDR alleles and bone density in post-menopausal twins in the UK, a gene effect was apparent at the femoral neck as well as other sites.
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(1995)
BMJ
, vol.310
, pp. 1357-1360
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Spector, T.D.1
Keen, R.W.2
Arden, N.K.3
Major, P.J.4
Baker, J.R.5
Morrison, N.A.6
Nguyen, T.V.7
Kelly, P.J.8
Sambrook, P.N.9
Lanchbury, J.S.10
Eisman, J.A.11
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41
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0029068205
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Contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women
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Riggs BL, Nguyen TV, Melton LJ III, Morrison NA, O'Fallon WM, Kelly PJ, Egan KS, Sambrook PN, Muhs JM, Eisman JA: Contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res 1995, 10:991-996. In this study of 182 normal and osteoporotic women, VDR alleles were associated with bone density. However, the genotype effect was not seen in women older than 70 years, suggesting an overriding environmental effect.
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(1995)
J Bone Miner Res
, vol.10
, pp. 991-996
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Riggs, B.L.1
Nguyen, T.V.2
Melton L.J. III3
Morrison, N.A.4
O'Fallon, W.M.5
Kelly, P.J.6
Egan, K.S.7
Sambrook, P.N.8
Muhs, J.M.9
Eisman, J.A.10
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42
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0029144545
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Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density
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Barger-Lux MJ, Heaney RP, Hayes J, DeLuca HF, Johnson ML, Gong G: Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density. Calcif Tissue Int 1995, 57:161-162. In 32 healthy premenopausal women, bone mineral content, but not duodenal mucosa VDR density, were related to VDR alleles. Part of this relationship related to body weight, suggesting an effect on non-calcium nutritional mechanisms and body size.
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(1995)
Calcif Tissue Int
, vol.57
, pp. 161-162
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Barger-Lux, M.J.1
Heaney, R.P.2
Hayes, J.3
DeLuca, H.F.4
Johnson, M.L.5
Gong, G.6
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43
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0029010691
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The Bsml vitamin D receptor restriction length polymorphism (BB) predicts low bone density in premenopausal black and white women
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Fleet JC, Harris SS, Wood RJ, Dawson-Hughes B: The Bsml vitamin D receptor restriction length polymorphism (BB) predicts low bone density in premenopausal black and white women. J Bone Miner Res 1995, 10:985-990. This study of 155 black and while women aged between 20-40 years showed a 6-8% difference in bone density according to VDR genotype.
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(1995)
J Bone Miner Res
, vol.10
, pp. 985-990
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Fleet, J.C.1
Harris, S.S.2
Wood, R.J.3
Dawson-Hughes, B.4
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44
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0030069441
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The association between vitamin receptor gene polymorphisms and bone mineral density at the spine, hip and total body in premenopausal women
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Salamone LM, Ferell R, Black DM, Palermo L, Epstein RS, Petro N, Steadman N, Kuller LH, Cauley JA: The association between vitamin receptor gene polymorphisms and bone mineral density at the spine, hip and total body in premenopausal women. Osteoporos Int 1996, 6:63-68. This large study of 470 premenopausal white women, aged 44-50 years, found a VDR gene effect on bone density at the spine and hip sites of up to 2.9% or 0.3 SD units. There was a small but not significant effect (0.4%) on total body bone density.
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(1996)
Osteoporos Int
, vol.6
, pp. 63-68
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Salamone, L.M.1
Ferell, R.2
Black, D.M.3
Palermo, L.4
Epstein, R.S.5
Petro, N.6
Steadman, N.7
Kuller, L.H.8
Cauley, J.A.9
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45
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0027968575
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Vitamin D receptor gene polymorphism and bone mineral density in healthy Japanese women
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Yamagata Z, Miyamura T, Lijima S, Asaka A, Sasaki M, Kato J, Koizumi K: Vitamin D receptor gene polymorphism and bone mineral density in healthy Japanese women. Lancet 1994, 344:1027. This study confirmed an association between VDR gene polymorphisms and bone density in healthy Japanese women.
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(1994)
Lancet
, vol.344
, pp. 1027
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Yamagata, Z.1
Miyamura, T.2
Lijima, S.3
Asaka, A.4
Sasaki, M.5
Kato, J.6
Koizumi, K.7
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46
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0029056620
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VDR gene polymorphisms and vitamin D analog treatment in Japanese
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Matsuyama T, Ishii S, Tokita A, Yabuta K, Yamamori S, Morrison NA, Eisman JA: VDR gene polymorphisms and vitamin D analog treatment in Japanese. Lancet 1995, 345:1238-1239. This study reported VDR genotype-related differences in the response of bone density to active vitamin D analogues in osteoporotic Japanese women.
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(1995)
Lancet
, vol.345
, pp. 1238-1239
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Matsuyama, T.1
Ishii, S.2
Tokita, A.3
Yabuta, K.4
Yamamori, S.5
Morrison, N.A.6
Eisman, J.A.7
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47
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0343496898
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Haplotypes at the vitamin D receptor gene locus are associated with bone mineral density
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in press
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Uitterlinden AG, Pols HAP, Burger H, Van Daele PLA, Van Duijn CM, Hofman A, Birkenhager JC, Van Leeuwen JPTM: Haplotypes at the vitamin D receptor gene locus are associated with bone mineral density. J Bone Miner Res 1996, in press. This large scale study of elderly men and women in Rotterdam established an association between VDR gene haplotypes and bone mineral density. The size of effect was comparable to that seen in other positive studies, but intrigingly appears to be in the opposite sense.
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(1996)
J Bone Miner Res
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Uitterlinden, A.G.1
Pols, H.A.P.2
Burger, H.3
Van Daele, P.L.A.4
Van Duijn, C.M.5
Hofman, A.6
Birkenhager, J.C.7
Van Leeuwen, J.P.T.M.8
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49
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0028841890
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Vitamin D receptor genotypes in primary hyperparathtyoidism
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Carling T, Kindmark A, Hellman P, Lundgren E, Ljunghall S, Rastad J, Akerstrom G, Melhus H: Vitamin D receptor genotypes in primary hyperparathtyoidism. Nat Med 1995, 1:1309-1311.
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(1995)
Nat Med
, vol.1
, pp. 1309-1311
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Carling, T.1
Kindmark, A.2
Hellman, P.3
Lundgren, E.4
Ljunghall, S.5
Rastad, J.6
Akerstrom, G.7
Melhus, H.8
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50
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0028967366
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Vitamin D receptor gene polymorphisms and the rate of change of lumbar spine bone mineral density in elderly men and women
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Ferrari S, Rizzoli R, Chevalley T, Slosman D, Eisman JA, Bonjour J-P: Vitamin D receptor gene polymorphisms and the rate of change of lumbar spine bone mineral density in elderly men and women. Lancet 1995, 345:423-424. This study reports differences in response to calcium supplementation in lumbar spine density in elderly men and women according to VDR gene genotype.
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(1995)
Lancet
, vol.345
, pp. 423-424
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Ferrari, S.1
Rizzoli, R.2
Chevalley, T.3
Slosman, D.4
Eisman, J.A.5
Bonjour, J.-P.6
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51
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0029046170
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Vitamin D receptor alleles and rates of bone loss: Influences of years since menopause and calcium intake
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Krall EA, Parry P, Lichter JB, Dawson-Hughes B: Vitamin D receptor alleles and rates of bone loss: influences of years since menopause and calcium intake. J Bone Miner Res 1995, 10:978-984. This study in 229 healthy post-menopausal women, previously studied as part of a calcium intervention study, showed differences in response of bone density to calcium supplementation according to VDR genotype.
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(1995)
J Bone Miner Res
, vol.10
, pp. 978-984
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Krall, E.A.1
Parry, P.2
Lichter, J.B.3
Dawson-Hughes, B.4
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52
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0028572389
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Genetics of Osteoporosis
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Sambrook PN, Kelly PJ, Morrison N, Eisman J: Genetics of Osteoporosis. Brit J Rheumatol 1994, 33:1007-1011. A review of the current studies of the genetics of osteoporosis.
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(1994)
Brit J Rheumatol
, vol.33
, pp. 1007-1011
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Sambrook, P.N.1
Kelly, P.J.2
Morrison, N.3
Eisman, J.4
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53
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0028099889
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Vitamin D receptor alleles and bone physiology
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White CP, Morrison N, Gardiner E, Eisman JA: Vitamin D receptor alleles and bone physiology. J Cell Biochem 1994, 56:307-314. A review of studies of VDR alleles in relation to bone and calcium homoeostasis and changes in calcium physiology.
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(1994)
J Cell Biochem
, vol.56
, pp. 307-314
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White, C.P.1
Morrison, N.2
Gardiner, E.3
Eisman, J.A.4
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