Combined locoregional and systemic adjuvant chemotherapy of stage II and III rectal carcinoma

Oncology Research and Treatment

Volumn 19, Issue 2, 1996, Pages 147-151

  Kornek, G V ^a   Depisch, D ^b   Salem, G ^c   Karall, M ^b   Rohrbacher, M ^c   Scheithauer, W ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Allgemeines Krankenhaus Wr Neustadt   (Germany)

^c GENERAL HOSPITAL KLAGENFURT   (Austria)

Author keywords

5 Fluorouracil; Adjuvant chemotherapy; Leucovorin; Locoregional Chemotherapy; Mitoxantrone; Rectal cancer

Indexed keywords

FLUOROURACIL; FOLINIC ACID; MITOXANTRONE;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; RECTUM CARCINOMA;

EID: 0030008784     PISSN: 22965270     EISSN: None     Source Type: Journal    
DOI: 10.1159/000218781     Document Type: Article

References (17)

1. Silverberg E, Lubcra JA: Cancer statistics. Cancer 1989:39:1-23.
2. Minsky BD, Mies C, Recht A, Rich TA. Chaffey JT: Resectable adenocarcinoma of the rectosigmoid and rectum I: Patterns of failure and survial. Cancer 1988:61:1408-1416.
3. Rich T, Gunderson LL. Lew R, Galdibini JJ, Cohen AM, Donaldson G: Patterns of recurrence of rectal cancer after potentially curative surgery. Cancer 1983:52:1317-1329.
4. Fisher B, Wolmark N, Rockette H, Redmond C, Deutsch M, Wickerham DL, Fischer ER, Caplan R, Jones J, Lerner H, Gordon P, Feldmann M, Cruz A and other NSABP investigators: Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP protocol R-01. J Natl Cancer Inst 1988:80:21-29.
5. Izar F, Fourtanicr G, Pradcre B, Chiotasso P, Bloom E, Fontes-Dislaire I, Bugat R, Daly N: Preoperative radiotherapy as adjuvant treatment in rectal cancer. World J Surg 1992:16:106-112.
6. O’Connell MJ, Gunderson LL, Fleming TR: Surgical adjuvant therapy of rectal cancer. Semin Oncol 1988:15:138-145.
7. NIH consensus conference on adjuvant therapy for patients with colon and rectal cancer. JAMA 1990: 264:1444-1450.
8. National Cancer Institute: Adjuvant therapy of rectal cancer. Clinical Announcement on March 14. 1991.
9. Krook JE, Moertel CG, Gunderson LL, Wieand HS, Collins RT, Beart RW: Effective surgical adjuvant therapy for high risk rectal carcinoma. N Engl J Med 1991:324:709-715.
10. Los G, McVie JG: Experimental and clinical status of intraperitoneal chemotherapy. Eur J Cancer 1990:26:755-762.
11. Stewart DJ, Green RM, Mikhael NZ, Montpetit V, Thibault M, Maroun JA: Human autopsy tissue concentrations of mitoxantrone. Cancer Treat Rep 1987:70:1255-1261.
12. Schcithauer W, Tremsch EM, Petzl DH, Jakesz R: Application of a new radiometric system for identification of potentially useful drug combinations for treatment of human gastrointestinal adenocarcinoma. Oncology 1989;46:143-149.
13. The Advanced Colorectal Cancer Meta-Analysis Project: Modulation of fluorouracil by leucovorin patients with advanced colorectal cancer: Evidence in terms of response rate. J Clin Oncol 1992;10: 896-903.
14. Miller AB, Hoogstraten B, Staquet M: Reporting results oi cancer treatment. Cancer 1981:47:207-214.
15. Kaplar, LK, Meier P: Nonparametric estimation from incomplete observations. Am J Stat Assoc 1958:53: 457-481.
16. Mantel H, Hacnszel W: Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959:22:719-748.
17. O’Connell MJ, Martcnson JA, Wieand HS, Krook JE, Macdonald JS, Haller DG, Mayer RJ, Gunderson LL, Rich TA: Improving adjuvant therapy for rectal cancer by combining protractcd-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994:331:502-507.