Increased sister chromatid exchange (SCE) frequencies in lymphocytes from traffic policemen exposed to automobile exhaust pollution

Human & Experimental Toxicology

Volumn 15, Issue 4, 1996, Pages 301-304

  Chandrasekaran, R ^a   Samy, P L P ^a   Murthy, P B K ^b  

^a BHARATHIAR UNIVERSITY   (India)

^b Fredrick Institute of Plant Protection and Toxicology India   (India)

Author keywords

occupa tional exposure; sister chromatid exchange; traffic policemen; vehicle exhaust

Indexed keywords

POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; AIR POLLUTION; ARTICLE; CONTROLLED STUDY; EXHAUST GAS; HUMAN; HUMAN EXPERIMENT; INDIA; MALE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE; POLICE; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE; WORK SCHEDULE;

ADULT; AIR POLLUTANTS; HUMANS; INDIA; LYMPHOCYTES; MALE; MIDDLE AGED; POLICE; SISTER CHROMATID EXCHANGE; VEHICLE EMISSIONS;

EID: 0030008294     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/096032719601500405     Document Type: Article

References (20)

1. Higginson J., Jenson OM Air pollution and cancer in man. Mohr U, Schmahl D & Tomingas L (eds), IARC, Lyon. 1977.
2. ICRP Task group on lung dynamics committee II. Health Phys 1966; 12: 173.
3. Wark K., Warner F. Air pollution - its origin and control IEPA, New York: Don Domaleng pub. 1976; 418.
4. Tong C., Ved Brat S, Williams GM. SCE induction by polycyclic hydrocarbons in an intact cell system of adult rat liver epithelial cells. Mutation Res 1981; 91: 467-473.
5. De Ratt WK Genotoxicity of aerosol extracts. Some methodological aspects and the contribution of urban and industrial locations. Mutation Res 1983; 116: 57-63.
6. Hadnagy W., Seemayer NH, Tomingas R. Cytogenetic effect of particulate matter in human lymphocyte in vitro. Mutation Res 1986; 175: 97-101.
7. Hadnagy W., Seemayer NH, Tomingas R., Invanfy K. Comparative study of sister chromatid exchanges and chromosomal studies induced by airborne particulates from an urban and highly industrialised location in human lymphocyte culture. Mutation Res 1989; 225: 27-32.
8. Mohankumar R., Chandrasekar R., Rani Mvu. Chromosomal aberrations and sister chromatid exchange frequencies in workers occupationally exposed to textile dyes. Human & Expt Toxicol 1992; 11: 275-277.
9. Perry P., Wolff S. New giemsa method for differential staining of sister chromatids. Nature 258: 121-125.
10. Pitts JN et al. Mutagen in diesel exhaust particulates. Identification and direct activities of 6 nitrobenzo(a)pyrene, I-nitroanthracene, I-nitropyrene and 5-H-phenantro (4,5-bed) pyran-5-one. Mutation Res 1982; 103: 241-249.
11. Tokiwa H., Morita K., Takeyoshi H., Onishi Y. Detection of mutagenic activity in particulate air pollutants. Mutation Res 1977; 48: 237-248.
12. Onishi et al. Detection of mutagenic activity in automobile exhaust. Mutation Res 1980; 77: 229-240.
13. Salmone SF, Heddle JA, Katz M. Mutagenic activity of 30 polycyclic aromatic hydrocarbons (PAH) and oxides in urban airborne particulates. Environ Int 1979; 2: 37-43.
14. Alfeim I. Contribution from motor vehicle exhaust to the mutagenic activity of airborne particles. In Sorso M & Vaino H (eds) Mutagen in our environment New York: Liss. 1982; 235-248.
15. Kaden DA, Hites RA, Thilly WG Mutagenicity of soot and associated polycyclic aromatic hydrocarbons to salmonella typhimurium. Cancer Res 1973; 39: 4152-4159.
16. Wood AW Biological activity of benzo(a)pyrene. An assessment based on mutagenic activities and profiles of polycyclic hydrocarbons and its derivatives. J Biol Chem 1979; 254: 4407-4415.
17. Nordenson I., Nordenson S., Sweins A., Beckman L. Chromosomal aberrations in lead exposed workers. Hereditas 1982; 96: 265-268.
18. Periera MA et al. Effect of diesel exhaust emission particulate and SCE in transplacentally exposed fetal hamster liver. Env Mutagenesis 1982; 4: 215-220.
19. Clark CR et al. Influence of ethanol and methonal gasoline blends on the mutagenicity of particulate exhaust extracts. Arch Env Contam Toxicol 1983; 12: 311-317.
20. Balakrishnamurthy P. Frequency of sister chromatid exchanges in cigarette smokers. Human Genetics 1979; 343-345.