-
1
-
-
0028003745
-
Multiple drug effect analysis with confidence intervals
-
Belen'kii, M. S., and R. F. Schinazi. 1994. Multiple drug effect analysis with confidence intervals. Antiviral Res. 25:1-11.
-
(1994)
Antiviral Res.
, vol.25
, pp. 1-11
-
-
Belen'kii, M.S.1
Schinazi, R.F.2
-
2
-
-
0028224640
-
The effect of 2′,3′ didehydro-3′dcoxythymidinc (D4T) in an in vitro hollow fiber pharmacodynamic model system correlates with results of dose ranging clinical studies
-
Bilello, J. A., G. Bauer, M. N. Dudley, G. A. Cole, and G. L. Drusano. 1994. The effect of 2′,3′ didehydro-3′dcoxythymidinc (D4T) in an in vitro hollow fiber pharmacodynamic model system correlates with results of dose ranging clinical studies. Antimicrob. Agents Chcmother. 38:1386-1391.
-
(1994)
Antimicrob. Agents Chcmother.
, vol.38
, pp. 1386-1391
-
-
Bilello, J.A.1
Bauer, G.2
Dudley, M.N.3
Cole, G.A.4
Drusano, G.L.5
-
3
-
-
0028844440
-
Efficacy of constant infusion A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro
-
Bilello, J. A., P. A. Bilello, J. J. Kort, M. N. Dudley, J. Leonard, and G. L. Drusano. 1995. Efficacy of constant infusion A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro Antimicrob. Agents Chemother. 39:2523-2527.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 2523-2527
-
-
Bilello, J.A.1
Bilello, P.A.2
Kort, J.J.3
Dudley, M.N.4
Leonard, J.5
Drusano, G.L.6
-
5
-
-
85084622795
-
Human serum α1-acid glycoprotein reduces the uptake, intracellular concentration, and antiviral activity of A 80987, an inhibitor of the human immunodeficiency virus type 1 protease
-
in press
-
Bilello, J. A., P. A. Bilello, K. Stellrecht, J. Leonard, D. W. Norbeck, D. J. Kempf, T. Robins, and G. L. Drusano. Human serum α1-acid glycoprotein reduces the uptake, intracellular concentration, and antiviral activity of A 80987, an inhibitor of the human immunodeficiency virus type 1 protease Antimicrob. Agents Chemother., in press.
-
Antimicrob. Agents Chemother.
-
-
Bilello, J.A.1
Bilello, P.A.2
Stellrecht, K.3
Leonard, J.4
Norbeck, D.W.5
Kempf, D.J.6
Robins, T.7
Drusano, G.L.8
-
6
-
-
15844407747
-
Comparison of theoretical and empirical mathematical models of the biochemical effects of combinations of anticancer agents
-
Bravo, G., R. C. Jackson, D. A. Plurad, and W. R. Greco. 1992. Comparison of theoretical and empirical mathematical models of the biochemical effects of combinations of anticancer agents. Proc. Am. Assoc Cancer Res 33:439
-
(1992)
Proc. Am. Assoc Cancer Res
, vol.33
, pp. 439
-
-
Bravo, G.1
Jackson, R.C.2
Plurad, D.A.3
Greco, W.R.4
-
7
-
-
0002658306
-
The median effect principle and the combination index for quantitation of synergism and antagonism
-
T.-C. Chou and D. Rideout (ed.), Academic Press. Inc., San Diego, Calif.
-
Chou, T.-C. 1991. The median effect principle and the combination index for quantitation of synergism and antagonism, p. 61-98. In T.-C. Chou and D. Rideout (ed.), Synergism and antagonism in chemotherapy. Academic Press. Inc., San Diego, Calif.
-
(1991)
Synergism and Antagonism in Chemotherapy
, pp. 61-98
-
-
Chou, T.-C.1
-
8
-
-
0029030227
-
Qualitative study of drug resistance in retroviral protease using structural modeling and site-directed mutagenesis
-
Culberson, J. C., B. L. Bush, and V. V. Sardana, 1994. Qualitative study of drug resistance in retroviral protease using structural modeling and site-directed mutagenesis Methods Enzymol. 241:385-394.
-
(1994)
Methods Enzymol.
, vol.241
, pp. 385-394
-
-
Culberson, J.C.1
Bush, B.L.2
Sardana, V.V.3
-
9
-
-
0004062826
-
ADAPT II: A program package for simulation, identification and optimal experimental design
-
University of Southern California, Los Angeles
-
D'Argenio, D. Z., and A. Schumitzky. 1990. ADAPT II: a program package for simulation, identification and optimal experimental design. User's manual Biomedical Simulations Resource, University of Southern California, Los Angeles.
-
(1990)
User's Manual Biomedical Simulations Resource
-
-
D'Argenio, D.Z.1
Schumitzky, A.2
-
10
-
-
0026579208
-
The HIV-1 protease as a therapeutic target for AIDS
-
Debouck, C. 1992. The HIV-1 protease as a therapeutic target for AIDS. AIDS Res. Hum Rctroviruses 8:153-164.
-
(1992)
AIDS Res. Hum Rctroviruses
, vol.8
, pp. 153-164
-
-
Debouck, C.1
-
11
-
-
0022996630
-
Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5́-triphosphate with human immunodeficiency virus reverse transcriptase
-
Furman, P. A., J. A. Fyfe, M. H. St. Clair, K. Weinhold, et al. 1986. Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5́-triphosphate with human immunodeficiency virus reverse transcriptase Proc. Natl. Acad. Sci. USA 83:8333-8337.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 8333-8337
-
-
Furman, P.A.1
Fyfe, J.A.2
St. Clair, M.H.3
Weinhold, K.4
-
12
-
-
0025045719
-
Population pharmacokinetics of zidovudine
-
Gitterman, S. R., G. L. Drusano, M. J. Egorin, H. C. Standiford, and the VA Cooperative Studies Group. 1990. Population pharmacokinetics of zidovudine. Clin. Pharmacol. Ther. 48:161-167.
-
(1990)
Clin. Pharmacol. Ther.
, vol.48
, pp. 161-167
-
-
Gitterman, S.R.1
Drusano, G.L.2
Egorin, M.J.3
Standiford, H.C.4
-
13
-
-
0026763251
-
In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations
-
Kageyama, S., J. N. Weinstein, T. Shirasaka, D. J. Kempf, D. W. Norbeck, J. J. Plattner, J. Erickson, and H. Mitsuya. 1992. In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations. Antimicrob Agents Chemother 36:926-933.
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 926-933
-
-
Kageyama, S.1
Weinstein, J.N.2
Shirasaka, T.3
Kempf, D.J.4
Norbeck, D.W.5
Plattner, J.J.6
Erickson, J.7
Mitsuya, H.8
-
14
-
-
0026688838
-
Interferon-alpha. zidovudine, and granulocyte-macrophage colony stimulating factor: A phase I AIDS Clinical Trials Group study in patients with Kaposi's sarcoma associated with AIDS
-
Krown, S. E., J. Paredes, D. Bundow, B. Polsky, J. W. Gold, and N. Flomenberg. 1992. Interferon-alpha. zidovudine, and granulocyte-macrophage colony stimulating factor: a phase I AIDS Clinical Trials Group study in patients with Kaposi's sarcoma associated with AIDS. J. Clin. Oncol. 10:1344-1351.
-
(1992)
J. Clin. Oncol.
, vol.10
, pp. 1344-1351
-
-
Krown, S.E.1
Paredes, J.2
Bundow, D.3
Polsky, B.4
Gold, J.W.5
Flomenberg, N.6
-
15
-
-
0028089170
-
Dideoxynucieoside resistance emerges with prolonged zidovudinc monotherapy
-
Mayers, D. L., A. J. Japour, J.-M. Arduino, S. M. Hammer, R. Reichman, K. F. Wagner, R. Chung, J. Lane, C. S. Crumpacker, G. X. McLeod, L. A. Beckett, C. R. Roberts, D. Winslow, D. Burke, and the RV43 Study Group. 1994. Dideoxynucieoside resistance emerges with prolonged zidovudinc monotherapy Antimicrob Agents Chemother. 38:307-314.
-
(1994)
Antimicrob Agents Chemother.
, vol.38
, pp. 307-314
-
-
Mayers, D.L.1
Japour, A.J.2
Arduino, J.-M.3
Hammer, S.M.4
Reichman, R.5
Wagner, K.F.6
Chung, R.7
Lane, J.8
Crumpacker, C.S.9
McLeod, G.X.10
Beckett, L.A.11
Roberts, C.R.12
Winslow, D.13
Burke, D.14
-
16
-
-
0027416573
-
Strategic design and three-dimensional analysis of antiviral drug combinations
-
Prichard, M. N., L. E. Prichard, and C. Shipman, Jr. 1993. Strategic design and three-dimensional analysis of antiviral drug combinations. Antimicrob. Agents Chemother. 37:540-545.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 540-545
-
-
Prichard, M.N.1
Prichard, L.E.2
Shipman Jr., C.3
-
17
-
-
0029039283
-
2 symmetry-based human immunodeficiency virus protease inhibitor
-
2 symmetry-based human immunodeficiency virus protease inhibitor Antimicrob. Agents Chemother. 39:1559-1564.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 1559-1564
-
-
Reedjik, M.1
Boucher, C.A.B.2
Van Bommel, T.3
Ho, D.D.4
Tzeng, T.B.5
Sereni, D.6
Veyssier, P.7
Jurriaans, S.8
Granneman, R.9
Hsu, A.10
Leonard, J.M.11
Danaer, S.A.12
-
18
-
-
0026318387
-
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture
-
Richman, D., C.-K. Shih, I. Lowy, J. Rose, P. Prodanovich, S. Goff, and J. Griffin. 1991. Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Proc. Natl. Acad. Sci. USA 88:11241-11245.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 11241-11245
-
-
Richman, D.1
Shih, C.-K.2
Lowy, I.3
Rose, J.4
Prodanovich, P.5
Goff, S.6
Griffin, J.7
-
19
-
-
0027374758
-
A short-term clinical evaluation of L-697.661, a non-nucleosidc inhibitor of HIV-1 reverse transcriptase
-
Saag, M. S., E. A. Emini, O. L. Laskin, J. Douglas, W. I. Lapidus, W. A. Schleif, R. J. Whitley, C. Hildebrand, V. W. Byrnes. J. C. Kappes, K. W. Anderson, F. E. Massari, G. M. Shaw and the L-697,661 Working Group. 1993. A short-term clinical evaluation of L-697.661, a non-nucleosidc inhibitor of HIV-1 reverse transcriptase. N. Engl. J. Med. 329:1065-1072.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1065-1072
-
-
Saag, M.S.1
Emini, E.A.2
Laskin, O.L.3
Douglas, J.4
Lapidus, W.I.5
Schleif, W.A.6
Whitley, R.J.7
Hildebrand, C.8
Byrnes, V.W.9
Kappes, J.C.10
Anderson, K.W.11
Massari, F.E.12
Shaw, G.M.13
-
20
-
-
0026409650
-
Low-dose zidovudine in combination with either acyclovir or lymphoblastoid interferon-alpha in asymptomatic HIV-infected patients: A pilot study
-
Weber, R., A. Bonetti, J. Jost, M. W. Vogt, B. Spacev, W. Siegenthaler. and R. Luthy. 1993. Low-dose zidovudine in combination with either acyclovir or lymphoblastoid interferon-alpha in asymptomatic HIV-infected patients: a pilot study. Infection 19:395-400.
-
(1993)
Infection
, vol.19
, pp. 395-400
-
-
Weber, R.1
Bonetti, A.2
Jost, J.3
Vogt, M.W.4
Spacev, B.5
Siegenthaler, W.6
Luthy, R.7
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