Central nervous system relapse after bone marrow transplantation for acute leukemia in first remission

Bone Marrow Transplantation

Volumn 17, Issue 4, 1996, Pages 637-641

  Singhal, S ^a   Powles, R ^a   Treleaven, J ^a   Horton, C ^a   Tait, D ^a   Meller, S ^a   Pinkerton, C R ^a   Mehta, J ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

Acute lymphoblastic leukemia; Acute myeloid leukemia; Central nervous system leukemia; Cranial irradiation; Craniospinal irradiation; Intrathecal chemotherapy

Indexed keywords

METHOTREXATE;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BLEEDING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CENTRAL NERVOUS SYSTEM INFECTION; CENTRAL NERVOUS SYSTEM TUMOR; CHILD; FEMALE; HUMAN; INTRATHECAL DRUG ADMINISTRATION; LEUKEMIA REMISSION; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; WHOLE BODY RADIATION;

ACTUARIAL ANALYSIS; ACUTE DISEASE; ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW TRANSPLANTATION; CEREBROSPINAL FLUID; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CRANIAL IRRADIATION; CYTARABINE; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; HYDROCORTISONE; INJECTIONS, SPINAL; LEUKEMIA; LEUKEMIC INFILTRATION; MALE; MENINGES; METHOTREXATE; PROSPECTIVE STUDIES; RECURRENCE; REMISSION INDUCTION; RISK; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION;

EID: 0030008002     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Thompson CB, Sanders JE, Flournoy N et al. The risks of central nervous system relapse and leukoencephalopathy in patients receiving marrow transplants for acute leukemia. Blood 1986; 67: 195-199.
2. Ganem G, Kuentz M, Bernaudin F et al. Central nervous system relapses after bone marrow transplantation for acute lymphoblastic leukemia in remission. Cancer 1989; 64: 1796-1804.
3. Tiley C, Powles R, Treleaven J et al. Feasibility and efficacy of maintenance chemotherapy following autologous bone marrow transplantation for first remission acute lymphoblastic leukaemia. Bone Marrow Transplant 1993;12: 449-455.
4. Powles R, Mehta J, Singhal S et al. Autologous bone marrow or peripheral blood stem cell transplantation followed by maintenance chemotherapy for adult acute lymphoblastic leukemia in first remission: 50 cases from a single center. Bone Marrow Transplant 1995; 16: 241-247.
5. Mehta J, Powles R, Singhal S et al. Sequential high-dose therapy of adult acute lymphoblastic leukemia: role of maintenance chemotherapy after peripheral blood stem cell transplantation in first remission. In: Dicke KA, Keating A (eds). Autologous Marrow and Blood Transplantation. Proceedings of the Seventh International Symposium, Arlington, Texas, The Cancer Treatment Research and Educational Institute, 1995, pp. 135-144.
6. Helenglass G, Powles RL, McElwain TJ et al. Melphalan and total body irradiation (TBI) versus cyclophosphamide and TBI as conditioning for allogeneic matched sibling bone marrow transplants for acute myeloblastic leukaemia in first remission. Bone Marrow Transplant 1988; 3: 21-29.
7. Mehta J, Powles RL, Mitchell P et al. Graft failure after bone marrow transplantation from unrelated donors using busulphan and cyclophosphamide for conditioning. Bone Marrow Transplant 1994; 13: 583-587.
8. Mehta J, Powles R. Treleaven J et al. Melphalan versus cyclophosphamide with total body irradiation as conditioning for allogeneic bone marrow transplantation in first remission acute myeloid leukemia. Blood 1994; 84(Suppl. 1): 714a.
9. Mehta J, Powles R, Singhal S et al. Autologous bone marrow transplantation for acute myeloid leukemia in first remission: identification of modifiable prognostic factors. Bone Marrow Transplant 1995; 16: 499-506.
10. Dunlop LC, Powles R, Singhal S et al. Bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. Bone Marrow Transplant 1996; 17: 365-370.