Hypertonie activation and recovery of system a amino acid transport in renal MDCK cells

American Journal of Physiology

Volumn 270, Issue 3 PART 2, 1996, Pages

  Chen, Jie Guang ^a,b   Coe, Mark ^a   McAteer, James A ^a   Kempson, Stephen A ^a  

^a INDIANA UNIVERSITY   (United States)

^b Medical Sciences 374 ^*  (United States)

Author keywords

Alanine; Betaine; Carbon 14 labeled u methylaminoisobutyric acid; Kidney; Madin darby canine kidney cells; Osmoregulation

Indexed keywords

4 AMINOBUTYRIC ACID; CYCLOHEXIMIDE; DACTINOMYCIN; HYPERTONIC SOLUTION; PUROMYCIN;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; DOG; DOWN REGULATION; INTRACELLULAR TRANSPORT; NONHUMAN; OSMOREGULATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION;

AMINO ACIDS; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; DOGS; HYPERTENSION, RENAL; KIDNEY; WATER-ELECTROLYTE BALANCE;

EID: 0030007992     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Bagnasco, S., R. Balaban, H. M. Fales, Y. M. Yang, and M. Burg. Predominant osmotically active organic solutes in rat and rabbit renal medullas. J. Biol. Chem. 261: 5872-5877, 1986.
2. Bedford, J. J., and J. P. Leader. The effect of hyperosmolarity on the free amino acid content of cultured kidney cells (MDCK) (Abstract). FASEBJ. 1: A812,1993.
3. Boerner,P., and M. H. Saier. Adaptive regulatory control of system A transport activity in a kidney epithelial cell line (MDCK) and in a transformed variant (MDCK-T1). J. Cell Physiol. 122: 308-315, 1985.
4. Burg, M. B., and A. Garcia-Perez. How tonicity regulates gene expression. J. Am. Soc. Nephrol. 3: 121-127, 1992.
5. Chen, J. G., L. R. Klus, D. K. Steenbergen, and S. A. Kempson. Hypertonie upregulation of amino acid transport system A in vascular smooth muscle cells. Am. J. Phvsiol. 267 (CellPhysiol. 36): C529-C536, 1994.
6. Chen, J. G., and S. A. Kempson. Osmoregulation of neutral amino acid transport. Proc. Soc. Exp. Biol. Med. 210: 1-6, 1995.
7. Christensen, H. N. Role of amino acid transport and countertransport in nutrition and metabolism. Physio!. Rev. 70: 43-77. 1990.
8. Cohen, D. M., J. C. Wasserman, and S. R. Gullans. Immediate early gene and HSP70 expression in hyperosmotic stress in MDCK cells. An;. -J. Physiol. 261 (Cell Physiol. 30): C594-C601. 1991.
9. Collarini, E. J., and D. L. Oxender. Mechanisms of transport of amino acids across membranes. Anna. Rev. Nittr. 7: 75-90, 1987.
10. Englesberg, E., and J. Moffett. A genetic approach to the study of neutral amino acid transport in mammalian cells in culture. J. Membr. Biol. 91: 199-212, 1986.
11. Garner, M. M., and M. B. Burg. Macromolecular crowding and confinement in cells exposed to hypertonicity. Am. J. Physiol. 266 (Cell. Physiol. 35): C877-C892, 1994.
12. Gullans, S. R., J. D. Blumenfeld, J. A. Baischi, M. Kaleta, R. M. Brenner, C. W. Heilig, and S. C. Hebert. Accumulation of major organic osmolytes in rat renal inner medulla in dehydration. Am. J. Physiol. 255 (Renal Fluid Electrolyte PhysioJ. 24): F626-F634, 1988.
13. Handler, J. S., and H. M. Kwon. Regulation of renal cell organic osmolyte transport by tonicity. Am. J. Physiol. 256 (Cell Physiol. 25): C1449-C1451, 1993.
14. Handlogten, M. E., E. F. Barber, D. S. Bracy, and M. S. Kilberg. Amino acid-dependent inactivation of glucagon-induced system A transport activity in cultured rat hepatocytes. Mol. Cell. Endocnnol. 43: 61-69, 1985.
15. Handlogten, M. E., and M. S. Kilberg. Induction and decay of amino acid transport in the liver. J. Biol. Chem. 259: 3519-3525, 1984.
16. Jones, M., R. S. Gupta, and E. Englesberg. Enhancement in amount of PI (hsp60) in mutants of Chinese hamster ovary iCHO-KDcells exhibiting increases in the A system of amino acid transport. Proc. Natl. Acad. Sei. USA 91: 858-862, 1994.
17. Kilberg, M. S. System A-mediated amino acid transport: metabolic control at the plasma membrane. Trends Biochem. Sei. 11: 183-186, 1986.
18. Kilberg, M. S., B. R. Stevens, and D. A. Novak. Recent advances in mammalian amino acid transport. Annii. Rev. Nutr. 13: 137-165, 1993.
19. Law, R. O. Alterations in renal inner medullary levels of amino nitrogen during acute water diuresis and hypovolaemic oliguria in rats. PfluegersArch. 418: 442-446, 1991.'
20. Law, R. O., and D. P. J. Turner. Are ninhydrin-positive substances volume regulatory osmolytes in rat renal papillary cells. J. Physiol. Land. 386: 45-61, 1987.
21. Moffett, J., and E. Englesberg. Recessive constitutive mutant Chinese hamster ovary cells (CHO-K1) with an altered A system for amino acid transport and the mechanism of gene regulation of the A system. Mol, Cell. Biol. 4: 799-808, 1984.
22. Moriyama, T., A. Garcia-Perez, A. D. Olson, and M. B. Burg. Intracellular betaine substitutes for sorbitol in protecting renal medullary cells from hypertonicity. Am. J. Physiol. 260 (Renal Fluid Electrolyte Physiol. 29): F494-F497, 1991.
23. Nakanishi, T., R. J. Turner, and M. B. Burg. Osmoregulatory changes in myo-inositol transport by renal cells. Proc. Natl. Acad. Sei. USA 86: 6002-6006,1989.
24. Nakanishi, T., R. J. Turner, and M. B. Burg. Osmoregulation of betaine transport in mammalian renal medullary cells. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1061-F1067, 1990.
25. Nakanishi, T., O. Uyama, and M. Sugita. Osmotically regulated taurine content in rat renal inner medulla. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F957-F962, 1991.
26. Olea, R. S., H. Pasantes-Morales, A. Lazaro, and M. Cereijido. Osmolarity-sensitive release of free amino acids from cultured kidney cells (MDCK). J. Membr. Biol. 121: 1-9,1991.
27. Petronini, P. G., E. D. Angelis, A. F. Borghetti, and K. P. Wheeler. Osmotically inducible uptake of betaine via amino acid transport system Ain SV-3T3 cells. Biochem. J. 300: 45-50, 1994.
28. Rasmusson, R. L., D. G. Davis, and M. Lieberman. Amino acid loss during volume regulatory decrease in cultured chick heart cells. Am. J. Physiol. 264 (Cell Physiol. 33): C136-C145, 1993.
29. Ruiz-Montasell, B., M. Gomez-Angelats, F. J. Casado, A. Felipe, J. D. McGivan, and M. Pastor-Anglada. Evidence for a regulatory protein involved in the increased activity of system A for neutral amino acid transport in osmotically stressed mammalian cells. Proc. Natl. Acad. Sei. USA 91: 9569-9573, 1994.
30. Sheikh-Hamad, D., A. Garcia-Perez, J. D. Ferraris, E. M. Peters, and M. B. Burg. Induction of gene expression by heat shock versus osmotic stress. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F28-F34,1994.
31. Uchida, S., A. Garcia-Perez, H. Murphy, and M. B. Burg. Signal for induction of aldose reductase in renal medullary cells by high external NaCl. Am. J. Physiol. 256 (Cell Physiol. 25): C614-C620,1989.
32. Yamauchi, A., A. Miyai, K. Yokoyama, T. Itoh, T. Kainada, N. Ueda, and Y. Fujiwara. Response to osmotic stimuli in mesangial cells: role of system A transporter. Am. J. Physiol. 267 (Cell Physiol. 36): C1493-C1500,1994.
33. Yamauchi, A., S. Uchida, H. M. Kwon, A, S. Preston, R. B. Robey, A. Garcia-Perez, M. B. Burg, and J. S. Handler. Cloning of a Na+ and Cl~-dependent betaine transporter that is regulated by hypertonicity. J. Biol. Chem. 267: 649-652,1992.
34. Yancey, P. H., M. E. Clark, S. C. Hand, R. D. Bowlus, and G. N. Somero. Living with water stress: evolution of osmolyte systems. Science Wash. DC 217: 1214-1222, 1982.