High-dose recombinant endotoxin neutralizing protein improves survival in rabbits with Escherichia coli sepsis

Critical Care Medicine

Volumn 24, Issue 7, 1996, Pages 1203-1207

  Saladino, Richard A ^a   Stack, Anne M ^a   Thompson, Claudette ^b   Sattler, Felicia ^b   Novitsky, Thomas J ^c   Siber, George R ^b   Fleisher, Gary R ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Associates of Cape Cod Inc   (United States)

Author keywords

animal model; bacterial infection; critical illness; cytokine; endotoxin; endotoxin neutralizing protein; lipopolysaccharide; shock, septic; tumor necrosis factor

Indexed keywords

CYTOKINE; ENDOTOXIN; LIPOPOLYSACCHARIDE; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CRITICAL ILLNESS; DOSE CALCULATION; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; RABBIT; SEPSIS; SURVIVAL;

ANIMALS; ANTI-INFECTIVE AGENTS; ENDOTOXINS; ESCHERICHIA COLI INFECTIONS; HORSESHOE CRABS; INVERTEBRATE HORMONES; LIPOPOLYSACCHARIDES; MALE; RABBITS; RECOMBINANT PROTEINS; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030007745     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199607000-00023     Document Type: Article

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