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Volumn 62, Issue 2, 1996, Pages 278-283

Attenuation of multiple organ dysfunction in a chronic sheep model by the 21-aminosteroid U74389G

Author keywords

[No Author keywords available]

Indexed keywords

21 AMINOSTEROID; 21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE;

EID: 0030007440     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0208     Document Type: Article
Times cited : (16)

References (32)
  • 1
    • 0014471267 scopus 로고
    • Mechanism of the protective effect of corticosteroids in hemorrhagic shock
    • Lefer, A. M., and Martin, J. Mechanism of the protective effect of corticosteroids in hemorrhagic shock. Am. J. Physiol. 216: 314, 1969.
    • (1969) Am. J. Physiol. , vol.216 , pp. 314
    • Lefer, A.M.1    Martin, J.2
  • 2
    • 0015867442 scopus 로고
    • Possible mechanism of the beneficial action of glucocorticoids in circulatory shock
    • Spath, J. A., Gorczynski, R. J., and Lefer, A. M. Possible mechanism of the beneficial action of glucocorticoids in circulatory shock. Surg. Gynecol. Obstet. 137: 567, 1973.
    • (1973) Surg. Gynecol. Obstet. , vol.137 , pp. 567
    • Spath, J.A.1    Gorczynski, R.J.2    Lefer, A.M.3
  • 3
    • 0023837670 scopus 로고
    • New 21-aminosteroid antioxidant lacking glucocorticoid activity stimulates adrenocorticotropin secretion and blocks arachidonic acid release from mouse pituitary tumor (AtT-20) cells
    • Braughler, J. M., Chase, R. L., and Neff, G. L. New 21-aminosteroid antioxidant lacking glucocorticoid activity stimulates adrenocorticotropin secretion and blocks arachidonic acid release from mouse pituitary tumor (AtT-20) cells. J. Pharmacol. Exp. Ther. 244: 423, 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 423
    • Braughler, J.M.1    Chase, R.L.2    Neff, G.L.3
  • 4
    • 0023610855 scopus 로고
    • Beneficial effects of the 21-aminosteroid U74006F in acute CNS trauma and hypovolemic shock
    • Hall, E. D. Beneficial effects of the 21-aminosteroid U74006F in acute CNS trauma and hypovolemic shock. Acta Anaesth. Belg. 38: 421, 1987.
    • (1987) Acta Anaesth. Belg. , vol.38 , pp. 421
    • Hall, E.D.1
  • 5
    • 0025133970 scopus 로고
    • Protective effects of a novel nonglucocorticoid 21-aminosteroid (U74006F) during traumatic shock in rats
    • Aoki, N., and Lefer, A. M. Protective effects of a novel nonglucocorticoid 21-aminosteroid (U74006F) during traumatic shock in rats. J. Cardiovasc. Pharmacol. 15: 205, 1990.
    • (1990) J. Cardiovasc. Pharmacol. , vol.15 , pp. 205
    • Aoki, N.1    Lefer, A.M.2
  • 6
    • 0027322774 scopus 로고
    • Attenuation of acute lung injury and oxygen radical production by the 21-aminosteroid, U-78518F
    • Tanigaki, T., Suzuki, Y., Heimer, D., Sussman, H. H., Ross, W. G., and Raffin, T. A. Attenuation of acute lung injury and oxygen radical production by the 21-aminosteroid, U-78518F. J. Appl. Physiol. 74: 2155, 1993.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 2155
    • Tanigaki, T.1    Suzuki, Y.2    Heimer, D.3    Sussman, H.H.4    Ross, W.G.5    Raffin, T.A.6
  • 7
    • 0023846372 scopus 로고
    • Attenuation of hemorrhagic shock by the nonglucocorticoid 21-aminosteroid U74006F
    • Hall, E. D., Yonkers, P. A., and McCall, J. M. Attenuation of hemorrhagic shock by the nonglucocorticoid 21-aminosteroid U74006F. Eur. J. Pharmacol. 147: 299, 1988.
    • (1988) Eur. J. Pharmacol. , vol.147 , pp. 299
    • Hall, E.D.1    Yonkers, P.A.2    McCall, J.M.3
  • 8
    • 0023341160 scopus 로고
    • Organ distribution pattern and plasma half-life times of diagnostically important enzymes in the sheep
    • Bickhardt, K. Organ distribution pattern and plasma half-life times of diagnostically important enzymes in the sheep. Berl. Munch. Tierärztl. Wochenschr. 100: 152, 1987.
    • (1987) Berl. Munch. Tierärztl. Wochenschr. , vol.100 , pp. 152
    • Bickhardt, K.1
  • 11
    • 0025918245 scopus 로고
    • Das multiorganversagen (MOV). Ausdruck eines generalisierten zellschadens aller organe nach schwerem trauma
    • Regel, G., Sturm, J. A., Pape, H. C., Gratz, K. F., and Tscherne, H. Das Multiorganversagen (MOV). Ausdruck eines generalisierten Zellschadens aller Organe nach schwerem Trauma. Unfallchirurg 94: 487, 1991.
    • (1991) Unfallchirurg , vol.94 , pp. 487
    • Regel, G.1    Sturm, J.A.2    Pape, H.C.3    Gratz, K.F.4    Tscherne, H.5
  • 12
    • 0025945145 scopus 로고
    • Das leberversagen als teil eines multiorganversagens nach polytrauma
    • Seekamp, A., Regel, G., Sturm, J. A., and Tscherne, H. Das Leberversagen als Teil eines Multiorganversagens nach Polytrauma. Unfallchirurg 49: 502, 1991.
    • (1991) Unfallchirurg , vol.49 , pp. 502
    • Seekamp, A.1    Regel, G.2    Sturm, J.A.3    Tscherne, H.4
  • 13
    • 33747144099 scopus 로고
    • The gut origin septic state in blunt multiple trauma
    • Border, J. R., Hasset, J., and La Duca, J. The gut origin septic state in blunt multiple trauma. Ann. Surg. 206: 42, 1987.
    • (1987) Ann. Surg. , vol.206 , pp. 42
    • Border, J.R.1    Hasset, J.2    La Duca, J.3
  • 14
    • 0002015746 scopus 로고
    • Gut failure: Its role in multiple organ failure syndrome
    • E. A. Deitch (Ed.), New York: Thieme Medical Publishers Inc.
    • Deitch, E. A. Gut failure: Its role in multiple organ failure syndrome. In E. A. Deitch (Ed.), Multiple Organ Failure: Pathophysiology and Basic Concepts of Therapy. New York: Thieme Medical Publishers Inc., 1990. Pp. 40-59.
    • (1990) Multiple Organ Failure: Pathophysiology and Basic Concepts of Therapy. , pp. 40-59
    • Deitch, E.A.1
  • 15
    • 0023610148 scopus 로고
    • A new class of compounds for stroke and trauma: Effect of 21-aminosteroids on lipid peroxidation
    • McCall, J. M., Braughler, J. M., and Hall, E. D. A new class of compounds for stroke and trauma: effect of 21-aminosteroids on lipid peroxidation. Acta Anaesthesiol. Belg. 38: 417, 1987.
    • (1987) Acta Anaesthesiol. Belg. , vol.38 , pp. 417
    • McCall, J.M.1    Braughler, J.M.2    Hall, E.D.3
  • 16
    • 0023836392 scopus 로고
    • Effects of the 21-aminosteroid U74006F on experimental head injury in mice
    • Hall, E. D., Yonkers, P. A., McCall, J. M., and Braughler, J. M. Effects of the 21-aminosteroid U74006F on experimental head injury in mice. J. Neurosurg. 68: 456, 1988.
    • (1988) J. Neurosurg. , vol.68 , pp. 456
    • Hall, E.D.1    Yonkers, P.A.2    McCall, J.M.3    Braughler, J.M.4
  • 17
    • 0028187682 scopus 로고
    • Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage
    • Hall, E. D., McCall, J. M., and Means, E. D. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv. Pharmacol. 28: 221, 1994.
    • (1994) Adv. Pharmacol. , vol.28 , pp. 221
    • Hall, E.D.1    McCall, J.M.2    Means, E.D.3
  • 19
    • 0025264383 scopus 로고
    • Protective effect of a novel 21-aminosteroid during splanchnic artery occlusion shock. Circ
    • Ill, G. J., and Lefer, A. M. Protective effect of a novel 21-aminosteroid during splanchnic artery occlusion shock. Circ. Shock 30: 155, 1990.
    • (1990) Shock , vol.30 , pp. 155
    • Ill, G.J.1    Lefer, A.M.2
  • 20
    • 0023743182 scopus 로고
    • Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs
    • Natale, J. E., Schott, R. J., Hall, E. D., Braughler, J. M., and D'Alecy, L. G. Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs. Stroke 19: 1371, 1988.
    • (1988) Stroke , vol.19 , pp. 1371
    • Natale, J.E.1    Schott, R.J.2    Hall, E.D.3    Braughler, J.M.4    D'Alecy, L.G.5
  • 21
    • 0028032172 scopus 로고
    • Protective effect of the lazaroid U74006F in cold ischemia-reperfusion injury of the liver
    • Cosenza, C. A., Cramer, D. V., Cunneen, S. A., Tuso, P. J., Wang, H. K., and Makowka, L. Protective effect of the lazaroid U74006F in cold ischemia-reperfusion injury of the liver. Hepatology 19: 418, 1994.
    • (1994) Hepatology , vol.19 , pp. 418
    • Cosenza, C.A.1    Cramer, D.V.2    Cunneen, S.A.3    Tuso, P.J.4    Wang, H.K.5    Makowka, L.6
  • 23
    • 0026569561 scopus 로고
    • Splanchnic vascular endothelial dysfunction in rat endotoxemia: Role of superoxide radicals
    • Siegfried, M. R., Ma, X., and Lefer, A. M. Splanchnic vascular endothelial dysfunction in rat endotoxemia: Role of superoxide radicals. Eur. J. Pharmacol. 212: 171, 1992.
    • (1992) Eur. J. Pharmacol. , vol.212 , pp. 171
    • Siegfried, M.R.1    Ma, X.2    Lefer, A.M.3
  • 24
  • 25
    • 0025687478 scopus 로고
    • Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo
    • Jaeschke, H., Farhood, A., and Smith, C. W. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB 4: 3355, 1990.
    • (1990) FASEB , vol.4 , pp. 3355
    • Jaeschke, H.1    Farhood, A.2    Smith, C.W.3
  • 26
    • 0025756580 scopus 로고
    • Neutrophil and Kupffer cell-induced oxydant stress and ischemia-reperfusion injury in rat liver
    • Jaeschke, H., and Farhood, A. Neutrophil and Kupffer cell-induced oxydant stress and ischemia-reperfusion injury in rat liver. Am. J. Physiol. 260: G355, 1991.
    • (1991) Am. J. Physiol. , vol.260
    • Jaeschke, H.1    Farhood, A.2
  • 28
    • 84948369684 scopus 로고
    • Bronchoalveolar lavage fluid and plasma proteins, chemiluminescence response and protein contents of polymorphonuclear leukocytes from blood and lavage fluid in polytraumatized patients
    • Dwenger, A., Schweitzer, G., and Regel, G. Bronchoalveolar lavage fluid and plasma proteins, chemiluminescence response and protein contents of polymorphonuclear leukocytes from blood and lavage fluid in polytraumatized patients. Clin. Chem. Clin. Biochem. 24: 73, 1986.
    • (1986) Clin. Chem. Clin. Biochem. , vol.24 , pp. 73
    • Dwenger, A.1    Schweitzer, G.2    Regel, G.3
  • 29
    • 0028141678 scopus 로고
    • Inhibition of neutrophil leukotrien generation by the 21-aminosteroid, U-74389F
    • Gadaleta, D., Verma, M., and Davis, J. M. Inhibition of neutrophil leukotrien generation by the 21-aminosteroid, U-74389F. J. Surg. Res. 57: 233, 1994.
    • (1994) J. Surg. Res. , vol.57 , pp. 233
    • Gadaleta, D.1    Verma, M.2    Davis, J.M.3
  • 30
    • 0025193924 scopus 로고
    • A 21-aminosteroid reduces hydrogen peroxide generation by and chemiluminescence of stimulated human leukocytes
    • Fisher, M., Levine, P. H., and Cohen, R. A. A 21-aminosteroid reduces hydrogen peroxide generation by and chemiluminescence of stimulated human leukocytes. Stroke 21: 1435, 1990.
    • (1990) Stroke , vol.21 , pp. 1435
    • Fisher, M.1    Levine, P.H.2    Cohen, R.A.3
  • 31
    • 0024337819 scopus 로고
    • Relationship between lung injury and lipid peroxidation caused by recurrent endotoxinemia
    • Demling, R., and LaLonde, C. Relationship between lung injury and lipid peroxidation caused by recurrent endotoxinemia. Am. Rev. Respir. Dis. 139: 1118, 1989.
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 1118
    • Demling, R.1    LaLonde, C.2
  • 32
    • 0025201481 scopus 로고
    • Antiinflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat
    • Knowles, R. G., Salter, M., Brookes, S. L., and Moncada, S. Antiinflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat. Biochem. Biophys. Res. Commun. 172: 1042, 1990.
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 1042
    • Knowles, R.G.1    Salter, M.2    Brookes, S.L.3    Moncada, S.4


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