Synthesis of alkynyl-substituted pyrrolidin-1-yloxyl radicals from 1-pyrroline N-oxide nitrones and alkynylmagnesium bromides

Synthesis

Volumn , Issue 2, 1996, Pages 204-208

  Bárácz, Nóra M ^a   Hankovszky, Olga H ^a   Sár, Cecília P ^a   Jerkovich, Gyula ^b   Hideg, Kálmán ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

^b Institute for Drug Research Budapest   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN RADICAL; PYRROLIDINE 1 OXYL DERIVATIVE; PYRROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; REACTION ANALYSIS;

EID: 0030007306     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1996-4199     Document Type: Article

References (15)

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2. Tufariello, J. J. In 1,3-Dipolar Cycloaddition Chemistry; Padwa, A., Ed.; Wiley-Interscience: New York, 1984. Ch. 9, pp 101-106. Torssell, K.G.B. Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis; VHC Publisher Inc.: Weinheim, 1988; pp 27-38. Breuer, E. In Nitrones, Nitronates and Nitroxides; Patai, S. and Rappoport, Z., Eds.; John Wiley and Sons: Chichester, 1989; pp 181-182 and 260-261. Balasubramanian, Z. Org. Prep. Proc. Int. 1985, 17, 23.
3. Tufariello, J. J. In 1,3-Dipolar Cycloaddition Chemistry; Padwa, A., Ed.; Wiley-Interscience: New York, 1984. Ch. 9, pp 101-106. Torssell, K.G.B. Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis; VHC Publisher Inc.: Weinheim, 1988; pp 27-38. Breuer, E. In Nitrones, Nitronates and Nitroxides; Patai, S. and Rappoport, Z., Eds.; John Wiley and Sons: Chichester, 1989; pp 181-182 and 260-261. Balasubramanian, Z. Org. Prep. Proc. Int. 1985, 17, 23.
4. Tufariello, J. J. In 1,3-Dipolar Cycloaddition Chemistry; Padwa, A., Ed.; Wiley-Interscience: New York, 1984. Ch. 9, pp 101-106. Torssell, K.G.B. Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis; VHC Publisher Inc.: Weinheim, 1988; pp 27-38. Breuer, E. In Nitrones, Nitronates and Nitroxides; Patai, S. and Rappoport, Z., Eds.; John Wiley and Sons: Chichester, 1989; pp 181-182 and 260-261. Balasubramanian, Z. Org. Prep. Proc. Int. 1985, 17, 23.
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9. CH (isoxazoline) = 4.62 (3-OAc), and 4.30 (4-OAc), respectively.
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