Heteroduplex generator in analysis of Rh blood group alleles

Clinical Chemistry

Volumn 42, Issue 3, 1996, Pages 356-360

  Stoerker, Jay ^a   Hurwitz, Carlyn ^a   Rose, Nancy C ^b   Silberstein, Leslie E ^b   Highsmith, W Edward ^c  

^a Avitech Diagnostics Inc   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

blood group incompatibilities; erythrocytes; fetal status; genetic variants; hemolytic disease of the newborn; immunology; newborns; pregnancy; serotype specific sequence variations

Indexed keywords

HETERODUPLEX; RHESUS ANTIGEN;

ALLELE; ARTICLE; GENE LOCATION; GENE LOCUS; GENETIC VARIABILITY; HUMAN; IMMUNOPHENOTYPING; NEWBORN HEMOLYTIC DISEASE; RHESUS INCOMPATIBILITY; SEQUENCE ANALYSIS; SEROTYPING;

EID: 0030007133     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/42.3.356     Document Type: Article

References (24)

1. Centers for Disease Control. Rh hemolytic disease - Connecticut, United States 1970-1979. MMWR CDC Surveill Summ 1981;30: 13-5
2. Chavez GF, Mulinare J, Edmonds LD. Epidemiology of Rh hemolytic disease of the newborn in the United States. JAMA 1991;265: 270-4.
3. ACOG Technical Bulletin, No. 148 Prevention of Rho(D) isoimmunization. Washington, DC: American College of Obstetrics and Gynecology, 1990.
4. Jackson GM, Branch DW. Isoimmunization in pregnancy. In: Gabbe SL, Niebyl JR, Simpson JL, eds. Obstetrics: normal and problem pregnancies, 2nd ed. New York: Churchill Livingstone, 1991:957-85.
5. Mollison PL. Haemolytic disease of the newborn. In: Mollison PL, Engelfriet CP, Contreras M, eds. Blood transfusion in clinical medicine, 8th ed. Oxford: Blackwell Scientific Publications, 1988: 640-9.
6. Le Van Kim C, Mouro I, Cherif-Zahar B, Raynal V, Cherrier C, Cartron J-P, Colin Y. Molecular cloning and primary structure of the human blood group Rh D polypeptide. Proc Natl Acad Sci U S A 1992;89:10925-9.
7. Bennett PR, Le Van Kim C, Colin Y, Warwick RM, Cherif-Zahar B, Fisk NM, Cartron J-P. Prenatal determination of fetal Rh D type by DNA amplification. N Engl J Med 1993;329:607-10.
8. Fisk NM, Bennett PR, Warwick RM, Cherif-Zahar B, Cartron J-P. Clinical utility of fetal Rh D typing in alloimmunized pregnancies by means of polymerase chain reaction on amniocytes or chorionic villi. Am J Obstet Gynecol 1994;171:50-4.
9. Spence WC, Maddalena A, Demers DB, Bick DP. Molecular analysis of the Rh D genotype in fetuses at risk for Rh D hemolytic disease. Obstet Gynecol 1995;85:296-8.
10. Chaing SH, Colins ML, Silverman LM. Genotyping of Rh antigens by molecular genetic method [Abstract]. Clin Chem 1995;41: S108.
11. Wolter LC, Hyland CA, Saul A. Refining the DNA polymorphisms that associate with the rhesus c phenotype [Letter]. Blood 1994; 84:985-6.
12. Daniels G. Hot spots in the red cell membrane: molecular aspects of some cell antigens. Immunol Invest 1995;24:199-212.
13. Rouillac C, Colin Y, Hughes-Jones NC, Beolet M, D'Ambrosio A-M, Cartron J-P, Le Van Kim C. Transcript analysis of category phenotypes predicts hybrid Rh D-CE-D proteins associated with alterations of D epitopes. Blood 1995;85:2937-44.
14. Cotton RGH. Detection of mutations in DNA. Curr Opin Biotechnol 1992;3:24-30.
15. Keen J, Lester D, Ingelhern C, Curtis A, Bahattacharya S. Rapid detection of single base mismatches as heteroduplexes on hydrolink gels. Trends Genet 1991;7:5-6.
16. Soto D, Sukamar S. Improved detection of mutations in the p53 gene in human tumors as single strand conformation polymorphs and double strand heteroduplex polymorphisms. PCR Methods Appl 1992;2:96-8.
17. Highsmith WE. Carrier screening for cystic fibrosis. Clin Chem 1993;39:706-7.
18. Prior TW, Papp AC, Snyder PJ, Burghes AHM, Bartolo C, Sedra MS, et al. A missense mutation in the dystrophin gene in a muscular dystrophy patient. Nature Genet 1993;4:357-60.
19. Battacharyya A, Lilley DMJ. Single base mismatches in DNA. J Mol Biol 1989;209:583-97.
20. Battacharyya A, Lilley DMJ. The contrasting structures of mismatched DNA sequences containing looped-out bases (bulges) and multiple mismatches (bubbles). Nucleic Acids Res 1989;17: 6821-40
21. Wood N, Tyfield L, Bidwell J. Rapid classification of phenylketonuria genotypes by analysis of heteroduplexes generated by PCR-amplifiable synthetic DNA. Hum Mutat 1993;2:131-7.
22. Wood N, Standen GR, Murray EW, Bradley B, Bidwell J. Rapid genotype analysis in type 2B von Willebrand's disease using a universal heteroduplex generator. Br J Haematol 1995;89: 152-6.
23. Doherty T, Connell J, Stoerker J, Markham N, Shroyer AL, Shroyer KR. Analysis of clonality by polymerase reaction for PGK-1. Heteroduplex generator. Diagn Mol Pathol 1995:4:182-90.
24. Sarkar G, Sommer SS. The "megaprimer" method of site-directed mutagenesis. Biotechniques 1990;8:404-7.