A facile synthesis of 4-aryl-2,3-dihydropyrroles

Tetrahedron Letters

Volumn 37, Issue 23, 1996, Pages 3947-3950

  Busacca, Carl A ^a   Dong, Yong ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRROLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030006938     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00749-6     Document Type: Article

References (20)

1. a) Stevens, R.V.; Wentland, M.P. J. Am. Chem. Soc. 1968, 90, 5580-5583.
2. b) Stevens, R.V.; DuPree, L.E. Jr.; Lowenstein, P.L. J. Org. Chem. 1972, 37(7), 977-982.
3. c) Matsumura, Y.; Terauchi, J.; Yamamoto, T.; Konno, T.; Shono, T. Tetrahedron 1993, 49(38), 8503-8512.
4. a) Rawal, V.H.; Iwasa, S. J. Org. Chem. 1994, 59(10), 2685-2686.
5. b) Rawal, V.H.; Michoud, C.; Monestel, R.F. J. Am. Chem. Soc. 1993, 115, 3030-3031.
6. Shono, T.; Terauchi, J.; Matsumura, Y. Chem. Lett. 1989, 1963-1966.
7. Pinnick, H.W.; Kochhar, K.S. Tetrahedron Lett. 1983, 24(44), 4785-4788.
8. Sanchez, I.H.; Larraza, M.I.; Flores, H.J.; Rojas, I.; Alcala, R. Syn. Comm. 1983, 13(1), 35.
9. Clark, R.D.; Jahangir. Tetrahedron 1993, 49(7), 1351-1356.
10. Heck, R.F. Palladium Reagents in Organic Synthesis; Academic Press: San Diego, 1985.
11. for reviews see a) Ojima, I. Advances in Metal-Organic Chemistry, Volume 1; Liebeskind, L. S. Ed.; JAI Press: Greenwich, CT, 1988, p.51-97.
12. b) Himmele, W.; Siegel, H. Angew. Chem. Int. Ed. Engl. 1980, 19, 178-183.
13. a) Ojima, I.; Zhang, Z. J. Org. Chem. 1988, 53(18), 4422-4425.
14. b) Ojima, I. ; Tzamarioudaki, M.; Eguchi, M. J. Org. Chem. 1995, 60(22), 7078-7079.
15. Arcadi, A.; Bernocchi, E.; Cacchi, S.; Caglioti, L.; Marinelli, F. Tetrahedron Lett. 1990, 31(17), 2463-2466.
16. a) Jeffery, T. J. Chem. Soc. Chem. Comm. 1984, 1287-1289.
17. b) Larock, R.C.; Babu, S. Tetrahedron Lett. 1987, 28(44), 5291-5294.
18. Busacca, C.A.; Johnson, R.E.; Swestock, J. J. Org. Chem. 1993, 58(12), 3299-3303.
19. 1; R factor 4.2%.
20. 2S: C, 64.33; H, 5.08; N, 4.41; S, 10.10. Found: C, 64.36; H, 5.04; N, 4.27; S, 9.93. (formula presented)