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Volumn 118, Issue 5, 1996, Pages 1221-1222

Evidence for the photosensitized formation of singlet oxygen by UVB irradiation of 2′-deoxyguanosine 5′-monophosphate

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGUANOSINE PHOSPHATE;

EID: 0030006313     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9519187     Document Type: Article
Times cited : (36)

References (35)
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    • 7,11 We presume that the ratio observed here reflects the fact that singlet oxygen is being formed in the proximity of dGMP as well as the possible contribution of photoionization processes in the nucleotide's degradation (see below).
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    • 23 and/or competitive singlet oxygen sensitized oxidation of amino acids of SOD, as noted by one of the referees.
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    • 27 which are not created by the dGuo radical cation. To date there is no evidence for the presence of the 4R* and 4S* products in the reaction mixture resulting from the direct photolysis of dGuo (J. Cadet, private communication). We find no published reports of analogous studies involving the direct irradiation of dGMP.
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    • 28 report that the low-temperature irradiation of GMP in an inert atmosphere produces a species which absorbs at 305 nm; however, the product reverts to GMP upon warming of the photolysate to ambient temperature and must therefore be structurally different from that which we are observing.


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