Molecular variant of 5,10-methylenetetrahydrofolate reductase is a risk factor of ischemic heart disease in the Japanese population [1]

Atherosclerosis

Volumn 121, Issue 2, 1996, Pages 293-294

  Izumi, M ^a   Iwai, N ^a   Ohmichi, N ^a   Nakamura, Y ^a   Shimoike, H ^a   Kinoshita, M ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOCYSTEINE; METHYLENETETRAHYDROFOLIC ACID;

GENETIC VARIABILITY; HUMAN; ISCHEMIC HEART DISEASE; LETTER; PRIORITY JOURNAL; RISK FACTOR;

EID: 0030006275     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(95)05764-1     Document Type: Letter

References (5)

1. DEL Wilcken B Wilcken The pathogenesis of coronary artery disease: a possible role for methionine metabolism J Clin Invest 57 1976 1079 1082
2. SH Mudd Vascular disease and homocysteine metabolism N Engl J Med 313 1985 751 753
3. SS Kang PW Wong A Susmano J Sora M Norisis N Ruggie Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease Am J Hum Genet 48 1991 536 545
4. SS Kang EL Passen N Ruggie PWK Wong H Sora Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease Circulation 88 1993 1463 1469
5. P Frosst HJ Bloom P Goyette CA Sheppard RG Mattews GJH Boers M den Heijer LAJ Kluijtmans LP van den Heuvel R Rozen A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Nat Genet 10 1995 111 113