Effect of nucleotide substrate binding on the pK(a) of catalytic residues in barnase

Proteins: Structure, Function and Genetics

Volumn 25, Issue 2, 1996, Pages 180-194

  Gordon Beresford, Roland M H ^a   Van Belle, Daniel ^a   Giraldo, Jesús ^b   Wodak, Shoshana J ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

enzyme catalysis; microbial RNases; modeling; pK(a) shift; protein nucleic acid interaction

Indexed keywords

BACTERIAL ENZYME; RIBONUCLEASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THERMODYNAMICS;

CATALYSIS; GLUTAMINE; HISTIDINE; HYDROGEN-ION CONCENTRATION; ISOELECTRIC POINT; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEOTIDES; PROTEIN CONFORMATION; RIBONUCLEASES; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0030006073     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(199606)25:2<180::AID-PROT4>3.0.CO;2-M     Document Type: Article

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