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Volumn 156, Issue 10, 1996, Pages 4059-4066

Immunization with short peptides from the sequence of the systemic lupus erythematosus-associated 60-kDa Ro autoantigen results in anti-Ro ribonucleoprotein autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; RIBONUCLEOPROTEIN; RO 274; RO 413; RO 480; RO 500; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

EID: 0030005838     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (74)

References (51)
  • 1
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham, R E , L. Brean, and P. B. Medawar. 1953 Actively acquired tolerance of foreign cells. Nature 172:603.
    • (1953) Nature , vol.172 , pp. 603
    • Billingham, R.E.1    Brean, L.2    Medawar, P.B.3
  • 2
    • 0001642715 scopus 로고
    • Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance
    • Billingham, R. E , L. Brent, and P. B. Medawar 1956. Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance. Proc. Natl. Acad. Sci. USA 238:357.
    • (1956) Proc. Natl. Acad. Sci. USA , vol.238 , pp. 357
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 4
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler, J. W , N. Roehm, and P Marrack. 1987. T cell tolerance by clonal elimination in the thymus Cell 49:273
    • (1987) Cell , vol.49 , pp. 273
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 6
    • 0023161666 scopus 로고
    • T-cell unresponsiveness m vivo and in vitro: Fine specificity of induction and molecular characterization of the unresponsive state
    • Jenkins, M. K , D. M. Pardoll, J. Mizuguchi, H. Quill, and R. H. Schwartz. 1987. T-cell unresponsiveness m vivo and in vitro: fine specificity of induction and molecular characterization of the unresponsive state. Immunol. Rev. 95:113.
    • (1987) Immunol. Rev. , vol.95 , pp. 113
    • Jenkins, M.K.1    Pardoll, D.M.2    Mizuguchi, J.3    Quill, H.4    Schwartz, R.H.5
  • 7
    • 0024398589 scopus 로고
    • T cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II, I-E
    • Burkly, L. C., D. Lo, O. Kanagawa, R. L. Brinster, and R. A. Flavell. 1989. T cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II, I-E. Nature 342:564.
    • (1989) Nature , vol.342 , pp. 564
    • Burkly, L.C.1    Lo, D.2    Kanagawa, O.3    Brinster, R.L.4    Flavell, R.A.5
  • 8
    • 0024976414 scopus 로고
    • Tolerance of class I histocompatibility antigens expressed extrathymically
    • Morahan, G , J Allison, and J F. A P. Miller. 1989. Tolerance of class I histocompatibility antigens expressed extrathymically. Nature 339.622.
    • (1989) Nature , vol.339 , pp. 622
    • Morahan, G.1    Allison, J.2    Miller, J.F.A.P.3
  • 9
    • 0024332177 scopus 로고
    • Immunological tolerance then and now: Was the Medawar school right?
    • Nossal, G. J V. 1989. Immunological tolerance then and now: was the Medawar school right? Immunology 2(Suppl.):2
    • (1989) Immunology , vol.2 , Issue.SUPPL. , pp. 2
    • Nossal, G.J.V.1
  • 10
    • 0024376971 scopus 로고
    • Central versus peripheral tolerance: Clonal inactivation versus suppressor T cells, the second half of the thirty years war
    • Sercerz, E., A Oki, and G Gammon. 1989. Central versus peripheral tolerance: clonal inactivation versus suppressor T cells, the second half of the thirty years war. Immunology 2(Suppl):9.
    • (1989) Immunology , vol.2 , Issue.SUPPL. , pp. 9
    • Sercerz, E.1    Oki, A.2    Gammon, G.3
  • 11
    • 0015172562 scopus 로고
    • Infectious immunological tolerance
    • Gershon, R. K., and K Konda. 1971. Infectious immunological tolerance. Immunology 21.903.
    • (1971) Immunology , vol.21 , pp. 903
    • Gershon, R.K.1    Konda, K.2
  • 12
    • 0021833854 scopus 로고
    • Repertoire of T cells directed against a large protein antigen, beat-galactosidase. II. Only certain T helper or T suppressor cells are relevant in particular regulatory interactions
    • Krzych, U , A. V. Fowler, and E. E Sercarz. 1985. Repertoire of T cells directed against a large protein antigen, beat-galactosidase. II. Only certain T helper or T suppressor cells are relevant in particular regulatory interactions. J. Exp. Med. 162:311.
    • (1985) J. Exp. Med. , vol.162 , pp. 311
    • Krzych, U.1    Fowler, A.V.2    Sercarz, E.E.3
  • 13
    • 0021812663 scopus 로고
    • T cell tolerance studied at the level of antigenic determinates. I Latent reactivity to lysozyme peptides that lack suppressogenic epitopes can be revealed in lysozyme-tolerant mice
    • Oki, A., and E. E. Sercarz. 1985. T cell tolerance studied at the level of antigenic determinates. I Latent reactivity to lysozyme peptides that lack suppressogenic epitopes can be revealed in lysozyme-tolerant mice J. Exp. Med. 161:897
    • (1985) J. Exp. Med. , vol.161 , pp. 897
    • Oki, A.1    Sercarz, E.E.2
  • 14
    • 0018366767 scopus 로고
    • Amputation of a suppressor determinant on lysozyme reveals underlying T cell reactivity to other determinates
    • Yowell, R. L , B. A. Araneo, A. Miller, and E. E Sercarz. 1979. Amputation of a suppressor determinant on lysozyme reveals underlying T cell reactivity to other determinates. Nature 279:70.
    • (1979) Nature , vol.279 , pp. 70
    • Yowell, R.L.1    Araneo, B.A.2    Miller, A.3    Sercarz, E.E.4
  • 15
    • 0025131417 scopus 로고
    • SnRNPs and scRNPs as autoantigens clues to the etiologic etiology of connective tissue diseases
    • Craft, J , M Mamula, Y. Ohosone, G. Boire, H. Gold, and J. Hardin 1990. SnRNPs and scRNPs as autoantigens clues to the etiologic etiology of connective tissue diseases. Clin. Rheumatol. 9.10.
    • (1990) Clin. Rheumatol. , vol.9 , pp. 10
    • Craft, J.1    Mamula, M.2    Ohosone, Y.3    Boire, G.4    Gold, H.5    Hardin, J.6
  • 16
    • 0028908106 scopus 로고
    • Self-peptides in the initiation of lupus autoimmunity
    • Bockenstedt, L K , R. J. Gee, and M. J. Mamula. 1995. Self-peptides in the initiation of lupus autoimmunity. J. Immunol 154.3516.
    • (1995) J. Immunol , vol.154 , pp. 3516
    • Bockenstedt, L.K.1    Gee, R.J.2    Mamula, M.J.3
  • 17
    • 0023651203 scopus 로고
    • Molecular mimicry and autoimmune disease
    • Oldstone, M. B. A. 1987 Molecular mimicry and autoimmune disease Cell 50:819.
    • (1987) Cell , vol.50 , pp. 819
    • Oldstone, M.B.A.1
  • 18
    • 0026323566 scopus 로고
    • Autoantigenicity of Ro/SSA antigen is related to a nucleocapsid protein of vesicular stomatitis virus
    • Scofield, R. H., and J. B. Harley. 1991. Autoantigenicity of Ro/SSA antigen is related to a nucleocapsid protein of vesicular stomatitis virus. Proc. Natl. Acad. Sci. USA 88:3343
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3343
    • Scofield, R.H.1    Harley, J.B.2
  • 19
    • 0023663088 scopus 로고
    • A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen
    • Query, C. C , and J. D. Keene. 1987. A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell 51.211.
    • (1987) Cell , vol.51 , pp. 211
    • Query, C.C.1    Keene, J.D.2
  • 21
    • 0024509487 scopus 로고
    • Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MLR/lpr mice with lupus nephritis
    • Wuthrich, R P , M. A. Yui, G. Mazoujian, N Nabavi, L. H. Glimcher, and V. E Kelley. 1989. Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MLR/lpr mice with lupus nephritis. Am. J. Pathol. 134:45.
    • (1989) Am. J. Pathol. , vol.134 , pp. 45
    • Wuthrich, R.P.1    Yui, M.A.2    Mazoujian, G.3    Nabavi, N.4    Glimcher, L.H.5    Kelley, V.E.6
  • 23
    • 0025947390 scopus 로고
    • Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology
    • Harley, J. B , and R. H. Scofield. 1991. Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology J. Clin. Immunol. 11:297.
    • (1991) J. Clin. Immunol. , vol.11 , pp. 297
    • Harley, J.B.1    Scofield, R.H.2
  • 24
    • 0024382046 scopus 로고
    • Molecular basis of mitochondrial autoreactivity in primary biliary cirrhosis
    • Mackay, I R., and M. E. Gershwin. 1989. Molecular basis of mitochondrial autoreactivity in primary biliary cirrhosis. Immunol. Today 10.315.
    • (1989) Immunol. Today , vol.10 , pp. 315
    • Mackay, I.R.1    Gershwin, M.E.2
  • 25
    • 0027311314 scopus 로고
    • Reaction of anti-OJ autoantibodies to the multi-enzyme complex of aminoacyl-tRNA synthetases in addition to isoleucyl-tRNA synthetase
    • Targoff, I. N., E. P. Trieu, and F. W. Miller. 1993. Reaction of anti-OJ autoantibodies to the multi-enzyme complex of aminoacyl-tRNA synthetases in addition to isoleucyl-tRNA synthetase. J. Clin. Invest. 91.2556.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2556
    • Targoff, I.N.1    Trieu, E.P.2    Miller, F.W.3
  • 26
    • 0028912625 scopus 로고
    • Immunoglobulin epitope spreading and autoimmune disease after peptide immunization. Sm B/B′-derived PPPGMRPP and PPPGIRGP induce spiceosome autoimmunity
    • James, J. A., T. Gross, R. H. Scofield, and J B. Harley. 1995 Immunoglobulin epitope spreading and autoimmune disease after peptide immunization. Sm B/B′-derived PPPGMRPP and PPPGIRGP induce spiceosome autoimmunity J. Exp. Med. 181:453.
    • (1995) J. Exp. Med. , vol.181 , pp. 453
    • James, J.A.1    Gross, T.2    Scofield, R.H.3    Harley, J.B.4
  • 27
    • 0028809117 scopus 로고
    • Intra- and intermolecular spreading of autoimmunity involving the nuclear self antigens la (SS-B) and Ro (SS-A)
    • Topfer, F , T. Gordon, and J. McCluskey. 1995. Intra- and intermolecular spreading of autoimmunity involving the nuclear self antigens La (SS-B) and Ro (SS-A). Proc. Natl. Acad. Sci. USA 92:875.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 875
    • Topfer, F.1    Gordon, T.2    McCluskey, J.3
  • 29
    • 0024524337 scopus 로고
    • Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen
    • Ben-Chetrit, E , B. J. Gandy, E. M. Tan, and K. F. Sullivan 1989 Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen J. Clin. Invest. 83.1284.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1284
    • Ben-Chetrit, E.1    Gandy, B.J.2    Tan, E.M.3    Sullivan, K.F.4
  • 30
    • 0027400829 scopus 로고
    • Presence of anti-La(SS-B) is associated with binding to the 13-kD carboxyl terminus of 60-kD Ro(SS-A) in systemic lupus erythematosus
    • Dickey, W D., J E. van Egmond, K. L Hardgrave, J B. Harley, and R. H. Scofield. 1993. Presence of anti-La(SS-B) is associated with binding to the 13-kD carboxyl terminus of 60-kD Ro(SS-A) in systemic lupus erythematosus. J. Invest Dermatol 100:412.
    • (1993) J. Invest Dermatol , vol.100 , pp. 412
    • Dickey, W.D.1    Van Egmond, J.E.2    Hardgrave, K.L.3    Harley, J.B.4    Scofield, R.H.5
  • 31
    • 0027304779 scopus 로고
    • Xenopus Ro ribonucleoproteins: Members of an evolutionarily conserved class of cytoplasmic ribonucleoproteins
    • O'Brien, C. A., K. Margelot, and S L Wolin. 1993 Xenopus Ro ribonucleoproteins: members of an evolutionarily conserved class of cytoplasmic ribonucleoproteins. Proc. Natl. Acad. Sci. USA 90:7250.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7250
    • O'Brien, C.A.1    Margelot, K.2    Wolin, S.L.3
  • 32
    • 0028969186 scopus 로고
    • Human anti-Ro antibodies bind peptides accessible to the surface of the native Ro autoantigen
    • Huang, S.-C , H. Yu, R. H. Scofield, and J. B. Harley 1995 Human anti-Ro antibodies bind peptides accessible to the surface of the native Ro autoantigen. J Scand. Immunol 41:220.
    • (1995) J Scand. Immunol , vol.41 , pp. 220
    • Huang, S.-C.1    Yu, H.2    Scofield, R.H.3    Harley, J.B.4
  • 34
    • 0026056382 scopus 로고
    • A common epitope near the carboxyl terminus of the 60-kD Ro ribonucleoprotein: Sequence similarity with a viral protein
    • Scofield, R. H., W. D Dickey, K. W. Jackson, J. A. James, and J. B. Harley. 1991. A common epitope near the carboxyl terminus of the 60-kD Ro ribonucleoprotein: sequence similarity with a viral protein J Clin. Immunol 11:378.
    • (1991) J Clin. Immunol , vol.11 , pp. 378
    • Scofield, R.H.1    Dickey, W.D.2    Jackson, K.W.3    James, J.A.4    Harley, J.B.5
  • 35
    • 0001331728 scopus 로고
    • Synthetic pepnde vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system
    • Tarn, J. P. 1988. Synthetic pepnde vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. Proc. Natl. Acad. Sci. USA 85: 5409.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5409
    • Tarn, J.P.1
  • 36
    • 0021229129 scopus 로고
    • Molecular properties of the Ro (SS-A) antigen and the enzyme linked immunosorbent assay for quantification of antibody
    • Yamagata, H., J. B. Harley, and M. Reichlin. 1984. Molecular properties of the Ro (SS-A) antigen and the enzyme linked immunosorbent assay for quantification of antibody. J. Clin. Invest. 74:625.
    • (1984) J. Clin. Invest. , vol.74 , pp. 625
    • Yamagata, H.1    Harley, J.B.2    Reichlin, M.3
  • 38
    • 0029282723 scopus 로고
    • Immunization with vesicular stomatitis virus nucleocapsid protein induces autoantibodies to the 60 kDRo ribonucleoprotein particle
    • Huang, S.-C., Z. Pan, B. T. Kurien, J. A. James, J. B. Harley, and R. H Scofleld. 1995. Immunization with vesicular stomatitis virus nucleocapsid protein induces autoantibodies to the 60 kDRo ribonucleoprotein particle J. Invest. Med. 43:151.
    • (1995) J. Invest. Med. , vol.43 , pp. 151
    • Huang, S.-C.1    Pan, Z.2    Kurien, B.T.3    James, J.A.4    Harley, J.B.5    Scofleld, R.H.6
  • 39
    • 0025762393 scopus 로고
    • Induction of autoreactive B cells allows priming of autoreactive T cells
    • Lin, R. H., M. J. Mamula, I. A. Hardin, and C. A. Janeway, Jr 1991. Induction of autoreactive B cells allows priming of autoreactive T cells. J. Exp. Med. 173: 1433.
    • (1991) J. Exp. Med. , vol.173 , pp. 1433
    • Lin, R.H.1    Mamula, M.J.2    Hardin, I.A.3    Janeway Jr., C.A.4
  • 40
    • 0026750296 scopus 로고
    • Breaking tolerance with foreign and self co-immunogens: A study of B and T cell epitopes of cytochrome c
    • Mamula, M. J., R. H. Lin, C. A. Janeway, Jr., and J. A. Hardin. 1992. Breaking tolerance with foreign and self co-immunogens: a study of B and T cell epitopes of cytochrome c. J. Immunol. 149.789.
    • (1992) J. Immunol. , vol.149 , pp. 789
    • Mamula, M.J.1    Lin, R.H.2    Janeway Jr., C.A.3    Hardin, J.A.4
  • 41
    • 0027479452 scopus 로고
    • The inability to process a self-peptide allows autoreactive T cells to escape tolerance
    • Mamula, M. J. 1993. The inability to process a self-peptide allows autoreactive T cells to escape tolerance. J. Exp. Med. 177:567.
    • (1993) J. Exp. Med. , vol.177 , pp. 567
    • Mamula, M.J.1
  • 43
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinates of an autoantigen
    • Lehmann, P. V., T. Forsthuber, A. Miller, and E. E. Sercarz 1992. Spreading of T-cell autoimmunity to cryptic determinates of an autoantigen. Nature 358:155.
    • (1992) Nature , vol.358 , pp. 155
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 44
    • 0014137949 scopus 로고
    • The immune re-sponse to a hybrid protein molecule specificity of secondary stimulation and of tolerance induction
    • Rajewsky, K., E. Rottlander, G. Peltre, and B. Muller. 1967. The immune re-sponse to a hybrid protein molecule specificity of secondary stimulation and of tolerance induction. J. Exp. Med. 126:581.
    • (1967) J. Exp. Med. , vol.126 , pp. 581
    • Rajewsky, K.1    Rottlander, E.2    Peltre, G.3    Muller, B.4
  • 45
    • 0018745584 scopus 로고
    • T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin
    • Russell, S. M., and F. Y. Liew. 1979. T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin. Nature 280:147.
    • (1979) Nature , vol.280 , pp. 147
    • Russell, S.M.1    Liew, F.Y.2
  • 46
    • 0019133770 scopus 로고
    • Cell cooperation in antibody response to influenza virus. I Priming of helper T cells by internal components of virion
    • Russell, S. M., and F Y. Liew. 1980. Cell cooperation in antibody response to influenza virus. I Priming of helper T cells by internal components of virion. Eur J. Immunol. 10:791
    • (1980) Eur J. Immunol. , vol.10 , pp. 791
    • Russell, S.M.1    Liew, F.Y.2
  • 47
    • 0022504418 scopus 로고
    • Functional analysis of influenza-specific helper T cell clones in vivo: T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin
    • Scherle, P. A., and W. Gerhard. 1986. Functional analysis of influenza-specific helper T cell clones in vivo: T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. J. Exp. Med. 000:1114.
    • (1986) J. Exp. Med. , pp. 1114
    • Scherle, P.A.1    Gerhard, W.2
  • 48
    • 0023256269 scopus 로고
    • Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site
    • Milich, D. R., A. McLachlan, G. B. Thorton, and J. L. Hughes. 1987. Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site. Nature 329.547.
    • (1987) Nature , vol.329 , pp. 547
    • Milich, D.R.1    McLachlan, A.2    Thorton, G.B.3    Hughes, J.L.4
  • 50
    • 0024577759 scopus 로고
    • Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice
    • Lee, L. A., K. K. Gaither, S. N. Coulter, D. A. Noms, and J. B. Harley. 1989. Pattern of cutaneous immunoglobulin G deposition in subacute cutaneous lupus erythematosus is reproduced by infusing purified anti-Ro (SSA) autoantibodies into human skin-grafted mice. J. Clin. Invest. 83:1556
    • (1989) J. Clin. Invest. , vol.83 , pp. 1556
    • Lee, L.A.1    Gaither, K.K.2    Coulter, S.N.3    Noms, D.A.4    Harley, J.B.5
  • 51
    • 0022337806 scopus 로고
    • Ro/SSA antigen and antibody in a patient with congenital complete heart block
    • Harley, J B., J. L. Kaine, O. F. Fox, M. Reichlin, and B Graber 1985 Ro/SSA antigen and antibody in a patient with congenital complete heart block. Arthritis Rheum. 28:1321.
    • (1985) Arthritis Rheum. , vol.28 , pp. 1321
    • Harley, J.B.1    Kaine, J.L.2    Fox, O.F.3    Reichlin, M.4    Graber, B.5


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