Determination of a novel indolylpiperazine anti-migraine agent in rat, monkey, mouse and rabbit plasma by high-performance liquid chromatography with electrochemical detection

Journal of Chromatography B: Biomedical Applications

Volumn 678, Issue 2, 1996, Pages 269-277

  Marathe, Punit H ^a   Larkin, Kimberlee D ^a   Duncan, Glenn F ^a   Greene, Douglas S ^a   Barbhaiya, Rashmi H ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Indolylpiperazine

Indexed keywords

3 [3 [4 (5 METHOXY 4 PYRIMIDYL) 1 PYPERAZINYL]PHROPYL] N METHYL 1 H INDOLE 5 METHANESULFONAMIDE; ANTIMIGRAINE AGENT; AVITRIPTAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; ELECTROCHEMICAL DETECTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MONKEY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; RAT; TECHNIQUE;

EID: 0030005546     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4347(95)00514-5     Document Type: Article

References (5)

1. H.L. Wiener, G.P. Thlody and F.D. Yocca, FASEB J. Abstr., 9 (1995) A347.
2. N.S. Sarbin, J.A. Gylys, L.G. Iben, C.D. Mahle, D.G. Izzarelli, E.M. Parker, J.W. Noonan, A.D. Williams, D.W. Smith, E. Hamel and F.D. Yocca, FASEB J. Abstr., 9 (1995) A347.
3. I. Jane and A. McKinnon, J. Chromatogr., 323 (1985) 191.
4. P.D. Andrew, H.L. Birch and D.A. Phillpot, J. Pharm. Sci., 82 (1993) 73.
5. V.P. Shah, K.K. Midha, S. Dighe, I.J. McGilveray, J.P. Skelly, A. Yacobi, T. Layloff, C.T. Viswanathan, C.E. Cook and R.D. McDowall, Eur. J. Drug Metab. Pharmacokin., 16 (1991) 249.