Protective effects of buprenorphine against amplified cocaine and ethanol lethality in mice : Role of cocaethylene

Journal of Toxicological Sciences

Volumn 21, Issue 2, 1996, Pages 143-156

  Hayase, Tamaki ^a   Yamamoto, Yoshiko ^a   Yamamoto, Keiichi ^a  

^a KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Buprenorphine; Cocaethylene; Cocaine; Ethanol; Lethality Mixed opioid agonist antagonist

Indexed keywords

ANIMALIA;

ALCOHOL; BUPRENORPHINE; COCAINE; HOMOCOCAINE;

ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABUSE; MOUSE; NONHUMAN; OPIATE ADDICTION; RESPIRATORY TRACT DISEASE;

EID: 0030005430     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.21.2_143     Document Type: Article

References (34)

1. Boyer, C. S. and Petersen, D. R. (1992) : Enzymatic basis for the transesterification of cocaine in the presence of ethanol : evidence for the participation of microsomal carboxylesterases. J. Pharmacol. Exp. Ther., 260, 939-946.
2. Cowan, A., Doxey, J. C. and Harry, E. J. R. (1977) : The animal pharmacology of buprenorphine, an oripavine analgesic agent. Br. J. Pharmacol., 60, 547-554.
3. Dawid-Milner, M. S., Diaz-Calavia, E. J., Lara, J. P., Fernández del Moral, R. and Jiménez-Vargas, J. (1989) : Electroencephalographic study of naloxone effects in the recovery of an acute alcoholic intoxication. Rev. Esp. Fisiol., 45, 207-210.
4. Dean, R. A., Harper, E. T., Dumaual, N., Stoeckel, D. A. and Bosron, W. F. (1992) : Effects of ethanol on cocaine metabolism : formation of cocaethylene and norcocaethylene. Toxicol. Appl. Pharmacol., 117, 1-8.
5. Derlet, R. W., Albertson, T. E. and Rice, P. (1990) : The effect of SCH 23390 against toxic doses of cocaine, d-amphetamine and methamphetamine. Life Sci., 47, 821-827.
6. Garrett, E. R. and Chandran, V. R. (1990) : Pharmacokinetics of morphine and its surrogates X : analyses and pharmacokinetics of buprenorphine in dogs. Biopharm. Drug Dispos., 11, 311-350.
7. Hayase, T., Matsubayashi, K., Ojima, K., Matsumoto, H., Yamamoto, Y., Yamamoto, K., Abiru, H. and Fukui, Y. (1995) : Protective effects of buprenorphine and Ro 15-4513 against combined cocaine-ethanol lethality. Jpn. J. Alcohol & Drug Dependence, 30, 314-315. (in Japanese)
8. Hearn, W. L., Flynn, D. D., Hime, G. W., Rose, S., Cofino, J. C., Mantero-Atienza, E., Wetli, C. V. and Mash, D. C. (1991a) : Cocaethylene : a unique cocaine metabolite displays high affinity for the dopamine transporter. J. Neurochem., 56, 698-701.
9. Hearn, W. L., Rose, S., Wagner, J., Ciarleglio, A. and Mash, D. C. (1991b) : Cocaethylene is more potent than cocaine in mediating lethality. Pharmacol. Biochem. Behav., 39, 531-533.
10. Hime, G. W., Hearn, W. L., Rose, S. and Cofino, J. (1991) : Analysis of cocaine and cocaethylene in blood and tissues by GC-NPD and GC-ion trap mass spectrometry. J. Anal. Toxicol., 15, 241-245.
11. Hyytiä, P. (1993) : Involvement of μ-opioid receptors in alcohol drinking by alcohol-preferring AA rats. Pharmacol. Biochem. Behav., 45, 697-701.
12. Jatlow, P. and Nadim, H. (1990) : Determination of cocaine concentrations in plasma by high-performance liquid chromatography. Clin. Chem., 36, 1436-1439.
13. Jattow, P. I., Van Dyke, C., Barash, P. and Byck, R. (1978) : Measurement of benzoylecgonine and cocaine in urine, separation of various cocaine metabolites using reversed-phase high-performance liquid chromatography. J. Chromatogr., 152, 115-121.
14. Jentzen, J. (1993) : Medical complications of cocaine abuse. Am. J. Clin. Pathol., 100, 475-476.
15. Jerrells, T. R., Smith, W. and Eckardt, M. J. (1990) : Murine model of ethanol-induced immunosuppression. Alcohol Clin. Exp. Res., 14, 546-550.
16. Karch, S. B. (1991) : Introduction to the forensic pathology of cocaine. Am. J. Forensic Med. Pathol., 12, 126-131.
17. Karch, S. B. and Stephens, B. S. (1991) : When is cocaine the cause of death. Am. J. Forensic Med. Pathol., 12, 1-2.
18. Lewis, J. W. (1985) : Buprenorphine. Drug Alc. Depend., 14, 363-372.
19. Matsubara, K., Maseda, C. and Fukui, Y. (1984): Quantitation of cocaine, benzoylecgonine and ecgonine methyl ester by GC-CI-SIM after Extrelut extraction. Forensic Sci. Int., 26, 181-192.
20. Mello, N. K. and Mendelson, J. H. (1992) : Primate studies of the behavioral pharmacology of buprenorphine. NIDA Res. Monogr. Ser., 121, 61-100.
21. Mendelson, J. H. and Mello, N. K. (1992) : Human laboratory studies of buprenorphine. NIDA Res. Monogr. Ser., 121, 38-60.
22. Perez-Reyes, M. and Jeffcoat, A. R. (1992) : Ethanol/ cocaine interaction : cocaine and cocaethylene plasma concentrations and their relationship to subjective and cardiovascular effects. Life Sci., 51, 553-563.
23. Randall, T. (1992) : Cocaine, alcohol mix in body to form even longer lasting, more lethal drug. J. Am. Med. Assoc., 267, 1043-1044.
24. Roberts, S. M., Munson, J. W., James, R. C. and Harbison, R. D. (1992) : An assay for cocaethylene and other cocaine metabolites in liver using high-performance liquid chromatography. Anal. Biochem., 202, 256-261.
25. Roberts, S. M., Harbison, R. D. and James, R. C. (1993) : Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver. Drug Metab. Dispos., 21, 537-541.
26. Shukla, V. K., Goldfrank, L. R., Turndorf, H. and Bansinath, M. (1991) : Antagonism of acute cocaine toxicity by buprenorphine. Life Sci., 49, 1887-1893.
27. Tsibulsky, V. L. and Amit, Z. (1993) : Tolerance to effects of high doses of ethanol : 1. lethal effects in mice. Pharmacol. Biochem. Behav., 45, 465-472.
28. Tsunoda, T. and Teruya, K. (1990) : Epidemiological aspect of alcohol. J. Clin. Exp. Med., 150, 805-810. (in Japanese)
29. Villiger, J. W. and Taylor, K. M. (1981) : Buprenorphine : characteristics of binding sites in the rat central nervous system. Life Sci., 29, 2699-2708.
30. Wada, K. (1994) : Cocaine abuse in Japan. Jpn. J. Alcohol & Drug Dependence, 29, 83-91.
31. Welder, A. A., Dickson, L. J. and Melchert, R. B. (1993) : Cocaethylene toxicity in rat primary myocardial cell cultures. Alcohol, 10, 285-290.
32. Welder, A. A., Smith, M. A., Ramos, K. and Acosta, D. (1988) : Cocaine-induced cardiotoxicity in vitro. Toxic. in Vitro, 2, 205-213.
33. Witkin, J. M., Johnson, R. E., Jaffe, J. H., Goldberg, S. R., Grayson, N. A., Rice, K. C. and Katz, J. L. (1991) : The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine. Drug Alc. Depend., 27, 177-184.
34. I receptors in the lethal effects of cocaine and a quaternary methodide analog. J. Pharmacol. Exp. Ther., 267, 266-274.