Adenosine slows the rate of K+-induced membrane depolarization in ventricular cardiomyocytes: Possible implication in hyperkalemic cardioplegia

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 6, 1996, Pages 1193-1202

  Alekseev, Alexey E ^a   Jovanović, Aleksandar ^a   López, Jóse R ^a   Terzic, Andre ^a  

^a MAYO CLINIC   (United States)

Author keywords

Adenosine; Ca2+; Cardiomyocyte; Cardioplegia; Depolarization; K+

Indexed keywords

ADENOSINE; CALCIUM ION; CARDIOPLEGIC AGENT; POTASSIUM ION;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CARDIOPLEGIA; CONTROLLED STUDY; GUINEA PIG; HEART DISEASE; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE WALL; HYPERKALEMIA; MEMBRANE DEPOLARIZATION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; SODIUM CURRENT;

EID: 0030004698     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0110     Document Type: Article

References (34)

1. 2+ currents in isolated heart cells of hibernators. Biochem Mol Biol Int 33: 365-375.
2. BARRY WH, BRIDGE JHB, 1993. Intracellular calcium homeostasis in cardiac myocytes. Circulation 87: 1806-1815.
3. BELARDINELLI L, ISENBERG G, 1983. Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res 53: 287-297.
4. BELARDINELLI L, LINDEN J, BERNE RM, 1989. The cardiac effect of adenosine. Prog Cardiovasc Dis 32: 73-97.
5. BELARDINELLI L, SHRYOCK JC, SONG Y, WANG D, SRINIVAS M, 1995. Ionic basis of the electrophysiological actions of adenosine on cardiomyocytes. FASEB J9: 359-365.
6. BOEHM DH, HUMAN PA, VAN OPPELL U, OWEN P, REICHENSPURNER H, OPIE LH, ROSE AG, REICHART B, 1991. Adenosine cardioplegia: reducing reperfusion injury of the ischaemic myocardium? Eur J Cardio Thorac Surg 5: 542-545.
7. CLAPHAM DE, 1989. Potassium and tissue excitability. In: Seldin DW, Giebisch G, eds. The Regulations of Potassium Balance. Raven Press, New York, 57-87.
8. CRONSTEIN BN, 1994. Adenosine, an endogenous anti-inflammatory agent. J Appl Physiol 76: 5-13.
9. CYRAN SE, PHILIPS J, DITTY S, BAYLEN BG, CHEUNG J, LANOUE K, 1993. Developmental differences in cardiac myocyte calcium homeostasis after steady-state potassium depolarization: Mechanisms and implications for cardioplegia. J Pediatr 122: S77-S83.
10. DE JONG JW, DER MEER PV, LOON HV, OWEN P, OPIE LH, 1990. Adenosine as adjunct to potassium cardioplegia: effect of function, energy metabolism, and electrophysiology. J Thorac Cardiovasc Surg 100: 445-454.
11. ENGELMAN RM, LEVITSKY S, 1992. A Textbook for Cardioplegia for Difficult Clinical Problems. Futura Publishing Company, Inc., Mount Kisco, NY
12. FABIATO A, 1985. Simulated calcium current can both cause calcium loading in and trigger the calcium release from the sarcoplasmic reticulum of a skinned cardiac cell. J Gen Physiol 85: 291-320.
13. + channels in cardiac muscle by the sulphonylurea drug glibenclamide. J Pharmacol Exp Ther 261: 540-545.
14. GATELL JA, BARNER HB, SHEVDE K, 1993. Adenosine and myocardial protection. J Cardiothor Vasc Anest 7: 466-480.
15. + channel current in atrial myocytes of guinea pig heart. Jpn J Pharmacol 54: 473-477.
16. HEARSE DG, BRAIMBRIDGE MV, JYNGE P, 1981. Protection of the Ischemic Myocardium: Cardioplegia. Raven Press, NY.
17. HORN R, MARTY A, 1988. Mu scarinic activation of ionic current measured by a new whole cell recording method. J Gen Physiol 92: 145-159.
18. HUDSPETH DA, NAKANASHI K, VINTEN-JOHANSEN J, ZHAO ZQ, MCGEE S, WILLIAMS MW, HAMMON JW, 1994. Adenosine in blood cardioplegia prevents postischemic dysfunction in ischemically injured hearts. Ann Thorac Surg 58: 1637-1644.
19. KELLER MW, GEDDES L, SPOTNITZ W, DULING BR, 1991. Microcirculatory dysfunction following perfusion with hyperkalemic, hypothermic, cardioplegic solutions and blood reperfusion. Effect of adenosine. Circulation 84: 2485-2494.
20. + channels to A1 receptors by G proteins in rat ventricular myocytes. Am J Physiol 259: H820-H826.
21. KUSUOKA H, MARBAN E, 1993. Role of altered calcium homeostasis in stunned myocardium. In: KLONER RA, PRZYKLENK K, eds, Stunned Myocardium: Properties, Mechanisms, and Clinical Manifestations. New York, Marcel Dekker, 197-213.
22. 2+ waves: A laser confocal microscopy study. Am J Physiol, (in press).
23. LÓPEZ JR, JOVANOVIC A, TERZIC A, 1995. Spontaneous calcium waves without contraction in cardiac myocytes. Biochem Biophys Res Commun 214: 781-787.
24. POWELL T, TATHAM PER, TWIST VW, 1984. Cytoplasmic free calcium measured by QUIN2 fluorescence in isolated ventricular myocytes at rest and during potassium-depolarization. Biochem Biophys Res Commun 122: 1012-1020.
25. RAE J, COOPER K, GATES P, WATSKY M, 1991. Low access resistance perforated patch recordings using amphotericin B. J Neurosci Methods 37: 15-26.
26. SHEN WK, KURACHI Y, 1995. Mechanisms of adenosine-mediated actions on cellular and clinical cardiac electrophysiology. Mayo Clin Proc 70: 274-291.
27. THORNTON JD, LIU GS, OLSSON RA, DOWNEY JM, 1992. Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation 85: 659-665.
28. + channels: Regulation by intracellular nucleotides and potassium channel opening drugs. Am J Physiol 38: C525-C545.
29. + channels. J Pharmacol Exp Ther 268: 818-825.
30. + channels by antagonizing ATP-dependent gating. Neuron 12: 885-893.
31. TYTGAT J, VEERECKE J, CARMELIET E, 1990. A combined study of sodium current and T-type calcium current in isolated cardiac cells. Pflügers Arch 417: 142-148.
32. VINTEN-JOHANSEN J, NAKANISHI K, ZHAO ZQ, MCGEE DS, TAN P, 1993. Adenosine improves surgical myocardial protection with blood cardioplegia in ischemically injured canine heart. Circulation 88 [Suppl. 2]: 350-359.
33. VINTEN-JOHANSEN J, NAKANISHI K, 1993. Postcardioplegia acute cardiac dysfunction and reperfusion injury. J Cardiothor Vasc Anest 7: 6-18.
34. YAO Z, GROSS GJ, 1993. Glibenclamide antagonizes adenosine A1 receptor-mediated cardioprotection in stunned myocardium. Circulation 88: 235-244.