Comparative effects of dietary nucleoside-nucleotide mixture and its components on endotoxin induced bacterial translocation and small intestinal injury in protein deficient mice

Gut

Volumn 38, Issue 4, 1996, Pages 531-537

  Adjei, A A ^a   Yamauchi, K ^a   Chan, Y C ^a   Konishi, M ^a   Yamamoto, S ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Bacterial translocation; Endotoxin; Nucleosides; Nucleotides; Protein deficiency

Indexed keywords

CYTIDINE; ENDOTOXIN; GUANOSINE PHOSPHATE; LIPOPOLYSACCHARIDE; NUCLEOSIDE; NUCLEOTIDE; THYMIDINE; URIDINE;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL METABOLISM; DIET; HISTOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SMALL INTESTINE DISEASE;

EID: 0030004475     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.38.4.531     Document Type: Article

References (35)

1. Saadia R, Schein M, MacFarlane C, Boffard KD. Gut barrier function and the surgeon. Br J Surg 1990; 77: 487-92.
2. Willmore DW, Smith RJ, O'Dwyer ST, Jacobs DO, Ziegler TR, Wang XD. The gut: a central organ after surgical stress. Surgery 1988; 104: 917-23.
3. Sori A, Rush BF, Lysz TW, Smith S, Machiedo GW. The gut as a source of sepsis following haemorphagic shock. Am J Surg 1988; 155: 187-91.
4. Cameo J, Meakin JL. Multiple organ failure syndrome. Arch Surg 1986; 121: 99-103.
5. Shiner M, Nichols VN, Barrish JF, Nichols BL. Pathogenesis of small-intestinal mucosal lessions in chronic diarrhea of infancy: II. An electron microscopic study. J Pediatr Gastroenterol Nutr 1990; 11: 464-80.
6. Gyorgy P. Biochemical aspects of human milk. Am J Clin Nutr 1971; 24: 970-5.
7. Tanaka R, Mutai M. Improved medium for selective isolation and enumeration of bifidobacterium. Appl Environ Microbiol 1980; 40: 866-9.
8. Gil A, Coval E, Martinez A, Molina JA. Effects of dietary nucleotides on the microbial pattern of feces at term infants. J Clin Nutr Gastroenterol 1986; 1: 34-8.
9. Iijima S, Tsujinaka T, Kido Y, Hayashida Y, Ishida H, Homma T, et al. Intravenous administration of nucleosides and a nucleotide mixture diminishes intestinal mucosal atrophy induced by total parenteral nutrition. JPEN J Parenter Enteral Nutr 1993; 17: 265-70.
10. Uauy R, Stringel G, Thomas R, Quan R. Effect of a dietary nucleosides on growth and maturation of the development of the gut in the rat. J Pediatr Gastroenterol Nutr 1990; 10: 497-503.
11. Nunez MC, Ayudarte MV, Morales M, Suarez MD, Gil A. Effect of dietary nucleotides on intestinal repair in rats with experimental chronic diarrhoea. JPEN J Parenter Enteral Nutr 1990; 14: 598-604.
12. Brunser O, Espinoza J, Araya M, Cruchet S, Gil A. Effect of dietary nucleotide supplementation of diarrhoeal disease in infants. Acta Paediatrica 1994; 83: 188-91.
13. Grimble GK. Dietary nucleotides and gut mucosal defence. Gut 1994; 35 (suppl 1): S46-51.
14. Bueno J, Torres M, Almendros A, Carmona R, Nunez MC, Gil A. Effect of dietary nucleotides on small intestinal repair after diarrhoea. Histological and ultrastructural changes. Gut 1994; 35: 926-33.
15. Kulkarni AD, Rudolph FB, Van Buren CT. The role of dietary sources of nucleotides in immune function: a review. J Nutr 1994; 124: 1442-6S.
16. Rudolph FB, Kulkarni AD, Fanslow WC, Pizzini RP, Van Buren CT. Role of RNA as a dietary source of pyrimidines and purines in immune function. Nutrition 1990; 6: 45-52.
17. Adjei AA, Ohshiro Y, Yamauchi K, Nakasone Y, Shimada K, Iwanaga M, et al. Intraperitoneal administration of nucleoside-nucleotide mixture inhibits endotoxin-induced bacterial translocation in protein-deficient mice. Tohoku J Exp Med 1994; 174: 1-10.
18. Adjei AA, Yamamoto S. A dietary nucleoside-nucleotide mixture inhibits endotoxin-induced bacterial translocation in mice led protein-deficient diet. J Nutr 1995; 125: 42-8.
19. Daly JM, Liberman MD, Goldfine J, Shou J, Weintraub F, Rosato EF, et al. Enteral nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: immunologic, metabolic, and clinical outcomes. Surgery 1992; 112: 56-60.
20. Savaiano DA, Ho CY, Chu V. Metabolism of orally and intravenously administered purines in rats. J Nutr 1980; 110: 1793-804.
21. Ho CY, Miller KV, Savaiano DA. Absorption and metabolism of orally administered purines in fed and fasted rats, J Nutr 1979; 109: 1377-82.
22. Sonoda T, Tatibana M. Metabolic fate of pyrimidines and purines in dietary nucleic acids ingested by mice. Biochem Biophys Acta 1978; 521: 55-56.
23. Garre MA, Boles JM, Youinou PY. Current concepts in immune derangement due to undernutrition. JPEN J Parenter Enteral Nutr 1987; 11: 309-14.
24. Deitch EA, Berg RD. Endotoxin but not malnutrition promotes bacterial translocation of the gut flora in burned mice. J Trauma 1987; 27: 161-6.
25. Ogoshi S, Iwasa M, Kitagawa S. Effect of total parenteral nutrition with nucleoside-nucleotide mixture on D-galactosamine induced liver injury in rats. JPEN J Parenter Enteral Nutr 1988; 12: 53-8.
26. LeLeiko NS, Martin BA, Walsh M, Kazlow P, Rabinowitz S, Sterling K. Tissue-specific gene expression results from a purine and pyrimidine-free diet and 6-mercaptopurine in the rat small intestine and colon. Gastroenterology 1987; 93: 1014-20.
27. Souba WW, Wilmore DW. Postoperative alteration of arteriovenous exchange of amino acids cross the gastrointestinal tract. Surgery 1983; 94: 342-50.
28. Savaiano DA, Clifford AJ. Absorption, tissue incorporation and excretion of free-purine bases in rat. Nutrition Reports International 1978; 17: 551-6.
29. Savaiano DA, Clifford AJ. Adenine, the precursor of nucleic acids in intestinal cells unable to synthesize purines de novo. J Nutr 1981; 111: 1816-22.
30. Bendich A, Getler H, Brown GB. Studies in metabolism of purines and pyrimidines by isotopic nitrogen. J Biol Chem 1949; 177: 565-70.
31. Plentl AA, Schoenheimer R. Synthesis of isotope cytosine and study of its metabolism in rats. J Biol Chem 1944; 153: 203-17.
32. Burridge PW, Woods RA, Henderson JF. Utilization of dietary nucleic acid purines for nucleotide and nucleic acid synthesis in the mouse. Can J Biochem 1976; 54: 500-6.
33. Wilson DW, Wilson HC. Studies on in vitro digestion and absorption of purine ribonucleotides by the intestine. J Biol Chem 1962; 237: 1643-7.
34. Ogoshi S, Iwasa M, Yonezawa T, Tamiya T. Effect of nucleoside and nucleotide mixture on rats given total parenteral nutrition after 70% hepatectomy. JPEN J Parenter Enteral Nutr 1985; 9: 339-42.
35. Ogoshi S, Iwasa M, Mizobuchi S. Effect of a nucleoside-nucleotide mixture on protein metabolism in rats given total parenteral nutrition after 70% hepatectomy. In: Tanaka T, Okada A, eds. Nutritional support in organ failure. Amsterdam: Elsevier, 1988: 309-17.