메뉴 건너뛰기




Volumn 92, Issue 2, 1996, Pages 138-149

Nuclear and mitochondrial changes of co-cultivated spinal cord, spinal ganglia and muscle fibers following treatment with various doses of zidovudiue

Author keywords

AIDS; Mitochondria; Myopathy; Nucleus; Zidovudine

Indexed keywords

ZIDOVUDINE;

EID: 0030004222     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050501     Document Type: Article
Times cited : (17)

References (72)
  • 4
    • 0026028226 scopus 로고
    • Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy
    • Arnaudo E, Dalakas M, Shanske S, Moraes CT, DiMauro S, Schon EA (1991) Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet 337: 508-510
    • (1991) Lancet , vol.337 , pp. 508-510
    • Arnaudo, E.1    Dalakas, M.2    Shanske, S.3    Moraes, C.T.4    DiMauro, S.5    Schon, E.A.6
  • 5
    • 0024353605 scopus 로고
    • Biochemical pharmacology of zidovudine in human T-lymphoblastoid cell (CEM)
    • Avramis VI, Markson W, Jackson RL, Gomperts E (1989) Biochemical pharmacology of zidovudine in human T-lymphoblastoid cell (CEM). AIDS 3: 417-422
    • (1989) AIDS , vol.3 , pp. 417-422
    • Avramis, V.I.1    Markson, W.2    Jackson, R.L.3    Gomperts, E.4
  • 6
    • 0023868605 scopus 로고
    • The in vitro and in vivo antiretrovirus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxycytidine are highly dependent on the cell species
    • Balzarini J, Pauwels R, Baba M, Herdewijn P, De Clerko E, Broder S, Johns DG (1988) The in vitro and in vivo antiretrovirus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxycytidine are highly dependent on the cell species, Biochem Pharmacol 37: 897-903
    • (1988) Biochem Pharmacol , vol.37 , pp. 897-903
    • Balzarini, J.1    Pauwels, R.2    Baba, M.3    Herdewijn, P.4    De Clerko, E.5    Broder, S.6    Johns, D.G.7
  • 8
    • 0023857703 scopus 로고
    • Severe polymyositis-like syndrome associated with zidovudine therapy of AIDS and ARC
    • Bessen LJ, Greene JB, Louie E, Seitzman P, Weinberg H (1988) Severe polymyositis-like syndrome associated with zidovudine therapy of AIDS and ARC. N Engl J Med 318: 708
    • (1988) N Engl J Med , vol.318 , pp. 708
    • Bessen, L.J.1    Greene, J.B.2    Louie, E.3    Seitzman, P.4    Weinberg, H.5
  • 9
    • 0024496974 scopus 로고
    • The effect of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) in 3′-azido-3′-deoxythymidine (AZT)-mediated biochemical and cytotoxic effects on normal human myeloid progenitor cells
    • Bhalla K, Birkhofer M, Grant S, Graham G (1989) The effect of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) in 3′-azido-3′-deoxythymidine (AZT)-mediated biochemical and cytotoxic effects on normal human myeloid progenitor cells. Exp Hematol 17: 17-20
    • (1989) Exp Hematol , vol.17 , pp. 17-20
    • Bhalla, K.1    Birkhofer, M.2    Grant, S.3    Graham, G.4
  • 10
    • 0017378110 scopus 로고
    • DNA polymerase of mitochondria is a gamma-polymerase
    • Bolden A, Noy GP, Weissbach A (1977) DNA polymerase of mitochondria is a gamma-polymerase. J Biol Chem 252: 3352-3356
    • (1977) J Biol Chem , vol.252 , pp. 3352-3356
    • Bolden, A.1    Noy, G.P.2    Weissbach, A.3
  • 11
    • 0016680565 scopus 로고
    • DNA chain termination by 2′,3′-dideoxythymidine in replicating mammalian cells
    • Byars N, Kidson C (1975) DNA chain termination by 2′,3′-dideoxythymidine in replicating mammalian cells. Biochemistry 14: 3159-3164
    • (1975) Biochemistry , vol.14 , pp. 3159-3164
    • Byars, N.1    Kidson, C.2
  • 12
    • 0028017343 scopus 로고
    • Expression of cytochrome c oxidase subunits encoded by mitochondrial or nuclear DNA in the muscle of patients with zidovudine myopathy
    • Chariot P, Bonne G, Authier F-J, Marsac C, Gherardi R (1994) Expression of cytochrome c oxidase subunits encoded by mitochondrial or nuclear DNA in the muscle of patients with zidovudine myopathy. J Neurosci 125: 190-193
    • (1994) J Neurosci , vol.125 , pp. 190-193
    • Chariot, P.1    Bonne, G.2    Authier, F.-J.3    Marsac, C.4    Gherardi, R.5
  • 14
    • 0026663022 scopus 로고
    • Correlation of neuromuscular pathology in acquired immune deficiency syndrome patients with cytomegalovirus infection and zidovudine treatment
    • Cornford ME, Ho HW, Vinters HV (1992) Correlation of neuromuscular pathology in acquired immune deficiency syndrome patients with cytomegalovirus infection and zidovudine treatment. Acta Neuropathol 84: 516-529
    • (1992) Acta Neuropathol , vol.84 , pp. 516-529
    • Cornford, M.E.1    Ho, H.W.2    Vinters, H.V.3
  • 15
    • 0029069122 scopus 로고
    • Early features of zidovudine-associated myopathy: Histopathological findings and clinical correlations
    • Cupler EJ, Danon MJ, Jay C, Hench K, Ropka M, Dalakas MC (1995) Early features of zidovudine-associated myopathy: histopathological findings and clinical correlations. Acta Neuropathol 90: 1-6
    • (1995) Acta Neuropathol , vol.90 , pp. 1-6
    • Cupler, E.J.1    Danon, M.J.2    Jay, C.3    Hench, K.4    Ropka, M.5    Dalakas, M.C.6
  • 16
    • 0023806009 scopus 로고
    • Neuromuscular diseases associated with human immunodeficiency virus infection
    • Dalakas MC, Pezeshkpour GH (1988) Neuromuscular diseases associated with human immunodeficiency virus infection. Ann Neurol 23 [Suppl]: S38-S48
    • (1988) Ann Neurol , vol.23 , Issue.SUPPL.
    • Dalakas, M.C.1    Pezeshkpour, G.H.2
  • 19
    • 0028047177 scopus 로고
    • Schwann cell mitochondrial alterations in peripheral nerves of rabbits treated with 2′,3′-dideoxycytidine
    • Feldman D, Anderson TD (1994) Schwann cell mitochondrial alterations in peripheral nerves of rabbits treated with 2′,3′-dideoxycytidine. Acta Neuropathol 87: 71-80
    • (1994) Acta Neuropathol , vol.87 , pp. 71-80
    • Feldman, D.1    Anderson, T.D.2
  • 20
    • 0026533958 scopus 로고
    • Ultrastructure of peripheral neuropathy induced in rabbits by 2′,3′-dideoxycytidine
    • Feldman D, Brosnan C, Anderson TD (1992) Ultrastructure of peripheral neuropathy induced in rabbits by 2′,3′-dideoxycytidine. Lab Invest 66: 75-85
    • (1992) Lab Invest , vol.66 , pp. 75-85
    • Feldman, D.1    Brosnan, C.2    Anderson, T.D.3
  • 26
    • 0028079797 scopus 로고
    • Cytokine expression in the muscle of HIV-infected patients: Evidence of interleukin-1 accumulation in mitochondria of AZT fibers
    • Gherardi RK, Florea-Strat A, Fromont G, Poron F, Sabourin J-C, Autier J (1994) Cytokine expression in the muscle of HIV-infected patients: evidence of interleukin-1 accumulation in mitochondria of AZT fibers. Ann Neurol 36: 752-758
    • (1994) Ann Neurol , vol.36 , pp. 752-758
    • Gherardi, R.K.1    Florea-Strat, A.2    Fromont, G.3    Poron, F.4    Sabourin, J.-C.5    Autier, J.6
  • 27
    • 0023939473 scopus 로고
    • Necrotizing myopathy and zidovudine
    • Gorard DA, Henry K, Giloff RJ (1988) Necrotizing myopathy and zidovudine. Lancet I: 1050
    • (1988) Lancet , vol.1 , pp. 1050
    • Gorard, D.A.1    Henry, K.2    Giloff, R.J.3
  • 28
    • 0022994602 scopus 로고
    • Azidothymidine neurotoxicity
    • Hagler DN, Frame PT (1986) Azidothymidine neurotoxicity (letter). Lancet II: 1392-1393
    • (1986) Lancet , vol.2 , pp. 1392-1393
    • Hagler, D.N.1    Frame, P.T.2
  • 30
    • 0026721244 scopus 로고
    • Major growth reduction and minor decrease in mitochondrial enzyme activity in cultured human muscle cells after exposure to zidovudine
    • Herzberg N, Zorn I, Zwart R, Portegies P, Bolhuis P (1992) Major growth reduction and minor decrease in mitochondrial enzyme activity in cultured human muscle cells after exposure to zidovudine. Muscle Nerve 15: 706-710
    • (1992) Muscle Nerve , vol.15 , pp. 706-710
    • Herzberg, N.1    Zorn, I.2    Zwart, R.3    Portegies, P.4    Bolhuis, P.5
  • 31
    • 0025339708 scopus 로고
    • Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases
    • Huang P, Farquhar D, Plunkett W (1990) Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases. J Biol Chem 265: 11914-11918
    • (1990) J Biol Chem , vol.265 , pp. 11914-11918
    • Huang, P.1    Farquhar, D.2    Plunkett, W.3
  • 32
    • 0014053552 scopus 로고
    • Segregation of nucleolar components in mycoplasma-infected cells
    • Jézéquel AM, Shreeve MM, Steiner JW (1967) Segregation of nucleolar components in mycoplasma-infected cells. Lab Invest 16: 287-304
    • (1967) Lab Invest , vol.16 , pp. 287-304
    • Jézéquel, A.M.1    Shreeve, M.M.2    Steiner, J.W.3
  • 34
    • 0026356201 scopus 로고
    • Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model
    • Lamperth L, Dalakas MC, Dagani F, Anderson J, Ferrari R (1991) Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model. Lab Invest 65: 742-751
    • (1991) Lab Invest , vol.65 , pp. 742-751
    • Lamperth, L.1    Dalakas, M.C.2    Dagani, F.3    Anderson, J.4    Ferrari, R.5
  • 35
    • 0027504238 scopus 로고
    • Myopathy in HIV infection: The role of zidovudine and the significance of tubuloreticular inclusions
    • Lane RJM, McLean KA, Moss J, Woodrow DF (1993) Myopathy in HIV infection: the role of zidovudine and the significance of tubuloreticular inclusions. Neuropathol Appl Neurobiol 19:406-413
    • (1993) Neuropathol Appl Neurobiol , vol.19 , pp. 406-413
    • Lane, R.J.M.1    McLean, K.A.2    Moss, J.3    Woodrow, D.F.4
  • 37
    • 0026681374 scopus 로고
    • Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria
    • Lewis W, Gonzalez B, Chomyn A, Papoian T (1992) Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria. J Clin Invest 89: 1354-1360
    • (1992) J Clin Invest , vol.89 , pp. 1354-1360
    • Lewis, W.1    Gonzalez, B.2    Chomyn, A.3    Papoian, T.4
  • 39
    • 0023618218 scopus 로고
    • Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5′-triphosphate in comparison to cellular polymerases alpha and beta
    • Matthes E, Lehman C, Scholz D, Janta-Lipinski M von, Gaertner K, Rosenthal HA, Langen P (1987) Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5′-triphosphate in comparison to cellular polymerases alpha and beta. Biochem Biophys Res Commun 148: 78-85
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 78-85
    • Matthes, E.1    Lehman, C.2    Scholz, D.3    Von Janta-Lipinski, M.4    Gaertner, K.5    Rosenthal, H.A.6    Langen, P.7
  • 43
    • 0024203302 scopus 로고
    • Azidothymidine inhibits mitogen stimulated growth and DNA-repair in human peripheral lymphocytes
    • Munch-Petersen B (1988) Azidothymidine inhibits mitogen stimulated growth and DNA-repair in human peripheral lymphocytes. Biochem Biophys Res Commun 157: 1369-1375
    • (1988) Biochem Biophys Res Commun , vol.157 , pp. 1369-1375
    • Munch-Petersen, B.1
  • 46
    • 0026078484 scopus 로고
    • Mechanism of inhibition of human immunodeficiency virus type I reverse transcriptase and human DNA-polymerases alpha, beta and gamma by the 5′-triphosphates of carbovir, 3′-azido-3′-deoxythymidine. 2′,3′-dideoxyguanosine. and 3′-deoxythymidine
    • Parker WB, White EL, Shaddix SC, Ross LJ, Buckheit RW, Germany JM, Secrist JA, Vince R, Shannon WM (1991) Mechanism of inhibition of human immunodeficiency virus type I reverse transcriptase and human DNA-polymerases alpha, beta and gamma by the 5′-triphosphates of carbovir, 3′-azido-3′-deoxythymidine. 2′,3′-dideoxyguanosine. and 3′-deoxythymidine. J Biol Chem 266: 1754-1762
    • (1991) J Biol Chem , vol.266 , pp. 1754-1762
    • Parker, W.B.1    White, E.L.2    Shaddix, S.C.3    Ross, L.J.4    Buckheit, R.W.5    Germany, J.M.6    Secrist, J.A.7    Vince, R.8    Shannon, W.M.9
  • 47
    • 0021237243 scopus 로고
    • Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and preAIDS
    • Popovic M, Sarnpadharan MG, Read E, Gallo RC (1984) Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and preAIDS. Science 224: 497-500
    • (1984) Science , vol.224 , pp. 497-500
    • Popovic, M.1    Sarnpadharan, M.G.2    Read, E.3    Gallo, R.C.4
  • 48
    • 0014303148 scopus 로고
    • The relationship of nucleolar segregation to ribonucleic acid synthesis following the administration of selected hepatocarcinogens
    • Reddy J, Svoboda D (1968) The relationship of nucleolar segregation to ribonucleic acid synthesis following the administration of selected hepatocarcinogens. Lab Invest 19: 132-145
    • (1968) Lab Invest , vol.19 , pp. 132-145
    • Reddy, J.1    Svoboda, D.2
  • 50
    • 0024843942 scopus 로고
    • Overexpression of DNA replication and repair enzymes in cisplatin-resistant human colon carcinoma HCT8 cells and circumvention by azidothymidine
    • Scanlon KJ, Kashani-Sabet M, Sowers LC (1989) Overexpression of DNA replication and repair enzymes in cisplatin-resistant human colon carcinoma HCT8 cells and circumvention by azidothymidine. Cancer Commun 1: 269-275
    • (1989) Cancer Commun , vol.1 , pp. 269-275
    • Scanlon, K.J.1    Kashani-Sabet, M.2    Sowers, L.C.3
  • 51
    • 0141975151 scopus 로고
    • Pathologie der Muskulatur
    • Doerr J, Seifert G, Uehlinger E (eds) Springer, Berlin Heidelberg New York
    • Schröder JM (1982) Pathologie der Muskulatur. In: Doerr J, Seifert G, Uehlinger E (eds) Spezielle pathologische Anatomie, vol 15. Springer, Berlin Heidelberg New York, pp 444-454
    • (1982) Spezielle Pathologische Anatomie , vol.15 , pp. 444-454
    • Schröder, J.M.1
  • 52
    • 0026475810 scopus 로고
    • Nuclear and mitochondrial changes of muscle fibers in AIDS after treatment with high doses of zidovudine
    • Schröder JM, Bertram M, Schnabel R, Pfaff U (1992) Nuclear and mitochondrial changes of muscle fibers in AIDS after treatment with high doses of zidovudine. Acta Neuropathol 85: 39-47
    • (1992) Acta Neuropathol , vol.85 , pp. 39-47
    • Schröder, J.M.1    Bertram, M.2    Schnabel, R.3    Pfaff, U.4
  • 53
    • 0018792497 scopus 로고
    • A phylogenetic study on vertebrate mitochondrial DNA polymerase
    • Scovassi AI, Wicker R, Bertazzoni U (1979) A phylogenetic study on vertebrate mitochondrial DNA polymerase. Eur J Biochem 100: 491-496
    • (1979) Eur J Biochem , vol.100 , pp. 491-496
    • Scovassi, A.I.1    Wicker, R.2    Bertazzoni, U.3
  • 55
    • 0026656346 scopus 로고
    • Peripheral neuropathies associated with human immunodeficiency virus infection
    • Simpson DM, Olney RK (1992) Peripheral neuropathies associated with human immunodeficiency virus infection. Neurol Clin 10: 685-711
    • (1992) Neurol Clin , vol.10 , pp. 685-711
    • Simpson, D.M.1    Olney, R.K.2
  • 56
    • 0024521381 scopus 로고
    • Studies on the inhibition of mitochondrial DNA-replication by 3′-azido-3′-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-I replication
    • Simpson MV, Chin CD, Keilbaugh SA, Lin T-S, Prusoff WH (1989) Studies on the inhibition of mitochondrial DNA-replication by 3′-azido-3′-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-I replication. Biochem Pharmacol 38: 1033-1036
    • (1989) Biochem Pharmacol , vol.38 , pp. 1033-1036
    • Simpson, M.V.1    Chin, C.D.2    Keilbaugh, S.A.3    Lin, T.-S.4    Prusoff, W.H.5
  • 57
    • 8944259209 scopus 로고
    • Oncolysis by herpes simplex
    • Sistori C, Bosisio M (1966) Oncolysis by herpes simplex. Lancet I: 96
    • (1966) Lancet , vol.1 , pp. 96
    • Sistori, C.1    Bosisio, M.2
  • 59
    • 0023113366 scopus 로고
    • Toxicity of 3′-azido-3′-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro
    • Sommadossi J-P, Carlisle R (1987) Toxicity of 3′-azido-3′-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro. Antimicrob Agents Chemother 31: 452-454
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 452-454
    • Sommadossi, J.-P.1    Carlisle, R.2
  • 60
    • 0024353932 scopus 로고
    • Cellular pharmacology of 3′-azido-3′-deoxythymidine with evidence of incorporation into DNA of human bone marrow cells
    • Sommadossi J-P, Carlisle R, Zhou Z (1989) Cellular pharmacology of 3′-azido-3′-deoxythymidine with evidence of incorporation into DNA of human bone marrow cells. Mol Pharmacol 36: 9-14
    • (1989) Mol Pharmacol , vol.36 , pp. 9-14
    • Sommadossi, J.-P.1    Carlisle, R.2    Zhou, Z.3
  • 62
    • 0023140091 scopus 로고
    • Myopathy complicating the acquired immune deficiency syndrome
    • Stern R, Gold J, DiCarlo EF (1987) Myopathy complicating the acquired immune deficiency syndrome. Muscle Nerve 10: 318-322
    • (1987) Muscle Nerve , vol.10 , pp. 318-322
    • Stern, R.1    Gold, J.2    DiCarlo, E.F.3
  • 63
    • 0013978406 scopus 로고
    • Electron microscopic observations of herpes virus hominis (herpes simplex virus) encephalitis in man
    • Swanson JL, Craighead JE, Reynolds ES (1966) Electron microscopic observations of herpes virus hominis (herpes simplex virus) encephalitis in man. Lab Invest 15: 1966-1981
    • (1966) Lab Invest , vol.15 , pp. 1966-1981
    • Swanson, J.L.1    Craighead, J.E.2    Reynolds, E.S.3
  • 64
    • 0025165388 scopus 로고
    • Myopathy with human immunodeficiency virus type I (HIV-1) infection: HIV-1 or zidovudine?
    • Till M, MacDonell KB (1990) Myopathy with human immunodeficiency virus type I (HIV-1) infection: HIV-1 or zidovudine? Ann Intern Med 113: 492-494
    • (1990) Ann Intern Med , vol.113 , pp. 492-494
    • Till, M.1    MacDonell, K.B.2
  • 65
    • 0015385845 scopus 로고
    • The effects of cadmium chloride on organotypic cultures of rat sensory ganglia. A light and electron microscopic study
    • Tischner KH, Schröder JM (1972) The effects of cadmium chloride on organotypic cultures of rat sensory ganglia. A light and electron microscopic study. J Neurol Sci 16: 383-399
    • (1972) J Neurol Sci , vol.16 , pp. 383-399
    • Tischner, K.H.1    Schröder, J.M.2
  • 66
    • 0021133526 scopus 로고
    • Effect of 5-fluoro-2′-deoxyuridine and hydroxyurea on the phytohemagglutinin-induced increase of thymidine kinase, replicative DNA polymerase, deoxycytidylate deaminase, and CDP reductase activity in human lymphocytes
    • Tyrsted G (1984) Effect of 5-fluoro-2′-deoxyuridine and hydroxyurea on the phytohemagglutinin-induced increase of thymidine kinase, replicative DNA polymerase, deoxycytidylate deaminase, and CDP reductase activity in human lymphocytes. Mol Cell Biochem 62: 165-174
    • (1984) Mol Cell Biochem , vol.62 , pp. 165-174
    • Tyrsted, G.1
  • 67
    • 0025694701 scopus 로고
    • 3′-Azido-3′-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-962 human leukemia cells
    • Weidner DA, Sommadossi J-P (1990) 3′-Azido-3′-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-962 human leukemia cells. Mol Pharmacol 38: 797-804
    • (1990) Mol Pharmacol , vol.38 , pp. 797-804
    • Weidner, D.A.1    Sommadossi, J.-P.2
  • 68
    • 0015295896 scopus 로고
    • Comparison of the effects of Coxsackie virus A9 and of actinomycin D on the nucleolar ultrastructure of the monkey kidney cells
    • Weiss M, Meyer J (1972) Comparison of the effects of Coxsackie virus A9 and of actinomycin D on the nucleolar ultrastructure of the monkey kidney cells. J Ultrastruct Res 38: 411-419
    • (1972) J Ultrastruct Res , vol.38 , pp. 411-419
    • Weiss, M.1    Meyer, J.2
  • 69
    • 0024510485 scopus 로고
    • HTLV-I myositis in a patient also infected with the human immunodeficiency virus
    • Wiley CA, Nerenberg M, Cros D, Soto-Aguilar MC (1989) HTLV-I myositis in a patient also infected with the human immunodeficiency virus. N Engl J Med 320: 992-995
    • (1989) N Engl J Med , vol.320 , pp. 992-995
    • Wiley, C.A.1    Nerenberg, M.2    Cros, D.3    Soto-Aguilar, M.C.4
  • 71
    • 0025035475 scopus 로고
    • Reversal of azidothymidine-induced bone-marrow suppression by 2′,3′-dideoxythymidine as studied by hematopoietic clonal culture
    • Yoshida Y, Yoshida C (1990) Reversal of azidothymidine-induced bone-marrow suppression by 2′,3′-dideoxythymidine as studied by hematopoietic clonal culture. AIDS Res Hum Retroviruses 6: 929-932
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 929-932
    • Yoshida, Y.1    Yoshida, C.2
  • 72
    • 8944224301 scopus 로고
    • Studies on mechanism of toxicity of 3′-azido-3′-deoxythymidine (AZT) in human bone marrow (HBM) cells
    • Zhu Z, Carlisle R, Sommadossi J-P (1988) Studies on mechanism of toxicity of 3′-azido-3′-deoxythymidine (AZT) in human bone marrow (HBM) cells, Intersci Conf Antimicrob Agents Chemother 28: 1466
    • (1988) Intersci Conf Antimicrob Agents Chemother , vol.28 , pp. 1466
    • Zhu, Z.1    Carlisle, R.2    Sommadossi, J.-P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.