Combination of ondansetron and dexamethasone in the prophylaxis of postoperative nausea and vomiting

British Journal of Anaesthesia

Volumn 76, Issue 6, 1996, Pages 835-840

  Lopez Olaondo L ^a,b   Carrascosa, F ^a   Pueyo, F J ^a   Monedero, P ^a   Busto, N ^a   Saez A ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b Universitaria de Navarra   (Spain)

Author keywords

Pharmacology, dexamethasone; Pharmacology, ondansetron; Surgery, gynaecological; Vomiting, antimetics; Vomiting, nausea

Indexed keywords

DEXAMETHASONE; MORPHINE; ONDANSETRON; PLACEBO; SODIUM CHLORIDE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MIXTURE; DRUG SAFETY; FEMALE; GENERAL ANESTHESIA; HEADACHE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; NAUSEA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROPHYLAXIS; PROSPECTIVE STUDY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; VOMITING;

EID: 0030004187     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/76.6.835     Document Type: Article

References (28)

1. Watcha MF, White PF. Postoperative nausea and vomiting: its etiology, treatment and prevention, Anesthesiology 1992; 77: 162-184.
2. Lerman J. Surgical and patient factors involved in postoperative nausea and vomiting. British Journal of Anaesthesia 1992; 69 (Suppl. 1): 24S-32S.
3. Korttila K. The study of postoperative nausea and vomiting. British Journal of Anaesthesia 1992; 69 (Suppl. 1): 20S-23S.
4. Haigh CG, Kaplan LA, Durham JM, Dupeyron JP, Harmer M, Kenny GN. Nausea and vomiting after gynaecological surgery : a meta-analysis of factors affecting their incidence. British Journal of Anaesthesia 1993; 71: 517-522.
5. 3 antagonist ondansetron. Anesthesiology 1993; 78: 15-20.
6. Pearman MH. Single dose intravenous ondansetron in the prevention of postoperative nausea and vomiting. Anaesthesia 1994; 49 (Suppl.): 11-15.
7. Aapro MS, Alberts DS. Dexamethasone as an antiemetic in patients treated with cisplatin. New England Journal of Medicine 1981; 305: 520.
8. Smith DB, Newlands ES, Rustin GJ, Begent RH, Howells N, McQuade B, Bagshawe KB. Comparison of ondansetron and ondansetron plus dexamethasone as antiemetic prophylaxis during cisplatin containing chemotherapy. Lancet 1991; 338: 487-490.
9. Drapkin RL, Sokl GH. The antiemetic effect and dose response of dexamethasone in patients receiving cis-platinum Proceedings of the American Society of Clinical Oncology 1982; 1: 64.
10. Jones AL, Hill AS, Soukop M, Hutcheon AW, Cassidy J, Kaye SB, Sikora K, Carney DN, Cunningham D. Comparison of dexamethasone and ondansetron in the prophylaxis of emesis induced by moderately emetogenic chemotherapy. Lancet 1991; 338: 483-486.
11. Allan SG, Leonard RCF. Dexamethasone antiemesis and side-effects. Lancet 1986; 1 1035.
12. Kenny GNC. Risk factors for postoperative nausea and vomiting. Anaesthesia 1994; 49 (Suppl.): 6-10.
13. Helmers JH, Briggs L, Abrahamsson J, Soni J, Moodley J, Forrler M, Hellstein K. A single iv dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. Canadian Journal of Anaesthesia 1993; 40: 1155-1161.
14. Rust M, Cohen LA. Single oral dose ondansetron in the prevention of postoperative nausea and emesis. Anaesthesia 1994; 49 (Suppl.): 16-23.
15. McKenzie R, Kovac A, O'Connor T, Duncalf D, Angel J, Gratz I, Tolpin E, McLeskey C, Joslyn A. Comparison of ondansetron versus placebo to prevent postoperative nausea and vomiting in women undergoing ambulatory gynecologic surgery. Anesthesiology 1993; 78: 21-28.
16. 3 receptor antagonist. Anesthesia and Analgesia 1991; 72: 751-755.
17. Kenny GNC, Oates JD, Leeser J, Rowbotham DJ, Lip H, Rust M, Saur P, Onsrud M, Haigh CG. Efficacy of orally administered ondansetron in the prevention of postoperative nausea and vomiting: a dose ranging study. British Journal of Anaesthesia 1992; 68: 466-470.
18. Joslyn AF. Ondansetron, clinical development for postoperative nausea and vomiting: current studies and future directions. Anaesthesia 1994; 49 (Suppl.): 34-37.
19. Aapro MS, Plezia PM, Alberts DS, Graham V, Jones SE, Suwit EA, Moun TE. Double-blind cross-over study of the antiemetic efficacy of high-dose dexamethasone versus high-dose metoclopramide. Journal of Clinical Oncology 1984; 2: 466-471.
20. Fredrikson M, Hursti T, Furst CJ, Steineck G, Borjeson S, Wikblom M, Peterson C. Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion. British Journal of Cancer 1992; 65: 779-780.
21. Livera P, Trojano M, Simone IL. Acute changes in blood CSF barrier permselectivity to serum protein after intrathecal methotrexate and CNS irradiation. Journal of Neurology 1985, 231: 336-339.
22. Brady ME, Sartiano GP, Rosenblum JL, Zaglema NE, Bauguess CT. The pharmacokinetics of single high dose of dexamethasone in cancer patients. European Journal of Clinical Pharmacology 1987; 32: 593-596.
23. 3 antagonists in postoperative nausea and vomiting. British Journal of Anaesthesia 1992; 69 (Suppl. 1): 63S-68S.
24. Mataruski MR, Keis NA, Smouse DJ, Workman ML. Effects of steroids on postoperative nausea and vomiting. Nurse Anesthesia 1990; 1: 183-188.
25. Yoshitaka F, Hiroyoshi T, Hidenori T. Granisetron-dexamethasone combination reduces postoperative nausea and vomiting. Canadian Journal of Anaesthesia 1995; 42: 387-390.
26. McKenzie R, Tantisira B, Karambelkar DJ, Riley TJ, Abdelhady H. Comparison of ondansetron with ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting. Anesthesia and Analgesia 1994; 79: 961-964.
27. Uthoff K, Zehr KJ, Gaudin PB, Kumar P, Cho PW, Vogelsang G, Hruban RH, Baungartner WA, Stuart RS. Thalidomide as replacement for steroids in immunosupression after lung transplantation. Annals of Thoracic Surgery 1995 59: 277-282.
28. Min DI, Monaco AP. Complications associated with immunosuppressive therapy and their management. Pharmacotherapy 1991; 11: 119S-125S.