Inhibition by platelets of in vitro blastogenic responses of canine PBMC by a PAF-dependent mechanism

Veterinary Immunology and Immunopathology

Volumn 52, Issue 3, 1996, Pages 135-145

  Schreuer, Damien ^a   Hammerberg, Bruce ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

blastogenesis; dogs; lymphocyte; platelet activating factor; platelets

Indexed keywords

SRI 63759; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DOG; FEMALE; FLOW CYTOMETRY; LYMPH NODE CELL; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; THROMBOCYTE;

ANIMALIA; CANIS FAMILIARIS;

EID: 0030003212     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2427(95)05549-5     Document Type: Article

References (16)

1. Barta, O., Waltman, C., Shaffer, L.M., and Oyekan, P.P., 1982. Effect of serum on lymphocyte blastogenesis I. Basic characteristics of action by diseased dog serum. Vet. Immunol. Immunopathol., 3: 567-583.
2. Boogaerts, M.A., Vercelotti, G., Roelant, C., Malbrain, S., Verwilghen, R.L. and Jacob, H.S., 1986. Platelets augment granulocyte aggregation and cytotoxicity: uncovering of their effects by improved cell separation techniques using Percoll gradients. Scand. J. Haematol., 37: 229-236.
3. Boyum, A., 1968. Isolation of mononuclear cells and granulocytes from human. Scand. J. Clin. Invest., 21(Suppl. 97): 77-90.
4. Braquet, R. and Rola-Pleszczynski, M., 1987. Platelet-activating factor and cellular immune responses. Immunol. Today, 8: 345-352.
5. Casella, G. and Berger, R.L., 1990. Statistical Inference. Wadsworth and Brooks/Cole Advanced Books and Software, Pacific Grove, CA, pp. 328-331.
6. Felsburg, P.J., Serra, D.A., Mandato, V.N. and Jezyk, P.M., 1983. Potentiation of the canine lymphocyte blastogenic response by indomethacin. Vet. Immunol. Immunopathol., 4; 533-543.
7. Garvey, J.S., Crenmer, N.E. and Sussdorf, D.H., 1977. Methods in Immunology. The Benjamin/Cummings Publishing Company, Reading, MA, pp. 486-497.
8. Gebhard, D.H. and Carter, P.B., 1992. Identification of canine T-lymphocyte subsets with monoclonal antibodies. Vet. Immunol. Immunopathol., 33: 187-190.
9. Krakowka, S., Cockerell, G. and Koestner, A., 1975. Effects of canine distemper virus infection on lymphoid function in vitro and in vivo. Infect. Immun., 11: 1069-1078.
10. Kristensen, B., Kristensen, F., Vandevelse, M., Higgins, R.J. and DeWeck, A.L., 1982, Canine lymphocyte cultures in vitro: evaluation of peripheral blood lymphocyte response to mitogens. Vet. Immunol. Immunopathol., 3: 439-448.
11. Miller, S., Schreuer, D. and Hammerberg, B., 1991. Inhibition of antigen-driven proliferative responses and enhancement of antibody production during infection with Brugia pahangi. J. Immunol., 147: 1007-1013.
12. Rola-Pleszczynski, M., Pignol, B. and Braquet, P., 1987. Inhibition of human lymphocyte proliferation and interleukin 2 production by platelet activating factor (PAF-acether): reversal by a specific antagonist BN52021. Biochem. Biophys. Res. Commun., 142: 754-760.
13. Segal, N.H., 1985. Lymphocyte activation. In: T. Yoshida (Editor), Investigation of Cell-mediated Immunology. Churchill Livingston, London, pp. 136-137.
14. Thilsted, J.P. and Shifrine, M., 1977. Lymphocyte transformation in the dog: response of lymphocytes from normal and immune dogs to phytohemagglutinin, coccidioidin and purified-protein derivative. Am. J. Vet. Res., 38: 81-87.
15. Waithe, W.I. and Hirschhorn, K., 1978. Lymphocyte response to activators. In: D.M. Weir (Editor), Handbook of Experimental Immunology. Blackwell Scientific Publications, Oxford, pp. 26.4-26.5.
16. Wunderli, P.S. and Felsburg, P.J., 1989. An improved method for the isolation of enriched canine peripheral blood mononuclear cells and peripheral blood lymphocyte preparations. Vet. Immunol. Immunopathol., 20: 335-344.