Postsynaptic mechanisms underlying long-term depression of GABAergic transmission in neurons of the deep cerebellar nuclei

Journal of Neurophysiology

Volumn 76, Issue 1, 1996, Pages 59-68

  Morishita, W ^a   Sastry, B R ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b 2176 Health Sciences Mall   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALCIUM CHANNEL BLOCKING AGENT; CYANOGINOSIN LR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GABOXADOL; LIDOCAINE ETHOBROMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITRENDIPINE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR;

ANIMAL CELL; ARTICLE; BRAIN SLICE; CALCIUM CELL LEVEL; CEREBELLUM NUCLEUS; CONTROLLED STUDY; DEPRESSION; ENZYME ACTIVITY; GABAERGIC TRANSMISSION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MEMBRANE POTENTIAL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP;

EID: 0030003203     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.76.1.59     Document Type: Article

References (35)

1. AUDINAT, E., GÄHWILER, B. H., AND KNÖPFEL, T. Excitatory synaptic potentials in neurones of the deep nuclei in olivo-cerebellar slice cultures. Neuroscience 49: 903-911, 1992.
2. AUDINAT, E., KNÖPFEL, T., AND GÄHWILER, B. H. Responses to excitatory amino acids of Purkinje cells and neurones of the deep nuclei in cerebellar slice cultures. J. Physiol Lond. 430: 297-313, 1990.
3. BLANTON, M. G., LO TURCO, J. J., AND KRIEGSTEIN, A. R. Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex. J. Neurosci. Methods 30: 203-210, 1989.
4. A receptor function is regulated by phosphorylation in acutely dissociated guinea-pig hippocampal neurones. J. Physiol. Lond. 420:207-221, 1990.
5. A receptor responses by NMDA application in hippocampal neurones acutely isolated from the adult guinea-pig. J. Physiol. Lond. 482.2: 353-362, 1995.
6. FORSCHER, P. AND OXFORD, G. S. Modulation of calcium channels by norepinephrine in internally dialyzed avian sensory neurons. J. Gen. Physiol. 85: 743-763, 1985.
7. HORN, R. AND MARTY, A. Muscarinic activation of ionic currents measured by a new whole-cell recording method. J. Gen. Physiol. 92: 145-159, 1988.
8. KANO, M. AND KONNERTH, A. Potentiation of GABA-mediated currents by cAMP-dependent protein kinase. NeuroReport 3: 563-566, 1992.
9. KOMATSU, Y. AND IWAKIRI, M. Long-term modification of inhibitory synaptic transmission in developing visual cortex. NeuroReport 4: 907-910, 1993.
10. KRISHEK, B. J., XIE, X., BLACKSTONE, C., HUGANIR, L., MOSS, S. J., AND SMART, T. G. Regulation of GABA receptor function by protein kinase C phosphorylation. Neuron 12: 1081-1095, 1994.
11. 2+-dependent phosphatase. Nature Lond. 369: 235-239, 1994.
12. LLANO, I., LERESCHE, N., AND MARTY, A. Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron 6: 565-574, 1991.
13. LUNÁS, R. The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science Wash. DC 242: 1654-1664, 1988.
14. MCDONALD, B. J. AND MOSS, S. J. Differential phosphorylation of intracellular domains of γ-aminobutyric acid type A receptor subunits by calcium/calmodulin type 2-dependent protein kinase and cGMP dependent protein kinase. J. Biol. Chem. 269: 18111-18117, 1994.
15. 2+ facilitates long-term potentiation of hippocampal IPSPs. NeuroReport 2: 533-536, 1991.
16. MORISHITA, W. AND SASTRY, B. R. Long-term depression of IPSPs in rat deep cerebellar nuclei. NeuroReport 4: 719-722, 1993.
17. B receptors in the deep nuclei of rat cerebellar slices. Neuroscience 68: 1127-1137, 1995.
18. A receptors by cAMP-dependent protein phosphorylation. Science Wash. DC 257: 661-665 1992.
19. MOUGINOT, D. AND GÄHWILER, B. H. Characterization of synaptic connections between cortex and deep nuclei of the rat cerebellum in vitro. Neuroscience 64: 699-712, 1995.
20. MULKEY, R. M., HERRON, C. E., AND MALENKA, R. C. An essential role for protein phosphatases in hippocampal long-term depression. Science Wash. DC 261: 1051-1055, 1993.
21. MURI, R. AND KNÖPFEL, T. Activity induced elevations of intracellular calcium concentration in neurons of the deep cerebellar nuclei. J. Neurophysiol. 71: 420-428, 1994.
22. A responses in hippocampal pyramidal cells. J. Neurosci. 12: 4122-4132, 1992.
23. PITLER, T. A. AND ALGER, B. E. Depolarization-induced suppression of GABAergic inhibition in rat hippocampal pyramidal cells: G protein involvement in a presynaptic mechanism. Neuron 13: 1447-1455, 1994.
24. SAH, P., HESTRIN, S., AND NICOLL, R. A. Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons. Science Wash. DC 246: 815-818, 1989.
25. SAITOH, Y., YAMAMOTO, H., USHIO, Y., AND MIYAMOTO, E. Characteriztion of polyclonal antibodies to brain protein phosphatase 2A and immunohistochemical localization of the enzyme in rat brain. Brain Res. 489: 291-301, 1989.
26. 2+/calmodulin-dependent kinase II and synapse-enriched phosphoproteins. J. Neurosci. 5: 3414-3422, 1985.
27. A receptor function by N-methyl-D-aspartate-mediated calcium influx in isolated CA1 pyramidal neurons. Neuroscience 62: 813-828, 1994.
28. TAKAHASHI, T. AND MOMIYAMA, A. Different types of calcium channels mediate central synaptic transmission. Nature Lond. 366: 156-158, 1993.
29. TALLANT, E. A. AND CHEUNG, W. Y. Calcium and Cell Function. New York: Academic, 1986, p. 71-112.
30. VINCENT, P., ARMSTRONG, C. M., AND MARTY, A. Inhibitory synaptic currents in rat cerebellar Purkinje cells: modulation by postsynaptic depolarization. J. Physiol. Lond. 456: 453-471, 1992.
31. WALAAS, S. I. AND GREENGARD, P. Protein phosphorylation and neuronal function. Pharmacol. Rev. 43: 299-349, 1991.
32. WANG, L. Y., ORSER, B. A., BRAUTIGAN, D. L., AND MACDONALD, J. F. Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature Lond. 369: 230-232, 1994.
33. WANG, R. A., CHENG, G., KOLAJ, M., AND RANDIĆ, M. α-Subunit of calcium/calmodulin-dependent protein kinase II enhances γ-aminobutyric acid and inhibitory synaptic responses of rat neurons in vitro. J. Neurophysiol. 73: 2099-2106, 1995.
34. 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons. Neuron 12: 127-138, 1994.
35. XIE, Z. AND SASTRY, B. R. Inhibition of protein kinase activity enhances long-term potentiation of hippocampal IPSPs. NeuroReport 2: 389-392, 1991.