Elimination of established liver metastases by human interleukin 2-activated natural killer cells after locoregional or systemic adoptive transfer

Cancer Research

Volumn 56, Issue 7, 1996, Pages 1599-1608

  Okada, Kazuhiko ^a,b   Nannmark, Ulf ^b,c   Vujanovic, Nikola L ^a,b   Watkins, Simon ^a,b   Basse, Per ^a,b   Herberman, Ronald B ^a,b   Whiteside, Theresa L ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; GANGLIOSIDE ANTIBODY; INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 2;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CELL CONTACT; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METASTASIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; STOMACH CARCINOMA;

ANIMALS; FEMALE; HUMANS; IMMUNOTHERAPY, ADOPTIVE; INTERLEUKIN-2; KILLER CELLS, NATURAL; LIVER; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, ELECTRON; TUMOR CELLS, CULTURED;

EID: 0030002909     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Rosenberg, S. A., Yanelli, J. R., Yang, J. C., Topalian, S. L., Schwartzentruber, D. J., Weber, J. S. Parkinson, D. R. Seipp, C. A., Einhorn, J. H , and White, D. E. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J. Natl Cancer Inst., 86; 1159-1166, 1994
2. Rosenberg, S. A., Lotze, M. T., Yang, J. C., Topalian, S. L., Chang, A. E., Schwanzentruber, D. J., Aebersold, P., Leitman, S., Linehan, W. M., Seipp, C. A., White, D. E., and Steinberg, S. M. Prospective randomized trial of high-dose interleukin 2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer. J Natl. Cancer Inst., 85: 622-627, 1993.
3. Basse, P., Herberman, R. B , Nannmark, U., Johansson, E. R., Hokland, M., Wasserman, K., and Goldfarb, R. Accumulation of adoptively transferred A-LAK cells in metastases. J Exp Med., 174: 479-488, 1991.
4. Crowley, N. J., Vervaert, C. E., and Seigler, H. F. Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T cells. Cancer Res., 52: 394-399, 1992.
5. Yasumora, S., Lin, W-c., Hirabayashi, H , Vujanovic, N. L., Herberman, R. B., and Whiteside, T. L. Immunotherapy of liver metastases of human gastric carcinoma with IL-2-activated natural killer cells. Cancer Res., 54: 3808-3816, 1994.
6. Boon, T. Tumor antigens recognized by cytolytic T lymphocytes: present perspectives for specific immunotherapy. Int. J. Cancer, 54. 177-180, 1993.
7. Weidmann, E , Trucco, M , and Whiteside, T. L. Relevance of the T-cell receptor for imiminotherapy of cancer. Cancer Immunol. Immunother., 39: 1-14, 1994.
8. Rabinowich, H., Sedlmayr, P , Herberman, R. B., and Whiteside, T. L. Increased proliferation, lytic activity and purity of natural killer cells co-cultured with mitogen-activated feeder cells Cell. Immunol , 135: 454-470, 1991.
9. Vujanovic, N L., Rabinowich, H., Lee, Y. J , Jost, L , Herberman, R. B., and Whiteside, T. L. Characteristics of human natural killer cells obtained by rapid interleukin 2-induced adherence to plastic. Cell Immunol., 151: 133-157, 1993.
10. Vitolo, D., Vujanovic, N., Rabinowich, H., Schlesinger, M., Herberman, R. B., and Whiteside, T L Rapid interleukin-2 induced adherence of human natural killer (NK) cells accompanied by expression of mRNA for cytokines and IL2 receptors J Immunol., 151: 1926-1937, 1993.
11. Shimizu, Y., Weidmann, E., Iwatsuki, S., Herberman, R. B., and Whiteside, T. L. Characterization of human autotumor-reactive T-cell clones obtained from tumor-infiltrating lymphocytes in liver metastasis of gastric carcinoma. Cancer Res , 51: 6153-6162, 1991.
12. Whiteside, T. L., Bryant, J., Day, R., and Herberman, R. B. Natural killer cytotoxicity in the diagnosis of immune dysfunction: criteria for a reproducible assay. J Clin. Lab Anal., 4: 102-114, 1990
13. Pross, H F., Barnes, M. G , Rubin, P., Shragge, P., and Patterson, M. S Spontaneous human lymphocyte mediated cytotoxicity against tumor target cells IX The quantitation of natural killer cell activity J. Clin. Immunol., 1: 51-63, 1981.
14. Vujanovic, N. L , Yasumura, S., Hirabayastu, H , Lin, W-c., Watkins, S., Herberman, R. B , and Whiteside, T L. Antitumor activities of subsets of human IL2-activated natural killer cells in solid tissues. J. Immunol., 154. 281-289, 1994.
15. Lin, W-c., Pretlow, T. P., Pretlow, T. G., and Culp, L. A. Bacterial lacZ gene as a highly sensitive marker to detect micro metastasis formation during tumor progression. Cancer Res., 50: 2808-2817, 1990.
16. Basse, P , Herberman, R B., Hokland, M., and Goldfarb, R. H. Tissue distribution of adoptively-transferred adherent lymphokine-activated killer cells assessed by different cell labels Cancer Immunol Immunother., 34: 221-227, 1992.
17. Toes, R. E. M , den Haan, J. M. M., Fehkamp, M. C. W., Blom, R. J. J., Mehef, C J M , Claasen, E , and Kast, W M. In vivo detection of fluorescent tumor-specific cytotoxic T-cell clones. J Immunol. Methods, 163: 23-32, 1993.
18. Basse, P. H. Herberman, R. B , Hokland, M. E., and Goldfarb, R H Tissue distribution of adoptively-transferred adherent LAK cells: role of route of administration. Nat. Immun., 11: 193-202, 1992.
19. Basse, P H , Goldfarb, R. H., Herberman, R. B , and Hokland, M. E. Accumulation of adoptively-transferred A-NK cells in murine metastases: kinetics and role of interleukin 2. In Vivo (Athens), 8. 17-24, 1994
20. Maghazachi, A A , and Fitzgibbon, L. Fate of intravenously administered rat lymphocyte activated killer cells labeled with different markers. Cancer Immunol Immunother , 31: 139-145, 1990.
21. Mukherji, B , Ambjarnarson, O , Spitznagle, L A., Hoffman, J., Ergin, M. T. and Spencer, R. B. Biodistribution of 1N-111 labeled tumor sensitized autologous lymphocytes in cancer patients. Prog. Clin Biol. Res , 244: 325-334, 1987.
22. Whiteside, T. L., and Herberman, R. B. Extravasation of antitumor effector cells. Invasion & Metastasis, 72: 128-146, 1992
23. Kuppen, R J. K., Basse, P H , Goldfarb, R H., Van De Velde, C J. H , Fleuren, G. J , and Eggermont, A M M. The infiltration of experimentally-induced lung metastases of colon carcinoma CC531 by adoptively-transferred interleukin 2-activated natural killer cells in Wag rats. Int. J. Cancer, 56: 574-579, 1994
24. Fisher, B., Packard, B. S., Read, E J , Carrasquillo, J. A., Carter, C. S., Topalian, S. L., Yang, J. C., Yolles, P., Larson, S. M , and Rosenberg, S. A. Tumor localization of adoptively transferred indium-111 labeled tumor infiltrating lymphocytes in patients with metastatic melanoma. J. Clin Oncol , 7. 250-261, 1989.
25. Alexander, R. B., and Rosenberg, S. A Adoptively transferred tumor-infiltrating lymphocytes can cure established metastatic tumor in mice and persist long-term in vivo as functional memory T lymphocytes J. Immunother., 10 389-397, 1991
26. Wallace, P. K., Palmer, L D., Perry-Lalley, D , Bolton, E. S., Alexander, R B , Horan, P K., Yang, J. C., and Muirhead, K. A. Mechanisms of adoptive immunotherapy improved methods for in vivo tracking of tumor-infiltrating lymphocytes and tymphokine-activated killer cells Cancer. Res., 53: 2358-2367, 1993
27. Lotze, M. T., Lin,. B. R., Mathiesen, D. J , and Rosenberg, S. A. The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCG). Implications for the adoptive immunotherapy of tumors J. Immunol. 125: 1487-1493, 1980.
28. Rabinowich, H., Vitolo, D., Altarac, S., Herberman, R. B , and Whiteside, T. L. Role of cytokines in the adoptive immunotherapy of an experimental model of human head and neck cancer by human IL2-activated natural killer cells. J. Immunol. 149, 340-349, 1992.
29. Sacchi, M., Vitolo, D., Sedlmayr, P., Rabinowich, H., Johnson, J. T., Herberman, R. B., and Whiteside, T. L. Induction of tumor regression in experimental model of human head and neck cancer by human A-LAK cells and IL2. Int. J Cancer, 47 784-791, 1991.
30. Schwarz, R. E., Vujanovic, N. L., and Hiserodt, J. C. Enhanced antimetastatic activity of lymphokine-activated killer cells purified and expanded by their adherence to plastic. Cancer Res., 49. 1441-1446, 1989.
31. Vujanovic, N. L., Begovic, M., Herberman, R. B., and Whiteside, T. L. The mechanisms of breast cancer cell killing by human natural killer cells. FASEB J., 8: A209, 1994.
32. Beutler, B., and Van Hoffel, C Unraveling function in the TNF ligand and receptor families. Science (Washington DC), 264: 667-668, 1994.
33. 1 cell cycle arrest and changes in susceptibility of SCCHN to lysis induced by soluble factors produced by human IL2-activated natural killer cells Nat. Immun., 13: A231, 1994.
34. Riccardi, C., Barlozzari, T., Santoni, A., Herberman, R. B., and Cesanni, C Transfer to cyclophosphamide-treated mice of natural killer (NK) cells in vivo natural reactivity against tumors J. Immunol., 126: 1284-1289, 1981.
35. Gorelik, E., Wiltrout, R. H , Okumura, K., Habu, S., and Herberman, R. B. Role of NK cells in the control of metastatic spread and growth of tumor cells in mice. Int J. Cancer, 50: 107-112, 1982.
36. Pross, H. F., and Lotzova, E. Role of natural killer cells in cancer. Nat. Immun , 12, 279-292, 1993