Myosin regulatory light chain modulates the Ca2+ dependence of the kinetics of tension development in skeletal muscle fibers

Biophysical Journal

Volumn 70, Issue 5, 1996, Pages 2333-2340

  Patel, Jitandrakumar R ^a   Diffee, Gary M ^a,b   Moss, Richard L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN LIGHT CHAIN; TROPONIN C;

ACTIN MYOSIN INTERACTION; ANIMAL TISSUE; ARTICLE; ARTIFACT; CALCIUM TRANSPORT; MUSCLE FIBER CONTRACTION; MUSCLE TONE; NONHUMAN; PROTEIN DETERMINATION; RABBIT; SKELETAL MUSCLE;

ANIMALS; CALCIUM; KINETICS; MAGNESIUM; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE FIBERS, FAST-TWITCH; MUSCLE, SKELETAL; MYOSIN LIGHT CHAINS; PHOTOLYSIS; RABBITS; TIME FACTORS; TROPONIN C;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030002797     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(96)79799-0     Document Type: Article

References (30)

1. 2+ Am. J. Physiol. 267:H1643-H1653.
2. 2+ and activation mechanisms in skeletal muscle. Q. Rev. Biophys. 24:1-73.
3. Bagshaw, C. R., and G. H. Reed. 1977. The significance of the slow dissociation of divalent metal ions from myosin "regulatory" light chains. FEBS Lett. 81:386-390
4. 2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction. Proc. Natl. Acad. Sci. USA. 85:3265-3269.
5. Brenner, B., and E. Eisenberg. 1986. Rate of force generation in muscle: correlation with actomyosin ATPase activity in solution. Proc. Natl. Acad. Sci. USA. 83:3542-3546.
6. 2+. Biophys. J. 67:1994-2001.
7. Diffee, G. M., M. L. Greaser, F. Reinach, and R. L. Moss. 1995. Effects of a non-divalent cation binding mutant of myosin regulatory light chain on tension generation in skinned skeletal muscle fibers. Biophys. J. 68: 1443-1452.
8. Fabiato, A. 1988. Computer programs for calculating total from specified free and free from specified total ionic concentrations in aqueous solutions containing multiple metals or ligands. Methods Enzymol. 157: 378-417.
9. Godt, R. E., and B. D. Lindley. 1982. Influence of temperature upon contractile activation and isometric force production in mechanically skinned muscle fibers of the frog. J. Gen. Physiol. 80:279-297.
10. Goodwin, E. B., L. A. Leinwand, and A. G. Szent-Gyorgi. 1990. Regulation of scallop myosin by mutant regulatory light chains. J. Mol. Biol. 216:85-93.
11. Greaser, M. L., and J. Gergely. 1971. Reconstitution of troponia activity from three protein components. J. Biol. Chem. 246:4226-4233.
12. 2+ sensitivities of isometric tension, stiffness, and velocity of shortening in skinned skeletal muscle fibers. J. Gen. Physiol. 95:477-498.
13. Holroyde, M. J., J. D. Potter, and R. J. Solaro. 1979. The calcium binding properties of phosphorylated and unphosphorylated cardiac and skeletal myosins. J. Biol. Chem. 254:6478-6482.
14. Kamm, K. E., and J. T. Stull. 1985. The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu. Rev. Pharmacol. Toxicol. 25.593-620.
15. Kaplan, J. H., and G. C. R. Ellis-Davies. 1988. Photolabile chelators for the rapid photorelease of divalent cations. Proc. Natl. Acad. Sci. USA. 85:6571-6575
16. Kwon, H., E. B. Goodwin, L. Nyitray, E. Berliner, E. O'Neall-Hennessey, F. D. Melandri, and A. G. Szent-Gyorgi. 1990. Isolation of the regulatory domain of scallop myosin: role of the essential light chain in calcium binding. Proc. Natl. Acad. Sci. USA. 87:4771-4770.
17. 2+. In Mechanism of Myofilament Sliding in Muscle Contraction. H. Sugi and G. H. Pollack, editors. Plenum Press, New York.
18. Lowey, S., and D. Risby. 1971. Light chains from fast and slow myosins. Nature. 234:81-85.
19. Lowey, S., G. S. Waller, and K. M. Trybus. 1993. Skeletal muscle light chains are essential for physiological speeds of shortening. Nature. 365:454-456.
20. 2+ sensitive cross-bridge state transition in skeletal muscle fibers: effects due to variations in thin filament activation by extraction of troponin C. J. Gen. Physiol. 98:233-248.
21. Metzger, J. M., and R. L. Moss. 1992. Myosin light chain 2 modulates calcium-sensitive cross-bridge transitions in vertebrate skeletal muscle. Biophys. J. 63:460-468.
22. 2 from skinned skeletal muscle fibers J. Biol. Chem. 257:8588-8591.
23. Moss, R. L., G. G. Giulian, and M. L. Greaser. 1983. Effects of EDTA treatment upon the protein subunit composition and mechanical properties of mammalian single skeletal muscle fibers. J. Cell Biol. 96: 970-978.
24. Rayment, I., W. R. Rypniewski, K. Schmidt-Bäse, R. Smith, D. R. Tomchick, M. M. Benning, D. A. Winkelmann, G. Wesenberg, and H. M. Holden. 1993. Three-dimensional structure of myosin subfragment-I: a molecular motor Science. 261:50-58.
25. Simmons, R. M., and A. G. Szeni-Gyorgi. 1978. Reversible loss of calcium control of tension in scallop striated muscle associated with the removal of regulatory light chain. Nature. 273:62-64.
26. Swartz, D. R., and R. L. Moss. 1992. Influence of a strong-binding myosin analogue on calcium-sensitive properties of skinned skeletal muscle fibers. J. Biol. Chem. 267:20497-20506.
27. VanBuren, P., G. S. Waller, D. E. Harris, K. M. Trybus, D. M. Warshaw, and S. Lowey. 1994. The essential light chain is required for full force production by skeletal muscle myosin. Proc. Natl. Acad. Sci. USA 91:12403-12407
28. Wagner, P. D. 1982. Preparation and fractionation of myosin light chains and exchange of the essential light chain. Methods Enzymol. 85:72-81.
29. Weeds, A. G., and S. Lowey. 1971. Substructure of the myosin molecule. II. The light chains of myosin. J. Mol. Biol. 61:701-725.
30. Wolff, M. W., K. S. McDonald, R. L. Moss. 1995. Rate of tension development in cardiac muscle varies with the level of activator calcium. Circ. Res. 76:154-160.